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Items: 50

1.

mtDNA Chromatin-like Organization Is Gradually Established during Mammalian Embryogenesis.

Marom S, Blumberg A, Kundaje A, Mishmar D.

iScience. 2019 Feb 22;12:141-151. doi: 10.1016/j.isci.2018.12.032. Epub 2019 Jan 8.

2.

A common pattern of DNase I footprinting throughout the human mtDNA unveils clues for a chromatin-like organization.

Blumberg A, Danko CG, Kundaje A, Mishmar D.

Genome Res. 2018 Aug;28(8):1158-1168. doi: 10.1101/gr.230409.117. Epub 2018 Jul 12.

3.

Mitochondrial DNA associations with East Asian metabolic syndrome.

Chalkia D, Chang YC, Derbeneva O, Lvova M, Wang P, Mishmar D, Liu X, Singh LN, Chuang LM, Wallace DC.

Biochim Biophys Acta Bioenerg. 2018 Sep;1859(9):878-892. doi: 10.1016/j.bbabio.2018.07.002. Epub 2018 Jul 8.

PMID:
29997041
4.

Mitochondrial DNA Transcription and Its Regulation: An Evolutionary Perspective.

Barshad G, Marom S, Cohen T, Mishmar D.

Trends Genet. 2018 Sep;34(9):682-692. doi: 10.1016/j.tig.2018.05.009. Epub 2018 Jun 23. Review.

PMID:
29945721
5.

Human primitive brain displays negative mitochondrial-nuclear expression correlation of respiratory genes.

Barshad G, Blumberg A, Cohen T, Mishmar D.

Genome Res. 2018 Jul;28(7):952-967. doi: 10.1101/gr.226324.117. Epub 2018 Jun 14.

6.

The First Mitochondrial Genomics and Evolution SMBE-Satellite Meeting: A New Scientific Symbiosis.

Ostersetzer-Biran O, Lane N, Pomiankowski A, Burton R, Arnqvist G, Filipovska A, Huchon D, Mishmar D.

Genome Biol Evol. 2017 Nov 1;9(11):3054-3058. doi: 10.1093/gbe/evx227.

7.

The genomic landscape of evolutionary convergence in mammals, birds and reptiles.

Levin L, Mishmar D.

Nat Ecol Evol. 2017 Feb 13;1(3):41. doi: 10.1038/s41559-016-0041.

PMID:
28812724
8.
9.

Correction: Mitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All Vertebrates.

Bar-Yaacov D, Frumkin I, Yashiro Y, Chujo T, Ishigami Y, Chemla Y, Blumberg A, Schlesinger O, Bieri P, Greber B, Ban N, Zarivach R, Alfonta L, Pilpel Y, Suzuki T, Mishmar D.

PLoS Biol. 2017 Jan 19;15(1):e1002594. doi: 10.1371/journal.pbio.1002594. eCollection 2017 Jan.

10.

Initiation of mtDNA transcription is followed by pausing, and diverges across human cell types and during evolution.

Blumberg A, Rice EJ, Kundaje A, Danko CG, Mishmar D.

Genome Res. 2017 Mar;27(3):362-373. doi: 10.1101/gr.209924.116. Epub 2017 Jan 3.

11.

Ancient Out-of-Africa Mitochondrial DNA Variants Associate with Distinct Mitochondrial Gene Expression Patterns.

Cohen T, Levin L, Mishmar D.

PLoS Genet. 2016 Nov 3;12(11):e1006407. doi: 10.1371/journal.pgen.1006407. eCollection 2016 Nov.

12.

Mitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All Vertebrates.

Bar-Yaacov D, Frumkin I, Yashiro Y, Chujo T, Ishigami Y, Chemla Y, Blumberg A, Schlesinger O, Bieri P, Greber B, Ban N, Zarivach R, Alfonta L, Pilpel Y, Suzuki T, Mishmar D.

PLoS Biol. 2016 Sep 15;14(9):e1002557. doi: 10.1371/journal.pbio.1002557. eCollection 2016 Sep. Erratum in: PLoS Biol. 2017 Jan 19;15(1):e1002594.

13.

