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Items: 1 to 50 of 71

1.

A Bimolecular Multicellular Complementation System for the Detection of Syncytium Formation: A New Methodology for the Identification of Nipah Virus Entry Inhibitors.

García-Murria MJ, Expósito-Domínguez N, Duart G, Mingarro I, Martinez-Gil L.

Viruses. 2019 Mar 7;11(3). pii: E229. doi: 10.3390/v11030229.

2.

Transmembrane but not soluble helices fold inside the ribosome tunnel.

Bañó-Polo M, Baeza-Delgado C, Tamborero S, Hazel A, Grau B, Nilsson I, Whitley P, Gumbart JC, von Heijne G, Mingarro I.

Nat Commun. 2018 Dec 7;9(1):5246. doi: 10.1038/s41467-018-07554-7.

3.

Characterization of the inner membrane protein BB0173 from Borrelia burgdorferi.

Brock CM, Bañó-Polo M, Garcia-Murria MJ, Mingarro I, Esteve-Gasent M.

BMC Microbiol. 2017 Nov 22;17(1):219. doi: 10.1186/s12866-017-1127-y.

4.

Proteomic composition of Nipah virus-like particles.

Vera-Velasco NM, García-Murria MJ, Sánchez Del Pino MM, Mingarro I, Martinez-Gil L.

J Proteomics. 2018 Feb 10;172:190-200. doi: 10.1016/j.jprot.2017.10.012. Epub 2017 Oct 29.

PMID:
29092793
5.

The role of hydrophobic matching on transmembrane helix packing in cells.

Grau B, Javanainen M, García-Murria MJ, Kulig W, Vattulainen I, Mingarro I, Martínez-Gil L.

Cell Stress. 2017 Nov 2;1(2):90-106. doi: 10.15698/cst2017.11.111.

6.

Exploring the Human-Nipah Virus Protein-Protein Interactome.

Martinez-Gil L, Vera-Velasco NM, Mingarro I.

J Virol. 2017 Nov 14;91(23). pii: e01461-17. doi: 10.1128/JVI.01461-17. Print 2017 Dec 1.

7.

N-Linked Glycosylation of the p24 Family Protein p24δ5 Modulates Retrograde Golgi-to-ER Transport of K/HDEL Ligands in Arabidopsis.

Pastor-Cantizano N, García-Murria MJ, Bernat-Silvestre C, Marcote MJ, Mingarro I, Aniento F.

Mol Plant. 2017 Aug 7;10(8):1095-1106. doi: 10.1016/j.molp.2017.07.007. Epub 2017 Jul 19.

8.

Membrane insertion and topology of the translocon-associated protein (TRAP) gamma subunit.

Bañó-Polo M, Martínez-Garay CA, Grau B, Martínez-Gil L, Mingarro I.

Biochim Biophys Acta Biomembr. 2017 May;1859(5):903-909. doi: 10.1016/j.bbamem.2017.01.027. Epub 2017 Jan 26.

9.

Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes.

Andreu-Fernández V, Sancho M, Genovés A, Lucendo E, Todt F, Lauterwasser J, Funk K, Jahreis G, Pérez-Payá E, Mingarro I, Edlich F, Orzáez M.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):310-315. doi: 10.1073/pnas.1612322114. Epub 2016 Dec 27. Erratum in: Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1574.

10.

NMR Investigation of Structures of G-protein Coupled Receptor Folding Intermediates.

Poms M, Ansorge P, Martinez-Gil L, Jurt S, Gottstein D, Fracchiolla KE, Cohen LS, Güntert P, Mingarro I, Naider F, Zerbe O.

J Biol Chem. 2016 Dec 30;291(53):27170-27186. doi: 10.1074/jbc.M116.740985. Epub 2016 Nov 18.

11.

The C-terminal Domains of Apoptotic BH3-only Proteins Mediate Their Insertion into Distinct Biological Membranes.

Andreu-Fernández V, García-Murria MJ, Bañó-Polo M, Martin J, Monticelli L, Orzáez M, Mingarro I.

J Biol Chem. 2016 Nov 25;291(48):25207-25216. Epub 2016 Oct 7.

12.

Biological insertion of computationally designed short transmembrane segments.

