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Items: 1 to 50 of 73

1.

Corrigendum: Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.

Iizuka T, Kamiya K, Gotoh S, Sugitani Y, Suzuki M, Noda T, Minowa O, Ikeda K.

Hum Mol Genet. 2019 Jul 15;28(14):2458. doi: 10.1093/hmg/ddz041. No abstract available.

PMID:
30816417
2.

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

Bowl MR, Simon MM, Ingham NJ, Greenaway S, Santos L, Cater H, Taylor S, Mason J, Kurbatova N, Pearson S, Bower LR, Clary DA, Meziane H, Reilly P, Minowa O, Kelsey L; International Mouse Phenotyping Consortium, Tocchini-Valentini GP, Gao X, Bradley A, Skarnes WC, Moore M, Beaudet AL, Justice MJ, Seavitt J, Dickinson ME, Wurst W, de Angelis MH, Herault Y, Wakana S, Nutter LMJ, Flenniken AM, McKerlie C, Murray SA, Svenson KL, Braun RE, West DB, Lloyd KCK, Adams DJ, White J, Karp N, Flicek P, Smedley D, Meehan TF, Parkinson HE, Teboul LM, Wells S, Steel KP, Mallon AM, Brown SDM.

Nat Commun. 2017 Oct 12;8(1):886. doi: 10.1038/s41467-017-00595-4.

3.

In Vitro Models of GJB2-Related Hearing Loss Recapitulate Ca2+ Transients via a Gap Junction Characteristic of Developing Cochlea.

Fukunaga I, Fujimoto A, Hatakeyama K, Aoki T, Nishikawa A, Noda T, Minowa O, Kurebayashi N, Ikeda K, Kamiya K.

Stem Cell Reports. 2016 Dec 13;7(6):1023-1036. doi: 10.1016/j.stemcr.2016.10.005. Epub 2016 Nov 10.

4.

Novel allelic mutations in murine Serca2 induce differential development of squamous cell tumors.

Toki H, Minowa O, Inoue M, Motegi H, Karashima Y, Ikeda A, Kaneda H, Sakuraba Y, Saiki Y, Wakana S, Suzuki H, Gondo Y, Shiroishi T, Noda T.

Biochem Biophys Res Commun. 2016 Aug 5;476(4):175-182. doi: 10.1016/j.bbrc.2016.04.136. Epub 2016 Apr 27.

PMID:
27131742
5.

Mouse models for ROS1-fusion-positive lung cancers and their application to the analysis of multikinase inhibitor efficiency.

Inoue M, Toki H, Matsui J, Togashi Y, Dobashi A, Fukumura R, Gondo Y, Minowa O, Tanaka N, Mori S, Takeuchi K, Noda T.

Carcinogenesis. 2016 May;37(5):452-60. doi: 10.1093/carcin/bgw028. Epub 2016 Mar 10.

PMID:
26964870
6.

Identification of Reliable Components in Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS): a Data-Driven Approach across Metabolic Processes.

Motegi H, Tsuboi Y, Saga A, Kagami T, Inoue M, Toki H, Minowa O, Noda T, Kikuchi J.

Sci Rep. 2015 Nov 4;5:15710. doi: 10.1038/srep15710.

7.

Deformation of the Outer Hair Cells and the Accumulation of Caveolin-2 in Connexin 26 Deficient Mice.

Anzai T, Fukunaga I, Hatakeyama K, Fujimoto A, Kobayashi K, Nishikawa A, Aoki T, Noda T, Minowa O, Ikeda K, Kamiya K.

PLoS One. 2015 Oct 22;10(10):e0141258. doi: 10.1371/journal.pone.0141258. eCollection 2015.

8.

Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.

Iizuka T, Kamiya K, Gotoh S, Sugitani Y, Suzuki M, Noda T, Minowa O, Ikeda K.

Hum Mol Genet. 2015 Jul 1;24(13):3651-61. doi: 10.1093/hmg/ddv109. Epub 2015 Mar 23.

PMID:
25801282
9.

Deficiency of transcription factor Brn4 disrupts cochlear gap junction plaques in a model of DFN3 non-syndromic deafness.

Kidokoro Y, Karasawa K, Minowa O, Sugitani Y, Noda T, Ikeda K, Kamiya K.

PLoS One. 2014 Sep 26;9(9):e108216. doi: 10.1371/journal.pone.0108216. eCollection 2014.

10.

Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors.

