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Items: 1 to 50 of 79

1.

Coupling Krebs cycle metabolites to signalling in immunity and cancer.

Ryan DG, Murphy MP, Frezza C, Prag HA, Chouchani ET, O'Neill LA, Mills EL.

Nat Metab. 2019 Jan;1:16-33. doi: 10.1038/s42255-018-0014-7.

2.

Accumulation of succinate controls activation of adipose tissue thermogenesis.

Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, Clish CB, Chouchani ET.

Nature. 2018 Aug;560(7716):102-106. doi: 10.1038/s41586-018-0353-2. Epub 2018 Jul 18.

PMID:
30022159
3.

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA.

Nature. 2018 Apr 5;556(7699):113-117. doi: 10.1038/nature25986. Epub 2018 Mar 28.

4.

Evaluating the Impact of the Addition of Cladribine to Standard Acute Myeloid Leukemia Induction Therapy.

Seligson ND, Hobbs ALV, Leonard JM, Mills EL, Evans AG, Goorha S.

Ann Pharmacother. 2018 May;52(5):439-445. doi: 10.1177/1060028017749214. Epub 2017 Dec 14.

PMID:
29241342
5.

Mitochondria are the powerhouses of immunity.

Mills EL, Kelly B, O'Neill LAJ.

Nat Immunol. 2017 Apr 18;18(5):488-498. doi: 10.1038/ni.3704. Review.

PMID:
28418387
6.

Inflammasome Priming in Sterile Inflammatory Disease.

Patel MN, Carroll RG, Galván-Peña S, Mills EL, Olden R, Triantafilou M, Wolf AI, Bryant CE, Triantafilou K, Masters SL.

Trends Mol Med. 2017 Feb;23(2):165-180. doi: 10.1016/j.molmed.2016.12.007. Epub 2017 Jan 18. Review.

PMID:
28109721
7.

Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice.

Dempsey C, Rubio Araiz A, Bryson KJ, Finucane O, Larkin C, Mills EL, Robertson AAB, Cooper MA, O'Neill LAJ, Lynch MA.

Brain Behav Immun. 2017 Mar;61:306-316. doi: 10.1016/j.bbi.2016.12.014. Epub 2016 Dec 18.

PMID:
28003153
8.

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.

Mills EL, Kelly B, Logan A, Costa ASH, Varma M, Bryant CE, Tourlomousis P, Däbritz JHM, Gottlieb E, Latorre I, Corr SC, McManus G, Ryan D, Jacobs HT, Szibor M, Xavier RJ, Braun T, Frezza C, Murphy MP, O'Neill LA.

Cell. 2016 Oct 6;167(2):457-470.e13. doi: 10.1016/j.cell.2016.08.064. Epub 2016 Sep 22.

9.

Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal.

Mills EL, O'Neill LA.

Eur J Immunol. 2016 Jan;46(1):13-21. doi: 10.1002/eji.201445427. Review.

10.

Increased benthic algal primary production in response to the invasive zebra mussel (Dreissena polymorpha) in a productive ecosystem, Oneida Lake, New York.

Cecala RK, Mayer CM, Schulz KL, Mills EL.

J Integr Plant Biol. 2008 Nov;50(11):1452-66. doi: 10.1111/j.1744-7909.2008.00755.x.

PMID:
19017132
11.
12.

A third-generation, posterior-stabilized knee prosthesis: early results after follow-up of 2 to 6 years.

Fuchs R, Mills EL, Clarke HD, Scuderi GR, Scott WN, Insall JN.

J Arthroplasty. 2006 Sep;21(6):821-5.

PMID:
16950033
13.

The influence of femoral component design in the elimination of patellar clunk in posterior-stabilized total knee arthroplasty.

Clarke HD, Fuchs R, Scuderi GR, Mills EL, Scott WN, Insall JN.

J Arthroplasty. 2006 Feb;21(2):167-71.

PMID:
16520202
14.