Baeza-Delgado C, von Heijne G, Marti-Renom MA, Mingarro I.

Sci Rep. 2016 Mar 18;6:23397. doi: 10.1038/srep23397.

13.

The ER-Membrane Transport System Is Critical for Intercellular Trafficking of the NSm Movement Protein and Tomato Spotted Wilt Tospovirus.

Feng Z, Xue F, Xu M, Chen X, Zhao W, Garcia-Murria MJ, Mingarro I, Liu Y, Huang Y, Jiang L, Zhu M, Tao X.

PLoS Pathog. 2016 Feb 10;12(2):e1005443. doi: 10.1371/journal.ppat.1005443. eCollection 2016 Feb.

14.

Human Peroxin PEX3 Is Co-translationally Integrated into the ER and Exits the ER in Budding Vesicles.

Mayerhofer PU, Bañó-Polo M, Mingarro I, Johnson AE.

Traffic. 2016 Feb;17(2):117-30. doi: 10.1111/tra.12350. Epub 2015 Dec 21.

15.

Viroporins, Examples of the Two-Stage Membrane Protein Folding Model.

Martinez-Gil L, Mingarro I.

Viruses. 2015 Jun 26;7(7):3462-82. doi: 10.3390/v7072781. Review.

16.

Molecular and topological membrane folding determinants of transient receptor potential vanilloid 2 channel.

Doñate-Macian P, Bañó-Polo M, Vazquez-Ibar JL, Mingarro I, Perálvarez-Marín A.

Biochem Biophys Res Commun. 2015 Jul 3;462(3):221-6. doi: 10.1016/j.bbrc.2015.04.120. Epub 2015 May 5.

PMID:
25956061
17.

Stitching proteins into membranes, not sew simple.

Whitley P, Mingarro I.

Biol Chem. 2014 Dec;395(12):1417-24. doi: 10.1515/hsz-2014-0205. Review.

PMID:
25153236
18.

Peptides derived from the transmembrane domain of Bcl-2 proteins as potential mitochondrial priming tools.

Andreu-Fernández V, Genoves A, Lee TH, Stellato M, Lucantoni F, Orzáez M, Mingarro I, Aguilar MI, Pérez-Payá E.

ACS Chem Biol. 2014 Aug 15;9(8):1799-811. doi: 10.1021/cb5002679. Epub 2014 Jun 17.

PMID:
24905660
19.

The Tobacco mosaic virus movement protein associates with but does not integrate into biological membranes.

Peiró A, Martínez-Gil L, Tamborero S, Pallás V, Sánchez-Navarro JA, Mingarro I.

J Virol. 2014 Mar;88(5):3016-26. doi: 10.1128/JVI.03648-13. Epub 2013 Dec 26.

20.

A transmembrane serine residue in the Rot1 protein is essential for yeast cell viability.

Martínez-Garay CA, Juanes MA, Igual JC, Mingarro I, Bañó MC.

Biochem J. 2014 Mar 1;458(2):239-49. doi: 10.1042/BJ20131306.

PMID:
24303792
21.

The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild.

Prado-Martinez J, Hernando-Herraez I, Lorente-Galdos B, Dabad M, Ramirez O, Baeza-Delgado C, Morcillo-Suarez C, Alkan C, Hormozdiari F, Raineri E, Estellé J, Fernandez-Callejo M, Valles M, Ritscher L, Schöneberg T, de la Calle-Mustienes E, Casillas S, Rubio-Acero R, Melé M, Engelken J, Caceres M, Gomez-Skarmeta JL, Gut M, Bertranpetit J, Gut IG, Abello T, Eichler EE, Mingarro I, Lalueza-Fox C, Navarro A, Marques-Bonet T.

BMC Genomics. 2013 May 31;14:363. doi: 10.1186/1471-2164-14-363.

22.

BB0172, a Borrelia burgdorferi outer membrane protein that binds integrin α3β1.

Wood E, Tamborero S, Mingarro I, Esteve-Gassent MD.

J Bacteriol. 2013 Aug;195(15):3320-30. doi: 10.1128/JB.00187-13. Epub 2013 May 17.

23.

Charge pair interactions in transmembrane helices and turn propensity of the connecting sequence promote helical hairpin insertion.

