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Analysis of macular curvature in normal eyes using swept-source optical coherence tomography.

Minami S, Ito Y, Ueno S, Kataoka K, Takeuchi J, Ito H, Nakano Y, Kitagawa M, Leahy C, Straub J, Terasaki H.

Jpn J Ophthalmol. 2020 Feb 10. doi: 10.1007/s10384-020-00721-8. [Epub ahead of print]


Spinal Alignments of Residual Lumbar Curve Affect Disc Degeneration after Spinal Fusion in Patients with Adolescent Idiopathic Scoliosis: Follow-up after 5 or More Years.

Akazawa T, Umehara T, Iinuma M, Asano K, Kuroya S, Torii Y, Murakami K, Kotani T, Sakuma T, Minami S, Orita S, Inage K, Shiga Y, Nakamura J, Inoue G, Miyagi M, Saito W, Eguchi Y, Fujimoto K, Takahashi H, Ohtori S, Niki H.

Spine Surg Relat Res. 2019 Aug 16;4(1):50-56. doi: 10.22603/ssrr.2019-0048. eCollection 2020.


Autophagy protects kidney from phosphate-induced mitochondrial injury.

Fujimura R, Yamamoto T, Takabatake Y, Takahashi A, Namba-Hamano T, Minami S, Sakai S, Matsuda J, Hesaka A, Yonishi H, Nakamura J, Matsui I, Matsusaka T, Niimura F, Yanagita M, Isaka Y.

Biochem Biophys Res Commun. 2020 Feb 3. pii: S0006-291X(20)30220-5. doi: 10.1016/j.bbrc.2020.01.137. [Epub ahead of print]


Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells.

Matsuda J, Takahashi A, Takabatake Y, Sakai S, Minami S, Yamamoto T, Fujimura R, Namba-Hamano T, Yonishi H, Nakamura J, Kimura T, Kaimori JY, Matsui I, Takahashi M, Nakao M, Izumi Y, Bamba T, Matsusaka T, Niimura F, Yanagita M, Yoshimori T, Isaka Y.

Autophagy. 2020 Jan 16:1-16. doi: 10.1080/15548627.2020.1712107. [Epub ahead of print]


A multicenter phase II trial of paclitaxel, carboplatin, and cetuximab followed by chemoradiotherapy in patients with unresectable locally advanced squamous cell carcinoma of the head and neck.

Enokida T, Ogawa T, Homma A, Okami K, Minami S, Nakanome A, Shimizu Y, Maki D, Ueda Y, Fujisawa T, Motegi A, Ohkoshi A, Taguchi J, Ebisumoto K, Nomura S, Okano S, Tahara M.

Cancer Med. 2020 Jan 13. doi: 10.1002/cam4.2852. [Epub ahead of print]


Low Body Mass Index Is an Independent Prognostic Factor in Patients With Non-Small Cell Lung Cancer Treated With Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor.

Minami S, Ihara S, Nishimatsu K, Komuta K.

World J Oncol. 2019 Dec;10(6):187-198. doi: 10.14740/wjon1244. Epub 2019 Dec 16.


BAG6 contributes to glucose uptake by supporting the cell surface translocation of the glucose transporter GLUT4.

Minami S, Yokota N, Kawahara H.

Biol Open. 2020 Jan 24;9(1). pii: bio047324. doi: 10.1242/bio.047324.


Clinical application of intraoperative O-arm navigation in reverse shoulder arthroplasty.

Sasaki Y, Ochiai N, Kotani T, Kenmoku T, Hashimoto E, Kishida S, Sakuma T, Muramatsu Y, Ueno K, Nakayama K, Iijima Y, Minami S, Ohtori S.

J Orthop Sci. 2019 Dec 18. pii: S0949-2658(19)30341-0. doi: 10.1016/j.jos.2019.11.003. [Epub ahead of print]


A prospective compound screening contest identified broader inhibitors for Sirtuin 1.