LEMONS - A Tool for the Identification of Splice Junctions in Transcriptomes of Organisms Lacking Reference Genomes.

Levin L, Bar-Yaacov D, Bouskila A, Chorev M, Carmel L, Mishmar D.

PLoS One. 2015 Nov 25;10(11):e0143329. doi: 10.1371/journal.pone.0143329. eCollection 2015.

14.

Mitochondrial Involvement in Vertebrate Speciation? The Case of Mito-nuclear Genetic Divergence in Chameleons.

Bar-Yaacov D, Hadjivasiliou Z, Levin L, Barshad G, Zarivach R, Bouskila A, Mishmar D.

Genome Biol Evol. 2015 Nov 19;7(12):3322-36. doi: 10.1093/gbe/evv226.

15.

A genetic view of the mitochondrial role in ageing: killing us softly.

Levin L, Mishmar D.

Adv Exp Med Biol. 2015;847:89-106. doi: 10.1007/978-1-4939-2404-2_4. Review.

PMID:
25916587
16.

Mito-nuclear co-evolution: the positive and negative sides of functional ancient mutations.

Levin L, Blumberg A, Barshad G, Mishmar D.

Front Genet. 2014 Dec 23;5:448. doi: 10.3389/fgene.2014.00448. eCollection 2014. Review.

17.

Parkin modulates heteroplasmy of truncated mtDNA in Caenorhabditis elegans.

Valenci I, Yonai L, Bar-Yaacov D, Mishmar D, Ben-Zvi A.

Mitochondrion. 2015 Jan;20:64-70. doi: 10.1016/j.mito.2014.11.001. Epub 2014 Nov 15.

PMID:
25462019
18.

Disrupting mitochondrial-nuclear coevolution affects OXPHOS complex I integrity and impacts human health.

Gershoni M, Levin L, Ovadia O, Toiw Y, Shani N, Dadon S, Barzilai N, Bergman A, Atzmon G, Wainstein J, Tsur A, Nijtmans L, Glaser B, Mishmar D.

Genome Biol Evol. 2014 Sep 22;6(10):2665-80. doi: 10.1093/gbe/evu208.

19.

Transcription factors bind negatively selected sites within human mtDNA genes.

Blumberg A, Sri Sailaja B, Kundaje A, Levin L, Dadon S, Shmorak S, Shaulian E, Meshorer E, Mishmar D.

Genome Biol Evol. 2014 Sep 22;6(10):2634-46. doi: 10.1093/gbe/evu210.

20.

The first Chameleon transcriptome: comparative genomic analysis of the OXPHOS system reveals loss of COX8 in Iguanian lizards.

Bar-Yaacov D, Bouskila A, Mishmar D.

Genome Biol Evol. 2013;5(10):1792-9. doi: 10.1093/gbe/evt131.

21.

RNA-DNA differences in human mitochondria restore ancestral form of 16S ribosomal RNA.

Bar-Yaacov D, Avital G, Levin L, Richards AL, Hachen N, Rebolledo Jaramillo B, Nekrutenko A, Zarivach R, Mishmar D.

Genome Res. 2013 Nov;23(11):1789-96. doi: 10.1101/gr.161265.113. Epub 2013 Aug 2.

22.

Functional recurrent mutations in the human mitochondrial phylogeny: dual roles in evolution and disease.

Levin L, Zhidkov I, Gurman Y, Hawlena H, Mishmar D.

Genome Biol Evol. 2013;5(5):876-90. doi: 10.1093/gbe/evt058.

23.

Mitochondrial DNA heteroplasmy in diabetes and normal adults: role of acquired and inherited mutational patterns in twins.

Avital G, Buchshtav M, Zhidkov I, Tuval Feder J, Dadon S, Rubin E, Glass D, Spector TD, Mishmar D.

Hum Mol Genet. 2012 Oct 1;21(19):4214-24. doi: 10.1093/hmg/dds245. Epub 2012 Jun 26.

24.

Mitochondrial DNA variation, but not nuclear DNA, sharply divides morphologically identical chameleons along an ancient geographic barrier.

Bar Yaacov D, Arbel-Thau K, Zilka Y, Ovadia O, Bouskila A, Mishmar D.

