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Items: 5

1.

Spatially clustered loci with multiple enhancers are frequent targets of HIV-1 integration.

Lucic B, Chen HC, Kuzman M, Zorita E, Wegner J, Minneker V, Wang W, Fronza R, Laufs S, Schmidt M, Stadhouders R, Roukos V, Vlahovicek K, Filion GJ, Lusic M.

Nat Commun. 2019 Sep 6;10(1):4059. doi: 10.1038/s41467-019-12046-3.

2.

53BP1-DNA repair enters a new liquid phase.

Piccinno R, Minneker V, Roukos V.

EMBO J. 2019 Aug 15;38(16):e102871. doi: 10.15252/embj.2019102871. Epub 2019 Jul 29.

PMID:
31355472
3.

Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.

Gothe HJ, Bouwman BAM, Gusmao EG, Piccinno R, Petrosino G, Sayols S, Drechsel O, Minneker V, Josipovic N, Mizi A, Nielsen CF, Wagner EM, Takeda S, Sasanuma H, Hudson DF, Kindler T, Baranello L, Papantonis A, Crosetto N, Roukos V.

Mol Cell. 2019 Jul 25;75(2):267-283.e12. doi: 10.1016/j.molcel.2019.05.015. Epub 2019 Jun 12.

PMID:
31202576
4.

Dynamics of Double-Strand Breaks: Implications for the Formation of Chromosome Translocations.

Gothe HJ, Minneker V, Roukos V.

Adv Exp Med Biol. 2018;1044:27-38. doi: 10.1007/978-981-13-0593-1_3. Review.

PMID:
29956289
5.

PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression.

Dörsam B, Seiwert N, Foersch S, Stroh S, Nagel G, Begaliew D, Diehl E, Kraus A, McKeague M, Minneker V, Roukos V, Reißig S, Waisman A, Moehler M, Stier A, Mangerich A, Dantzer F, Kaina B, Fahrer J.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4061-E4070. doi: 10.1073/pnas.1712345115. Epub 2018 Apr 9.

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