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Items: 24


Single cell analysis of clonal architecture in acute myeloid leukaemia.

Potter N, Miraki-Moud F, Ermini L, Titley I, Vijayaraghavan G, Papaemmanuil E, Campbell P, Gribben J, Taussig D, Greaves M.

Leukemia. 2019 May;33(5):1113-1123. doi: 10.1038/s41375-018-0319-2. Epub 2018 Dec 19.


Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells.

Casado P, Wilkes EH, Miraki-Moud F, Hadi MM, Rio-Machin A, Rajeeve V, Pike R, Iqbal S, Marfa S, Lea N, Best S, Gribben J, Fitzgibbon J, Cutillas PR.

Leukemia. 2018 Aug;32(8):1818-1822. doi: 10.1038/s41375-018-0032-1. Epub 2018 Apr 7. No abstract available.


Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo.

Miraki-Moud F, Ghazaly E, Ariza-McNaughton L, Hodby KA, Clear A, Anjos-Afonso F, Liapis K, Grantham M, Sohrabi F, Cavenagh J, Bomalaski JS, Gribben JG, Szlosarek PW, Bonnet D, Taussig DC.

Blood. 2015 Jun 25;125(26):4060-8. doi: 10.1182/blood-2014-10-608133. Epub 2015 Apr 20.


Loss of imprinting at the 14q32 domain is associated with microRNA overexpression in acute promyelocytic leukemia.

Manodoro F, Marzec J, Chaplin T, Miraki-Moud F, Moravcsik E, Jovanovic JV, Wang J, Iqbal S, Taussig D, Grimwade D, Gribben JG, Young BD, Debernardi S.

Blood. 2014 Mar 27;123(13):2066-74. doi: 10.1182/blood-2012-12-469833. Epub 2014 Feb 3.


Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation.

Miraki-Moud F, Anjos-Afonso F, Hodby KA, Griessinger E, Rosignoli G, Lillington D, Jia L, Davies JK, Cavenagh J, Smith M, Oakervee H, Agrawal S, Gribben JG, Bonnet D, Taussig DC.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13576-81. doi: 10.1073/pnas.1301891110. Epub 2013 Jul 30.


Acid-labile subunit deficiency and growth failure: description of two novel cases.

David A, Rose SJ, Miraki-Moud F, Metherell LA, Savage MO, Clark AJ, Camacho-Hübner C.

Horm Res Paediatr. 2010;73(5):328-34. doi: 10.1159/000308164. Epub 2010 Apr 14.


Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.

Taussig DC, Vargaftig J, Miraki-Moud F, Griessinger E, Sharrock K, Luke T, Lillington D, Oakervee H, Cavenagh J, Agrawal SG, Lister TA, Gribben JG, Bonnet D.

Blood. 2010 Mar 11;115(10):1976-84. doi: 10.1182/blood-2009-02-206565. Epub 2010 Jan 6.


Identification and characterisation of a novel GHR defect disrupting the polypyrimidine tract and resulting in GH insensitivity.

David A, Miraki-Moud F, Shaw NJ, Savage MO, Clark AJ, Metherell LA.

Eur J Endocrinol. 2010 Jan;162(1):37-42. doi: 10.1530/EJE-09-0583. Epub 2009 Oct 7.


Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts.

Le Dieu R, Taussig DC, Ramsay AG, Mitter R, Miraki-Moud F, Fatah R, Lee AM, Lister TA, Gribben JG.

Blood. 2009 Oct 29;114(18):3909-16. doi: 10.1182/blood-2009-02-206946. Epub 2009 Aug 26.


Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells.

Taussig DC, Miraki-Moud F, Anjos-Afonso F, Pearce DJ, Allen K, Ridler C, Lillington D, Oakervee H, Cavenagh J, Agrawal SG, Lister TA, Gribben JG, Bonnet D.

Blood. 2008 Aug 1;112(3):568-75. doi: 10.1182/blood-2007-10-118331. Epub 2008 Jun 3.


An intronic growth hormone receptor mutation causing activation of a pseudoexon is associated with a broad spectrum of growth hormone insensitivity phenotypes.

David A, Camacho-Hübner C, Bhangoo A, Rose SJ, Miraki-Moud F, Akker SA, Butler GE, Ten S, Clayton PE, Clark AJ, Savage MO, Metherell LA.

J Clin Endocrinol Metab. 2007 Feb;92(2):655-9. Epub 2006 Dec 5.


Final height in patients with idiopathic short stature and high growth hormone responses to stimulation tests.

Martinelli CE, Sader Milani S, Previato JK, Figueira M, Rangel Montenegro AP, Miraki-Moud F, Betancourth S, Moreira AC, Savage MO, Camacho-Hübner C.

