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Items: 1 to 50 of 156

1.

From d- to l-Monosaccharide Derivatives via Photodecarboxylation-Alkylation.

Wan ICS, Witte MD, Minnaard AJ.

Org Lett. 2019 Sep 20;21(18):7669-7673. doi: 10.1021/acs.orglett.9b03016. Epub 2019 Sep 12.

2.

Mycobacterium tuberculosis releases an antacid that remodels phagosomes.

Buter J, Cheng TY, Ghanem M, Grootemaat AE, Raman S, Feng X, Plantijn AR, Ennis T, Wang J, Cotton RN, Layre E, Ramnarine AK, Mayfield JA, Young DC, Jezek Martinot A, Siddiqi N, Wakabayashi S, Botella H, Calderon R, Murray M, Ehrt S, Snider BB, Reed MB, Oldfield E, Tan S, Rubin EJ, Behr MA, van der Wel NN, Minnaard AJ, Moody DB.

Nat Chem Biol. 2019 Sep;15(9):889-899. doi: 10.1038/s41589-019-0336-0. Epub 2019 Aug 19.

PMID:
31427817
3.

The late stage of COPI vesicle fission requires shorter forms of phosphatidic acid and diacylglycerol.

Park SY, Yang JS, Li Z, Deng P, Zhu X, Young D, Ericsson M, Andringa RLH, Minnaard AJ, Zhu C, Sun F, Moody DB, Morris AJ, Fan J, Hsu VW.

Nat Commun. 2019 Jul 30;10(1):3409. doi: 10.1038/s41467-019-11324-4.

4.

Total Synthesis of an Immunogenic Trehalose Phospholipid from Salmonella Typhi and Elucidation of Its sn-Regiochemistry by Mass Spectrometry.

Mishra VK, Buter J, Blevins MS, Witte MD, Van Rhijn I, Moody DB, Brodbelt JS, Minnaard AJ.

Org Lett. 2019 Jul 5;21(13):5126-5131. doi: 10.1021/acs.orglett.9b01725. Epub 2019 Jun 20.

5.

1,8-diiodooctane acts as a photo-acid in organic solar cells.

Doumon NY, Wang G, Qiu X, Minnaard AJ, Chiechi RC, Koster LJA.

Sci Rep. 2019 Mar 13;9(1):4350. doi: 10.1038/s41598-019-40948-1.

6.

Discovery of Salmonella trehalose phospholipids reveals functional convergence with mycobacteria.

Reinink P, Buter J, Mishra VK, Ishikawa E, Cheng TY, Willemsen PTJ, Porwollik S, Brennan PJ, Heinz E, Mayfield JA, Dougan G, van Els CA, Cerundolo V, Napolitani G, Yamasaki S, Minnaard AJ, McClelland M, Moody DB, Van Rhijn I.

J Exp Med. 2019 Apr 1;216(4):757-771. doi: 10.1084/jem.20181812. Epub 2019 Feb 25.

7.

Lugdunomycin, an Angucycline-Derived Molecule with Unprecedented Chemical Architecture.

Wu C, van der Heul HU, Melnik AV, Lübben J, Dorrestein PC, Minnaard AJ, Choi YH, van Wezel GP.

Angew Chem Int Ed Engl. 2019 Feb 25;58(9):2809-2814. doi: 10.1002/anie.201814581. Epub 2019 Jan 29.

8.

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.

Shahine A, Reinink P, Reijneveld JF, Gras S, Holzheimer M, Cheng TY, Minnaard AJ, Altman JD, Lenz S, Prandi J, Kubler-Kielb J, Moody DB, Rossjohn J, Van Rhijn I.

Nat Commun. 2019 Jan 4;10(1):56. doi: 10.1038/s41467-018-07898-0.

9.

Regioselective Manipulation of GlcNAc Provides Allosamine, Lividosamine, and Related Compounds.

Zhang J, Eisink NNHM, Witte MD, Minnaard AJ.

J Org Chem. 2019 Jan 18;84(2):516-525. doi: 10.1021/acs.joc.8b01949. Epub 2019 Jan 2.

10.

Converting Escherichia coli into an archaebacterium with a hybrid heterochiral membrane.

Caforio A, Siliakus MF, Exterkate M, Jain S, Jumde VR, Andringa RLH, Kengen SWM, Minnaard AJ, Driessen AJM, van der Oost J.

Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3704-3709. doi: 10.1073/pnas.1721604115. Epub 2018 Mar 19.

11.

CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis.

James CA, Yu KKQ, Gilleron M, Prandi J, Yedulla VR, Moleda ZZ, Diamanti E, Khan M, Aggarwal VK, Reijneveld JF, Reinink P, Lenz S, Emerson RO, Scriba TJ, Souter MNT, Godfrey DI, Pellicci DG, Moody DB, Minnaard AJ, Seshadri C, Van Rhijn I.

