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Items: 5


CYP3A4 induction in the liver and intestine of PXR/CYP3A-humanized mice: approaches by mass spectrometry imaging and portal blood analysis.

Kobayashi K, Kuze J, Abe S, Takehara S, Minegishi G, Igarashi K, Kitajima S, Kanno J, Yamamoto T, Oshimura M, Kazuki Y.

Mol Pharmacol. 2019 Aug 27. pii: mol.119.117333. doi: 10.1124/mol.119.117333. [Epub ahead of print]


Comparison of the hepatic metabolism of triazolam in wild-type andCyp3a-knockout mice for understanding CYP3A-mediated metabolism inCYP3A-humanised mice in vivo.

Minegishi G, Kazuki Y, Yamasaki Y, Okuya F, Akita H, Oshimura M, Kobayashi K.

Xenobiotica. 2019 Nov;49(11):1303-1310. doi: 10.1080/00498254.2018.1560516. Epub 2019 Jun 14.


Characterization of P-Glycoprotein Humanized Mice Generated by Chromosome Engineering Technology: Its Utility for Prediction of Drug Distribution to the Brain in Humans.

Yamasaki Y, Kobayashi K, Okuya F, Kajitani N, Kazuki K, Abe S, Takehara S, Ito S, Ogata S, Uemura T, Ohtsuki S, Minegishi G, Akita H, Chiba K, Oshimura M, Kazuki Y.

Drug Metab Dispos. 2018 Nov;46(11):1756-1766. doi: 10.1124/dmd.118.081216. Epub 2018 May 18.


Markers of brain illness may be hidden in your olfactory ability: a Japanese perspective.

Masaoka Y, Pantelis C, Phillips A, Kawamura M, Mimura M, Minegishi G, Homma I.

Neurosci Lett. 2013 Aug 9;549:182-5. doi: 10.1016/j.neulet.2013.05.077. Epub 2013 Jun 13.


Donepezil abolishes anticholinergic activity in a patient with amnesia.

Konishi K, Hori K, Tomioka H, Minegishi G, Tani M, Tanaka H, Akita R, Yokoyama S, Oshio T, Hachisu M.

Pharmacology. 2013;91(1-2):86-91. doi: 10.1159/000345344. Epub 2012 Dec 14.

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