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Items: 29


Effects of Early Exposure of Isoflurane on Chronic Pain via the Mammalian Target of Rapamycin Signal Pathway.

Li Q, Mathena RP, Eregha ON, Mintz CD.

Int J Mol Sci. 2019 Oct 15;20(20). pii: E5102. doi: 10.3390/ijms20205102.


Current State of and Future Opportunities for Prediction in Microbiome Research: Report from the Mid-Atlantic Microbiome Meet-up in Baltimore on 9 January 2019.

Sakowski E, Uritskiy G, Cooper R, Gomes M, McLaren MR, Meisel JS, Mickol RL, Mintz CD, Mongodin EF, Pop M, Rahman MA, Sanchez A, Timp W, Vela JD, Wolz CM, Zackular JP, Chopyk J, Commichaux S, Davis M, Dluzen D, Ganesan SM, Haruna M, Nasko D, Regan MJ, Sarria S, Shah N, Stacy B, Taylor D, DiRuggiero J, Preheim SP.

mSystems. 2019 Oct 8;4(5). pii: e00392-19. doi: 10.1128/mSystems.00392-19.


Early Postnatal Exposure to Isoflurane Disrupts Oligodendrocyte Development and Myelin Formation in the Mouse Hippocampus.

Li Q, Mathena RP, Xu J, Eregha ON, Wen J, Mintz CD.

Anesthesiology. 2019 Nov;131(5):1077-1091. doi: 10.1097/ALN.0000000000002904.


Anesthetics disrupt growth cone guidance cue sensing through actions on the GABAA α2 receptor mediated by the immature chloride gradient.

Xu J, Xu M, Wang Y, Mathena RP, Wen J, Zhang P, Furmanski O, Mintz CD.

Neurotoxicol Teratol. 2019 Jul - Aug;74:106812. doi: 10.1016/ Epub 2019 Jun 26.


Early Developmental Exposure to Repetitive Long Duration of Midazolam Sedation Causes Behavioral and Synaptic Alterations in a Rodent Model of Neurodevelopment.

Xu J, Mathena RP, Singh S, Kim J, Long JJ, Li Q, Junn S, Blaize E, Mintz CD.

J Neurosurg Anesthesiol. 2019 Jan;31(1):151-162. doi: 10.1097/ANA.0000000000000541.


General Anesthesia Alters the Diversity and Composition of the Intestinal Microbiota in Mice.

Serbanescu MA, Mathena RP, Xu J, Santiago-Rodriguez T, Hartsell TL, Cano RJ, Mintz CD.

Anesth Analg. 2019 Oct;129(4):e126-e129. doi: 10.1213/ANE.0000000000003938.


Anesthetics disrupt brain development via actions on the mTOR pathway.

Xu J, Kang E, Mintz CD.

Commun Integr Biol. 2018 Apr 9;11(2):1-4. doi: 10.1080/19420889.2018.1451719. eCollection 2018.


Early Developmental Exposure to General Anesthetic Agents in Primary Neuron Culture Disrupts Synapse Formation via Actions on the mTOR Pathway.

Xu J, Mathena RP, Xu M, Wang Y, Chang C, Fang Y, Zhang P, Mintz CD.

Int J Mol Sci. 2018 Jul 26;19(8). pii: E2183. doi: 10.3390/ijms19082183.


Early postnatal exposure to isoflurane causes cognitive deficits and disrupts development of newborn hippocampal neurons via activation of the mTOR pathway.

Kang E, Jiang D, Ryu YK, Lim S, Kwak M, Gray CD, Xu M, Choi JH, Junn S, Kim J, Xu J, Schaefer M, Johns RA, Song H, Ming GL, Mintz CD.

PLoS Biol. 2017 Jul 6;15(7):e2001246. doi: 10.1371/journal.pbio.2001246. eCollection 2017 Jul. Erratum in: PLoS Biol. 2018 Mar 29;16(3):e1002625.


Sensitivity to isoflurane anesthesia increases in autism spectrum disorder Shank3+/∆c mutant mouse model.

Li C, Schaefer M, Gray C, Yang Y, Furmanski O, Liu S, Worley P, Mintz CD, Tao F, Johns RA.

Neurotoxicol Teratol. 2017 Mar - Apr;60:69-74. doi: 10.1016/ Epub 2016 Nov 14.


Sevoflurane Impairs Growth Cone Motility in Dissociated Murine Neurons.

Ryu YK, Mathena RP, Lim S, Kwak M, Xu M, Mintz CD.

J Neurosurg Anesthesiol. 2016 Oct;28(4):405-412.


Molecular Mechanisms of Anesthetic Neurotoxicity: A Review of the Current Literature.

Jackson WM, Gray CD, Jiang D, Schaefer ML, Connor C, Mintz CD.

J Neurosurg Anesthesiol. 2016 Oct;28(4):361-372. Review.


Neurogenesis and developmental anesthetic neurotoxicity.

Kang E, Berg DA, Furmanski O, Jackson WM, Ryu YK, Gray CD, Mintz CD.

