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Items: 1 to 50 of 281

1.

HO-1 downregulation favors BRAFV600 melanoma cell death induced by Vemurafenib/PLX4032 and increases NK recognition.

Furfaro AL, Ottonello S, Loi G, Cossu I, Piras S, Spagnolo F, Queirolo P, Marinari UM, Moretta L, Pronzato MA, Mingari MC, Pietra G, Mariapaola N.

Int J Cancer. 2019 Aug 3. doi: 10.1002/ijc.32611. [Epub ahead of print]

PMID:
31376303
2.

Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation.

Pende D, Falco M, Vitale M, Cantoni C, Vitale C, Munari E, Bertaina A, Moretta F, Del Zotto G, Pietra G, Mingari MC, Locatelli F, Moretta L.

Front Immunol. 2019 May 28;10:1179. doi: 10.3389/fimmu.2019.01179. eCollection 2019. Review.

3.

NKp44-NKp44 Ligand Interactions in the Regulation of Natural Killer Cells and Other Innate Lymphoid Cells in Humans.

Parodi M, Favoreel H, Candiano G, Gaggero S, Sivori S, Mingari MC, Moretta L, Vitale M, Cantoni C.

Front Immunol. 2019 Apr 9;10:719. doi: 10.3389/fimmu.2019.00719. eCollection 2019. Review.

4.

Presence of innate lymphoid cells in pleural effusions of primary and metastatic tumors: Functional analysis and expression of PD-1 receptor.

Tumino N, Martini S, Munari E, Scordamaglia F, Besi F, Mariotti FR, Bogina G, Mingari MC, Vacca P, Moretta L.

Int J Cancer. 2019 Sep 15;145(6):1660-1668. doi: 10.1002/ijc.32262. Epub 2019 Mar 26.

PMID:
30856277
5.

Natural killer cells: From surface receptors to the cure of high-risk leukemia (Ceppellini Lecture).

Falco M, Pende D, Munari E, Vacca P, Mingari MC, Moretta L.

HLA. 2019 Apr;93(4):185-194. doi: 10.1111/tan.13509. Review.

PMID:
30828978
6.

Heterogeneity of NK Cells and Other Innate Lymphoid Cells in Human and Murine Decidua.

Vacca P, Chiossone L, Mingari MC, Moretta L.

Front Immunol. 2019 Feb 8;10:170. doi: 10.3389/fimmu.2019.00170. eCollection 2019. Review.

7.

Human NK cells: surface receptors, inhibitory checkpoints, and translational applications.

Sivori S, Vacca P, Del Zotto G, Munari E, Mingari MC, Moretta L.

Cell Mol Immunol. 2019 May;16(5):430-441. doi: 10.1038/s41423-019-0206-4. Epub 2019 Feb 18. Review.

PMID:
30778167
8.

PD-1 is expressed by and regulates human group 3 innate lymphoid cells in human decidua.

Vacca P, Pesce S, Greppi M, Fulcheri E, Munari E, Olive D, Mingari MC, Moretta A, Moretta L, Marcenaro E.

Mucosal Immunol. 2019 May;12(3):624-631. doi: 10.1038/s41385-019-0141-9. Epub 2019 Feb 12.

PMID:
30755717
9.

Influence of Vitamin D in Advanced Non-Small Cell Lung Cancer Patients Treated with Nivolumab.

Cusato J, Genova C, Tomasello C, Carrega P, Ottonello S, Pietra G, Mingari MC, Cossu I, Rijavec E, Leggieri A, Di Perri G, Dal Bello MG, Coco S, Boccardo S, Ferlazzo G, Grossi F, D'Avolio A.

Cancers (Basel). 2019 Jan 21;11(1). pii: E125. doi: 10.3390/cancers11010125.

10.

Correction: PD-L1 expression heterogeneity in non-small cell lung cancer: evaluation of small biopsies reliability.

Munari E, Zamboni G, Marconi M, Sommaggio M, Brunelli M, Martignoni G, Netto GJ, Moretta F, Mingari MC, Salgarello M, Terzi A, Picece V, Pomari C, Lunardi G, Cavazza A, Rossi G, Moretta L, Bogina G.

Oncotarget. 2018 Dec 11;9(97):37077. doi: 10.18632/oncotarget.26475. eCollection 2018 Dec 11.

