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Items: 1 to 50 of 151

1.

Survival and clinical outcomes of patients with melanoma brain metastasis in the era of checkpoint inhibitors and targeted therapies.

Vosoughi E, Lee JM, Miller JR, Nosrati M, Minor DR, Abendroth R, Lee JW, Andrews BT, Leng LZ, Wu M, Leong SP, Kashani-Sabet M, Kim KB.

BMC Cancer. 2018 Apr 27;18(1):490. doi: 10.1186/s12885-018-4374-x.

2.

Hypervirulent Group A Streptococcus of Genotype emm3 Invades the Vascular System in Pulmonary Infection of Mice.

Lei B, Minor D, Feng W, Liu M.

Infect Immun. 2018 May 22;86(6). pii: e00080-18. doi: 10.1128/IAI.00080-18. Print 2018 Jun.

PMID:
29610254
3.

A Calmodulin C-Lobe Ca2+-Dependent Switch Governs Kv7 Channel Function.

Chang A, Abderemane-Ali F, Hura GL, Rossen ND, Gate RE, Minor DL Jr.

Neuron. 2018 Feb 21;97(4):836-852.e6. doi: 10.1016/j.neuron.2018.01.035. Epub 2018 Feb 8.

PMID:
29429937
4.

Global versus local mechanisms of temperature sensing in ion channels.

Arrigoni C, Minor DL Jr.

Pflugers Arch. 2018 May;470(5):733-744. doi: 10.1007/s00424-017-2102-z. Epub 2018 Jan 17. Review.

PMID:
29340775
5.

Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent.

Ely LK, Lolicato M, David T, Lowe K, Kim YC, Samuel D, Bessette P, Garcia JL, Mikita T, Minor DL Jr, Coughlin SR.

Structure. 2018 Feb 6;26(2):187-198.e4. doi: 10.1016/j.str.2017.12.010. Epub 2018 Jan 11.

PMID:
29336885
6.

Cryo-EM structures of the TMEM16A calcium-activated chloride channel.

Dang S, Feng S, Tien J, Peters CJ, Bulkley D, Lolicato M, Zhao J, Zuberbühler K, Ye W, Qi L, Chen T, Craik CS, Jan YN, Minor DL Jr, Cheng Y, Jan LY.

Nature. 2017 Dec 21;552(7685):426-429. doi: 10.1038/nature25024. Epub 2017 Dec 13.

7.

Channel surfing uncovers a dual-use transporter.

Minor DL Jr.

EMBO J. 2017 Nov 15;36(22):3272-3273. doi: 10.15252/embj.201798304. Epub 2017 Oct 19. No abstract available.

PMID:
29051229
8.

Prolonged survival after intraperitoneal interleukin-2 immunotherapy for recurrent ovarian cancer.

Minor DR, Moores SP, Chan JK.

Gynecol Oncol Rep. 2017 Sep 25;22:43-44. doi: 10.1016/j.gore.2017.09.009. eCollection 2017 Nov.

9.

Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens.

DeFalco J, Harbell M, Manning-Bog A, Baia G, Scholz A, Millare B, Sumi M, Zhang D, Chu F, Dowd C, Zuno-Mitchell P, Kim D, Leung Y, Jiang S, Tang X, Williamson KS, Chen X, Carroll SM, Espiritu Santo G, Haaser N, Nguyen N, Giladi E, Minor D, Tan YC, Sokolove JB, Steinman L, Serafini TA, Cavet G, Greenberg NM, Glanville J, Volkmuth W, Emerling DE, Robinson WH.

Clin Immunol. 2018 Feb;187:37-45. doi: 10.1016/j.clim.2017.10.002. Epub 2017 Oct 12.

11.

K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.

Lolicato M, Arrigoni C, Mori T, Sekioka Y, Bryant C, Clark KA, Minor DL Jr.

Nature. 2017 Jul 20;547(7663):364-368. doi: 10.1038/nature22988. Epub 2017 Jul 10.

12.

Overall Survival in Patients With Advanced Melanoma Who Received Nivolumab Versus Investigator's Choice Chemotherapy in CheckMate 037: A Randomized, Controlled, Open-Label Phase III Trial.

Larkin J, Minor D, D'Angelo S, Neyns B, Smylie M, Miller WH Jr, Gutzmer R, Linette G, Chmielowski B, Lao CD, Lorigan P, Grossmann K, Hassel JC, Sznol M, Daud A, Sosman J, Khushalani N, Schadendorf D, Hoeller C, Walker D, Kong G, Horak C, Weber J.