Chiba S, Ohue M, Gryniukova A, Borysko P, Zozulya S, Yasuo N, Yoshino R, Ikeda K, Shin WH, Kihara D, Iwadate M, Umeyama H, Ichikawa T, Teramoto R, Hsin KY, Gupta V, Kitano H, Sakamoto M, Higuchi A, Miura N, Yura K, Mochizuki M, Ramakrishnan C, Thangakani AM, Velmurugan D, Gromiha MM, Nakane I, Uchida N, Hakariya H, Tan M, Nakamura HK, Suzuki SD, Ito T, Kawatani M, Kudoh K, Takashina S, Yamamoto KZ, Moriwaki Y, Oda K, Kobayashi D, Okuno T, Minami S, Chikenji G, Prathipati P, Nagao C, Mohsen A, Ito M, Mizuguchi K, Honma T, Ishida T, Hirokawa T, Akiyama Y, Sekijima M.

Sci Rep. 2019 Dec 20;9(1):19585. doi: 10.1038/s41598-019-55069-y.


Effect of axial length and age on the visual outcome of patients with idiopathic epiretinal membrane after pars plana vitrectomy.

Minami S, Shinoda H, Shigeno Y, Nagai N, Kurihara T, Watanabe K, Sonobe H, Takagi H, Tsubota K, Ozawa Y.

Sci Rep. 2019 Dec 13;9(1):19056. doi: 10.1038/s41598-019-55544-6.


Spatial-sweep steady-state pattern electroretinography can detect subtle differences in visual function among healthy adults.

Minami S, Nagai N, Suzuki M, Kurihara T, Sonobe H, Watanabe K, Shinoda H, Takagi H, Tsubota K, Ozawa Y.

Sci Rep. 2019 Dec 2;9(1):18119. doi: 10.1038/s41598-019-54606-z.


Electrically evoked ABR during cochlear implantation and postoperative development of speech and hearing abilities in infants with common cavity deformity as a type of inner ear malformation.

Kaga K, Minami S, Enomoto C.

Acta Otolaryngol. 2020 Jan;140(1):14-21. doi: 10.1080/00016489.2019.1692147. Epub 2019 Nov 25.


Growth hormone activates X-box binding protein 1 in a sexually dimorphic manner through the extracellular signal-regulated protein kinase and CCAAT/enhancer-binding protein β pathway in rat liver.

Nakata T, Hirano Y, Katsumata H, Tokita R, Yagi T, Toyoshima Y, Minami S.

Endocr J. 2019 Nov 19. doi: 10.1507/endocrj.EJ19-0240. [Epub ahead of print]


Predicting recurrences of macular edema due to branch retinal vein occlusion during anti-vascular endothelial growth factor therapy.

Suzuki M, Nagai N, Minami S, Kurihara T, Kamoshita M, Sonobe H, Watanabe K, Shinoda H, Tsubota K, Ozawa Y.

Graefes Arch Clin Exp Ophthalmol. 2020 Jan;258(1):49-56. doi: 10.1007/s00417-019-04495-9. Epub 2019 Nov 15.


Dietary Habits Had No Relationship with Adolescent Idiopathic Scoliosis: Analysis Utilizing Quantitative Data about Dietary Intakes.

Asakura K, Michikawa T, Takaso M, Minami S, Soshi S, Tsuji T, Okada E, Abe K, Takahashi M, Matsumoto M, Nishiwaki Y, Watanabe K.

Nutrients. 2019 Oct 1;11(10). pii: E2327. doi: 10.3390/nu11102327.


Involvement of sarco/endoplasmic reticulum calcium ATPase-mediated calcium flux in the protective effect of oleic acid against lipotoxicity in hepatocytes.

Ogino N, Miyagawa K, Kusanaga M, Hayashi T, Minami S, Oe S, Honma Y, Harada M.

Exp Cell Res. 2019 Dec 1;385(1):111651. doi: 10.1016/j.yexcr.2019.111651. Epub 2019 Sep 27.


Ultra-Widefield Retinal Imaging for Analyzing the Association Between Types of Pathological Myopia and Posterior Staphyloma.

Mimura R, Mori K, Torii H, Nagai N, Suzuki M, Minami S, Ozawa Y, Kurihara T, Tsubota K.

J Clin Med. 2019 Sep 20;8(10). pii: E1505. doi: 10.3390/jcm8101505.


MRI evaluation of dural sac enlargement by interspinous process spacers in patients with lumbar spinal stenosis: Does it play a role in the long term?

