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Items: 1 to 50 of 145

1.

β-Caryophyllene Mitigates Collagen Antibody Induced Arthritis (CAIA) in Mice Through a Cross-Talk between CB2 and PPAR-γ Receptors.

Irrera N, D'Ascola A, Pallio G, Bitto A, Mazzon E, Mannino F, Squadrito V, Arcoraci V, Minutoli L, Campo GM, Avenoso A, Bongiorno EB, Vaccaro M, Squadrito F, Altavilla D.

Biomolecules. 2019 Jul 31;9(8). pii: E326. doi: 10.3390/biom9080326.

2.

Myo-inositol in the protection from cadmium-induced toxicity in mice kidney: An emerging nutraceutical challenge.

Pallio G, Micali A, Benvenga S, Antonelli A, Marini HR, Puzzolo D, Macaione V, Trichilo V, Santoro G, Irrera N, Squadrito F, Altavilla D, Minutoli L.

Food Chem Toxicol. 2019 Jul 12;132:110675. doi: 10.1016/j.fct.2019.110675. [Epub ahead of print]

PMID:
31306689
3.

Effects of Myo-inositol Alone and in Combination with Seleno-L-methionine on Cadmium-Induced Testicular Damage in Mice.

Benvenga S, Micali A, Pallio G, Vita R, Malta C, Puzzolo D, Irrera N, Squadrito F, Altavilla D, Minutoli L.

Curr Mol Pharmacol. 2019 Jun 20. doi: 10.2174/1874467212666190620143303. [Epub ahead of print]

PMID:
31250768
4.

Post-Mortem Immunohistochemical Evidence of β2-Adrenergic Receptor Expression in the Adrenal Gland.

Ventura Spagnolo E, Mondello C, Cardia L, Minutoli L, Puzzolo D, Asmundo A, Macaione V, Alibrandi A, Malta C, Baldino G, Micali A.

Int J Mol Sci. 2019 Jun 23;20(12). pii: E3065. doi: 10.3390/ijms20123065.

5.

Medical simulation in pharmacology learning and retention: A comparison study with traditional teaching in undergraduate medical students.

Arcoraci V, Squadrito F, Altavilla D, Bitto A, Minutoli L, Penna O, Amato A, Bruno R, Tripodi VF, Alibrandi A, Ingrassia PL, Santalucia P, Fodale V.

Pharmacol Res Perspect. 2019 Jan 9;7(1):e00449. doi: 10.1002/prp2.449. eCollection 2019 Feb.

6.

Corrigendum to "Neuroprotective Effects of Polydeoxyribonucleotide in a Murine Model of Cadmium Toxicity".

Marini HR, Puzzolo D, Micali A, Adamo EB, Irrera N, Pisani A, Pallio G, Trichilo V, Malta C, Squadrito F, Altavilla D, Minutoli L.

Oxid Med Cell Longev. 2018 Dec 13;2018:9176012. doi: 10.1155/2018/9176012. eCollection 2018.

7.

Neuroprotective Effects of Polydeoxyribonucleotide in a Murine Model of Cadmium Toxicity.

Marini HR, Puzzolo D, Micali A, Adamo EB, Irrera N, Pisani A, Pallio G, Trichilo V, Malta C, Bitto A, Squadrito F, Altavilla D, Minutoli L.

Oxid Med Cell Longev. 2018 Aug 29;2018:4285694. doi: 10.1155/2018/4285694. eCollection 2018. Erratum in: Oxid Med Cell Longev. 2018 Dec 13;2018:9176012.

8.

Activation of A2A Receptor by PDRN Reduces Neuronal Damage and Stimulates WNT/β-CATENIN Driven Neurogenesis in Spinal Cord Injury.

Irrera N, Arcoraci V, Mannino F, Vermiglio G, Pallio G, Minutoli L, Bagnato G, Anastasi GP, Mazzon E, Bramanti P, Squadrito F, Altavilla D, Bitto A.

Front Pharmacol. 2018 May 29;9:506. doi: 10.3389/fphar.2018.00506. eCollection 2018.