Neurotoxicol Teratol. 2017 Mar - Apr;60:33-39. doi: 10.1016/ Epub 2016 Oct 14. Review.


Neurotoxic Properties of Propofol Sedation Following Traumatic Brain Injury.

Woldegerima N, Rosenblatt K, Mintz CD.

Crit Care Med. 2016 Feb;44(2):455-6. doi: 10.1097/CCM.0000000000001322. No abstract available.


Evidence of an association between brain cellular injury and cognitive decline after non-cardiac surgery.

Rappold T, Laflam A, Hori D, Brown C, Brandt J, Mintz CD, Sieber F, Gottschalk A, Yenokyan G, Everett A, Hogue CW.

Br J Anaesth. 2016 Jan;116(1):83-9. doi: 10.1093/bja/aev415.


The changes of oligodendrocytes induced by anesthesia during brain development.

Jiang D, Lim S, Kwak M, Ryu YK, Mintz CD.

Neural Regen Res. 2015 Sep;10(9):1386-7. doi: 10.4103/1673-5374.165244. No abstract available. Erratum in: Neural Regen Res. 2016 Jul;11(7):1089.


Effects of Neonatal Hypoxic-Ischemic Injury and Hypothermic Neuroprotection on Neural Progenitor Cells in the Mouse Hippocampus.

Kwak M, Lim S, Kang E, Furmanski O, Song H, Ryu YK, Mintz CD.

Dev Neurosci. 2015;37(4-5):428-39. doi: 10.1159/000430862. Epub 2015 Jun 13.


Conversion of hemiblock to complete heart block by intraoperative motor-evoked potential monitoring.

Bicket MC, Ritzl EK, Tamargo RJ, Mintz CD.

A A Case Rep. 2014 Nov 15;3(10):137-9. doi: 10.1213/XAA.0000000000000095.


Neuroprotective properties of xenon in traumatic brain injury.

Ryu YK, Mintz CD.

Crit Care Med. 2015 Jan;43(1):250-1. doi: 10.1097/CCM.0000000000000662. No abstract available.


Isoflurane impairs the capacity of astrocytes to support neuronal development in a mouse dissociated coculture model.

Ryu YK, Khan S, Smith SC, Mintz CD.

J Neurosurg Anesthesiol. 2014 Oct;26(4):363-8. doi: 10.1097/ANA.0000000000000119.


Review: effects of anesthetics on brain circuit formation.

Wagner M, Ryu YK, Smith SC, Patel P, Mintz CD.

J Neurosurg Anesthesiol. 2014 Oct;26(4):358-62. doi: 10.1097/ANA.0000000000000118. Review. Erratum in: J Neurosurg Anesthesiol. 2015 Jan;27(1):85. Patel, Piyush [added].


Anesthetics interfere with axon guidance in developing mouse neocortical neurons in vitro via a γ-aminobutyric acid type A receptor mechanism.

Mintz CD, Barrett KM, Smith SC, Benson DL, Harrison NL.

Anesthesiology. 2013 Apr;118(4):825-33. doi: 10.1097/ALN.0b013e318287b850.


Anesthetics interfere with the polarization of developing cortical neurons.

Mintz CD, Smith SC, Barrett KM, Benson DL.

J Neurosurg Anesthesiol. 2012 Oct;24(4):368-75. doi: 10.1097/ANA.0b013e31826a03a6.


Preclinical research into the effects of anesthetics on the developing brain: promises and pitfalls.

Mintz CD, Wagner M, Loepke AW.

J Neurosurg Anesthesiol. 2012 Oct;24(4):362-7. doi: 10.1097/ANA.0b013e31826a0495. Review.


Effects of ethanol on axon outgrowth and branching in developing rat cortical neurons.

Hoffman EJ, Mintz CD, Wang S, McNickle DG, Salton SR, Benson DL.

Neuroscience. 2008 Dec 2;157(3):556-65. doi: 10.1016/j.neuroscience.2008.08.071. Epub 2008 Sep 25.


ERM proteins regulate growth cone responses to Sema3A.

Mintz CD, Carcea I, McNickle DG, Dickson TC, Ge Y, Salton SR, Benson DL.

J Comp Neurol. 2008 Oct 1;510(4):351-66. doi: 10.1002/cne.21799.


A randomized blinded comparison of two methods used for venous antistasis in tetraplegia.

Nash MS, Mintz CD, Montalvo BM, Jacobs PL.

J Spinal Cord Med. 2000 Winter;23(4):221-7.


ERMs colocalize transiently with L1 during neocortical axon outgrowth.

Mintz CD, Dickson TC, Gripp ML, Salton SR, Benson DL.

J Comp Neurol. 2003 Sep 29;464(4):438-48.


Functional binding interaction identified between the axonal CAM L1 and members of the ERM family.

Dickson TC, Mintz CD, Benson DL, Salton SR.

J Cell Biol. 2002 Jun 24;157(7):1105-12. Epub 2002 Jun 17. Erratum in: J Cell Biol 2002 Aug 19;158(4):817.

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