Akazawa T, Kotani T, Sakuma T, Torii Y, Iinuma M, Asano K, Ueno J, Yoshida A, Murakami K, Minami S, Orita S, Inage K, Shiga Y, Nakamura J, Inoue G, Miyagi M, Saito W, Eguchi Y, Fujimoto K, Takahashi H, Ohtori S, Niki H.

J Orthop Sci. 2019 Nov;24(6):979-984. doi: 10.1016/j.jos.2019.08.018. Epub 2019 Sep 16.


Japanese adaptation of the Bad Sobernheim Stress Questionnaire-Brace for patients with adolescent idiopathic scoliosis.

Asada T, Kotani T, Nakayama K, Sasaki T, Fujii K, Sunami T, Sakuma T, Iijima Y, Akazawa T, Minami S, Ohtori S, Koda M, Yamazaki M.

J Orthop Sci. 2019 Nov;24(6):1010-1014. doi: 10.1016/j.jos.2019.08.003. Epub 2019 Sep 10.


Importance of a Liver Biopsy in the Management of Wilson Disease.

Oe S, Honma Y, Yabuki K, Morino K, Kumamoto K, Hayashi T, Kusanaga M, Ogino N, Minami S, Shibata M, Abe S, Harada M.

Intern Med. 2020 Jan 1;59(1):77-81. doi: 10.2169/internalmedicine.3440-19. Epub 2019 Sep 11.


Drug interactions between warfarin and lenvatinib in a patient with the CYP2C9*1/*3 and VKORC1-1639G/A genotype.

Yagishita H, Minami S, Akamine Y, Kato S, Iijima K, Miura M.

J Clin Pharm Ther. 2019 Dec;44(6):977-980. doi: 10.1111/jcpt.13030. Epub 2019 Aug 30.


Assessment of Myocardial Ischemic Memory Using Three-Dimensional Speckle-Tracking Echocardiography: A Novel Integrated Analysis of Early Systolic Lengthening and Postsystolic Shortening.

Kozuma A, Asanuma T, Masuda K, Adachi H, Minami S, Nakatani S.

J Am Soc Echocardiogr. 2019 Nov;32(11):1477-1486. doi: 10.1016/j.echo.2019.06.013. Epub 2019 Aug 26.


Thoracic Deformity Correction and Changes of Vital Capacity, Forced Expiratory Volume in 1 Second, and Expiratory Flow in Adolescent Idiopathic Scoliosis Five Years or More after Posterior Spinal Fusion with Thoracoplasty.

Akazawa T, Iinuma M, Kuroya S, Torii Y, Umehara T, Murakami K, Kotani T, Sakuma T, Minami S, Orita S, Inage K, Fujimoto K, Shiga Y, Nakamura J, Inoue G, Miyagi M, Saito W, Ohtori S, Niki H.

Spine Surg Relat Res. 2018 Dec 1;3(3):222-228. doi: 10.22603/ssrr.2018-0075. eCollection 2019.


Rapid Progression of Scoliosis Requiring Re-Instrumentation after Implant Removal Due to Infection Following Posterior Spinal Fusion and Instrumentation.

Nakayama K, Kotani T, Sakuma T, Kishida S, Muramatsu Y, Sasaki Y, Ueno K, Iijima Y, Akazawa T, Yamazaki M, Minami S.

Spine Surg Relat Res. 2018 Oct 19;3(1):102-105. doi: 10.22603/ssrr.2018-0039. eCollection 2019 Jan 25. No abstract available.


The impact of antithrombotic therapy in patients undergoing emergency laparoscopic cholecystectomy for acute cholecystitis - A single center experience.

Imamura H, Minami S, Isagawa Y, Morita M, Hirabaru M, Kawahara D, Tokai H, Noda K, Inoue K, Haraguchi M, Eguchi S.

Asian J Endosc Surg. 2019 Aug 20. doi: 10.1111/ases.12751. [Epub ahead of print]


Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese.

Kou I, Otomo N, Takeda K, Momozawa Y, Lu HF, Kubo M, Kamatani Y, Ogura Y, Takahashi Y, Nakajima M, Minami S, Uno K, Kawakami N, Ito M, Yonezawa I, Watanabe K, Kaito T, Yanagida H, Taneichi H, Harimaya K, Taniguchi Y, Shigematsu H, Iida T, Demura S, Sugawara R, Fujita N, Yagi M, Okada E, Hosogane N, Kono K, Nakamura M, Chiba K, Kotani T, Sakuma T, Akazawa T, Suzuki T, Nishida K, Kakutani K, Tsuji T, Sudo H, Iwata A, Sato T, Inami S, Matsumoto M, Terao C, Watanabe K, Ikegawa S.