Risk factors for hospitalization and infection in Canadian Inuit infants over the first year of life--a pilot study.

Jenkins AL, Gyorkos TW, Joseph L, Culman KN, Ward BJ, Pekeles GS, Mills EL.

Int J Circumpolar Health. 2004 Mar;63(1):61-70.

PMID:
15139241
15.

An overview of factors influencing the health of Canadian Inuit infants.

Jenkins AL, Gyorkos TW, Culman KN, Ward BJ, Pekeles GS, Mills EL.

Int J Circumpolar Health. 2003 Mar;62(1):17-39. Review.

PMID:
12725339
16.

Safety and immunogenicity of a trivalent, inactivated, mammalian cell culture-derived influenza vaccine in healthy adults, seniors, and children.

Halperin SA, Smith B, Mabrouk T, Germain M, Trépanier P, Hassell T, Treanor J, Gauthier R, Mills EL.

Vaccine. 2002 Jan 15;20(7-8):1240-7.

PMID:
11803087
17.

Lower respiratory tract infections in Inuit infants on Baffin Island.

Banerji A, Bell A, Mills EL, McDonald J, Subbarao K, Stark G, Eynon N, Loo VG.

CMAJ. 2001 Jun 26;164(13):1847-50.

18.

Toxic and nutrient element concentrations in soft tissues of zebra and quagga mussels from Lakes Erie and Ontario.

Rutzke MA, Gutenmann WH, Lisk DJ, Mills EL.

Chemosphere. 2000 Jun;40(12):1353-6.

PMID:
10789974
19.

Mutational analysis of the promoter region of the porA gene of Neisseria meningitidis.

Sawaya R, Arhin FF, Moreau F, Coulton JW, Mills EL.

Gene. 1999 Jun 11;233(1-2):49-57.

PMID:
10375620
20.

Acute-phase neurologic complications of Haemophilus influenzae type b meningitis: association with developmental problems at school age.

Taylor HG, Schatschneider C, Watters GV, Mills EL, Gold R, MacDonald N, Michaels RH.

J Child Neurol. 1998 Mar;13(3):113-9.

PMID:
9535236
21.

Sequencing of porA from clinical isolates of Neisseria meningitidis defines a subtyping scheme and its genetic regulation.

Arhin FF, Moreau F, Coulton JW, Mills EL.

Can J Microbiol. 1998 Jan;44(1):56-63.

PMID:
9522450
22.

Parental willingness to enter a child in a controlled vaccine trial.

Langley JM, Halperin SA, Mills EL, Eastwood B.

Clin Invest Med. 1998 Feb;21(1):12-6.

PMID:
9512880
23.
24.

Outer membrane proteins and serosubtyping with outer membrane vesicles from clinical isolates of Neisseria meningitidis.

Arhin FF, Moreau F, Coulton JW, Mills EL.

Curr Microbiol. 1997 Jan;34(1):18-22.

PMID:
8939796
25.

Biochemical mediators of meningeal inflammatory response to group B streptococcus in the newborn piglet model.

Ling EW, Noya FJ, Ricard G, Beharry K, Mills EL, Aranda JV.

Pediatr Res. 1995 Dec;38(6):981-7.

PMID:
8618804
26.

Mercury content of small pan fish from New York State waters.

Mills EL, Gutenmann WH, Lisk DJ.

Chemosphere. 1994 Sep;29(6):1357-9.

PMID:
7953472
27.

Applications of a beneficence.

Mills EL.

Science. 1994 Aug 26;265(5176):1253-4. No abstract available.

PMID:
17787594
28.

Urine testing in young febrile children: a risk-benefit analysis.

Kramer MS, Tange SM, Drummond KN, Mills EL.

J Pediatr. 1994 Jul;125(1):6-13.

PMID:
8021786
29.

Parents' versus physicians' values for clinical outcomes in young febrile children.