9.

Flavocoxid, a Natural Antioxidant, Protects Mouse Kidney from Cadmium-Induced Toxicity.

Micali A, Pallio G, Irrera N, Marini H, Trichilo V, Puzzolo D, Pisani A, Malta C, Santoro G, Laurà R, Santoro D, Squadrito F, Altavilla D, Germanà A, Minutoli L.

Oxid Med Cell Longev. 2018 Apr 18;2018:9162946. doi: 10.1155/2018/9162946. eCollection 2018.

10.

Cadmium-Induced Oxidative Stress Impairs Glycemic Control in Adolescents.

Pizzino G, Irrera N, Bitto A, Pallio G, Mannino F, Arcoraci V, Aliquò F, Minutoli L, De Ponte C, D'andrea P, Squadrito F, Altavilla D.

Oxid Med Cell Longev. 2017;2017:6341671. doi: 10.1155/2017/6341671. Epub 2017 Dec 12.

11.

Activation of the EPOR-β common receptor complex by cibinetide ameliorates impaired wound healing in mice with genetic diabetes.

Bitto A, Irrera N, Pizzino G, Pallio G, Mannino F, Vaccaro M, Arcoraci V, Aliquò F, Minutoli L, Colonna MR, Galeano MR, Brines M, De Ponte C, Collino M, Squadrito F, Altavilla D.

Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):632-639. doi: 10.1016/j.bbadis.2017.12.006. Epub 2017 Dec 7.

12.

Flavocoxid exerts a potent antiviral effect against hepatitis B virus.

Pollicino T, Musolino C, Irrera N, Bitto A, Lombardo D, Timmoneri M, Minutoli L, Raimondo G, Squadrito G, Squadrito F, Altavilla D.

Inflamm Res. 2018 Jan;67(1):89-103. doi: 10.1007/s00011-017-1099-2. Epub 2017 Oct 10.

PMID:
29018874
13.

Modulation of Dkk-3 and claudin-5 as new therapeutic strategy in the treatment of meningiomas.

Caffo M, Esposito E, Barresi V, Caruso G, Cardali SM, Rinaldi M, Mallamace R, Campolo M, Casili G, Conti A, Germanò A, Cuzzocrea S, Minutoli L.

Oncotarget. 2017 Aug 7;8(40):68280-68290. doi: 10.18632/oncotarget.20047. eCollection 2017 Sep 15.

14.

Lack of the Nlrp3 Inflammasome Improves Mice Recovery Following Traumatic Brain Injury.

Irrera N, Pizzino G, Calò M, Pallio G, Mannino F, Famà F, Arcoraci V, Fodale V, David A, Francesca C, Minutoli L, Mazzon E, Bramanti P, Squadrito F, Altavilla D, Bitto A.

Front Pharmacol. 2017 Jul 14;8:459. doi: 10.3389/fphar.2017.00459. eCollection 2017.

15.

Cadmium, Organ Toxicity and Therapeutic Approaches: A Review on Brain, Kidney and Testis Damage.

Rinaldi M, Micali A, Marini H, Adamo EB, Puzzolo D, Pisani A, Trichilo V, Altavilla D, Squadrito F, Minutoli L.

Curr Med Chem. 2017 Nov 20;24(35):3879-3893. doi: 10.2174/0929867324666170801101448. Review.

PMID:
28762312
16.

Pharmacological Activity and Clinical Use of PDRN.

Squadrito F, Bitto A, Irrera N, Pizzino G, Pallio G, Minutoli L, Altavilla D.

Front Pharmacol. 2017 Apr 26;8:224. doi: 10.3389/fphar.2017.00224. eCollection 2017. Review.

17.

Survivin and NAIP in Human Benign Prostatic Hyperplasia: Protective Role of the Association of Serenoa repens, Lycopene and Selenium from the Randomized Clinical Study.

Morgia G, Micali A, Rinaldi M, Irrera N, Marini H, Puzzolo D, Pisani A, Privitera S, Russo GI, Cimino S, Ieni A, Trichilo V, Altavilla D, Squadrito F, Minutoli L.

