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Items: 1 to 50 of 59

1.

Dissecting the role of thyrotropin in the DNA damage response in human thyrocytes after 131I, γ radiation and H2O2.

Kyrilli A, Gacquer D, Detours V, Lefort A, Libert F, Twyffels L, Van den Eeckhaute L, Strickaert A, Maenhaut C, De Deken X, Dumont JE, Miot F, Corvilain B.

J Clin Endocrinol Metab. 2019 Nov 8. pii: dgz185. doi: 10.1210/clinem/dgz185. [Epub ahead of print]

PMID:
31701151
2.

The Dual Oxidase Duox2 stabilized with DuoxA2 in an enzymatic complex at the surface of the cell produces extracellular H2O2 able to induce DNA damage in an inducible cellular model.

Poncelet L, Dumont JE, Miot F, De Deken X.

Exp Cell Res. 2019 Nov 1;384(1):111620. doi: 10.1016/j.yexcr.2019.111620. Epub 2019 Sep 9.

PMID:
31513783
3.

DUOX Defects and Their Roles in Congenital Hypothyroidism.

De Deken X, Miot F.

Methods Mol Biol. 2019;1982:667-693. doi: 10.1007/978-1-4939-9424-3_37.

PMID:
31172499
4.

Expression, Localization, and Regulation of the Sodium Bicarbonate Cotransporter NBCe1 in the Thyroid.

Virreira M, Jin L, Djerbib S, De Deken X, Miot F, Massart C, Svoboda M, Van Sande J, Beauwens R, Dumont JE, Boom A.

Thyroid. 2019 Feb;29(2):290-301. doi: 10.1089/thy.2017.0576. Epub 2019 Jan 23.

PMID:
30526387
5.

Factors contributing to the resistance of the thyrocyte to hydrogen peroxide.

Ghaddhab C, Kyrilli A, Driessens N, Van Den Eeckhaute E, Hancisse O, De Deken X, Dumont JE, Detours V, Miot F, Corvilain B.

Mol Cell Endocrinol. 2019 Feb 5;481:62-70. doi: 10.1016/j.mce.2018.11.010. Epub 2018 Nov 23.

PMID:
30476559
6.

Commentary: Thyrotropin Stimulates Differentiation Not Proliferation of Normal Human Thyrocytes in Culture.

Kyrilli A, Paternot S, Miot F, Corvilain B, Vassart G, Roger PP, Dumont JE.

Front Endocrinol (Lausanne). 2017 Aug 25;8:214. doi: 10.3389/fendo.2017.00214. eCollection 2017. No abstract available.

7.

Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin.

Eskalli Z, Achouri Y, Hahn S, Many MC, Craps J, Refetoff S, Liao XH, Dumont JE, Van Sande J, Corvilain B, Miot F, De Deken X.

Thyroid. 2016 Oct;26(10):1499-1512.

8.

Chapter 2 Thyroid Hormone Synthesis And Secretion.

Rousset B, Dupuy C, Miot F, Dumont J.

In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
2015 Sep 2.

9.

NADPH oxidase DUOX1 promotes long-term persistence of oxidative stress after an exposure to irradiation.

Ameziane-El-Hassani R, Talbot M, de Souza Dos Santos MC, Al Ghuzlan A, Hartl D, Bidart JM, De Deken X, Miot F, Diallo I, de Vathaire F, Schlumberger M, Dupuy C.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5051-6. doi: 10.1073/pnas.1420707112. Epub 2015 Apr 6.

10.

Diphenyleneiodonium, an inhibitor of NOXes and DUOXes, is also an iodide-specific transporter.

Massart C, Giusti N, Beauwens R, Dumont JE, Miot F, Sande JV.

FEBS Open Bio. 2013 Dec 7;4:55-9. doi: 10.1016/j.fob.2013.11.007. eCollection 2013.

11.

Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.

De Deken X, Corvilain B, Dumont JE, Miot F.