Nat Commun. 2019 Aug 15;10(1):3685. doi: 10.1038/s41467-019-11596-w.


Dynamic changes in choroidal conditions during anti-vascular endothelial growth factor therapy in polypoidal choroidal vasculopathy.

Nagai N, Suzuki M, Minami S, Kurihara T, Kamoshita M, Sonobe H, Watanabe K, Uchida A, Shinoda H, Tsubota K, Ozawa Y.

Sci Rep. 2019 Aug 6;9(1):11389. doi: 10.1038/s41598-019-47738-9.


Self-study of the non-extension sign in an e-learning program improves diagnostic accuracy of invasion depth of early gastric cancer.

Kato M, Uedo N, Nagahama T, Yao K, Doyama H, Tsuji S, Gotoda T, Kawamura T, Ebi M, Yamamoto K, Akasaka T, Takatori H, Handa O, Akamatsu T, Nishikawa J, Hikichi T, Yamashina T, Imoto A, Kitamura Y, Mikami T, Koike T, Ohara S, Kitamura S, Yamaguchi T, Kinjo T, Inoue T, Suzuki S, Kaneko A, Hirasawa K, Tanaka K, Kotachi T, Miwa K, Toya Y, Kayaba S, Ikehata A, Minami S, Mizukami K, Oya H, Ara N, Fukumoto Y, Komura T, Yoshio T, Morizono R, Yamazaki K, Shimodate Y, Yamanouchi K, Kawata N, Kumagai M, Sato Y, Umeki K, Kawai D, Tanuma T, Kishino M, Konishi J, Sumiyoshi T, Oka S, Kono M, Sakamoto T, Horikawa Y, Ohyauchi M, Hashiguchi K, Waseda Y, Kasai T, Aoyagi H, Oyamada H, Shoji M, Kiyotoki S, Asonuma S, Orikasa S, Akaishi C, Nagami Y, Nakata S, Iida F, Nomura T, Tominaga K, Oka K, Morita Y, Suzuki H, Ozeki K, Kuribayashi S, Akazawa Y, Sasaki S, Mikami T, Miki G, Sano T, Satoh H, Nakamura M, Iwai W, Tawa H, Wada M, Yoshimura D, Hisanaga Y, Shimokawa T, Ishikawa H.

Endosc Int Open. 2019 Jul;7(7):E871-E882. doi: 10.1055/a-0902-4467. Epub 2019 Jul 3.


The lateral intercalated cell mass of the amygdala is activated during social buffering of conditioned fear responses in male rats.

Minami S, Kiyokawa Y, Takeuchi Y.

Behav Brain Res. 2019 Oct 17;372:112065. doi: 10.1016/j.bbr.2019.112065. Epub 2019 Jun 28.


Patients majoring in a healthcare field after scoliosis surgery: Comparison with the national census in Japan.

Kotani T, Sakuma T, Nakayama K, Iijima Y, Watanabe K, Isogai N, Akazawa T, Sato K, Asada T, Kishida S, Muramatsu Y, Sasaki Y, Ueno K, Katogi T, Minami S, Inage K, Shiga Y, Ohtori S.

J Orthop Sci. 2019 Jun 25. pii: S0949-2658(19)30183-6. doi: 10.1016/j.jos.2019.06.002. [Epub ahead of print]


Synthesis of a one-handed helical polythiophene: a new approach using an axially chiral bithiophene with a fixed syn-conformation.

Ikai T, Takayama K, Wada Y, Minami S, Apiboon C, Shinohara KI.

Chem Sci. 2019 Apr 3;10(18):4890-4895. doi: 10.1039/c9sc00342h. eCollection 2019 May 14.


The structure and properties of natural sheep casing and artificial films prepared from natural collagen with various crosslinking treatments.

Chen X, Zhou L, Xu H, Yamamoto M, Shinoda M, Tada I, Minami S, Urayama K, Yamane H.