J Clin Oncol. 2018 Feb 1;36(4):383-390. doi: 10.1200/JCO.2016.71.8023. Epub 2017 Jul 3.

PMID:
28671856
13.

Role of human rhinovirus in triggering human airway epithelial-mesenchymal transition.

Minor DM, Proud D.

Respir Res. 2017 May 30;18(1):110. doi: 10.1186/s12931-017-0595-9.

14.

Stapled Voltage-Gated Calcium Channel (CaV) α-Interaction Domain (AID) Peptides Act As Selective Protein-Protein Interaction Inhibitors of CaV Function.

Findeisen F, Campiglio M, Jo H, Abderemane-Ali F, Rumpf CH, Pope L, Rossen ND, Flucher BE, DeGrado WF, Minor DL Jr.

ACS Chem Neurosci. 2017 Jun 21;8(6):1313-1326. doi: 10.1021/acschemneuro.6b00454. Epub 2017 Mar 17.

15.

Null Mutations of Group A Streptococcus Orphan Kinase RocA: Selection in Mouse Infection and Comparison with CovS Mutations in Alteration of In Vitro and In Vivo Protease SpeB Expression and Virulence.

Feng W, Minor D, Liu M, Li J, Ishaq SL, Yeoman C, Lei B.

Infect Immun. 2016 Dec 29;85(1). pii: e00790-16. doi: 10.1128/IAI.00790-16. Print 2017 Jan.

16.

Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial.

Hodi FS, Chesney J, Pavlick AC, Robert C, Grossmann KF, McDermott DF, Linette GP, Meyer N, Giguere JK, Agarwala SS, Shaheen M, Ernstoff MS, Minor DR, Salama AK, Taylor MH, Ott PA, Horak C, Gagnier P, Jiang J, Wolchok JD, Postow MA.

Lancet Oncol. 2016 Nov;17(11):1558-1568. doi: 10.1016/S1470-2045(16)30366-7. Epub 2016 Sep 9.

17.

Talimogene Laherparepvec in Combination With Ipilimumab in Previously Untreated, Unresectable Stage IIIB-IV Melanoma.

Puzanov I, Milhem MM, Minor D, Hamid O, Li A, Chen L, Chastain M, Gorski KS, Anderson A, Chou J, Kaufman HL, Andtbacka RH.

J Clin Oncol. 2016 Aug 1;34(22):2619-26. doi: 10.1200/JCO.2016.67.1529. Epub 2016 Jun 13.

PMID:
27298410
18.

Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.

Arrigoni C, Rohaim A, Shaya D, Findeisen F, Stein RA, Nurva SR, Mishra S, Mchaourab HS, Minor DL Jr.

Cell. 2016 Feb 25;164(5):922-36. doi: 10.1016/j.cell.2016.02.001.

19.

Let It Go and Open Up, an Ensemble of Ion Channel Active States.

Minor DL Jr.

Cell. 2016 Feb 11;164(4):597-8. doi: 10.1016/j.cell.2016.01.037.

20.

Determinants of pulse pressure and annual rates of change in the Atherosclerosis Risk in Communities study.

Butler KR Jr, Penman AD, Minor DS, Mosley TH Jr.

J Hypertens. 2015 Dec;33(12):2463-70. doi: 10.1097/HJH.0000000000000731.

PMID:
26378679
21.

Decisional Capacity in Amyotrophic Lateral Sclerosis.

Khin Khin E, Minor D, Holloway A, Pelleg A.

J Am Acad Psychiatry Law. 2015 Jun;43(2):210-7. Review.

PMID:
26071511
22.

Severe gastrointestinal toxicity with administration of trametinib in combination with dabrafenib and ipilimumab.

Minor DR, Puzanov I, Callahan MK, Hug BA, Hoos A.

Pigment Cell Melanoma Res. 2015 Sep;28(5):611-2. doi: 10.1111/pcmr.12383. Epub 2015 Jun 23. No abstract available.

23.

Nivolumab and ipilimumab versus ipilimumab in untreated melanoma.

Postow MA, Chesney J, Pavlick AC, Robert C, Grossmann K, McDermott D, Linette GP, Meyer N, Giguere JK, Agarwala SS, Shaheen M, Ernstoff MS, Minor D, Salama AK, Taylor M, Ott PA, Rollin LM, Horak C, Gagnier P, Wolchok JD, Hodi FS.

N Engl J Med. 2015 May 21;372(21):2006-17. doi: 10.1056/NEJMoa1414428. Epub 2015 Apr 20.

