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Items: 1 to 50 of 82

1.

Biology of Lipid Rafts: Introduction to Thematic Review Series.

Sviridov D, Miller YI.

J Lipid Res. 2019 Aug 28. pii: jlr.IN119000330. doi: 10.1194/jlr.IN119000330. [Epub ahead of print]

2.

Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells.

Mukhamedova N, Hoang A, Dragoljevic D, Dubrovsky L, Pushkarsky T, Low H, Ditiatkovski M, Fu Y, Ohkawa R, Meikle PJ, Horvath A, Brichacek B, Miller YI, Murphy A, Bukrinsky M, Sviridov D.

PLoS Pathog. 2019 Jul 25;15(7):e1007907. doi: 10.1371/journal.ppat.1007907. eCollection 2019 Jul.

3.

Regulation of lipid rafts, angiogenesis and inflammation by AIBP.

Fang L, Miller YI.

Curr Opin Lipidol. 2019 Jun;30(3):218-223. doi: 10.1097/MOL.0000000000000596.

PMID:
30985364
4.

AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate.

Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, Traver D, Cooke JP, Li W, Zon LI, Chen K, Bai Y, Fang L.

Science. 2019 Mar 8;363(6431):1085-1088. doi: 10.1126/science.aav1749. Epub 2019 Jan 31.

PMID:
30705153
5.

A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma.

Gonen A, Choi SH, Miu P, Agatisa-Boyle C, Acks D, Taylor AM, McNamara CA, Tsimikas S, Witztum JL, Miller YI.

J Lipid Res. 2019 Feb;60(2):436-445. doi: 10.1194/jlr.D090852. Epub 2018 Dec 18.

PMID:
30563909
6.

AIBP augments cholesterol efflux from alveolar macrophages to surfactant and reduces acute lung inflammation.

Choi SH, Wallace AM, Schneider DA, Burg E, Kim J, Alekseeva E, Ubags ND, Cool CD, Fang L, Suratt BT, Miller YI.

JCI Insight. 2018 Aug 23;3(16). pii: 120519. doi: 10.1172/jci.insight.120519. eCollection 2018 Aug 23.

7.

Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.

Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL.

Nature. 2018 Sep;561(7724):E43. doi: 10.1038/s41586-018-0313-x.

PMID:
30013121
8.

Targeting toll-like receptor-4 (TLR4)-an emerging therapeutic target for persistent pain states.

Bruno K, Woller SA, Miller YI, Yaksh TL, Wallace M, Beaton G, Chakravarthy K.

Pain. 2018 Oct;159(10):1908-1915. doi: 10.1097/j.pain.0000000000001306. Review.

PMID:
29889119
9.

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.

Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL.

Nature. 2018 Jun;558(7709):301-306. doi: 10.1038/s41586-018-0198-8. Epub 2018 Jun 6. Erratum in: Nature. 2018 Sep;561(7724):E43.

10.

Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription.

Wang H, Lapek J, Fujimura K, Strnadel J, Liu B, Gonzalez DJ, Zhang W, Watson F, Yu V, Liu C, Melo CM, Miller YI, Elliott KC, Cheresh DA, Klemke RL.

Cell Discov. 2018 May 29;4:26. doi: 10.1038/s41421-018-0024-3. eCollection 2018.

11.

Inhibition of Neuroinflammation by AIBP: Spinal Effects upon Facilitated Pain States.

Woller SA, Choi SH, An EJ, Low H, Schneider DA, Ramachandran R, Kim J, Bae YS, Sviridov D, Corr M, Yaksh TL, Miller YI.

Cell Rep. 2018 May 29;23(9):2667-2677. doi: 10.1016/j.celrep.2018.04.110.

12.

Graphene biointerfaces for optical stimulation of cells.

Savchenko A, Cherkas V, Liu C, Braun GB, Kleschevnikov A, Miller YI, Molokanova E.

Sci Adv. 2018 May 18;4(5):eaat0351. doi: 10.1126/sciadv.aat0351. eCollection 2018 May.

13.

Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply.

Liu C, Han T, Stachura DL, Wang H, Vaisman BL, Kim J, Klemke RL, Remaley AT, Rana TM, Traver D, Miller YI.

Nat Commun. 2018 Apr 3;9(1):1310. doi: 10.1038/s41467-018-03775-y.

14.

AIBP protects against metabolic abnormalities and atherosclerosis.