Cell Chem Biol. 2018 Apr 19;25(4):392-402.e14. doi: 10.1016/j.chembiol.2018.01.006. Epub 2018 Feb 1.

12.

Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines.

Schröder SP, van de Sande JW, Kallemeijn WW, Kuo CL, Artola M, van Rooden EJ, Jiang J, Beenakker TJM, Florea BI, Offen WA, Davies GJ, Minnaard AJ, Aerts JMFG, Codée JDC, van der Marel GA, Overkleeft HS.

Chem Commun (Camb). 2017 Nov 21;53(93):12528-12531. doi: 10.1039/c7cc07730k.

PMID:
29116266
13.

CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails.

Van Rhijn I, Iwany SK, Fodran P, Cheng TY, Gapin L, Minnaard AJ, Moody DB.

Eur J Immunol. 2017 Sep;47(9):1525-1534. doi: 10.1002/eji.201747062. Epub 2017 Jul 31.

14.

Steering Self-Assembly of Amphiphilic Molecular Nanostructures via Halogen Exchange.

Kriete B, Bondarenko AS, Jumde VR, Franken LE, Minnaard AJ, Jansen TLC, Knoester J, Pshenichnikov MS.

J Phys Chem Lett. 2017 Jul 6;8(13):2895-2901. doi: 10.1021/acs.jpclett.7b00967. Epub 2017 Jun 14.

15.

Site-selective carbon-carbon bond formation in unprotected monosaccharides using photoredox catalysis.

Wan ICS, Witte MD, Minnaard AJ.

Chem Commun (Camb). 2017 May 2;53(36):4926-4929. doi: 10.1039/c7cc01416c.

PMID:
28425550
16.

Regioselective Carbohydrate Oxidations: A Nuclear Magnetic Resonance (NMR) Study on Selectivity, Rate, and Side-Product Formation.

Eisink NN, Witte MD, Minnaard AJ.

ACS Catal. 2017 Feb 3;7(2):1438-1445. doi: 10.1021/acscatal.6b03459. Epub 2017 Jan 18.

17.

C3 Epimerization of Glucose, via Regioselective Oxidation and Reduction.

Jumde VR, Eisink NN, Witte MD, Minnaard AJ.

J Org Chem. 2016 Nov 18;81(22):11439-11443. Epub 2016 Oct 28.

PMID:
27755870
18.

Stereoselective Synthesis of 1-Tuberculosinyl Adenosine; a Virulence Factor of Mycobacterium tuberculosis.

Buter J, Heijnen D, Wan IC, Bickelhaupt FM, Young DC, Otten E, Moody DB, Minnaard AJ.

J Org Chem. 2016 Aug 5;81(15):6686-96. doi: 10.1021/acs.joc.6b01332. Epub 2016 Jul 26.

19.

Regioselective oxidation of unprotected 1,4 linked glucans.

Eisink NN, Lohse J, Witte MD, Minnaard AJ.

Org Biomol Chem. 2016 Jun 7;14(21):4859-64. doi: 10.1039/c6ob00608f. Epub 2016 May 9.

PMID:
27159790
20.

Palladium-Catalyzed, tert-Butyllithium-Mediated Dimerization of Aryl Halides and Its Application in the Atropselective Total Synthesis of Mastigophorene A.

Buter J, Heijnen D, Vila C, Hornillos V, Otten E, Giannerini M, Minnaard AJ, Feringa BL.

Angew Chem Int Ed Engl. 2016 Mar 7;55(11):3620-4. doi: 10.1002/anie.201510328. Epub 2016 Feb 16.

PMID:
26878822
21.

Deuteration enhances catalyst lifetime in palladium-catalysed alcohol oxidation.

Armenise N, Tahiri N, Eisink NN, Denis M, Jäger M, De Vries JG, Witte MD, Minnaard AJ.

Chem Commun (Camb). 2016 Feb 4;52(10):2189-91. doi: 10.1039/c5cc08588h.

PMID:
26725590
22.

Characterization of phthiocerol and phthiodiolone dimycocerosate esters of M. tuberculosis by multiple-stage linear ion-trap MS.

Flentie KN, Stallings CL, Turk J, Minnaard AJ, Hsu FF.

J Lipid Res. 2016 Jan;57(1):142-55. doi: 10.1194/jlr.D063735. Epub 2015 Nov 16.

23.

Regioselective modification of unprotected glycosides.

Jäger M, Minnaard AJ.

Chem Commun (Camb). 2016 Jan 14;52(4):656-64. doi: 10.1039/c5cc08199h.

PMID:
26568447
24.

