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Items: 1 to 50 of 243

1.

A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling.

Koch PD, Miller HR, Yu G, Tallarico JA, Sorger PK, Wang Y, Feng Y, Thomas JR, Ross NT, Mitchison T.

ACS Chem Biol. 2018 Apr 20;13(4):1066-1081. doi: 10.1021/acschembio.7b01060. Epub 2018 Mar 19.

2.

Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex.

Carelli JD, Sethofer SG, Smith GA, Miller HR, Simard JL, Merrick WC, Jain RK, Ross NT, Taunton J.

Elife. 2015 Dec 10;4. pii: e10222. doi: 10.7554/eLife.10222.

3.

Novel Firmicutes group implicated in the dechlorination of two chlorinated xanthones, analogues of natural organochlorines.

Krzmarzick MJ, Miller HR, Yan T, Novak PJ.

Appl Environ Microbiol. 2014 Feb;80(3):1210-8. doi: 10.1128/AEM.03472-13. Epub 2013 Dec 2.

4.

PCR-less DNA co-polymerization detection of Shiga like toxin 1 (stx1) in Escherichia coli O157:H7.

Anderson MJ, Miller HR, Alocilja EC.

Biosens Bioelectron. 2013 Apr 15;42:581-5. doi: 10.1016/j.bios.2012.09.068. Epub 2012 Oct 9.

PMID:
23261692
5.

Novel gene expression responses in the ovine abomasal mucosa to infection with the gastric nematode Teladorsagia circumcincta.

Knight PA, Griffith SE, Pemberton AD, Pate JM, Guarneri L, Anderson K, Talbot RT, Smith S, Waddington D, Fell M, Archibald AL, Burgess ST, Smith DW, Miller HR, Morrison IW.

Vet Res. 2011 Jun 17;42:78. doi: 10.1186/1297-9716-42-78.

6.

Impairment of intestinal barrier and secretory function as well as egg excretion during intestinal schistosomiasis occur independently of mouse mast cell protease-1.

Rychter JW, Van Nassauw L, Brown JK, Van Marck E, Knight PA, Miller HR, Kroese AB, Timmermans JP.

Parasite Immunol. 2010 Apr;32(4):221-31. doi: 10.1111/j.1365-3024.2009.01182.x.

7.

Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.

Varma MV, Obach RS, Rotter C, Miller HR, Chang G, Steyn SJ, El-Kattan A, Troutman MD.

J Med Chem. 2010 Feb 11;53(3):1098-108. doi: 10.1021/jm901371v.

PMID:
20070106
8.

Expression of three intelectins in sheep and response to a Th2 environment.

French AT, Knight PA, Smith WD, Pate JA, Miller HR, Pemberton AD.

Vet Res. 2009 Nov-Dec;40(6):53. doi: 10.1051/vetres/2009035. Epub 2009 Jun 24.

9.

Physicochemical determinants of human renal clearance.

Varma MV, Feng B, Obach RS, Troutman MD, Chupka J, Miller HR, El-Kattan A.

J Med Chem. 2009 Aug 13;52(15):4844-52. doi: 10.1021/jm900403j.

PMID:
19445515
10.

Proteomic approach to identify candidate effector molecules during the in vitro immune exclusion of infective Teladorsagia circumcincta in the abomasum of sheep.

Athanasiadou S, Pemberton A, Jackson F, Inglis N, Miller HR, Thévenod F, Mackellar A, Huntley JF.

Vet Res. 2008 Nov-Dec;39(6):58. doi: 10.1051/vetres:2008035. Epub 2008 Aug 22.

11.

Reproduction and development of Russian wheat aphid biotype 2 on crested wheatgrass, intermediate wheatgrass, and susceptible and resistant wheat.

Merrill SC, Peairs FB, Miller HR, Randolph TL, Rudolph JB, Talmich EE.

J Econ Entomol. 2008 Apr;101(2):541-5.

PMID:
18459422
12.

The inner jet of an active galactic nucleus as revealed by a radio-to-gamma-ray outburst.

Marscher AP, Jorstad SG, D'Arcangelo FD, Smith PS, Williams GG, Larionov VM, Oh H, Olmstead AR, Aller MF, Aller HD, McHardy IM, Lähteenmäki A, Tornikoski M, Valtaoja E, Hagen-Thorn VA, Kopatskaya EN, Gear WK, Tosti G, Kurtanidze O, Nikolashvili M, Sigua L, Miller HR, Ryle WT.

Nature. 2008 Apr 24;452(7190):966-9. doi: 10.1038/nature06895.

13.

Extended cleavage specificity of mMCP-1, the major mucosal mast cell protease in mouse-high specificity indicates high substrate selectivity.

Andersson MK, Pemberton AD, Miller HR, Hellman L.

Mol Immunol. 2008 May;45(9):2548-58. doi: 10.1016/j.molimm.2008.01.012. Epub 2008 Mar 3.

PMID:
18313755
14.

Trichinella spiralis induces de novo expression of group IVC phospholipase A2 in the intestinal epithelium.

Brown JK, Knight PA, Thornton EM, Pate JA, Coonrod S, Miller HR, Pemberton AD.

Int J Parasitol. 2008 Feb;38(2):143-7. Epub 2007 Oct 12.

PMID:
18001740
15.

Up-regulation of intelectin in sheep after infection with Teladorsagia circumcincta.