Int J Mol Sci. 2017 Mar 22;18(3). pii: E680. doi: 10.3390/ijms18030680.

18.

Antiosteoporotic Activity of Genistein Aglycone in Postmenopausal Women: Evidence from a Post-Hoc Analysis of a Multicenter Randomized Controlled Trial.

Arcoraci V, Atteritano M, Squadrito F, D'Anna R, Marini H, Santoro D, Minutoli L, Messina S, Altavilla D, Bitto A.

Nutrients. 2017 Feb 22;9(2). pii: E179. doi: 10.3390/nu9020179.

19.

Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice.

Bitto A, Giuliani D, Pallio G, Irrera N, Vandini E, Canalini F, Zaffe D, Ottani A, Minutoli L, Rinaldi M, Guarini S, Squadrito F, Altavilla D.

Inflamm Res. 2017 May;66(5):389-398. doi: 10.1007/s00011-017-1022-x. Epub 2017 Feb 25.

PMID:
28238167
20.

Polydeoxyribonucleotide, an Adenosine-A2A Receptor Agonist, Preserves Blood Testis Barrier from Cadmium-Induced Injury.

Squadrito F, Micali A, Rinaldi M, Irrera N, Marini H, Puzzolo D, Pisani A, Lorenzini C, Valenti A, Laurà R, Germanà A, Bitto A, Pizzino G, Pallio G, Altavilla D, Minutoli L.

Front Pharmacol. 2017 Jan 10;7:537. doi: 10.3389/fphar.2016.00537. eCollection 2016.

21.

BAY 11-7082 inhibits the NF-κB and NLRP3 inflammasome pathways and protects against IMQ-induced psoriasis.

Irrera N, Vaccaro M, Bitto A, Pallio G, Pizzino G, Lentini M, Arcoraci V, Minutoli L, Scuruchi M, Cutroneo G, Anastasi GP, Ettari R, Squadrito F, Altavilla D.

Clin Sci (Lond). 2017 Mar 1;131(6):487-498. doi: 10.1042/CS20160645. Epub 2017 Jan 17.

PMID:
28096316
22.

Apoptotic Pathways Linked to Endocrine System as Potential Therapeutic Targets for Benign Prostatic Hyperplasia.

Minutoli L, Rinaldi M, Marini H, Irrera N, Crea G, Lorenzini C, Puzzolo D, Valenti A, Pisani A, Adamo EB, Altavilla D, Squadrito F, Micali A.

Int J Mol Sci. 2016 Aug 11;17(8). pii: E1311. doi: 10.3390/ijms17081311. Review.

23.

Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.

Pallio G, Bitto A, Pizzino G, Galfo F, Irrera N, Minutoli L, Arcoraci V, Squadrito G, Macrì A, Squadrito F, Altavilla D.

Eur J Pharmacol. 2016 Oct 15;789:152-162. doi: 10.1016/j.ejphar.2016.07.033. Epub 2016 Jul 21.

PMID:
27450484
24.

ROS and Brain Gliomas: An Overview of Potential and Innovative Therapeutic Strategies.

Rinaldi M, Caffo M, Minutoli L, Marini H, Abbritti RV, Squadrito F, Trichilo V, Valenti A, Barresi V, Altavilla D, Passalacqua M, Caruso G.

Int J Mol Sci. 2016 Jun 22;17(6). pii: E984. doi: 10.3390/ijms17060984. Review.

25.

ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury.

Minutoli L, Puzzolo D, Rinaldi M, Irrera N, Marini H, Arcoraci V, Bitto A, Crea G, Pisani A, Squadrito F, Trichilo V, Bruschetta D, Micali A, Altavilla D.

Oxid Med Cell Longev. 2016;2016:2183026. doi: 10.1155/2016/2183026. Epub 2016 Apr 5. Review.

26.

Visfatin correlates with hot flashes in postmenopausal women with metabolic syndrome: effects of genistein.

