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Items: 23


Factors Regulating microRNA Expression and Function in Multiple Myeloma.

Misiewicz-Krzeminska I, Krzeminski P, Corchete LA, Quwaider D, Rojas EA, Herrero AB, Gutiérrez NC.

Noncoding RNA. 2019 Jan 16;5(1). pii: E9. doi: 10.3390/ncrna5010009. Review.


A novel nano-immunoassay method for quantification of proteins from CD138-purified myeloma cells: biological and clinical utility.

Misiewicz-Krzeminska I, Corchete LA, Rojas EA, Martínez-López J, García-Sanz R, Oriol A, Bladé J, Lahuerta JJ, Miguel JS, Mateos MV, Gutiérrez NC.

Haematologica. 2018 May;103(5):880-889. doi: 10.3324/haematol.2017.181628. Epub 2018 Mar 15.


The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma.

Hernández-García S, San-Segundo L, González-Méndez L, Corchete LA, Misiewicz-Krzeminska I, Martín-Sánchez M, López-Iglesias AA, Algarín EM, Mogollón P, Díaz-Tejedor A, Paíno T, Tunquist B, Mateos MV, Gutiérrez NC, Díaz-Rodriguez E, Garayoa M, Ocio EM.

Haematologica. 2017 Dec;102(12):2113-2124. doi: 10.3324/haematol.2017.168666. Epub 2017 Aug 31.


Amiloride, An Old Diuretic Drug, Is a Potential Therapeutic Agent for Multiple Myeloma.

Rojas EA, Corchete LA, San-Segundo L, Martínez-Blanch JF, Codoñer FM, Paíno T, Puig N, García-Sanz R, Mateos MV, Ocio EM, Misiewicz-Krzeminska I, Gutiérrez NC.

Clin Cancer Res. 2017 Nov 1;23(21):6602-6615. doi: 10.1158/1078-0432.CCR-17-0678. Epub 2017 Aug 8.


Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair.

López-Iglesias AA, Herrero AB, Chesi M, San-Segundo L, González-Méndez L, Hernández-García S, Misiewicz-Krzeminska I, Quwaider D, Martín-Sánchez M, Primo D, Paíno T, Bergsagel PL, Mehrling T, González-Díaz M, San-Miguel JF, Mateos MV, Gutiérrez NC, Garayoa M, Ocio EM.

J Hematol Oncol. 2017 Jun 20;10(1):127. doi: 10.1186/s13045-017-0495-y.


A novel capillary nano-immunoassay for assessing androgen receptor splice variant 7 in plasma. Correlation with CD133 antigen expression in circulating tumor cells. A pilot study in prostate cancer patients.

García JL, Lozano R, Misiewicz-Krzeminska I, Fernández-Mateos J, Krzeminski P, Alfonso S, Marcos RA, García R, Gómez-Veiga F, Virseda Á, Herrero M, Olmos D, Cruz-Hernández JJ.

Clin Transl Oncol. 2017 Nov;19(11):1350-1357. doi: 10.1007/s12094-017-1675-5. Epub 2017 Jun 9.


DEPTOR maintains plasma cell differentiation and favorably affects prognosis in multiple myeloma.

Quwaider D, Corchete LA, Misiewicz-Krzeminska I, Sarasquete ME, Pérez JJ, Krzeminski P, Puig N, Mateos MV, García-Sanz R, Herrero AB, Gutiérrez NC.

J Hematol Oncol. 2017 Apr 18;10(1):92. doi: 10.1186/s13045-017-0461-8.


Molecular Mechanisms of p53 Deregulation in Cancer: An Overview in Multiple Myeloma.

Herrero AB, Rojas EA, Misiewicz-Krzeminska I, Krzeminski P, Gutiérrez NC.

Int J Mol Sci. 2016 Nov 30;17(12). pii: E2003. Review.


Microvesicles from Mesenchymal Stromal Cells Are Involved in HPC-Microenvironment Crosstalk in Myelodysplastic Patients.

Muntión S, Ramos TL, Diez-Campelo M, Rosón B, Sánchez-Abarca LI, Misiewicz-Krzeminska I, Preciado S, Sarasquete ME, de Las Rivas J, González M, Sánchez-Guijo F, Del Cañizo MC.

PLoS One. 2016 Feb 2;11(2):e0146722. doi: 10.1371/journal.pone.0146722. eCollection 2016.


Post-transcriptional Modifications Contribute to the Upregulation of Cyclin D2 in Multiple Myeloma.

Misiewicz-Krzeminska I, Sarasquete ME, Vicente-Dueñas C, Krzeminski P, Wiktorska K, Corchete LA, Quwaider D, Rojas EA, Corral R, Martín AA, Escalante F, Bárez A, García JL, Sánchez-García I, García-Sanz R, San Miguel JF, Gutiérrez NC.

Clin Cancer Res. 2016 Jan 1;22(1):207-17. doi: 10.1158/1078-0432.CCR-14-2796. Epub 2015 Sep 4.


MicroRNA-223 is a novel negative regulator of HSP90B1 in CLL.

