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Items: 19

1.

6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers.

Yang H, Shu Z, Jiang Y, Mao W, Pang L, Redwood A, Jeter-Jones SL, Jennings NB, Ornelas A, Zhou J, Rodriguez-Aguayo C, Bartholomeusz G, Iles LR, Zacharias NM, Millward SW, Lopez-Berestein G, Le XF, Ahmed AA, Piwnica-Worms H, Sood AK, Bast RC, Lu Z.

Clin Cancer Res. 2019 Sep 15;25(18):5702-5716. doi: 10.1158/1078-0432.CCR-18-3448. Epub 2019 Aug 7.

PMID:
31391192
2.

Assessing Metabolic Intervention with a Glutaminase Inhibitor in Real-time by Hyperpolarized Magnetic Resonance in Acute Myeloid Leukemia.

Zacharias NM, Baran N, Shanmugavelandy SS, Lee J, Velez Lujan J, Dutta P, Millward SW, Cai T, Wood CG, Piwnica-Worms D, Konopleva M, Bhattacharya PK.

Mol Cancer Ther. 2019 Aug 6. pii: molcanther.0985.2018. doi: 10.1158/1535-7163.MCT-18-0985. [Epub ahead of print]

PMID:
31387889
3.

DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1.

Sutton MN, Huang GY, Liang X, Sharma R, Reger AS, Mao W, Pang L, Rask PJ, Lee K, Gray JP, Hurwitz AM, Palzkill T, Millward SW, Kim C, Lu Z, Bast RC Jr.

Cancers (Basel). 2019 Apr 18;11(4). pii: E557. doi: 10.3390/cancers11040557.

4.

Real-Time Interrogation of Aspirin Reactivity, Biochemistry, and Biodistribution by Hyperpolarized Magnetic Resonance Spectroscopy.

Zacharias NM, Ornelas A, Lee J, Hu J, Davis JS, Uddin N, Pudakalakatti S, Menter DG, Karam JA, Wood CG, Hawk ET, Kopetz S, Vilar E, Bhattacharya PK, Millward SW.

Angew Chem Int Ed Engl. 2019 Mar 22;58(13):4179-4183. doi: 10.1002/anie.201812759. Epub 2019 Feb 20.

5.

Caspase-3 Substrates for Noninvasive Pharmacodynamic Imaging of Apoptosis by PET/CT.

Engel BJ, Gammon ST, Chaudhari R, Lu Z, Pisaneschi F, Yang H, Ornelas A, Yan V, Kelderhouse L, Najjar AM, Tong WP, Zhang S, Piwnica-Worms D, Bast RC Jr, Millward SW.

Bioconjug Chem. 2018 Sep 19;29(9):3180-3195. doi: 10.1021/acs.bioconjchem.8b00514. Epub 2018 Aug 31.

6.

Bioactive lipid metabolism in platelet "first responder" and cancer biology.

Kanikarla-Marie P, Kopetz S, Hawk ET, Millward SW, Sood AK, Gresele P, Overman M, Honn K, Menter DG.

Cancer Metastasis Rev. 2018 Sep;37(2-3):439-454. doi: 10.1007/s10555-018-9755-8. Review.

PMID:
30112590
7.

Automated, Resin-Based Method to Enhance the Specific Activity of Fluorine-18 Clicked PET Radiotracers.

Pisaneschi F, Kelderhouse LE, Hardy A, Engel BJ, Mukhopadhyay U, Gonzalez-Lepera C, Gray JP, Ornelas A, Takahashi TT, Roberts RW, Fiacco SV, Piwnica-Worms D, Millward SW.

Bioconjug Chem. 2017 Feb 15;28(2):583-589. doi: 10.1021/acs.bioconjchem.6b00678. Epub 2017 Feb 2.

8.

Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models.

Ornelas A, McCullough CR, Lu Z, Zacharias NM, Kelderhouse LE, Gray J, Yang H, Engel BJ, Wang Y, Mao W, Sutton MN, Bhattacharya PK, Bast RC Jr, Millward SW.

BMC Cancer. 2016 Oct 26;16(1):824.

9.

Directed Evolution of Scanning Unnatural-Protease-Resistant (SUPR) Peptides for in Vivo Applications.

Fiacco SV, Kelderhouse LE, Hardy A, Peleg Y, Hu B, Ornelas A, Yang P, Gammon ST, Howell SM, Wang P, Takahashi TT, Millward SW, Roberts RW.

Chembiochem. 2016 Sep 2;17(17):1643-51. doi: 10.1002/cbic.201600253. Epub 2016 Jul 28.

10.

A protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH domain of Akt1.

Deyle KM, Farrow B, Qiao Hee Y, Work J, Wong M, Lai B, Umeda A, Millward SW, Nag A, Das S, Heath JR.

Nat Chem. 2015 May;7(5):455-62. doi: 10.1038/nchem.2223. Epub 2015 Apr 13.

11.

Serum stable natural peptides designed by mRNA display.

Howell SM, Fiacco SV, Takahashi TT, Jalali-Yazdi F, Millward SW, Hu B, Wang P, Roberts RW.

Sci Rep. 2014 Sep 19;4:6008. doi: 10.1038/srep06008.

12.

A chemical epitope-targeting strategy for protein capture agents: the serine 474 epitope of the kinase Akt2.

Nag A, Das S, Yu MB, Deyle KM, Millward SW, Heath JR.

Angew Chem Int Ed Engl. 2013 Dec 23;52(52):13975-9. doi: 10.1002/anie.201305882. Epub 2013 Nov 19. No abstract available.

13.

In situ click chemistry: from small molecule discovery to synthetic antibodies.

Millward SW, Agnew HD, Lai B, Lee SS, Lim J, Nag A, Pitram S, Rohde R, Heath JR.

Integr Biol (Camb). 2013 Jan;5(1):87-95. doi: 10.1039/c2ib20110k. Review.

14.

Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1.

Millward SW, Henning RK, Kwong GA, Pitram S, Agnew HD, Deyle KM, Nag A, Hein J, Lee SS, Lim J, Pfeilsticker JA, Sharpless KB, Heath JR.

J Am Chem Soc. 2011 Nov 16;133(45):18280-8. doi: 10.1021/ja2064389. Epub 2011 Oct 24.

15.

Iterative in situ click chemistry creates antibody-like protein-capture agents.

Agnew HD, Rohde RD, Millward SW, Nag A, Yeo WS, Hein JE, Pitram SM, Tariq AA, Burns VM, Krom RJ, Fokin VV, Sharpless KB, Heath JR.

Angew Chem Int Ed Engl. 2009;48(27):4944-8. doi: 10.1002/anie.200900488.

16.

Design of cyclic peptides that bind protein surfaces with antibody-like affinity.

Millward SW, Fiacco S, Austin RJ, Roberts RW.

ACS Chem Biol. 2007 Sep 21;2(9):625-34.

17.

A general route for post-translational cyclization of mRNA display libraries.

Millward SW, Takahashi TT, Roberts RW.

J Am Chem Soc. 2005 Oct 19;127(41):14142-3.

PMID:
16218582
18.

Encodamers: unnatural peptide oligomers encoded in RNA.

Frankel A, Millward SW, Roberts RW.

Chem Biol. 2003 Nov;10(11):1043-50.

PMID:
14652071
19.

Normal sexual development of rats exposed to butyl benzyl phthalate from conception to weaning.

Ashby J, Tinwell H, Lefevre PA, Odum J, Paton D, Millward SW, Tittensor S, Brooks AN.

Regul Toxicol Pharmacol. 1997 Aug;26(1 Pt 1):102-18.

PMID:
9339487

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