Bitto A, Arcoraci V, Alibrandi A, D'Anna R, Corrado F, Atteritano M, Minutoli L, Altavilla D, Squadrito F.

Endocrine. 2017 Mar;55(3):899-906. doi: 10.1007/s12020-016-0968-8. Epub 2016 Apr 28.

PMID:
27126198
27.

Simvastatin prevents vascular complications in the chronic reactive oxygen species murine model of systemic sclerosis.

Bitto A, Bagnato GL, Pizzino G, Roberts WN, Irrera N, Minutoli L, Russo G, Squadrito F, Saitta A, Bagnato GF, Altavilla D.

Free Radic Res. 2016;50(5):514-22. doi: 10.3109/10715762.2016.1149171. Epub 2016 Mar 17.

PMID:
26846205
28.

Erratum: Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood-Testis Barrier and Improves Testicular Damage and Germ Cell Impairment in Mice.

Minutoli L, Micali A, Pisani A, Puzzolo D, Bitto A, Rinaldi M, Pizzino G, Irrera N, Galfo F, Arena S, Pallio G, Mecchio A, Germanà A, Bruschetta D, Laurà R, Magno C, Marini H, Squadrito F, Altavilla D.

Toxicol Sci. 2016 Jan;149(1):270. doi: 10.1093/toxsci/kfv247. Epub 2015 Dec 3. No abstract available.

PMID:
26637550
29.

Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood–Testis Barrier and Improves Testicular Damage and Germ Cell Impairment in Mice [corrected].

Minutoli L, Micali A, Pisani A, Puzzolo D, Bitto A, Rinaldi M, Pizzino G, Irrera N, Galfo F, Arena S, Pallio G, Mecchio A, Germanà A, Bruschetta D, Laurà R, Magno C, Marini H, Squadrito F, Altavilla D.

Toxicol Sci. 2015 Nov;148(1):311-29. doi: 10.1093/toxsci/kfv185. Epub 2015 Sep 30. Erratum in: Toxicol Sci. 2015 Dec 3;149(1):270.

PMID:
26424772
30.

NLRP3 Inflammasome Involvement in the Organ Damage and Impaired Spermatogenesis Induced by Testicular Ischemia and Reperfusion in Mice.

Minutoli L, Antonuccio P, Irrera N, Rinaldi M, Bitto A, Marini H, Pizzino G, Romeo C, Pisani A, Santoro G, Puzzolo D, Magno C, Squadrito F, Micali A, Altavilla D.

J Pharmacol Exp Ther. 2015 Dec;355(3):370-80. doi: 10.1124/jpet.115.226936. Epub 2015 Sep 25.

PMID:
26407722
31.

Role of Inhibitors of Apoptosis Proteins in Testicular Function and Male Fertility: Effects of Polydeoxyribonucleotide Administration in Experimental Varicocele.

Minutoli L, Arena S, Antonuccio P, Romeo C, Bitto A, Magno C, Rinaldi M, Micali A, Irrera N, Pizzino G, Galfo F, Squadrito F, Altavilla D, Marini H.

Biomed Res Int. 2015;2015:248976. doi: 10.1155/2015/248976. Epub 2015 Aug 4.

32.

Modulation of neuronal nitric oxide synthase and apoptosis by the isoflavone genistein in Mdx mice.

Messina S, Bitto A, Vita GL, Aguennouz M, Irrera N, Licata N, Sframeli M, Bruschetta D, Minutoli L, Altavilla D, Vita G, Squadrito F.

Biofactors. 2015 Sep-Oct;41(5):324-9. doi: 10.1002/biof.1226. Epub 2015 Aug 31.

PMID:
26332024
33.

Epoetin Alpha and Epoetin Zeta: A Comparative Study on Stimulation of Angiogenesis and Wound Repair in an Experimental Model of Burn Injury.

Irrera N, Bitto A, Pizzino G, Vaccaro M, Squadrito F, Galeano M, Stagno d'Alcontres F, Stagno d'Alcontres F, Buemi M, Minutoli L, Colonna MR, Altavilla D.