Bañó-Polo M, Martínez-Gil L, Wallner B, Nieva JL, Elofsson A, Mingarro I.

J Mol Biol. 2013 Feb 22;425(4):830-40. doi: 10.1016/j.jmb.2012.12.001. Epub 2012 Dec 7.

PMID:
23228331
24.

Polar/Ionizable residues in transmembrane segments: effects on helix-helix packing.

Bañó-Polo M, Baeza-Delgado C, Orzáez M, Marti-Renom MA, Abad C, Mingarro I.

PLoS One. 2012;7(9):e44263. doi: 10.1371/journal.pone.0044263. Epub 2012 Sep 12.

25.

Structure-based statistical analysis of transmembrane helices.

Baeza-Delgado C, Marti-Renom MA, Mingarro I.

Eur Biophys J. 2013 Mar;42(2-3):199-207. doi: 10.1007/s00249-012-0813-9. Epub 2012 May 16.

PMID:
22588483
26.

Interfacial behavior of recombinant forms of human pulmonary surfactant protein SP-C.

Lukovic D, Cruz A, Gonzalez-Horta A, Almlen A, Curstedt T, Mingarro I, Pérez-Gil J.

Langmuir. 2012 May 22;28(20):7811-25. doi: 10.1021/la301134v. Epub 2012 May 10.

PMID:
22530695
27.

Membrane integration of poliovirus 2B viroporin.

Martínez-Gil L, Bañó-Polo M, Redondo N, Sánchez-Martínez S, Nieva JL, Carrasco L, Mingarro I.

J Virol. 2011 Nov;85(21):11315-24. doi: 10.1128/JVI.05421-11. Epub 2011 Aug 10.

28.

Membrane protein integration into the endoplasmic reticulum.

Martínez-Gil L, Saurí A, Marti-Renom MA, Mingarro I.

FEBS J. 2011 Oct;278(20):3846-58. doi: 10.1111/j.1742-4658.2011.08185.x. Epub 2011 Jun 13. Review.

29.

Membrane insertion and topology of the translocating chain-associating membrane protein (TRAM).

Tamborero S, Vilar M, Martínez-Gil L, Johnson AE, Mingarro I.

J Mol Biol. 2011 Mar 4;406(4):571-82. doi: 10.1016/j.jmb.2011.01.009. Epub 2011 Jan 13.

PMID:
21237175
30.

N-glycosylation efficiency is determined by the distance to the C-terminus and the amino acid preceding an Asn-Ser-Thr sequon.

Bañó-Polo M, Baldin F, Tamborero S, Marti-Renom MA, Mingarro I.

Protein Sci. 2011 Jan;20(1):179-86. doi: 10.1002/pro.551.

31.

Palmitoylation of pulmonary surfactant protein SP-C is critical for its functional cooperation with SP-B to sustain compression/expansion dynamics in cholesterol-containing surfactant films.

Baumgart F, Ospina OL, Mingarro I, Rodríguez-Crespo I, Pérez-Gil J.

Biophys J. 2010 Nov 17;99(10):3234-43. doi: 10.1016/j.bpj.2010.08.070.

32.

Membrane insertion and biogenesis of the Turnip crinkle virus p9 movement protein.

Martínez-Gil L, Johnson AE, Mingarro I.

J Virol. 2010 Jun;84(11):5520-7. doi: 10.1128/JVI.00125-10. Epub 2010 Mar 24.

33.

Membrane topology of gp41 and amyloid precursor protein: interfering transmembrane interactions as potential targets for HIV and Alzheimer treatment.

Abad C, Martínez-Gil L, Tamborero S, Mingarro I.

Biochim Biophys Acta. 2009 Oct;1788(10):2132-41. doi: 10.1016/j.bbamem.2009.07.008. Epub 2009 Jul 18. Review.

34.

Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers.

Vilar M, Charalampopoulos I, Kenchappa RS, Simi A, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman WJ, Schiavo G, Bastiaens PI, Verveer PJ, Carter BD, Ibáñez CF.

Neuron. 2009 Apr 16;62(1):72-83. doi: 10.1016/j.neuron.2009.02.020.

35.