Palladium(0)/NHC-Catalyzed Reductive Heck Reaction of Enones: A Detailed Mechanistic Study.

Raoufmoghaddam S, Mannathan S, Minnaard AJ, de Vries JG, Reek JN.

Chemistry. 2015 Dec 14;21(51):18811-20. doi: 10.1002/chem.201503217. Epub 2015 Nov 12.

PMID:
26561034
25.

Formation of the ether lipids archaetidylglycerol and archaetidylethanolamine in Escherichia coli.

Caforio A, Jain S, Fodran P, Siliakus M, Minnaard AJ, van der Oost J, Driessen AJ.

Biochem J. 2015 Sep 15;470(3):343-55. doi: 10.1042/BJ20150626. Epub 2015 Jul 20.

PMID:
26195826
26.

In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection.

Young DC, Layre E, Pan SJ, Tapley A, Adamson J, Seshadri C, Wu Z, Buter J, Minnaard AJ, Coscolla M, Gagneux S, Copin R, Ernst JD, Bishai WR, Snider BB, Moody DB.

Chem Biol. 2015 Apr 23;22(4):516-526. doi: 10.1016/j.chembiol.2015.03.015.

27.

Catalytic asymmetric alkylation of acylsilanes.

Rong J, Oost R, Desmarchelier A, Minnaard AJ, Harutyunyan SR.

Angew Chem Int Ed Engl. 2015 Mar 2;54(10):3038-42. doi: 10.1002/anie.201409815. Epub 2014 Nov 17.

PMID:
25403641
28.

Identification of CDP-archaeol synthase, a missing link of ether lipid biosynthesis in Archaea.

Jain S, Caforio A, Fodran P, Lolkema JS, Minnaard AJ, Driessen AJM.

Chem Biol. 2014 Oct 23;21(10):1392-1401. doi: 10.1016/j.chembiol.2014.07.022. Epub 2014 Sep 11.

29.

Total synthesis of (R,R,R)-γ-tocopherol through Cu-catalyzed asymmetric 1,2-addition.

Wu Z, Harutyunyan SR, Minnaard AJ.

Chemistry. 2014 Oct 27;20(44):14250-5. doi: 10.1002/chem.201404458. Epub 2014 Sep 9.

PMID:
25205372
31.

Asymmetric total synthesis of a putative sex pheromone component from the parasitoid wasp Trichogramma turkestanica.

Geerdink D, Buter J, van Beek TA, Minnaard AJ.

Beilstein J Org Chem. 2014 Apr 2;10:761-6. doi: 10.3762/bjoc.10.71. eCollection 2014.

32.

Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c.

Layre E, Lee HJ, Young DC, Martinot AJ, Buter J, Minnaard AJ, Annand JW, Fortune SM, Snider BB, Matsunaga I, Rubin EJ, Alber T, Moody DB.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):2978-83. doi: 10.1073/pnas.1315883111. Epub 2014 Feb 10.

33.

Total synthesis of sulfolipid-1.

Geerdink D, Minnaard AJ.

Chem Commun (Camb). 2014 Mar 4;50(18):2286-8. doi: 10.1039/c3cc48087a. Epub 2014 Jan 17.

PMID:
24441014
34.

Aqueous oxidative Heck reaction as a protein-labeling strategy.

Ourailidou ME, van der Meer JY, Baas BJ, Jeronimus-Stratingh M, Gottumukkala AL, Poelarends GJ, Minnaard AJ, Dekker FJ.

Chembiochem. 2014 Jan 24;15(2):209-12. doi: 10.1002/cbic.201300714. Epub 2013 Dec 20.

35.

A protecting group-free synthesis of the Colorado potato beetle pheromone.

Wu Z, Jäger M, Buter J, Minnaard AJ.

Beilstein J Org Chem. 2013 Nov 6;9:2374-7. doi: 10.3762/bjoc.9.273. eCollection 2013.

36.

Catalytic synthesis of enantiopure mixed diacylglycerols – synthesis of a major M. tuberculosis phospholipid and platelet activating factor.

Fodran P, Minnaard AJ.

Org Biomol Chem. 2013 Sep 25;11(40):6919-28. doi: 10.1039/c3ob41483c.

PMID:
24191360
37.

Catalytic asymmetric alkylation of ketones using organometallic reagents.

Madduri AV, Harutyunyan SR, Minnaard AJ.

Drug Discov Today Technol. 2013 Spring;10(1):e21-7. doi: 10.1016/j.ddtec.2012.10.010. Review.

PMID:
24050226
38.

Catalytic asymmetric total synthesis of (S)-(-)-zearalenone, a novel lipoxygenase inhibitor.

Baggelaar MP, Huang Y, Feringa BL, Dekker FJ, Minnaard AJ.