Biomed Res Int. 2015;2015:968927. doi: 10.1155/2015/968927. Epub 2015 Jun 4.

34.

A dual inhibitor of cyclooxygenase and 5-lipoxygenase protects against kainic acid-induced brain injury.

Minutoli L, Marini H, Rinaldi M, Bitto A, Irrera N, Pizzino G, Pallio G, Calò M, Adamo EB, Trichilo V, Interdonato M, Galfo F, Squadrito F, Altavilla D.

Neuromolecular Med. 2015 Jun;17(2):192-201. doi: 10.1007/s12017-015-8351-0. Epub 2015 Apr 19.

PMID:
25893744
35.

Blockade of the JNK signalling as a rational therapeutic approach to modulate the early and late steps of the inflammatory cascade in polymicrobial sepsis.

Pizzino G, Bitto A, Pallio G, Irrera N, Galfo F, Interdonato M, Mecchio A, De Luca F, Minutoli L, Squadrito F, Altavilla D.

Mediators Inflamm. 2015;2015:591572. doi: 10.1155/2015/591572. Epub 2015 Mar 22.

36.

CO2 pneumoperitoneum preserves β-arrestin 2 content and reduces high mobility group box-1 (HMGB-1) expression in an animal model of peritonitis.

Montalto AS, Bitto A, Minutoli L, Impellizzeri P, Costa G, Irrera N, Pizzino G, Squadrito F, Altavilla D, Romeo C.

Oxid Med Cell Longev. 2015;2015:160568. doi: 10.1155/2015/160568. Epub 2015 Feb 24.

37.

Cadmium delays puberty onset and testis growth in adolescents.

Interdonato M, Pizzino G, Bitto A, Galfo F, Irrera N, Mecchio A, Pallio G, Ramistella V, De Luca F, Santamaria A, Minutoli L, Marini H, Squadrito F, Altavilla D.

Clin Endocrinol (Oxf). 2015 Sep;83(3):357-62. doi: 10.1111/cen.12704. Epub 2015 Jan 15.

PMID:
25521350
38.

Levels of heavy metals in adolescents living in the industrialised area of Milazzo-Valle del Mela (northern Sicily).

Interdonato M, Bitto A, Pizzino G, Irrera N, Pallio G, Mecchio A, Cuspilici A, Minutoli L, Altavilla D, Squadrito F.

J Environ Public Health. 2014;2014:326845. doi: 10.1155/2014/326845. Epub 2014 Sep 23.

39.

Oxidative stress and DNA repair and detoxification gene expression in adolescents exposed to heavy metals living in the Milazzo-Valle del Mela area (Sicily, Italy).

Pizzino G, Bitto A, Interdonato M, Galfo F, Irrera N, Mecchio A, Pallio G, Ramistella V, De Luca F, Minutoli L, Squadrito F, Altavilla D.

Redox Biol. 2014 May 21;2:686-93. doi: 10.1016/j.redox.2014.05.003. eCollection 2014.

40.

Inhibitors of apoptosis proteins in experimental benign prostatic hyperplasia: effects of serenoa repens, selenium and lycopene.

Minutoli L, Altavilla D, Marini H, Rinaldi M, Irrera N, Pizzino G, Bitto A, Arena S, Cimino S, Squadrito F, Russo GI, Morgia G.

J Biomed Sci. 2014 Mar 10;21:19. doi: 10.1186/1423-0127-21-19.

41.

The effect of PDRN, an adenosine receptor A2A agonist, on the healing of chronic diabetic foot ulcers: results of a clinical trial.

Squadrito F, Bitto A, Altavilla D, Arcoraci V, De Caridi G, De Feo ME, Corrao S, Pallio G, Sterrantino C, Minutoli L, Saitta A, Vaccaro M, Cucinotta D.

J Clin Endocrinol Metab. 2014 May;99(5):E746-53. doi: 10.1210/jc.2013-3569. Epub 2014 Jan 31. Erratum in: J Clin Endocrinol Metab. 2015 Feb;100(2):763.

PMID:
24483158
42.