Antioxid Redox Signal. 2014 Jun 10;20(17):2776-93. doi: 10.1089/ars.2013.5602. Epub 2013 Oct 25. Review.

PMID:
24161126
12.

Comparative analysis of the thyrocytes and T cells: responses to H2O2 and radiation reveals an H2O2-induced antioxidant transcriptional program in thyrocytes.

Versteyhe S, Driessens N, Ghaddhab C, Tarabichi M, Hoste C, Dumont JE, Miot F, Corvilain B, Detours V.

J Clin Endocrinol Metab. 2013 Oct;98(10):E1645-54. doi: 10.1210/jc.2013-1266. Epub 2013 May 10.

PMID:
23666977
13.

IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response.

Fink K, Martin L, Mukawera E, Chartier S, De Deken X, Brochiero E, Miot F, Grandvaux N.

Cell Res. 2013 May;23(5):673-90. doi: 10.1038/cr.2013.47. Epub 2013 Apr 2. Erratum in: Cell Res. 2014 Apr;24(4):509.

14.

Stroma cell-derived factor-1α signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes.

Hadad I, Veithen A, Springael JY, Sotiropoulou PA, Mendes Da Costa A, Miot F, Naeije R, De Deken X, Entee KM.

PLoS One. 2013;8(2):e56007. doi: 10.1371/journal.pone.0056007. Epub 2013 Feb 27.

15.

Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2 and its maturation factor DUOXA2.

Raad H, Eskalli Z, Corvilain B, Miot F, De Deken X.

Free Radic Biol Med. 2013 Mar;56:216-25. doi: 10.1016/j.freeradbiomed.2012.09.003. Epub 2012 Sep 23.

PMID:
23010498
16.

The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.

Hoste C, Dumont JE, Miot F, De Deken X.

Exp Cell Res. 2012 Nov 1;318(18):2353-64. doi: 10.1016/j.yexcr.2012.07.007. Epub 2012 Jul 16.

PMID:
22814254
17.

Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.

Damiano S, Fusco R, Morano A, De Mizio M, Paternò R, De Rosa A, Spinelli R, Amente S, Frunzio R, Mondola P, Miot F, Laccetti P, Santillo M, Avvedimento EV.

PLoS One. 2012;7(4):e34405. doi: 10.1371/journal.pone.0034405. Epub 2012 Apr 16.

18.

The nonphagocytic NADPH oxidase Duox1 mediates a positive feedback loop during T cell receptor signaling.

Kwon J, Shatynski KE, Chen H, Morand S, de Deken X, Miot F, Leto TL, Williams MS.

Sci Signal. 2010 Aug 3;3(133):ra59. doi: 10.1126/scisignal.2000976.

19.
20.

H2O2, signal, substrate, mutagen and chemorepellent from physiology to biochemistry and disease.

Dumont JE, De Deken X, Miot F, Corvilain V, Contempré B, Goyens R, Massart C, Van Sande J, Allaoui A, Botteaux A.

Bull Mem Acad R Med Belg. 2010;165(5-6):231-4; discussion 235.

PMID:
21510483
21.

Hydrogen peroxide induces DNA single- and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ.

Driessens N, Versteyhe S, Ghaddhab C, Burniat A, De Deken X, Van Sande J, Dumont JE, Miot F, Corvilain B.

Endocr Relat Cancer. 2009 Sep;16(3):845-56. doi: 10.1677/ERC-09-0020. Epub 2009 Jun 9.

PMID:
19509065
22.

Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.

Rigutto S, Hoste C, Grasberger H, Milenkovic M, Communi D, Dumont JE, Corvilain B, Miot F, De Deken X.

J Biol Chem. 2009 Mar 13;284(11):6725-34. doi: 10.1074/jbc.M806893200. Epub 2009 Jan 14.

23.

Human thyroid tumours, the puzzling lessons from E7 and RET/PTC3 transgenic mice.