Rodríguez-Vicente AE, Quwaider D, Benito R, Misiewicz-Krzeminska I, Hernández-Sánchez M, de Coca AG, Fisac R, Alonso JM, Zato C, de Paz JF, García JL, Sarasquete ME, Hernández JÁ, Corchado JM, González M, Gutiérrez NC, Hernández-Rivas JM.

BMC Cancer. 2015 Apr 8;15:238. doi: 10.1186/s12885-015-1212-2.


Insights into epigenetic regulation of microRNA-155 expression in multiple myeloma.

Krzeminski P, Sarasquete ME, Misiewicz-Krzeminska I, Corral R, Corchete LA, Martín AA, García-Sanz R, San Miguel JF, Gutiérrez NC.

Biochim Biophys Acta. 2015 Mar;1849(3):353-66. doi: 10.1016/j.bbagrm.2014.12.002. Epub 2014 Dec 11.


Restoration of microRNA-214 expression reduces growth of myeloma cells through positive regulation of P53 and inhibition of DNA replication.

Misiewicz-Krzeminska I, Sarasquete ME, Quwaider D, Krzeminski P, Ticona FV, Paíno T, Delgado M, Aires A, Ocio EM, García-Sanz R, San Miguel JF, Gutiérrez NC.

Haematologica. 2013 Apr;98(4):640-8. doi: 10.3324/haematol.2012.070011. Epub 2012 Oct 25.


Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2.

Lubelska K, Misiewicz-Krzemińska I, Milczarek M, Krzysztoń-Russjan J, Anuszewska E, Modzelewska K, Wiktorska K.

Mol Cell Biochem. 2012 Aug;367(1-2):19-29. doi: 10.1007/s11010-012-1314-y. Epub 2012 Apr 18.


Combination treatment with 5-fluorouracil and isothiocyanates shows an antagonistic effect in Chinese hamster fibroblast cells line-V79.

Milczarek M, Misiewicz-Krzemińska I, Lubelska K, Wiktorska K.

Acta Pol Pharm. 2011 May-Jun;68(3):331-42.


Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients.

Sarasquete ME, Gutiérrez NC, Misiewicz-Krzeminska I, Paiva B, Chillón MC, Alcoceba M, García-Sanz R, Hernández JM, González M, San-Miguel JF.

Haematologica. 2011 Mar;96(3):468-71. doi: 10.3324/haematol.2010.033845. Epub 2010 Dec 15.


Selenitetriglicerydes affect CYP1A1 and QR activity by involvement of reactive oxygen species and Nrf2 transcription factor.

Suchocki P, Misiewicz-Krzemińska I, Skupińska K, Niedźwiecka K, Lubelska K, Fijałek Z, Kasprzycka-Guttman T.

Pharmacol Rep. 2010 Mar-Apr;62(2):352-61.


Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling.

Gutiérrez NC, Sarasquete ME, Misiewicz-Krzeminska I, Delgado M, De Las Rivas J, Ticona FV, Fermiñán E, Martín-Jiménez P, Chillón C, Risueño A, Hernández JM, García-Sanz R, González M, San Miguel JF.

Leukemia. 2010 Mar;24(3):629-37. doi: 10.1038/leu.2009.274. Epub 2010 Jan 7.


Does molecular docking reveal alternative chemopreventive mechanism of activation of oxidoreductase by sulforaphane isothiocyanates?

Mazur P, Magdziarz T, Bak A, Chilmonczyk Z, Kasprzycka-Guttman T, Misiewicz-Krzemińska I, Skupińska K, Polanski J.

J Mol Model. 2010 Jul;16(7):1205-12. doi: 10.1007/s00894-009-0628-5. Epub 2009 Dec 22.


Decytabine enhances cytotoxicity induced by oxaliplatin and 5-fluorouracil in the colorectal cancer cell line Colo-205.

Flis S, Gnyszka A, Misiewicz-Krzemińska I, Spławiński J.

Cancer Cell Int. 2009 Apr 27;9:10. doi: 10.1186/1475-2867-9-10.


The effect of isothiocyanates on CYP1A1 and CYP1A2 activities induced by polycyclic aromatic hydrocarbons in Mcf7 cells.

Skupinska K, Misiewicz-Krzeminska I, Lubelska K, Kasprzycka-Guttman T.

Toxicol In Vitro. 2009 Aug;23(5):763-71. doi: 10.1016/j.tiv.2009.04.001. Epub 2009 Apr 9.


Sulforaphane and its analogues inhibit CYP1A1 and CYP1A2 activity induced by benzo[a]pyrene.

Skupinska K, Misiewicz-Krzeminska I, Stypulkowski R, Lubelska K, Kasprzycka-Guttman T.

J Biochem Mol Toxicol. 2009 Jan-Feb;23(1):18-28. doi: 10.1002/jbt.20259.


Influence of protoporphyrin IX amino acid substituents on affinity to human breast adenocarcinoma MCF-7 cells.

Misiewicz-Krzemińska I, Skupińska K, Graczyk A, Kasprzycka-Guttman T.

Biotech Histochem. 2009 Feb;84(1):17-23. doi: 10.1080/10520290802673381.


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