Effects of ischaemic post-conditioning on the early and late testicular damage after experimental testis ischaemia-reperfusion.

Minutoli L, Irrera N, Squadrito F, Marini H, Nicotina PA, Arena S, Romeo C, Antonuccio P, Altavilla D.

Andrology. 2014 Jan;2(1):76-82. doi: 10.1111/j.2047-2927.2013.00154.x. Epub 2013 Nov 26.

43.

Genistein and endothelial function in postmenopausal women with metabolic syndrome.

Irace C, Marini H, Bitto A, Altavilla D, Polito F, Adamo EB, Arcoraci V, Minutoli L, Di Benedetto A, Di Vieste G, de Gregorio C, Gnasso A, Corrao S, Licata G, Squadrito F.

Eur J Clin Invest. 2013 Oct;43(10):1025-31. doi: 10.1111/eci.12139. Epub 2013 Jul 30.

PMID:
23899172
44.

Genistein in the metabolic syndrome: results of a randomized clinical trial.

Squadrito F, Marini H, Bitto A, Altavilla D, Polito F, Adamo EB, D'Anna R, Arcoraci V, Burnett BP, Minutoli L, Di Benedetto A, Di Vieste G, Cucinotta D, de Gregorio C, Russo S, Corrado F, Saitta A, Irace C, Corrao S, Licata G.

J Clin Endocrinol Metab. 2013 Aug;98(8):3366-74. doi: 10.1210/jc.2013-1180. Epub 2013 Jul 3.

PMID:
23824420
45.

Relaxin improves multiple markers of wound healing and ameliorates the disturbed healing pattern of genetically diabetic mice.

Bitto A, Irrera N, Minutoli L, Calò M, Lo Cascio P, Caccia P, Pizzino G, Pallio G, Micali A, Vaccaro M, Saitta A, Squadrito F, Altavilla D.

Clin Sci (Lond). 2013 Dec;125(12):575-85. doi: 10.1042/CS20130105.

46.

Effects of Serenoa repens, selenium and lycopene (Profluss®) on chronic inflammation associated with benign prostatic hyperplasia: results of "FLOG" (Flogosis and Profluss in Prostatic and Genital Disease), a multicentre Italian study.

Morgia G, Cimino S, Favilla V, Russo GI, Squadrito F, Mucciardi G, Masieri L, Minutoli L, Grosso G, Castelli T.

Int Braz J Urol. 2013 Mar-Apr;39(2):214-21. doi: 10.1590/S1677-5538.IBJU.2013.02.10.

47.

Serenoa Repens, lycopene and selenium: a triple therapeutic approach to manage benign prostatic hyperplasia.

Minutoli L, Bitto A, Squadrito F, Marini H, Irrera N, Morgia G, Passantino A, Altavilla D.

Curr Med Chem. 2013;20(10):1306-12. Review.

PMID:
23432584
48.

Porcine derived relaxin stimulates new vessel formation and improves the disturbed wound healing of the genetically diabetic mice.

Squadrito F, Bitto A, Irrera N, Minutoli L, Caccia P, Altavilla D.

Ital J Anat Embryol. 2013;118(1 Suppl):66-70.

PMID:
24640576
49.

Adenosine receptor stimulation by polynucleotides (PDRN) reduces inflammation in experimental periodontitis.

Bitto A, Oteri G, Pisano M, Polito F, Irrera N, Minutoli L, Squadrito F, Altavilla D.

J Clin Periodontol. 2013 Jan;40(1):26-32. doi: 10.1111/jcpe.12010. Epub 2012 Oct 3.

PMID:
23033941
50.

Methotrexate Increases Skeletal Muscle GLUT4 Expression and Improves Metabolic Control in Experimental Diabetes.

Russo GT, Minutoli L, Bitto A, Altavilla D, Alessi E, Giandalia A, Romeo EL, Stagno MF, Squadrito F, Cucinotta D, Selhub J.

J Nutr Metab. 2012;2012:132056. doi: 10.1155/2012/132056. Epub 2012 Jun 13.

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