Jin L, Burniat A, Dumont JE, Miot F, Corvilain B, Franc B.

Br J Cancer. 2008 Dec 2;99(11):1874-83. doi: 10.1038/sj.bjc.6604740. Epub 2008 Nov 4. Erratum in: Br J Cancer. 2009 Mar 24;100(6):1013.

24.

Gene expression in RET/PTC3 and E7 transgenic mouse thyroids: RET/PTC3 but not E7 tumors are partial and transient models of human papillary thyroid cancers.

Burniat A, Jin L, Detours V, Driessens N, Goffard JC, Santoro M, Rothstein J, Dumont JE, Miot F, Corvilain B.

Endocrinology. 2008 Oct;149(10):5107-17. doi: 10.1210/en.2008-0531. Epub 2008 Jun 26.

PMID:
18583418
25.

Roles of hydrogen peroxide in thyroid physiology and disease.

Song Y, Driessens N, Costa M, De Deken X, Detours V, Corvilain B, Maenhaut C, Miot F, Van Sande J, Many MC, Dumont JE.

J Clin Endocrinol Metab. 2007 Oct;92(10):3764-73. Epub 2007 Jul 31. Review.

PMID:
17666482
26.

Duox1 is the main source of hydrogen peroxide in the rat thyroid cell line PCCl3.

Rigutto S, Hoste C, Dumont JE, Corvilain B, Miot F, De Deken X.

Exp Cell Res. 2007 Nov 1;313(18):3892-901. Epub 2007 Jun 29.

PMID:
17643428
27.

Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor.

Grasberger H, De Deken X, Miot F, Pohlenz J, Refetoff S.

Mol Endocrinol. 2007 Jun;21(6):1408-21. Epub 2007 Mar 20.

PMID:
17374849
28.

Developmental regulation of DUOX1 expression and function in human fetal lung epithelial cells.

Fischer H, Gonzales LK, Kolla V, Schwarzer C, Miot F, Illek B, Ballard PL.

Am J Physiol Lung Cell Mol Physiol. 2007 Jun;292(6):L1506-14. Epub 2007 Mar 2.

29.

Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.

Milenkovic M, De Deken X, Jin L, De Felice M, Di Lauro R, Dumont JE, Corvilain B, Miot F.

J Endocrinol. 2007 Mar;192(3):615-26.

PMID:
17332529
30.

Regulation of H2O2 generation in thyroid cells does not involve Rac1 activation.

Fortemaison N, Miot F, Dumont JE, Dremier S.

Eur J Endocrinol. 2005 Jan;152(1):127-33.

PMID:
15762196
31.

Regulated hydrogen peroxide production by Duox in human airway epithelial cells.

Forteza R, Salathe M, Miot F, Forteza R, Conner GE.

Am J Respir Cell Mol Biol. 2005 May;32(5):462-9. Epub 2005 Jan 27.

PMID:
15677770
32.

Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.

Wang D, De Deken X, Milenkovic M, Song Y, Pirson I, Dumont JE, Miot F.

J Biol Chem. 2005 Jan 28;280(4):3096-103. Epub 2004 Nov 22.

33.

Structural and functional characterization of the two human ThOX/Duox genes and their 5'-flanking regions.

Pachucki J, Wang D, Christophe D, Miot F.

Mol Cell Endocrinol. 2004 Feb 12;214(1-2):53-62.

PMID:
15062544
34.

Correlation between the loss of thyroglobulin iodination and the expression of thyroid-specific proteins involved in iodine metabolism in thyroid carcinomas.

Gérard AC, Daumerie C, Mestdagh C, Gohy S, De Burbure C, Costagliola S, Miot F, Nollevaux MC, Denef JF, Rahier J, Franc B, De Vijlder JJ, Colin IM, Many MC.

J Clin Endocrinol Metab. 2003 Oct;88(10):4977-83.

PMID:
14557483
35.
36.

Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.