Bioorg Med Chem. 2013 Sep 1;21(17):5271-4. doi: 10.1016/j.bmc.2013.06.024. Epub 2013 Jun 20.

PMID:
23867388
39.

Synthesis of renewable fine-chemical building blocks by reductive coupling between furfural derivatives and terpenes.

Nicklaus CM, Minnaard AJ, Feringa BL, de Vries JG.

ChemSusChem. 2013 Sep;6(9):1631-5. doi: 10.1002/cssc.201300179. Epub 2013 Jul 15.

PMID:
23857755
40.

Efficient formation of benzylic quaternary centers via palladium catalysis.

Gottumukkala AL, Suljagic J, Matcha K, de Vries JG, Minnaard AJ.

ChemSusChem. 2013 Sep;6(9):1636-9. doi: 10.1002/cssc.201300276. Epub 2013 Jul 2.

PMID:
23821532
41.

Catalytic regioselective oxidation of glycosides.

Jäger M, Hartmann M, de Vries JG, Minnaard AJ.

Angew Chem Int Ed Engl. 2013 Jul 22;52(30):7809-12. doi: 10.1002/anie.201301662. Epub 2013 Jun 18.

PMID:
23780519
42.

Asymmetric amplification in the catalytic enantioselective 1,2-addition of Grignard reagents to enones.

Caprioli F, Madduri AV, Minnaard AJ, Harutyunyan SR.

Chem Commun (Camb). 2013 Jun 18;49(48):5450-2. doi: 10.1039/c3cc41892h. Epub 2013 May 10.

PMID:
23660758
43.

Synthesis and analysis of the all-(S) side chain of phosphomycoketides: a test of NMR predictions for saturated oligoisoprenoid stereoisomers.

Buter J, Yeh EA, Budavich OW, Damodaran K, Minnaard AJ, Curran DP.

J Org Chem. 2013 May 17;78(10):4913-8. doi: 10.1021/jo4005298. Epub 2013 Apr 25.

44.

CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens.

Ly D, Kasmar AG, Cheng TY, de Jong A, Huang S, Roy S, Bhatt A, van Summeren RP, Altman JD, Jacobs WR Jr, Adams EJ, Minnaard AJ, Porcelli SA, Moody DB.

J Exp Med. 2013 Apr 8;210(4):729-41. doi: 10.1084/jem.20120624. Epub 2013 Mar 25.

45.

A novel catalytic asymmetric route towards skipped dienes with a methyl-substituted central stereogenic carbon.

Huang Y, Fañanás-Mastral M, Minnaard AJ, Feringa BL.

Chem Commun (Camb). 2013 Apr 25;49(32):3309-11. doi: 10.1039/c3cc41021h.

PMID:
23503498
46.

Asymmetric synthesis of cyclo-archaeol and β-glucosyl cyclo-archaeol.

Ferrer C, Fodran P, Barroso S, Gibson R, Hopmans EC, Damsté JS, Schouten S, Minnaard AJ.

Org Biomol Chem. 2013 Apr 21;11(15):2482-92. doi: 10.1039/c3ob27277j. Epub 2013 Feb 26.

PMID:
23440078
47.

Total synthesis of (-)-doliculide, structure-activity relationship studies and its binding to F-actin.

Matcha K, Madduri AV, Roy S, Ziegler S, Waldmann H, Hirsch AK, Minnaard AJ.

Chembiochem. 2012 Nov 26;13(17):2537-48. doi: 10.1002/cbic.201200512. Epub 2012 Nov 5.

PMID:
23129522
48.

Total synthesis of the triglycosyl phenolic glycolipid PGL-tb1 from Mycobacterium tuberculosis.

Barroso S, Castelli R, Baggelaar MP, Geerdink D, ter Horst B, Casas-Arce E, Overkleeft HS, van der Marel GA, Codée JD, Minnaard AJ.

Angew Chem Int Ed Engl. 2012 Nov 19;51(47):11774-7. doi: 10.1002/anie.201206221. Epub 2012 Oct 19. No abstract available.

PMID:
23086739
49.

Mutual influence of backbone proline substitution and lipophilic tail character on the biological activity of simplified analogues of caspofungin.

Mulder MP, Fodran P, Kemmink J, Breukink EJ, Kruijtzer JA, Minnaard AJ, Liskamp RM.

Org Biomol Chem. 2012 Oct 7;10(37):7491-502. doi: 10.1039/c2ob25951f.

PMID:
22878559
50.

Palladium-catalyzed asymmetric quaternary stereocenter formation.

Gottumukkala AL, Matcha K, Lutz M, de Vries JG, Minnaard AJ.

Chemistry. 2012 May 29;18(22):6907-14. doi: 10.1002/chem.201200694. Epub 2012 Apr 24.

PMID:
22532469

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