Toki H, Inoue M, Minowa O, Motegi H, Saiki Y, Wakana S, Masuya H, Gondo Y, Shiroishi T, Yao R, Noda T.

Cancer Sci. 2014 Oct;105(10):1360-8. doi: 10.1111/cas.12495. Epub 2014 Sep 29.

11.

Assembly of the cochlear gap junction macromolecular complex requires connexin 26.

Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y, Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K.

J Clin Invest. 2014 Apr;124(4):1598-607. doi: 10.1172/JCI67621. Epub 2014 Mar 3.

12.

Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.

Funabiki M, Kato H, Miyachi Y, Toki H, Motegi H, Inoue M, Minowa O, Yoshida A, Deguchi K, Sato H, Ito S, Shiroishi T, Takeyasu K, Noda T, Fujita T.

Immunity. 2014 Feb 20;40(2):199-212. doi: 10.1016/j.immuni.2013.12.014. Epub 2014 Feb 13.

13.

Novel mouse model for Gardner syndrome generated by a large-scale N-ethyl-N-nitrosourea mutagenesis program.

Toki H, Inoue M, Motegi H, Minowa O, Kanda H, Yamamoto N, Ikeda A, Karashima Y, Matsui J, Kaneda H, Miura I, Suzuki T, Wakana S, Masuya H, Gondo Y, Shiroishi T, Akiyama T, Yao R, Noda T.

Cancer Sci. 2013 Jul;104(7):937-44. doi: 10.1111/cas.12161. Epub 2013 May 18.

14.

SDOP-DB: a comparative standardized-protocol database for mouse phenotypic analyses.

Tanaka N, Waki K, Kaneda H, Suzuki T, Yamada I, Furuse T, Kobayashi K, Motegi H, Toki H, Inoue M, Minowa O, Noda T, Takao K, Miyakawa T, Takahashi A, Koide T, Wakana S, Masuya H.

Bioinformatics. 2010 Apr 15;26(8):1133-4. doi: 10.1093/bioinformatics/btq095. Epub 2010 Mar 1.

15.

Introduction to the Japan Mouse Clinic at the RIKEN BioResource Center.

Wakana S, Suzuki T, Furuse T, Kobayashi K, Miura I, Kaneda H, Yamada I, Motegi H, Toki H, Inoue M, Minowa O, Noda T, Waki K, Tanaka N, Masuya H, Obata Y.

Exp Anim. 2009 Oct;58(5):443-50. Review.

16.

Osteoporotic bone formation in mice lacking tob2; involvement of Tob2 in RANK ligand expression and osteoclasts differentiation.

Ajima R, Akiyama T, Usui M, Yoneda M, Yoshida Y, Nakamura T, Minowa O, Noda M, Tanaka S, Noda T, Yamamoto T.

FEBS Lett. 2008 Apr 16;582(9):1313-8. doi: 10.1016/j.febslet.2008.03.012. Epub 2008 Mar 20.

17.

Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice.

Kinoshita A, Wanibuchi H, Morimura K, Wei M, Nakae D, Arai T, Minowa O, Noda T, Nishimura S, Fukushima S.

Cancer Sci. 2007 Jun;98(6):803-14. Epub 2007 Apr 18.

18.
19.

Implementation of the modified-SHIRPA protocol for screening of dominant phenotypes in a large-scale ENU mutagenesis program.

Masuya H, Inoue M, Wada Y, Shimizu A, Nagano J, Kawai A, Inoue A, Kagami T, Hirayama T, Yamaga A, Kaneda H, Kobayashi K, Minowa O, Miura I, Gondo Y, Noda T, Wakana S, Shiroishi T.

Mamm Genome. 2005 Nov;16(11):829-37. Epub 2005 Nov 11.

PMID:
16284798
20.

Molecular characterization of ENU mouse mutagenesis and archives.

Sakuraba Y, Sezutsu H, Takahasi KR, Tsuchihashi K, Ichikawa R, Fujimoto N, Kaneko S, Nakai Y, Uchiyama M, Goda N, Motoi R, Ikeda A, Karashima Y, Inoue M, Kaneda H, Masuya H, Minowa O, Noguchi H, Toyoda A, Sakaki Y, Wakana S, Noda T, Shiroishi T, Gondo Y.

Biochem Biophys Res Commun. 2005 Oct 21;336(2):609-16.

PMID:
16139793
21.

Development and implementation of a database system to manage a large-scale mouse ENU-mutagenesis program.