De Deken X, Wang D, Dumont JE, Miot F.

Exp Cell Res. 2002 Feb 15;273(2):187-96.

PMID:
11822874
37.

Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.

De Deken X, Wang D, Many MC, Costagliola S, Libert F, Vassart G, Dumont JE, Miot F.

J Biol Chem. 2000 Jul 28;275(30):23227-33.

38.

Loss of several cell functions including okadaic acid-induced apoptosis after multiple passages in FRTL-5 cells.

Golstein J, Kimura T, Miot F, Dumont JE.

Mol Cell Endocrinol. 1999 Apr 25;150(1-2):141-9.

PMID:
10411308
40.

Decrease of telomere length in thyroid adenomas without telomerase activity.

De Deken X, Vilain C, Van Sande J, Dumont JE, Miot F.

J Clin Endocrinol Metab. 1998 Dec;83(12):4368-72.

PMID:
9851779
41.

A new tool for efficient transfection of dog and human thyrocytes in primary culture.

Uyttersprot N, Costagliola S, Miot F.

Mol Cell Endocrinol. 1998 Jul 25;142(1-2):35-9.

PMID:
9783900
42.

Moderate doses of iodide in vivo inhibit cell proliferation and the expression of thyroperoxidase and Na+/I- symporter mRNAs in dog thyroid.

Uyttersprot N, Pelgrims N, Carrasco N, Gervy C, Maenhaut C, Dumont JE, Miot F.

Mol Cell Endocrinol. 1997 Aug 8;131(2):195-203.

PMID:
9296378
43.

Dog CREM transcription factors: cloning, tissue distribution, and identification of new isoforms.

Uyttersprot N, Miot F.

Biochem Biophys Res Commun. 1997 Aug 8;237(1):74-8.

PMID:
9266832
44.

Pitfalls in the use of several "housekeeping" genes as standards for quantitation of mRNA: the example of thyroid cells.

Savonet V, Maenhaut C, Miot F, Pirson I.

Anal Biochem. 1997 Apr 5;247(1):165-7. No abstract available.

PMID:
9126387
45.

The cAMP in thyroid: from the TSH receptor to mitogenesis and tumorigenesis.

Uyttersprot N, Allgeier A, Baptist M, Christophe D, Coppee F, Coulonval K, Deleu S, Depoortere F, Dremier S, Lamy F, Ledent C, Maenhaut C, Miot F, Panneels V, Parma J, Parmentier M, Pirson I, Pohl V, Roger P, Savonet V, Taton M, Tonacchera M, van Sande J, Wilkin F, Vassart G, et al.

Adv Second Messenger Phosphoprotein Res. 1997;31:125-40. Review. No abstract available.

PMID:
9344247
46.

Cloning of cDNA specifically involved in the thyroid cAMP mitogenic pathway.

Miot F, Wilkin F, Dremier S, Uyttersprot N, Lamy F, Dumont JE, Maenhaut C.

Horm Res. 1994;42(1-2):27-30. Review.

PMID:
7959630
47.
48.

Excitation characteristics of adiabatic half-passage RF pulses used in surface coil MR spectroscopy. Application to 13C detection of glycogen in the rat liver.

Van Cauteren M, Miot F, Segebarth CM, Eisendrath H, Osteaux M, Willem R.

Phys Med Biol. 1992 May;37(5):1055-64.

PMID:
1608995
49.

Lack of V1 vasopressin receptors in rabbit hepatocytes.

Vandekerckhove A, Miot F, Keppens S, De Wulf H.

Biochem J. 1989 Apr 15;259(2):609-11.

50.

Involvement of a plasma membrane phosphodiesterase in the negative control of cyclic AMP levels by vasopressin in rat hepatocytes.

Miot F, Keppens S, Erneux C, Wells JN, De Wulf H.

Biochem Pharmacol. 1988 Sep 15;37(18):3447-53.

PMID:
2844189

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