Int J Biol Macromol. 2019 Aug 15;135:959-968. doi: 10.1016/j.ijbiomac.2019.05.182. Epub 2019 May 25.


Low-protein diet enhances adiponectin secretion in rats.

Yagi T, Toyoshima Y, Tokita R, Taguchi Y, Okamoto Y, Takahashi SI, Kato H, Minami S.

Biosci Biotechnol Biochem. 2019 Sep;83(9):1774-1781. doi: 10.1080/09168451.2019.1621153. Epub 2019 May 27.


Hooks at the Upper Instrumented Vertebra Can Adjust Postoperative Shoulder Balance in Patients with Adolescent Idiopathic Scoliosis: 5 Years or More of Follow-up.

Kuroya S, Akazawa T, Kotani T, Sakuma T, Minami S, Torii Y, Umehara T, Iinuma M, Murakami K, Orita S, Inage K, Eguchi Y, Fujimoto K, Shiga Y, Nakamura J, Inoue G, Miyagi M, Saito W, Ohtori S, Niki H.

Asian Spine J. 2019 May 14;13(5):793-800. doi: 10.31616/asj.2018.0206. Print 2019 Oct.


Gustave Roussy Immune Score and Royal Marsden Hospital Prognostic Score Are Biomarkers of Immune-Checkpoint Inhibitor for Non-Small Cell Lung Cancer.

Minami S, Ihara S, Ikuta S, Komuta K.

World J Oncol. 2019 Apr;10(2):90-100. doi: 10.14740/wjon1193. Epub 2019 Apr 20.


Zinc Attenuates the Cytotoxicity of Some Stimuli by Reducing Endoplasmic Reticulum Stress in Hepatocytes.

Kusanaga M, Oe S, Ogino N, Minami S, Miyagawa K, Honma Y, Harada M.

Int J Mol Sci. 2019 May 3;20(9). pii: E2192. doi: 10.3390/ijms20092192.


Proximal Tubule Autophagy Differs in Type 1 and 2 Diabetes.

Sakai S, Yamamoto T, Takabatake Y, Takahashi A, Namba-Hamano T, Minami S, Fujimura R, Yonishi H, Matsuda J, Hesaka A, Matsui I, Matsusaka T, Niimura F, Yanagita M, Isaka Y.

J Am Soc Nephrol. 2019 Jun;30(6):929-945. doi: 10.1681/ASN.2018100983. Epub 2019 Apr 30.


Bi-allelic loss of function variants of TBX6 causes a spectrum of malformation of spine and rib including congenital scoliosis and spondylocostal dysostosis.

Otomo N, Takeda K, Kawai S, Kou I, Guo L, Osawa M, Alev C, Kawakami N, Miyake N, Matsumoto N, Yasuhiko Y, Kotani T, Suzuki T, Uno K, Sudo H, Inami S, Taneichi H, Shigematsu H, Watanabe K, Yonezawa I, Sugawara R, Taniguchi Y, Minami S, Kaneko K, Nakamura M, Matsumoto M, Toguchida J, Watanabe K, Ikegawa S.

J Med Genet. 2019 Sep;56(9):622-628. doi: 10.1136/jmedgenet-2018-105920. Epub 2019 Apr 22.


Effect of direct-acting antivirals on platelet-associated immunoglobulin G and thrombocytopenia in hepatitis C virus-related chronic liver disease.

Honma Y, Shibata M, Hayashi T, Kusanaga M, Ogino N, Minami S, Kumei S, Oe S, Miyagawa K, Senju M, Matsuoka H, Watanabe T, Hiura M, Abe S, Harada M.

Liver Int. 2019 Sep;39(9):1641-1651. doi: 10.1111/liv.14120. Epub 2019 May 24.


MYRF haploinsufficiency causes 46,XY and 46,XX disorders of sex development: bioinformatics consideration.

Hamanaka K, Takata A, Uchiyama Y, Miyatake S, Miyake N, Mitsuhashi S, Iwama K, Fujita A, Imagawa E, Alkanaq AN, Koshimizu E, Azuma Y, Nakashima M, Mizuguchi T, Saitsu H, Wada Y, Minami S, Katoh-Fukui Y, Masunaga Y, Fukami M, Hasegawa T, Ogata T, Matsumoto N.