Kramer MS, Etezadi-Amoli J, Ciampi A, Tange SM, Drummond KN, Mills EL, Bernstein ML, Leduc DG.

Pediatrics. 1994 May;93(5):697-702.

PMID:
8165064
30.

Southerly enterprises.

Mills EL.

Science. 1993 May 21;260(5111):1175-6. No abstract available.

PMID:
17806358
31.

Role of the complete blood count in detecting occult focal bacterial infection in the young febrile child.

Kramer MS, Tange SM, Mills EL, Ciampi A, Bernstein ML, Drummond KN.

J Clin Epidemiol. 1993 Apr;46(4):349-57.

PMID:
8482999
32.

The sequelae of Haemophilus influenzae meningitis in school-age children.

Taylor HG, Mills EL, Ciampi A, du Berger R, Watters GV, Gold R, MacDonald N, Michaels RH.

N Engl J Med. 1990 Dec 13;323(24):1657-63.

34.

Epiglottitis in Canada: A multiregional review.

Law BJ, Draper D, Mills EL, Allard M, Nijssen-Jordan C, Bortolossi R, Macdonald NE, Al-Twaim AA, Albritton W, Kasian G, Rea L, Cronk S, Morris R.

Can J Infect Dis. 1990 Spring;1(1):15-22.

36.

Depression of neutrophil function induced by viruses and its role in secondary microbial infections.

Abramson JS, Mills EL.

Rev Infect Dis. 1988 Mar-Apr;10(2):326-41. Review.

PMID:
3131864
38.

Granulocyte transfusion kinetics measured by chemiluminescence, nitroblue tetrazolium reduction, and recovery of indium-111-labeled granulocytes.

Elliott GR, Clay ME, Mills EL, Abramson JS, McCullough J, Quie PG.

Transfusion. 1987 Jan-Feb;27(1):23-7.

PMID:
3810820
39.
40.

Group B streptococcal supraglottitis in a 3-month-old infant.

Lipson A, Kronick JB, Tewfik L, Mills EL.

Am J Dis Child. 1986 May;140(5):411-2. No abstract available.

PMID:
3962930
41.

Mechanisms of virus-induced immune suppression.

Wainberg MA, Mills EL.

Can Med Assoc J. 1985 Jun 1;132(11):1261-7. Review.

42.

Syndrome of inappropriate secretion of antidiuretic hormone in enteroviral meningitis.

Chemtob S, Reece ER, Mills EL.

Am J Dis Child. 1985 Mar;139(3):292-4.

PMID:
3976612
43.

Characterization of the effect of influenza virus on polymorphonuclear leukocyte membrane responses.

Abramson JS, Parce JW, Lewis JC, Lyles DS, Mills EL, Nelson RD, Bass DA.

Blood. 1984 Jul;64(1):131-8.

44.

Viral infections predisposing to bacterial infections.

Mills EL.

Annu Rev Med. 1984;35:469-79. Review.

PMID:
6326662
45.

Growth in patients with chronic granulomatous disease.

Payne NR, Hays NT, Regelmann WE, Sorenson M, Mills EL, Quie PG.

J Pediatr. 1983 Mar;102(3):397-9. No abstract available.

PMID:
6827411
46.

Mononuclear phagocytes in the newborn: their relation to the state of relative immunodeficiency.

Mills EL.

Am J Pediatr Hematol Oncol. 1983 Summer;5(2):189-98. Review.

PMID:
6351660
47.

Effect of influenza virus on phagocytic cells.

Debets-Ossenkopp Y, Mills EL, van Dijk WC, Verbrugh HA, Verhoef J.

Eur J Clin Microbiol. 1982 Jun;1(3):171-7.

PMID:
7173182
48.
49.

The effect of influenza virus on oxygen-dependent metabolism of human neutrophils.

Verhoef J, Mills EL, Debets-Ossenkopp Y, Verbrugh HA.

Adv Exp Med Biol. 1982;141:647-54. No abstract available.

PMID:
7090935
50.

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