24.

Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial.

Weber JS, D'Angelo SP, Minor D, Hodi FS, Gutzmer R, Neyns B, Hoeller C, Khushalani NI, Miller WH Jr, Lao CD, Linette GP, Thomas L, Lorigan P, Grossmann KF, Hassel JC, Maio M, Sznol M, Ascierto PA, Mohr P, Chmielowski B, Bryce A, Svane IM, Grob JJ, Krackhardt AM, Horak C, Lambert A, Yang AS, Larkin J.

Lancet Oncol. 2015 Apr;16(4):375-84. doi: 10.1016/S1470-2045(15)70076-8. Epub 2015 Mar 18.

PMID:
25795410
25.

The role of BPTF in melanoma progression and in response to BRAF-targeted therapy.

Dar AA, Nosrati M, Bezrookove V, de Semir D, Majid S, Thummala S, Sun V, Tong S, Leong SP, Minor D, Billings PR, Soroceanu L, Debs R, Miller JR 3rd, Sagebiel RW, Kashani-Sabet M.

J Natl Cancer Inst. 2015 Feb 23;107(5). pii: djv034. doi: 10.1093/jnci/djv034.

26.

Insights into the molecular foundations of electrical excitation.

Gaudet R, Roux B, Minor DL Jr.

J Mol Biol. 2015 Jan 16;427(1):1-2. doi: 10.1016/j.jmb.2014.12.006. No abstract available.

27.

Transmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.

Lolicato M, Riegelhaupt PM, Arrigoni C, Clark KA, Minor DL Jr.

Neuron. 2014 Dec 17;84(6):1198-212. doi: 10.1016/j.neuron.2014.11.017. Epub 2014 Dec 11.

28.

Phase 2 Study of Intralesional PV-10 in Refractory Metastatic Melanoma.

Thompson JF, Agarwala SS, Smithers BM, Ross MI, Scoggins CR, Coventry BJ, Neuhaus SJ, Minor DR, Singer JM, Wachter EA.

Ann Surg Oncol. 2015 Jul;22(7):2135-42. doi: 10.1245/s10434-014-4169-5. Epub 2014 Oct 28.

29.
30.

TERN Residency Program: transitioning the experienced registered nurse.

Longo MA, Young D, Jones C, Shaw CA, Werner R, Minor D, Hoying C.

J Nurses Prof Dev. 2014 Jul-Aug;30(4):181-4. doi: 10.1097/NND.0000000000000063.

PMID:
25036081
31.

Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries.

Bagriantsev SN, Chatelain FC, Clark KA, Alagem N, Reuveny E, Minor DL Jr.

ACS Chem Neurosci. 2014 Sep 17;5(9):812-22. doi: 10.1021/cn5000698. Epub 2014 Jul 16.

32.

Chocolate--guilty pleasure or healthy supplement?

Latham LS, Hensen ZK, Minor DS.

J Clin Hypertens (Greenwich). 2014 Feb;16(2):101-6. Review.

PMID:
24734311
33.

Conduits of life's spark: a perspective on ion channel research since the birth of neuron.

Isacoff EY, Jan LY, Minor DL Jr.

Neuron. 2013 Oct 30;80(3):658-74. doi: 10.1016/j.neuron.2013.10.040. Review.

34.

Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels.

Shaya D, Findeisen F, Abderemane-Ali F, Arrigoni C, Wong S, Nurva SR, Loussouarn G, Minor DL Jr.

J Mol Biol. 2014 Jan 23;426(2):467-83. doi: 10.1016/j.jmb.2013.10.010. Epub 2013 Oct 10.

35.

β-Blockers and chronic obstructive pulmonary disease: inappropriate avoidance?

Minor DS, Meyer AM, Long RC, Butler KR Jr.

J Clin Hypertens (Greenwich). 2013 Dec;15(12):925-30. doi: 10.1111/jch.12204. Epub 2013 Sep 16. Review.

36.

Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma.

Ascierto PA, Minor D, Ribas A, Lebbe C, O'Hagan A, Arya N, Guckert M, Schadendorf D, Kefford RF, Grob JJ, Hamid O, Amaravadi R, Simeone E, Wilhelm T, Kim KB, Long GV, Martin AM, Mazumdar J, Goodman VL, Trefzer U.

J Clin Oncol. 2013 Sep 10;31(26):3205-11. doi: 10.1200/JCO.2013.49.8691. Epub 2013 Aug 5.

PMID:
23918947
37.