Schneider DA, Choi SH, Agatisa-Boyle C, Zhu L, Kim J, Pattison J, Sears DD, Gordts PLSM, Fang L, Miller YI.

J Lipid Res. 2018 May;59(5):854-863. doi: 10.1194/jlr.M083618. Epub 2018 Mar 20.

15.

Palmitate and minimally-modified low-density lipoprotein cooperatively promote inflammatory responses in macrophages.

Ann SJ, Kim KK, Cheon EJ, Noh HM, Hwang I, Yu JW, Park S, Kang SM, Manabe I, Miller YI, Kim S, Lee SH.

PLoS One. 2018 Mar 8;13(3):e0193649. doi: 10.1371/journal.pone.0193649. eCollection 2018.

16.

Modeling hypercholesterolemia and vascular lipid accumulation in LDL receptor mutant zebrafish.

Liu C, Kim YS, Kim J, Pattison J, Kamaid A, Miller YI.

J Lipid Res. 2018 Feb;59(2):391-399. doi: 10.1194/jlr.D081521. Epub 2017 Nov 29.

17.

Scavenger Receptor CD36 Directs Nonclassical Monocyte Patrolling Along the Endothelium During Early Atherogenesis.

Marcovecchio PM, Thomas GD, Mikulski Z, Ehinger E, Mueller KAL, Blatchley A, Wu R, Miller YI, Nguyen AT, Taylor AM, McNamara CA, Ley K, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2043-2052. doi: 10.1161/ATVBAHA.117.309123. Epub 2017 Sep 21.

18.

Prdx1 (peroxiredoxin 1) deficiency reduces cholesterol efflux via impaired macrophage lipophagic flux.

Jeong SJ, Kim S, Park JG, Jung IH, Lee MN, Jeon S, Kweon HY, Yu DY, Lee SH, Jang Y, Kang SW, Han KH, Miller YI, Park YM, Cheong C, Choi JH, Oh GT.

Autophagy. 2018;14(1):120-133. doi: 10.1080/15548627.2017.1327942. Epub 2017 Nov 25.

19.

An Official American Thoracic Society Workshop Report: Obesity and Metabolism. An Emerging Frontier in Lung Health and Disease.

Suratt BT, Ubags NDJ, Rastogi D, Tantisira KG, Marsland BJ, Petrache I, Allen JB, Bates JHT, Holguin F, McCormack MC, Michelakis ED, Black SM, Jain M, Mora AL, Natarajan V, Miller YI, Fessler MB, Birukov KG, Summer RS, Shore SA, Dixon AE; Allergy, Immunology, and Inflammation Assembly.

Ann Am Thorac Soc. 2017 Jun;14(6):1050-1059. doi: 10.1513/AnnalsATS.201703-263WS.

20.

AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling.

Mao R, Meng S, Gu Q, Araujo-Gutierrez R, Kumar S, Yan Q, Almazan F, Youker KA, Fu Y, Pownall HJ, Cooke JP, Miller YI, Fang L.

Circ Res. 2017 May 26;120(11):1727-1739. doi: 10.1161/CIRCRESAHA.116.309754. Epub 2017 Mar 21.

21.

Deficient Cholesterol Esterification in Plasma of apoc2 Knockout Zebrafish and Familial Chylomicronemia Patients.

Liu C, Gaudet D, Miller YI.

PLoS One. 2017 Jan 20;12(1):e0169939. doi: 10.1371/journal.pone.0169939. eCollection 2017.

22.

Context-Dependent Role of Oxidized Lipids and Lipoproteins in Inflammation.

Miller YI, Shyy JY.

Trends Endocrinol Metab. 2017 Feb;28(2):143-152. doi: 10.1016/j.tem.2016.11.002. Epub 2016 Dec 5. Review.

23.

Ins and outs of the ATP-binding cassette transporter A1.

Sviridov D, Miller YI.

Curr Opin Lipidol. 2016 Aug;27(4):429-30. doi: 10.1097/MOL.0000000000000321. No abstract available.

PMID:
27383285
24.

Oxidized cholesteryl esters and inflammation.

Choi SH, Sviridov D, Miller YI.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Apr;1862(4):393-397. doi: 10.1016/j.bbalip.2016.06.020. Epub 2016 Jun 29. Review.

25.

Reduction in lipoprotein-associated apoC-III levels following volanesorsen therapy: phase 2 randomized trial results.

Yang X, Lee SR, Choi YS, Alexander VJ, Digenio A, Yang Q, Miller YI, Witztum JL, Tsimikas S.