Horm Res. 2007;67(5):224-30. Epub 2006 Nov 28.


Dehydroepiandrosterone (DHEA) replacement reduces growth hormone (GH) dose requirement in female hypopituitary patients on GH replacement.

Brooke AM, Kalingag LA, Miraki-Moud F, Camacho-Hübner C, Maher KT, Walker DM, Hinson JP, Monson JP.

Clin Endocrinol (Oxf). 2006 Nov;65(5):673-80.


Dehydroepiandrosterone improves psychological well-being in male and female hypopituitary patients on maintenance growth hormone replacement.

Brooke AM, Kalingag LA, Miraki-Moud F, Camacho-Hübner C, Maher KT, Walker DM, Hinson JP, Monson JP.

J Clin Endocrinol Metab. 2006 Oct;91(10):3773-9. Epub 2006 Jul 18.


Pharmacokinetic studies of recombinant human insulin-like growth factor I (rhIGF-I)/rhIGF-binding protein-3 complex administered to patients with growth hormone insensitivity syndrome.

Camacho-Hübner C, Rose S, Preece MA, Sleevi M, Storr HL, Miraki-Moud F, Minuto F, Frystyk J, Rogol A, Allan G, Sommer A, Savage MO.

J Clin Endocrinol Metab. 2006 Apr;91(4):1246-53. Epub 2006 Jan 10.


A rapid method for analyzing serum pro-insulin-like growth factor-II in patients with non-islet cell tumor hypoglycemia.

Miraki-Moud F, Grossman AB, Besser M, Monson JP, Camacho-Hübner C.

J Clin Endocrinol Metab. 2005 Jul;90(7):3819-23. Epub 2005 Apr 19.


Pseudo-precocious puberty caused by a juvenile granulosa cell tumour secreting androstenedione, inhibin and insulin-like growth factor-I.

Chan LF, Storr HL, Scheimberg I, Perry LA, Banerjee K, Miraki-Moud F, Camacho-Hübner C, Savage MO.

J Pediatr Endocrinol Metab. 2004 Apr;17(4):679-84.


Standard and low-dose IGF-I generation tests and spontaneous growth hormone secretion in children with idiopathic short stature.

Blair JC, Camacho-Hübner C, Miraki Moud F, Rosberg S, Burren C, Lim S, Clayton PE, Bjarnason R, Albertsson-Wikland K, Savage MO.

Clin Endocrinol (Oxf). 2004 Feb;60(2):163-8; discussion 161-2.


Interleukin-1beta (IL-1beta) and IL-6 modulate insulin-like growth factor-binding protein (IGFBP) secretion in colon cancer epithelial (Caco-2) cells.

Street ME, Miraki-Moud F, Sanderson IR, Savage MO, Giovannelli G, Bernasconi S, Camacho-Hübner C.

J Endocrinol. 2003 Dec;179(3):405-15.


Growth hormone therapy for non-islet cell tumor hypoglycemia.

Silveira LF, Bouloux PM, MacColl GS, Camacho-Hubner C, Miraki-Moud F.

Am J Med. 2002 Aug 15;113(3):255-7. No abstract available.


Increased levels of insulin-like growth factor binding protein-2 in sera and tumours from patients with colonic neoplasia with and without acromegaly.

Miraki-Moud F, Jenkins PJ, Fairclough PD, Jordan S, Bustin SA, Jones AM, Lowe DG, Monson JP, Grossman AB, Besser GM, Camacho-Hübner C.

Clin Endocrinol (Oxf). 2001 Apr;54(4):499-508.


Effect of severe growth hormone (GH) deficiency due to a mutation in the GH-releasing hormone receptor on insulin-like growth factors (IGFs), IGF-binding proteins, and ternary complex formation throughout life.

Aguiar-Oliveira MH, Gill MS, de A Barretto ES, Alcântara MR, Miraki-Moud F, Menezes CA, Souza AH, Martinelli CE, Pereira FA, Salvatori R, Levine MA, Shalet SM, Camacho-Hubner C, Clayton PE.

J Clin Endocrinol Metab. 1999 Nov;84(11):4118-26.


Insulin-like growth factor-I deficiency caused by a partial deletion of the IGF-I gene: effects of rhIGF-I therapy.

Camacho-Hübner C, Woods KA, Miraki-Moud F, Clark A, Savage MO.

Growth Horm IGF Res. 1999 Jun;9 Suppl B:47-51; discussion 51-2.


Effects of recombinant human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion.

Camacho-Hübner C, Woods KA, Miraki-Moud F, Hindmarsh PC, Clark AJ, Hansson Y, Johnston A, Baxter RC, Savage MO.

J Clin Endocrinol Metab. 1999 May;84(5):1611-6.


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