11.

Immune Checkpoint Inhibitors: Anti-NKG2A Antibodies on Board.

Mingari MC, Pietra G, Moretta L.

Trends Immunol. 2019 Feb;40(2):83-85. doi: 10.1016/j.it.2018.12.009. Epub 2019 Jan 1.

PMID:
30609967
12.

Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration.

Parodi M, Raggi F, Cangelosi D, Manzini C, Balsamo M, Blengio F, Eva A, Varesio L, Pietra G, Moretta L, Mingari MC, Vitale M, Bosco MC.

Front Immunol. 2018 Oct 16;9:2358. doi: 10.3389/fimmu.2018.02358. eCollection 2018.

13.

Human natural killer cells and other innate lymphoid cells in cancer: Friends or foes?

Vacca P, Munari E, Tumino N, Moretta F, Pietra G, Vitale M, Del Zotto G, Mariotti FR, Mingari MC, Moretta L.

Immunol Lett. 2018 Sep;201:14-19. doi: 10.1016/j.imlet.2018.11.004. Epub 2018 Nov 12. Review.

14.

Effect of Tyrosin Kinase Inhibitors on NK Cell and ILC3 Development and Function.

Damele L, Montaldo E, Moretta L, Vitale C, Mingari MC.

Front Immunol. 2018 Oct 23;9:2433. doi: 10.3389/fimmu.2018.02433. eCollection 2018.

15.

Molecular definition of group 1 innate lymphoid cells in the mouse uterus.

Filipovic I, Chiossone L, Vacca P, Hamilton RS, Ingegnere T, Doisne JM, Hawkes DA, Mingari MC, Sharkey AM, Moretta L, Colucci F.

Nat Commun. 2018 Oct 29;9(1):4492. doi: 10.1038/s41467-018-06918-3.

16.

Human Innate Lymphoid Cells: Their Functional and Cellular Interactions in Decidua.

Vacca P, Vitale C, Munari E, Cassatella MA, Mingari MC, Moretta L.

Front Immunol. 2018 Aug 14;9:1897. doi: 10.3389/fimmu.2018.01897. eCollection 2018. Review.

17.

PD-L1 expression comparison between primary and relapsed non-small cell lung carcinoma using whole sections and clone SP263.

Munari E, Zamboni G, Lunardi G, Marconi M, Sommaggio M, Brunelli M, Martignoni G, Netto GJ, Hoque MO, Moretta F, Mingari MC, Pegoraro MC, Mariotti FR, Vacca P, Moretta L, Bogina G.

Oncotarget. 2018 Jul 13;9(54):30465-30471. doi: 10.18632/oncotarget.25770. eCollection 2018 Jul 13.

18.

NK-cell Editing Mediates Epithelial-to-Mesenchymal Transition via Phenotypic and Proteomic Changes in Melanoma Cell Lines.

Huergo-Zapico L, Parodi M, Cantoni C, Lavarello C, Fernández-Martínez JL, Petretto A, DeAndrés-Galiana EJ, Balsamo M, López-Soto A, Pietra G, Bugatti M, Munari E, Marconi M, Mingari MC, Vermi W, Moretta L, González S, Vitale M.

Cancer Res. 2018 Jul 15;78(14):3913-3925. doi: 10.1158/0008-5472.CAN-17-1891. Epub 2018 May 11.

19.

PD-L1 Expression Heterogeneity in Non-Small Cell Lung Cancer: Defining Criteria for Harmonization between Biopsy Specimens and Whole Sections.

Munari E, Zamboni G, Lunardi G, Marchionni L, Marconi M, Sommaggio M, Brunelli M, Martignoni G, Netto GJ, Hoque MO, Moretta F, Mingari MC, Pegoraro MC, Inno A, Paiano S, Terzi A, Cavazza A, Rossi G, Mariotti FR, Vacca P, Moretta L, Bogina G.

J Thorac Oncol. 2018 Aug;13(8):1113-1120. doi: 10.1016/j.jtho.2018.04.017. Epub 2018 Apr 25. Erratum in: J Thorac Oncol. 2019 Apr;14(4):744.

20.

PD-L1 expression heterogeneity in non-small cell lung cancer: evaluation of small biopsies reliability.