Masuya H, Nakai Y, Motegi H, Niinaya N, Kida Y, Kaneko Y, Aritake H, Suzuki N, Ishii J, Koorikawa K, Suzuki T, Inoue M, Kobayashi K, Toki H, Wada Y, Kaneda H, Ishijima J, Takahashi KR, Minowa O, Noda T, Wakana S, Gondo Y, Shiroishi T.

Mamm Genome. 2004 May;15(5):404-11.

PMID:
15170230
22.

A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program.

Inoue M, Sakuraba Y, Motegi H, Kubota N, Toki H, Matsui J, Toyoda Y, Miwa I, Terauchi Y, Kadowaki T, Shigeyama Y, Kasuga M, Adachi T, Fujimoto N, Matsumoto R, Tsuchihashi K, Kagami T, Inoue A, Kaneda H, Ishijima J, Masuya H, Suzuki T, Wakana S, Gondo Y, Minowa O, Shiroishi T, Noda T.

Hum Mol Genet. 2004 Jun 1;13(11):1147-57. Epub 2004 Apr 21.

PMID:
15102714
23.

Crucial roles of Brn1 in distal tubule formation and function in mouse kidney.

Nakai S, Sugitani Y, Sato H, Ito S, Miura Y, Ogawa M, Nishi M, Jishage K, Minowa O, Noda T.

Development. 2003 Oct;130(19):4751-9.

24.

Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA.

Arai T, Kelly VP, Komoro K, Minowa O, Noda T, Nishimura S.

Cancer Res. 2003 Jul 15;63(14):4287-92.

25.

High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress.

Arai T, Kelly VP, Minowa O, Noda T, Nishimura S.

Carcinogenesis. 2002 Dec;23(12):2005-10.

PMID:
12507922
26.

Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons.

Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T.

Genes Dev. 2002 Jul 15;16(14):1760-5.

27.

Late-onset hearing loss in a mouse model of DFN3 non-syndromic deafness: morphologic and immunohistochemical analyses.

Xia AP, Kikuchi T, Minowa O, Katori Y, Oshima T, Noda T, Ikeda K.

Hear Res. 2002 Apr;166(1-2):150-8.

PMID:
12062767
28.

[MR imaging of small bowel with water administration].

Minowa O, Ozaki Y, Sumi Y.

Nihon Igaku Hoshasen Gakkai Zasshi. 2002 Feb;62(2):73-8. Japanese.

PMID:
11905035
29.

Role of CCK-A receptor for pancreatic function in mice: a study in CCK-A receptor knockout mice.

Takiguchi S, Suzuki S, Sato Y, Kanai S, Miyasaka K, Jimi A, Shinozaki H, Takata Y, Funakoshi A, Kono A, Minowa O, Kobayashi T, Noda T.

Pancreas. 2002 Apr;24(3):276-83.

PMID:
11893936
30.

Small bowel intussusception caused by intestinal angiosarcomatosis: usefulness of MR enteroclysis with infusion of water through a nasojejunal catheter.

Ogawa S, Minowa O, Ozaki Y, Kuwatsuru R, Sumi Y, Maehara T.

Eur Radiol. 2002 Mar;12(3):534-6. Epub 2001 Sep 14.

PMID:
11870466
31.

A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice.

Kobayashi T, Minowa O, Sugitani Y, Takai S, Mitani H, Kobayashi E, Noda T, Hino O.

Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8762-7. Epub 2001 Jul 3.

32.

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis.

Tobiume K, Matsuzawa A, Takahashi T, Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T, Ichijo H.

EMBO Rep. 2001 Mar;2(3):222-8.

33.

Negative regulation of BMP/Smad signaling by Tob in osteoblasts.

Yoshida Y, Tanaka S, Umemori H, Minowa O, Usui M, Ikematsu N, Hosoda E, Imamura T, Kuno J, Yamashita T, Miyazono K, Noda M, Noda T, Yamamoto T.

Cell. 2000 Dec 22;103(7):1085-97.

34.

Emphysematous pyelonephritis- conversion of type i to type II appearance on serial CT studies.

Komura S, Shindoh N, Minowa O, Ozaki Y, Kyogoku S, Sumi Y.

Clin Imaging. 1999 Nov-Dec;23(6):386-8.

PMID:
10899423
35.

Altered pain responses in mice lacking alpha 1E subunit of the voltage-dependent Ca2+ channel.