Plant virus cell-to-cell movement is not dependent on the transmembrane disposition of its movement protein.

Martínez-Gil L, Sánchez-Navarro JA, Cruz A, Pallás V, Pérez-Gil J, Mingarro I.

J Virol. 2009 Jun;83(11):5535-43. doi: 10.1128/JVI.00393-09. Epub 2009 Mar 25.

36.

Viral membrane protein topology is dictated by multiple determinants in its sequence.

Saurí A, Tamborero S, Martínez-Gil L, Johnson AE, Mingarro I.

J Mol Biol. 2009 Mar 20;387(1):113-28. doi: 10.1016/j.jmb.2009.01.063. Epub 2009 Feb 4.

PMID:
19302797
37.

The surfactant peptide KL4 sequence is inserted with a transmembrane orientation into the endoplasmic reticulum membrane.

Martínez-Gil L, Pérez-Gil J, Mingarro I.

Biophys J. 2008 Sep 15;95(6):L36-8. doi: 10.1529/biophysj.108.138602. Epub 2008 Jul 11.

38.

Synthetic pulmonary surfactant preparations: new developments and future trends.

Mingarro I, Lukovic D, Vilar M, Pérez-Gil J.

Curr Med Chem. 2008;15(4):393-403. Review.

PMID:
18288994
39.

Membrane insertion and topology of the p7B movement protein of Melon Necrotic Spot Virus (MNSV).

Martínez-Gil L, Saurí A, Vilar M, Pallás V, Mingarro I.

Virology. 2007 Oct 25;367(2):348-57. Epub 2007 Jul 3.

40.

Sec61alpha and TRAM are sequentially adjacent to a nascent viral membrane protein during its ER integration.

Saurí A, McCormick PJ, Johnson AE, Mingarro I.

J Mol Biol. 2007 Feb 16;366(2):366-74. Epub 2006 Nov 18.

PMID:
17169373
41.

RNA-binding properties and membrane insertion of Melon necrotic spot virus (MNSV) double gene block movement proteins.

Navarro JA, Genovés A, Climent J, Saurí A, Martínez-Gil L, Mingarro I, Pallás V.

Virology. 2006 Dec 5-20;356(1-2):57-67. Epub 2006 Sep 1.

42.

Hexapeptides that interfere with HIV-1 fusion peptide activity in liposomes block GP41-mediated membrane fusion.

Gómara MJ, Lorizate M, Huarte N, Mingarro I, Perez-Payá E, Nieva JL.

FEBS Lett. 2006 May 15;580(11):2561-6. Epub 2006 Apr 21.

43.

Production and characterisation of recombinant forms of human pulmonary surfactant protein C (SP-C): Structure and surface activity.

Lukovic D, Plasencia I, Taberner FJ, Salgado J, Calvete JJ, Pérez-Gil J, Mingarro I.

Biochim Biophys Acta. 2006 Apr;1758(4):509-18. Epub 2006 Mar 31.

44.

Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores.

García-Sáez AJ, Coraiola M, Serra MD, Mingarro I, Müller P, Salgado J.

FEBS J. 2006 Mar;273(5):971-81.

45.

Small molecule inhibitors of Apaf-1-related caspase- 3/-9 activation that control mitochondrial-dependent apoptosis.

Malet G, Martín AG, Orzáez M, Vicent MJ, Masip I, Sanclimens G, Ferrer-Montiel A, Mingarro I, Messeguer A, Fearnhead HO, Pérez-Payá E.

Cell Death Differ. 2006 Sep;13(9):1523-32. Epub 2005 Dec 9.

46.

Transient structural ordering of the RNA-binding domain of carnation mottle virus p7 movement protein modulates nucleic acid binding.

Vilar M, Saurí A, Marcos JF, Mingarro I, Pérez-Payá E.

Chembiochem. 2005 Aug;6(8):1391-6.

PMID:
16003802
47.
48.
49.

Peptides derived from apoptotic Bax and Bid reproduce the poration activity of the parent full-length proteins.

García-Sáez AJ, Coraiola M, Dalla Serra M, Mingarro I, Menestrina G, Salgado J.

Biophys J. 2005 Jun;88(6):3976-90. Epub 2005 Mar 18.

50.

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