J Lipid Res. 2016 Apr;57(4):706-13. doi: 10.1194/jlr.M066399. Epub 2016 Feb 4.

26.

MD-2 binds cholesterol.

Choi SH, Kim J, Gonen A, Viriyakosol S, Miller YI.

Biochem Biophys Res Commun. 2016 Feb 19;470(4):877-80. doi: 10.1016/j.bbrc.2016.01.126. Epub 2016 Jan 22.

27.

Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia.

Liu C, Gates KP, Fang L, Amar MJ, Schneider DA, Geng H, Huang W, Kim J, Pattison J, Zhang J, Witztum JL, Remaley AT, Dong PD, Miller YI.

Dis Model Mech. 2015 Aug 1;8(8):989-98. doi: 10.1242/dmm.019836. Epub 2015 Jun 4.

28.

Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development.

Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC.

Dev Biol. 2015 Aug 15;404(2):49-60. doi: 10.1016/j.ydbio.2015.05.011. Epub 2015 May 22.

29.

SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL.

Choi SH, Gonen A, Diehl CJ, Kim J, Almazan F, Witztum JL, Miller YI.

Autophagy. 2015;11(5):785-95. doi: 10.1080/15548627.2015.1037061.

30.

Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92a.

Chen Z, Wen L, Martin M, Hsu CY, Fang L, Lin FM, Lin TY, Geary MJ, Geary GG, Zhao Y, Johnson DA, Chen JW, Lin SJ, Chien S, Huang HD, Miller YI, Huang PH, Shyy JY.

Circulation. 2015 Mar 3;131(9):805-14. doi: 10.1161/CIRCULATIONAHA.114.013675. Epub 2014 Dec 30.

31.

Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.

Lazic M, Inzaugarat ME, Povero D, Zhao IC, Chen M, Nalbandian M, Miller YI, Cherñavsky AC, Feldstein AE, Sears DD.

PLoS One. 2014 Sep 24;9(9):e107658. doi: 10.1371/journal.pone.0107658. eCollection 2014.

32.

Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis.

Ai D, Jiang H, Westerterp M, Murphy AJ, Wang M, Ganda A, Abramowicz S, Welch C, Almazan F, Zhu Y, Miller YI, Tall AR.

Circ Res. 2014 May 9;114(10):1576-84. doi: 10.1161/CIRCRESAHA.114.302313. Epub 2014 Mar 31.

33.

Release and capture of bioactive oxidized phospholipids and oxidized cholesteryl esters during percutaneous coronary and peripheral arterial interventions in humans.

Ravandi A, Leibundgut G, Hung MY, Patel M, Hutchins PM, Murphy RC, Prasad A, Mahmud E, Miller YI, Dennis EA, Witztum JL, Tsimikas S.

J Am Coll Cardiol. 2014 May 20;63(19):1961-71. doi: 10.1016/j.jacc.2014.01.055. Epub 2014 Mar 5.

34.

Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages.

Choi SH, Yin H, Ravandi A, Armando A, Dumlao D, Kim J, Almazan F, Taylor AM, McNamara CA, Tsimikas S, Dennis EA, Witztum JL, Miller YI.

PLoS One. 2013 Dec 23;8(12):e83145. doi: 10.1371/journal.pone.0083145. eCollection 2013.

35.

Zebrafish models of dyslipidemia: relevance to atherosclerosis and angiogenesis.

Fang L, Liu C, Miller YI.

Transl Res. 2014 Feb;163(2):99-108. doi: 10.1016/j.trsl.2013.09.004. Epub 2013 Oct 2. Review.

36.

Targeted cholesterol efflux.

Fang L, Miller YI.

Cell Cycle. 2013 Nov 1;12(21):3345-6. doi: 10.4161/cc.26401. Epub 2013 Sep 13. No abstract available.

37.

Oxidation-specific epitopes as targets for biotheranostic applications in humans: biomarkers, molecular imaging and therapeutics.

Miller YI, Tsimikas S.

Curr Opin Lipidol. 2013 Oct;24(5):426-37. doi: 10.1097/MOL.0b013e328364e85a. Review.

38.

Control of angiogenesis by AIBP-mediated cholesterol efflux.

Fang L, Choi SH, Baek JS, Liu C, Almazan F, Ulrich F, Wiesner P, Taleb A, Deer E, Pattison J, Torres-Vázquez J, Li AC, Miller YI.

Nature. 2013 Jun 6;498(7452):118-22. doi: 10.1038/nature12166. Epub 2013 May 29.