Saegusa H, Kurihara T, Zong S, Minowa O, Kazuno A, Han W, Matsuda Y, Yamanaka H, Osanai M, Noda T, Tanabe T.

Proc Natl Acad Sci U S A. 2000 May 23;97(11):6132-7.

36.

BMP type II receptor is required for gastrulation and early development of mouse embryos.

Beppu H, Kawabata M, Hamamoto T, Chytil A, Minowa O, Noda T, Miyazono K.

Dev Biol. 2000 May 1;221(1):249-58.

37.

Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice.

Minowa O, Arai T, Hirano M, Monden Y, Nakai S, Fukuda M, Itoh M, Takano H, Hippou Y, Aburatani H, Masumura K, Nohmi T, Nishimura S, Noda T.

Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4156-61.

38.

Zic2 regulates the kinetics of neurulation.

Nagai T, Aruga J, Minowa O, Sugimoto T, Ohno Y, Noda T, Mikoshiba K.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1618-23.

39.

Paratesticular aggressive fibromatosis: CT findings.

Sumi Y, Shindoh N, Komura S, Minowa O, Ozaki Y, Kyogoku S, Katayama H.

Abdom Imaging. 2000 Mar-Apr;25(2):210-2.

PMID:
10675470
40.

Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha.

Orimo A, Inoue S, Minowa O, Tominaga N, Tomioka Y, Sato M, Kuno J, Hiroi H, Shimizu Y, Suzuki M, Noda T, Muramatsu M.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12027-32.

41.

MR imaging of the small bowel using water as a contrast agent in a preliminary study with healthy volunteers.

Minowa O, Ozaki Y, Kyogoku S, Shindoh N, Sumi Y, Katayama H.

AJR Am J Roentgenol. 1999 Sep;173(3):581-2. No abstract available.

PMID:
10470883
42.

Altered cochlear fibrocytes in a mouse model of DFN3 nonsyndromic deafness.

Minowa O, Ikeda K, Sugitani Y, Oshima T, Nakai S, Katori Y, Suzuki M, Furukawa M, Kawase T, Zheng Y, Ogura M, Asada Y, Watanabe K, Yamanaka H, Gotoh S, Nishi-Takeshima M, Sugimoto T, Kikuchi T, Takasaka T, Noda T.

Science. 1999 Aug 27;285(5432):1408-11.

43.

Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice.

Kobayashi T, Minowa O, Kuno J, Mitani H, Hino O, Noda T.

Cancer Res. 1999 Mar 15;59(6):1206-11.

44.

Successful germ-line transmission of chimeras generated by coculture aggregation with J1 ES cells and eight-cell embryos.

Orimo A, Tominaga N, Suzuki M, Kawakami T, Kuno J, Sato M, Minowa O, Inoue S, Kato S, Noda T, Muramatsu M.

Anal Biochem. 1999 Apr 10;269(1):204-7. No abstract available.

PMID:
10094797
45.

[2D-FASE MRCP for pediatrics with congenital biliary dilatation: usefulness of non-breath-hold one-shot MRCP].

Kuwatsuru R, Yamataka A, Irimoto M, Minowa O, Makita J, Kassai Y, Miyano T, Katayama H.

Nihon Igaku Hoshasen Gakkai Zasshi. 1998 Dec;58(14):807-10. Japanese.

PMID:
10028832
46.

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice.

Hiratsuka S, Minowa O, Kuno J, Noda T, Shibuya M.

Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9349-54.

47.

[New medicinal action of native hormone].

Orimo A, Inoue S, Minowa O, Ikeda K, Hiroi H, Ogawa S, Watanabe T, Kuno J, Noda T, Muramatsu M.

Nihon Yakurigaku Zasshi. 1997 Oct;110 Suppl 1:44P-49P. Review. Japanese.

PMID:
9503404
48.

Mouse Zic1 is involved in cerebellar development.

Aruga J, Minowa O, Yaginuma H, Kuno J, Nagai T, Noda T, Mikoshiba K.

J Neurosci. 1998 Jan 1;18(1):284-93.

49.

cDNA cloning and genomic organization of the mouse BMP type II receptor.

Beppu H, Minowa O, Miyazono K, Kawabata M.

Biochem Biophys Res Commun. 1997 Jun 27;235(3):499-504.

PMID:
9207184
50.

G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivo.

Nagata A, Ito M, Iwata N, Kuno J, Takano H, Minowa O, Chihara K, Matsui T, Noda T.

Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11825-30.

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