PLoS One. 2012;7(3):e31372. doi: 10.1371/journal.pone.0031372. Epub 2012 Mar 13.

25.

Mitochondrial-nuclear co-evolution and its effects on OXPHOS activity and regulation.

Bar-Yaacov D, Blumberg A, Mishmar D.

Biochim Biophys Acta. 2012 Sep-Oct;1819(9-10):1107-11. doi: 10.1016/j.bbagrm.2011.10.008. Epub 2011 Oct 22. Review.

PMID:
22044624
26.

MitoBamAnnotator: A web-based tool for detecting and annotating heteroplasmy in human mitochondrial DNA sequences.

Zhidkov I, Nagar T, Mishmar D, Rubin E.

Mitochondrion. 2011 Nov;11(6):924-8. doi: 10.1016/j.mito.2011.08.005. Epub 2011 Aug 22.

PMID:
21875693
27.

CHILD: a new tool for detecting low-abundance insertions and deletions in standard sequence traces.

Zhidkov I, Cohen R, Geifman N, Mishmar D, Rubin E.

Nucleic Acids Res. 2011 Apr;39(7):e47. doi: 10.1093/nar/gkq1354. Epub 2011 Jan 28.

28.

Coevolution predicts direct interactions between mtDNA-encoded and nDNA-encoded subunits of oxidative phosphorylation complex i.

Gershoni M, Fuchs A, Shani N, Fridman Y, Corral-Debrinski M, Aharoni A, Frishman D, Mishmar D.

J Mol Biol. 2010 Nov 19;404(1):158-71. doi: 10.1016/j.jmb.2010.09.029. Epub 2010 Sep 22.

PMID:
20868692
29.

Copy number variation of the SELENBP1 gene in schizophrenia.

Amar S, Ovadia O, Maier W, Ebstein R, Belmaker RH, Mishmar D, Agam G.

Behav Brain Funct. 2010 Jul 8;6:40. doi: 10.1186/1744-9081-6-40.

30.

The impact of darwinian evolution on medicine: the maternal side of the story.

Mishmar D.

Rambam Maimonides Med J. 2010 Jul 2;1(1):e0010. doi: 10.5041/RMMJ.10010. Print 2010 Jul.

31.

Gene expression patterns of oxidative phosphorylation complex I subunits are organized in clusters.

Garbian Y, Ovadia O, Dadon S, Mishmar D.

PLoS One. 2010 Apr 1;5(4):e9985. doi: 10.1371/journal.pone.0009985.

32.

Evolution and disease converge in the mitochondrion.

Mishmar D, Zhidkov I.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1099-104. doi: 10.1016/j.bbabio.2010.01.003. Epub 2010 Jan 13. Review.

33.

Parental diabetes status reveals association of mitochondrial DNA haplogroup J1 with type 2 diabetes.

Feder J, Ovadia O, Blech I, Cohen J, Wainstein J, Harman-Boehm I, Glaser B, Mishmar D.

BMC Med Genet. 2009 Jun 18;10:60. doi: 10.1186/1471-2350-10-60.

34.

Ancient mtDNA genetic variants modulate mtDNA transcription and replication.

Suissa S, Wang Z, Poole J, Wittkopp S, Feder J, Shutt TE, Wallace DC, Shadel GS, Mishmar D.

PLoS Genet. 2009 May;5(5):e1000474. doi: 10.1371/journal.pgen.1000474. Epub 2009 May 8.

35.

Mitochondrial bioenergetics as a major motive force of speciation.

Gershoni M, Templeton AR, Mishmar D.

Bioessays. 2009 Jun;31(6):642-50. doi: 10.1002/bies.200800139. Review.

PMID:
19408245
36.

MtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints.

Zhidkov I, Livneh EA, Rubin E, Mishmar D.

Genome Res. 2009 Apr;19(4):576-80. doi: 10.1101/gr.086462.108. Epub 2009 Feb 10.

37.

A novel NDUFA1 mutation leads to a progressive mitochondrial complex I-specific neurodegenerative disease.

Potluri P, Davila A, Ruiz-Pesini E, Mishmar D, O'Hearn S, Hancock S, Simon M, Scheffler IE, Wallace DC, Procaccio V.