Munari E, Zamboni G, Marconi M, Sommaggio M, Brunelli M, Martignoni G, Netto GJ, Moretta F, Mingari MC, Salgarello M, Terzi A, Picece V, Pomari C, Lunardi G, Cavazza A, Rossi G, Moretta L, Bogina G.

Oncotarget. 2017 Oct 4;8(52):90123-90131. doi: 10.18632/oncotarget.21485. eCollection 2017 Oct 27. Erratum in: Oncotarget. 2018 Dec 11;9(97):37077.

21.

A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors.

Sullivan LC, Walpole NG, Farenc C, Pietra G, Sum MJW, Clements CS, Lee EJ, Beddoe T, Falco M, Mingari MC, Moretta L, Gras S, Rossjohn J, Brooks AG.

J Biol Chem. 2017 Dec 22;292(51):21149-21158. doi: 10.1074/jbc.M117.807719. Epub 2017 Sep 25.

22.

IL15 induces a potent antitumor activity in NK cells isolated from malignant pleural effusions and overcomes the inhibitory effect of pleural fluid.

Croxatto D, Martini S, Chiossone L, Scordamaglia F, Simonassi CF, Moretta L, Mingari MC, Vacca P.

Oncoimmunology. 2017 Feb 17;6(4):e1293210. doi: 10.1080/2162402X.2017.1293210. eCollection 2017.

23.

Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients.

Meazza R, Falco M, Marcenaro S, Loiacono F, Canevali P, Bellora F, Tuberosa C, Locatelli F, Micalizzi C, Moretta A, Mingari MC, Moretta L, Aricò M, Bottino C, Pende D.

Eur J Immunol. 2017 Jun;47(6):1051-1061. doi: 10.1002/eji.201646885. Epub 2017 May 5.

24.

Markers and function of human NK cells in normal and pathological conditions.

Del Zotto G, Marcenaro E, Vacca P, Sivori S, Pende D, Della Chiesa M, Moretta F, Ingegnere T, Mingari MC, Moretta A, Moretta L.

Cytometry B Clin Cytom. 2017 Mar;92(2):100-114. doi: 10.1002/cyto.b.21508. Epub 2017 Feb 12. Review.

25.

Human innate lymphoid cells.

Montaldo E, Vacca P, Vitale C, Moretta F, Locatelli F, Mingari MC, Moretta L.

Immunol Lett. 2016 Nov;179:2-8. doi: 10.1016/j.imlet.2016.01.007. Epub 2016 Feb 1. Review.

PMID:
26844414
26.

Cytokines can counteract the inhibitory effect of MEK-i on NK-cell function.

Manzini C, Venè R, Cossu I, Gualco M, Zupo S, Dono M, Spagnolo F, Queirolo P, Moretta L, Mingari MC, Pietra G.

Oncotarget. 2016 Sep 20;7(38):60858-60871. doi: 10.18632/oncotarget.11504.

27.

NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

Cantoni C, Huergo-Zapico L, Parodi M, Pedrazzi M, Mingari MC, Moretta A, Sparatore B, Gonzalez S, Olive D, Bottino C, Castriconi R, Vitale M.

J Immunol Res. 2016;2016:4684268. doi: 10.1155/2016/4684268. Epub 2016 May 12. Review.

28.

NK Cells and Other Innate Lymphoid Cells in Hematopoietic Stem Cell Transplantation.

Vacca P, Montaldo E, Croxatto D, Moretta F, Bertaina A, Vitale C, Locatelli F, Mingari MC, Moretta L.

Front Immunol. 2016 May 18;7:188. doi: 10.3389/fimmu.2016.00188. eCollection 2016. Review.

29.

Human NK cells: From surface receptors to clinical applications.

Moretta L, Pietra G, Vacca P, Pende D, Moretta F, Bertaina A, Mingari MC, Locatelli F, Moretta A.

Immunol Lett. 2016 Oct;178:15-9. doi: 10.1016/j.imlet.2016.05.007. Epub 2016 May 13.

PMID:
27185471
30.

Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition.

Saunders PM, Pymm P, Pietra G, Hughes VA, Hitchen C, O'Connor GM, Loiacono F, Widjaja J, Price DA, Falco M, Mingari MC, Moretta L, McVicar DW, Rossjohn J, Brooks AG, Vivian JP.