Anesthesia management of patients undergoing hyperthermic isolated limb perfusion with melphalan for melanoma treatment: an analysis of 17 cases.

Ruschulte H, Shi S, Tseng WW, Kolodzie K, Crawford PC, Schneider DB, Kashani-Sabet M, Minor D, Apfel C, Leong SP.

BMC Anesthesiol. 2013 Jul 17;13(1):15. doi: 10.1186/1471-2253-13-15.

38.

Apo states of calmodulin and CaBP1 control CaV1 voltage-gated calcium channel function through direct competition for the IQ domain.

Findeisen F, Rumpf CH, Minor DL Jr.

J Mol Biol. 2013 Sep 9;425(17):3217-34. doi: 10.1016/j.jmb.2013.06.024. Epub 2013 Jun 25.

39.

A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels.

Bagriantsev SN, Ang KH, Gallardo-Godoy A, Clark KA, Arkin MR, Renslo AR, Minor DL Jr.

ACS Chem Biol. 2013 Aug 16;8(8):1841-51. doi: 10.1021/cb400289x. Epub 2013 Jun 17.

40.

Lymphocytic vasculitis of the uterus in a patient with melanoma receiving ipilimumab.

Minor DR, Bunker SR, Doyle J.

J Clin Oncol. 2013 Jul 10;31(20):e356. doi: 10.1200/JCO.2012.47.5095. Epub 2013 Jun 3. No abstract available.

PMID:
23733772
41.

Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC).

Tien J, Lee HY, Minor DL Jr, Jan YN, Jan LY.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6352-7. doi: 10.1073/pnas.1303672110. Epub 2013 Apr 1. Erratum in: Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):E5775.

42.

Patch-clamp characterization of the MscS-like mechanosensitive channel from Silicibacter pomeroyi.

Petrov E, Palanivelu D, Constantine M, Rohde PR, Cox CD, Nomura T, Minor DL Jr, Martinac B.

Biophys J. 2013 Apr 2;104(7):1426-34. doi: 10.1016/j.bpj.2013.01.055.

43.

Using yeast to study potassium channel function and interactions with small molecules.

Bagriantsev SN, Minor DL Jr.

Methods Mol Biol. 2013;995:31-42. doi: 10.1007/978-1-62703-345-9_3.

44.

Dietary recommendations in ambulatory care: evaluation of the Southern Remedy Healthy Eating Plate.

Smith AK, Minor DS, Tillman LE, DeShazo RD, Replogle WH.

J Miss State Med Assoc. 2012 Oct;53(10):330-3.

PMID:
23210229
45.

Structure of a Ca(2+)/CaM:Kv7.4 (KCNQ4) B-helix complex provides insight into M current modulation.

Xu Q, Chang A, Tolia A, Minor DL Jr.

J Mol Biol. 2013 Jan 23;425(2):378-94. doi: 10.1016/j.jmb.2012.11.023. Epub 2012 Nov 23.

46.

Inoperable bulky melanoma responds to neoadjuvant therapy with vemurafenib.

Fadaki N, Cardona-Huerta S, Martineau L, Thummala S, Cheng ST, Bunker SR, Garcia-Kennedy R, Wang W, Minor D, Kashani-Sabet M, Leong SP.

BMJ Case Rep. 2012 Oct 22;2012. pii: bcr2012007034. doi: 10.1136/bcr-2012-007034.

47.

Successful desensitization in a case of Stevens-Johnson syndrome due to vemurafenib.

Minor DR, Rodvien R, Kashani-Sabet M.

Melanoma Res. 2012 Oct;22(5):410-1. doi: 10.1097/CMR.0b013e3283573437.

PMID:
22828249
48.

Dietary supplements and hypertension: potential benefits and precautions.

Rasmussen CB, Glisson JK, Minor DS.

J Clin Hypertens (Greenwich). 2012 Jul;14(7):467-71. doi: 10.1111/j.1751-7176.2012.00642.x. Epub 2012 May 14. Review.

49.

Metabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains.

Bagriantsev SN, Clark KA, Minor DL Jr.

EMBO J. 2012 Aug 1;31(15):3297-308. doi: 10.1038/emboj.2012.171. Epub 2012 Jun 22.

50.

A glutamate switch controls voltage-sensitive phosphatase function.

Liu L, Kohout SC, Xu Q, Müller S, Kimberlin CR, Isacoff EY, Minor DL Jr.

Nat Struct Mol Biol. 2012 May 6;19(6):633-41. doi: 10.1038/nsmb.2289.

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