39.

MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma.

Wiesner P, Tafelmeier M, Chittka D, Choi SH, Zhang L, Byun YS, Almazan F, Yang X, Iqbal N, Chowdhury P, Maisel A, Witztum JL, Handel TM, Tsimikas S, Miller YI.

J Lipid Res. 2013 Jul;54(7):1877-83. doi: 10.1194/jlr.M036343. Epub 2013 May 10. Erratum in: J Lipid Res. 2014 Jul;55(7):1549.

40.

Emerging applications for zebrafish as a model organism to study oxidative mechanisms and their roles in inflammation and vascular accumulation of oxidized lipids.

Fang L, Miller YI.

Free Radic Biol Med. 2012 Oct 1;53(7):1411-20. doi: 10.1016/j.freeradbiomed.2012.08.004. Epub 2012 Aug 11. Review.

41.

Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis.

Koltsova EK, Garcia Z, Chodaczek G, Landau M, McArdle S, Scott SR, von Vietinghoff S, Galkina E, Miller YI, Acton ST, Ley K.

J Clin Invest. 2012 Sep;122(9):3114-26. doi: 10.1172/JCI61758. Epub 2012 Aug 13.

42.

The SYK side of TLR4: signalling mechanisms in response to LPS and minimally oxidized LDL.

Miller YI, Choi SH, Wiesner P, Bae YS.

Br J Pharmacol. 2012 Nov;167(5):990-9. doi: 10.1111/j.1476-5381.2012.02097.x. Review.

43.

Ezetimibe and simvastatin reduce cholesterol levels in zebrafish larvae fed a high-cholesterol diet.

Baek JS, Fang L, Li AC, Miller YI.

Cholesterol. 2012;2012:564705. doi: 10.1155/2012/564705. Epub 2012 May 30.

44.

The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis.

Barish GD, Yu RT, Karunasiri MS, Becerra D, Kim J, Tseng TW, Tai LJ, Leblanc M, Diehl C, Cerchietti L, Miller YI, Witztum JL, Melnick AM, Dent AL, Tangirala RK, Evans RM.

Cell Metab. 2012 Apr 4;15(4):554-62. doi: 10.1016/j.cmet.2012.02.012. Epub 2012 Mar 29.

45.

Spleen tyrosine kinase regulates AP-1 dependent transcriptional response to minimally oxidized LDL.

Choi SH, Wiesner P, Almazan F, Kim J, Miller YI.

PLoS One. 2012;7(2):e32378. doi: 10.1371/journal.pone.0032378. Epub 2012 Feb 22.

46.

Palmitate promotes the paracrine effects of macrophages on vascular smooth muscle cells: the role of bone morphogenetic proteins.

Chung JH, Jeon HJ, Hong SY, Lee DL, Lee KH, Kim SH, Han YS, Manabe I, Miller YI, Lee SH.

PLoS One. 2012;7(2):e29100. doi: 10.1371/journal.pone.0029100. Epub 2012 Feb 21.

47.

In vivo detection of oxidation-specific epitopes in atherosclerotic lesions using biocompatible manganese molecular magnetic imaging probes.

Briley-Saebo KC, Nguyen TH, Saeboe AM, Cho YS, Ryu SK, Volkova ER, Dickson S, Leibundgut G, Wiesner P, Green S, Casanada F, Miller YI, Shaw W, Witztum JL, Fayad ZA, Tsimikas S.

J Am Coll Cardiol. 2012 Feb 7;59(6):616-26. doi: 10.1016/j.jacc.2011.10.881. Erratum in: J Am Coll Cardiol. 2012 Mar 13;59(11):1043. Volkava, Eugenia [corrected to Volkova, Eugenia R]; Weisner, Philipp [corrected to Wiesner, Philipp].

48.

In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish.

Fang L, Green SR, Baek JS, Lee SH, Ellett F, Deer E, Lieschke GJ, Witztum JL, Tsimikas S, Miller YI.

J Clin Invest. 2011 Dec;121(12):4861-9. doi: 10.1172/JCI57755. Epub 2011 Nov 21.

49.

Monocyte and macrophage dynamics during atherogenesis.

Ley K, Miller YI, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1506-16. doi: 10.1161/ATVBAHA.110.221127. Review.

50.

Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity.

Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL.

Circ Res. 2011 Jan 21;108(2):235-48. doi: 10.1161/CIRCRESAHA.110.223875. Review.

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