J Exp Med. 2016 May 2;213(5):791-807. doi: 10.1084/jem.20152023. Epub 2016 Apr 4.

31.

Group 3 innate lymphoid cells regulate neutrophil migration and function in human decidua.

Croxatto D, Micheletti A, Montaldo E, Orecchia P, Loiacono F, Canegallo F, Calzetti F, Fulcheri E, Munari E, Zamò A, Venturini PL, Moretta L, Cassatella MA, Mingari MC, Vacca P.

Mucosal Immunol. 2016 Nov;9(6):1372-1383. doi: 10.1038/mi.2016.10. Epub 2016 Feb 24.

PMID:
26906405
32.

The generation of human innate lymphoid cells is influenced by the source of hematopoietic stem cells and by the use of G-CSF.

Moretta F, Petronelli F, Lucarelli B, Pitisci A, Bertaina A, Locatelli F, Mingari MC, Moretta L, Montaldo E.

Eur J Immunol. 2016 May;46(5):1271-8. doi: 10.1002/eji.201546079. Epub 2016 Feb 19.

33.

Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment.

Parodi M, Pedrazzi M, Cantoni C, Averna M, Patrone M, Cavaletto M, Spertino S, Pende D, Balsamo M, Pietra G, Sivori S, Carlomagno S, Mingari MC, Moretta L, Sparatore B, Vitale M.

Oncoimmunology. 2015 May 29;4(12):e1052353. eCollection 2015 Dec.

34.

Targeting Syndecan-1, a molecule implicated in the process of vasculogenic mimicry, enhances the therapeutic efficacy of the L19-IL2 immunocytokine in human melanoma xenografts.

Orecchia P, Conte R, Balza E, Pietra G, Mingari MC, Carnemolla B.

Oncotarget. 2015 Nov 10;6(35):37426-42. doi: 10.18632/oncotarget.6055.

35.

NCR(+)ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures.

Carrega P, Loiacono F, Di Carlo E, Scaramuccia A, Mora M, Conte R, Benelli R, Spaggiari GM, Cantoni C, Campana S, Bonaccorsi I, Morandi B, Truini M, Mingari MC, Moretta L, Ferlazzo G.

Nat Commun. 2015 Sep 23;6:8280. doi: 10.1038/ncomms9280.

PMID:
26395069
36.

A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation.

Morandi F, Morandi B, Horenstein AL, Chillemi A, Quarona V, Zaccarello G, Carrega P, Ferlazzo G, Mingari MC, Moretta L, Pistoia V, Malavasi F.

Oncotarget. 2015 Sep 22;6(28):25602-18. doi: 10.18632/oncotarget.4693.

37.

Role of NK cells in immunotherapy and virotherapy of solid tumors.

Cantoni C, Grauwet K, Pietra G, Parodi M, Mingari MC, Maria AD, Favoreel H, Vitale M.

Immunotherapy. 2015;7(8):861-82. doi: 10.2217/imt.15.53. Epub 2015 Aug 28. Review.

PMID:
26314197
38.

Human natural killer cells: news in the therapy of solid tumors and high-risk leukemias.

Pietra G, Vitale C, Pende D, Bertaina A, Moretta F, Falco M, Vacca P, Montaldo E, Cantoni C, Mingari MC, Moretta A, Locatelli F, Moretta L.

Cancer Immunol Immunother. 2016 Apr;65(4):465-76. doi: 10.1007/s00262-015-1744-y. Epub 2015 Aug 20. Review.

PMID:
26289090
39.

MSC and innate immune cell interactions: A lesson from human decidua.

Vacca P, Montaldo E, Vitale C, Croxatto D, Moretta L, Mingari MC.

Immunol Lett. 2015 Dec;168(2):170-4. doi: 10.1016/j.imlet.2015.05.006. Epub 2015 May 15. Review.

PMID:
25986011
40.

IL-1β inhibits ILC3 while favoring NK-cell maturation of umbilical cord blood CD34(+) precursors.

Ambrosini P, Loiacono F, Conte R, Moretta L, Vitale C, Mingari MC.

Eur J Immunol. 2015 Jul;45(7):2061-71. doi: 10.1002/eji.201445326. Epub 2015 May 12. Erratum in: Eur J Immunol. 2015 Aug;45(8):2420.