Hum Mol Genet. 2019 Jul 15;28(14):2319-2329. doi: 10.1093/hmg/ddz066.


A clinical and genetic study of 16 Japanese families with Waardenburg syndrome.

Minami SB, Nara K, Mutai H, Morimoto N, Sakamoto H, Takiguchi T, Kaga K, Matsunaga T.

Gene. 2019 Jul 1;704:86-90. doi: 10.1016/j.gene.2019.04.023. Epub 2019 Apr 10.


Acute appendicitis associated with the presence of schistosome eggs in a sailor: a case report.

Imamura H, Haraguchi M, Isagawa Y, Morita M, Hirabaru M, Kawahara D, Tokai H, Noda K, Minami S, Inoue K, Irie J, Eguchi S.

Surg Case Rep. 2019 Apr 8;5(1):55. doi: 10.1186/s40792-019-0615-8.


Integrated datasets of normalized brain with functional localization using intra-operative electrical stimulation.

Tamura M, Sato I, Maruyama T, Ohshima K, Mangin JF, Nitta M, Saito T, Yamada H, Minami S, Masamune K, Kawamata T, Iseki H, Muragaki Y.

Int J Comput Assist Radiol Surg. 2019 Dec;14(12):2109-2122. doi: 10.1007/s11548-019-01957-7. Epub 2019 Apr 6.


Detection of a novel tick-borne flavivirus and its serological surveillance.

Shimoda H, Hayasaka D, Yoshii K, Yokoyama M, Suzuki K, Kodera Y, Takeda T, Mizuno J, Noguchi K, Yonemitsu K, Minami S, Kuwata R, Takano A, Maeda K.

Ticks Tick Borne Dis. 2019 Jun;10(4):742-748. doi: 10.1016/j.ttbdis.2019.03.006. Epub 2019 Mar 16.


Genome-wide Identification of Tebufenozide Resistant Genes in the smaller tea tortrix, Adoxophyes honmai (Lepidoptera: Tortricidae).

Uchibori-Asano M, Jouraku A, Uchiyama T, Yokoi K, Akiduki G, Suetsugu Y, Kobayashi T, Ozawa A, Minami S, Ishizuka C, Nakagawa Y, Daimon T, Shinoda T.

Sci Rep. 2019 Mar 12;9(1):4203. doi: 10.1038/s41598-019-40863-5.


Short term outcomes of helical tomotherapy during concurrent chemoradiotherapy for advanced cervical cancer.

Mabuchi Y, Takiguchi Y, Yahata T, Mizoguchi M, Sasaki N, Ota N, Minami S, Ino K.

Mol Clin Oncol. 2019 Mar;10(3):382-386. doi: 10.3892/mco.2019.1806. Epub 2019 Jan 23.


Association of Pain History and Current Pain With Sagittal Spinal Alignment and Muscle Stiffness and Muscle Mass of the Back Muscles in Middle-aged and Elderly Women.

Masaki M, Ikezoe T, Yanase K, Ji X, Umehara J, Aoyama J, Minami S, Fukumoto Y, Watanabe Y, Kimura M, Ichihashi N.

Clin Spine Surg. 2019 Aug;32(7):E346-E352. doi: 10.1097/BSD.0000000000000793.


Post-assembly Fabrication of a Functional Multicomponent Supramolecular Hydrogel Based on a Self-Sorting Double Network.

Tanaka W, Shigemitsu H, Fujisaku T, Kubota R, Minami S, Urayama K, Hamachi I.

J Am Chem Soc. 2019 Mar 27;141(12):4997-5004. doi: 10.1021/jacs.9b00715. Epub 2019 Mar 14.


Gustave Roussy Immune Score Is a Prognostic Factor for Chemotherapy-Naive Pulmonary Adenocarcinoma With Wild-Type Epidermal Growth Factor Receptor.

Minami S, Ihara S, Komuta K.

World J Oncol. 2019 Feb;10(1):55-61. doi: 10.14740/wjon1184. Epub 2019 Feb 26.


Pretreatment Lung Immune Prognostic Index Is a Prognostic Marker of Chemotherapy and Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor.

Minami S, Ihara S, Komuta K.

World J Oncol. 2019 Feb;10(1):35-45. doi: 10.14740/wjon1179. Epub 2019 Feb 26.

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