Mol Genet Metab. 2009 Apr;96(4):189-95. doi: 10.1016/j.ymgme.2008.12.004. Epub 2009 Jan 29.

38.

Assembling an arsenal, the scorpion way.

Kozminsky-Atias A, Bar-Shalom A, Mishmar D, Zilberberg N.

BMC Evol Biol. 2008 Dec 16;8:333. doi: 10.1186/1471-2148-8-333.

39.

MITOMASTER: a bioinformatics tool for the analysis of mitochondrial DNA sequences.

Brandon MC, Ruiz-Pesini E, Mishmar D, Procaccio V, Lott MT, Nguyen KC, Spolim S, Patil U, Baldi P, Wallace DC.

Hum Mutat. 2009 Jan;30(1):1-6. doi: 10.1002/humu.20801.

40.

Differences in mtDNA haplogroup distribution among 3 Jewish populations alter susceptibility to T2DM complications.

Feder J, Blech I, Ovadia O, Amar S, Wainstein J, Raz I, Dadon S, Arking DE, Glaser B, Mishmar D.

BMC Genomics. 2008 Apr 29;9:198. doi: 10.1186/1471-2164-9-198.

41.

Mitochondrial DNA HV lineage increases the susceptibility to schizophrenia among Israeli Arabs.

Amar S, Shamir A, Ovadia O, Blanaru M, Reshef A, Kremer I, Rietschel M, Schulze TG, Maier W, Belmaker RH, Ebstein RP, Agam G, Mishmar D.

Schizophr Res. 2007 Aug;94(1-3):354-8. Epub 2007 Jun 12.

PMID:
17566709
42.

Ashkenazi Jewish mtDNA haplogroup distribution varies among distinct subpopulations: lessons of population substructure in a closed group.

Feder J, Ovadia O, Glaser B, Mishmar D.

Eur J Hum Genet. 2007 Apr;15(4):498-500. Epub 2007 Jan 24.

43.

An enhanced MITOMAP with a global mtDNA mutational phylogeny.

Ruiz-Pesini E, Lott MT, Procaccio V, Poole JC, Brandon MC, Mishmar D, Yi C, Kreuziger J, Baldi P, Wallace DC.

Nucleic Acids Res. 2007 Jan;35(Database issue):D823-8. Epub 2006 Dec 18.

44.

Adaptive selection of mitochondrial complex I subunits during primate radiation.

Mishmar D, Ruiz-Pesini E, Mondragon-Palomino M, Procaccio V, Gaut B, Wallace DC.

Gene. 2006 Aug 15;378:11-8. Epub 2006 Jul 7.

PMID:
16828987
45.

mtDNA variation, climatic adaptation, degenerative diseases, and longevity.

Wallace DC, Ruiz-Pesini E, Mishmar D.

Cold Spring Harb Symp Quant Biol. 2003;68:479-86. Review. No abstract available.

PMID:
15338651
46.
47.

Effects of purifying and adaptive selection on regional variation in human mtDNA.

Ruiz-Pesini E, Mishmar D, Brandon M, Procaccio V, Wallace DC.

Science. 2004 Jan 9;303(5655):223-6.

48.

Natural selection shaped regional mtDNA variation in humans.

Mishmar D, Ruiz-Pesini E, Golik P, Macaulay V, Clark AG, Hosseini S, Brandon M, Easley K, Chen E, Brown MD, Sukernik RI, Olckers A, Wallace DC.

Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):171-6. Epub 2002 Dec 30.

49.

Common fragile sites: G-band characteristics within an R-band.

Mishmar D, Mandel-Gutfreund Y, Margalit H, Rahat A, Kerem B.

Am J Hum Genet. 1999 Mar;64(3):908-10. No abstract available. Erratum in: Am J Hum Genet 1999 Apr;64(4):1257.

50.

Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

Mishmar D, Rahat A, Scherer SW, Nyakatura G, Hinzmann B, Kohwi Y, Mandel-Gutfroind Y, Lee JR, Drescher B, Sas DE, Margalit H, Platzer M, Weiss A, Tsui LC, Rosenthal A, Kerem B.

Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8141-6.

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