41.

Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines.

Caccamo N, Pietra G, Sullivan LC, Brooks AG, Prezzemolo T, La Manna MP, Di Liberto D, Joosten SA, van Meijgaarden KE, Di Carlo P, Titone L, Moretta L, Mingari MC, Ottenhoff TH, Dieli F.

Eur J Immunol. 2015 Apr;45(4):1069-81. doi: 10.1002/eji.201445193. Epub 2015 Feb 17. Erratum in: Eur J Immunol. 2019 Jun;49(6):971.

42.

Unique Eomes(+) NK Cell Subsets Are Present in Uterus and Decidua During Early Pregnancy.

Montaldo E, Vacca P, Chiossone L, Croxatto D, Loiacono F, Martini S, Ferrero S, Walzer T, Moretta L, Mingari MC.

Front Immunol. 2016 Jan 7;6:646. doi: 10.3389/fimmu.2015.00646. eCollection 2015.

43.

Human RORγt(+)CD34(+) cells are lineage-specified progenitors of group 3 RORγt(+) innate lymphoid cells.

Montaldo E, Teixeira-Alves LG, Glatzer T, Durek P, Stervbo U, Hamann W, Babic M, Paclik D, Stölzel K, Gröne J, Lozza L, Juelke K, Matzmohr N, Loiacono F, Petronelli F, Huntington ND, Moretta L, Mingari MC, Romagnani C.

Immunity. 2014 Dec 18;41(6):988-1000. doi: 10.1016/j.immuni.2014.11.010. Epub 2014 Nov 28.

44.

IL-1β-releasing human acute myeloid leukemia blasts modulate natural killer cell differentiation from CD34+ precursors.

Vitale C, Ambrosini P, Montaldo E, Ballerini F, Moretta L, Mingari MC.

Haematologica. 2015 Feb;100(2):e42-5. doi: 10.3324/haematol.2014.110494. Epub 2014 Oct 24. No abstract available.

45.

Human natural killer cells: origin, receptors, function, and clinical applications.

Moretta L, Montaldo E, Vacca P, Del Zotto G, Moretta F, Merli P, Locatelli F, Mingari MC.

Int Arch Allergy Immunol. 2014;164(4):253-64. doi: 10.1159/000365632. Epub 2014 Aug 26. Review.

PMID:
25323661
46.

Identification of diverse innate lymphoid cells in human decidua.

Vacca P, Montaldo E, Croxatto D, Loiacono F, Canegallo F, Venturini PL, Moretta L, Mingari MC.

Mucosal Immunol. 2015 Mar;8(2):254-64. doi: 10.1038/mi.2014.63. Epub 2014 Jul 23.

PMID:
25052762
47.

Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis.

Meazza R, Tuberosa C, Cetica V, Falco M, Parolini S, Grieve S, Griffiths GM, Sieni E, Marcenaro S, Micalizzi C, Montin D, Fagioli F, Moretta A, Mingari MC, Moretta L, Notarangelo LD, Bottino C, Aricò M, Pende D.

J Allergy Clin Immunol. 2014 Dec;134(6):1381-1387.e7. doi: 10.1016/j.jaci.2014.04.043. Epub 2014 Jun 27.

PMID:
24985396
48.

Effect of tumor cells and tumor microenvironment on NK-cell function.

Vitale M, Cantoni C, Pietra G, Mingari MC, Moretta L.

Eur J Immunol. 2014 Jun;44(6):1582-92. doi: 10.1002/eji.201344272. Review.

49.

CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph.

Carrega P, Bonaccorsi I, Di Carlo E, Morandi B, Paul P, Rizzello V, Cipollone G, Navarra G, Mingari MC, Moretta L, Ferlazzo G.

J Immunol. 2014 Apr 15;192(8):3805-15. doi: 10.4049/jimmunol.1301889. Epub 2014 Mar 19.

50.

Human NK cells: from surface receptors to the therapy of leukemias and solid tumors.

Moretta L, Pietra G, Montaldo E, Vacca P, Pende D, Falco M, Del Zotto G, Locatelli F, Moretta A, Mingari MC.

Front Immunol. 2014 Mar 7;5:87. doi: 10.3389/fimmu.2014.00087. eCollection 2014. Review.

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