French AT, Knight PA, Smith WD, Brown JK, Craig NM, Pate JA, Miller HR, Pemberton AD.

Int J Parasitol. 2008 Mar;38(3-4):467-75. Epub 2007 Oct 1.

PMID:
17983620
16.

The expression of intelectin in sheep goblet cells and upregulation by interleukin-4.

French AT, Bethune JA, Knight PA, McNeilly TN, Wattegedera S, Rhind S, Miller HR, Pemberton AD.

Vet Immunol Immunopathol. 2007 Nov 15;120(1-2):41-6. Epub 2007 Jul 25.

PMID:
17727963
17.

Cytokine expression in naïve and previously infected lambs after challenge with Teladorsagia circumcincta.

Craig NM, Miller HR, Smith WD, Knight PA.

Vet Immunol Immunopathol. 2007 Nov 15;120(1-2):47-54. Epub 2007 Jul 17.

PMID:
17714792
18.
19.
20.

Apical junction complex protein expression in the canine colon: differential expression of claudin-2 in the colonic mucosa in dogs with idiopathic colitis.

Ridyard AE, Brown JK, Rhind SM, Else RW, Simpson JW, Miller HR.

J Histochem Cytochem. 2007 Oct;55(10):1049-58. Epub 2007 Jun 26.

PMID:
17595339
21.

Lymphocyte-independent connective tissue mast cells populate murine synovium.

Shin K, Gurish MF, Friend DS, Pemberton AD, Thornton EM, Miller HR, Lee DM.

Arthritis Rheum. 2006 Sep;54(9):2863-71.

22.

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract.

Owyang AM, Zaph C, Wilson EH, Guild KJ, McClanahan T, Miller HR, Cua DJ, Goldschmidt M, Hunter CA, Kastelein RA, Artis D.

J Exp Med. 2006 Apr 17;203(4):843-9. Epub 2006 Apr 10.

23.

Integrin-alphavbeta6, a putative receptor for foot-and-mouth disease virus, is constitutively expressed in ruminant airways.

Brown JK, McAleese SM, Thornton EM, Pate JA, Schock A, Macrae AI, Scott PR, Miller HR, Collie DD.

J Histochem Cytochem. 2006 Jul;54(7):807-16. Epub 2006 Mar 3.

PMID:
16517977
24.
25.

The proteome of mouse mucosal mast cell homologues: the role of transforming growth factor beta1.

Pemberton AD, Brown JK, Wright SH, Knight PA, Miller HR.

Proteomics. 2006 Jan;6(2):623-31.

PMID:
16342142
26.

Cloning and expression of the extra-cellular part of the alpha chain of the equine high-affinity IgE receptor and its use in the detection of IgE.

McAleese SM, Brown JK, Macrae AI, Mackellar A, Huntley JF, Miller HR.

Vet Immunol Immunopathol. 2006 Mar 15;110(1-2):187-91. Epub 2005 Oct 7.

PMID:
16216338
27.

Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors.

Weller CL, Collington SJ, Brown JK, Miller HR, Al-Kashi A, Clark P, Jose PJ, Hartnell A, Williams TJ.

J Exp Med. 2005 Jun 20;201(12):1961-71. Epub 2005 Jun 13.

28.

Characterisation of lesional infiltrates of dendritic cells and T cell subtypes during primary infestation of sheep with Psoroptes ovis, the sheep scab mite.

van den Broek AH, Huntley JF, Mackellar A, Machell J, Taylor MA, Miller HR.

Vet Immunol Immunopathol. 2005 May 1;105(1-2):141-50.

PMID:
15797483
29.

Early innate and longer-term adaptive cutaneous immunoinflammatory responses during primary infestation with the sheep scab mite, Psoroptes ovis.

van den Broek AH, Else RW, Huntley JF, Machell J, Taylor MA, Miller HR.

J Comp Pathol. 2004 Nov;131(4):318-29.

PMID:
15511540
30.

The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity.

Artis D, Villarino A, Silverman M, He W, Thornton EM, Mu S, Summer S, Covey TM, Huang E, Yoshida H, Koretzky G, Goldschmidt M, Wu GD, de Sauvage F, Miller HR, Saris CJ, Scott P, Hunter CA.

J Immunol. 2004 Nov 1;173(9):5626-34.

31.

Expression profiling reveals novel innate and inflammatory responses in the jejunal epithelial compartment during infection with Trichinella spiralis.

Knight PA, Pemberton AD, Robertson KA, Roy DJ, Wright SH, Miller HR.

Infect Immun. 2004 Oct;72(10):6076-86.

32.

RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract.

Artis D, Wang ML, Keilbaugh SA, He W, Brenes M, Swain GP, Knight PA, Donaldson DD, Lazar MA, Miller HR, Schad GA, Scott P, Wu GD.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13596-600. Epub 2004 Aug 30.

33.

Primary antibody-Fab fragment complexes: a flexible alternative to traditional direct and indirect immunolabeling techniques.

Brown JK, Pemberton AD, Wright SH, Miller HR.

J Histochem Cytochem. 2004 Sep;52(9):1219-30.

PMID:
15314089
34.
35.

Mouse mast cell protease-1 is required for the enteropathy induced by gastrointestinal helminth infection in the mouse.

Lawrence CE, Paterson YY, Wright SH, Knight PA, Miller HR.

Gastroenterology. 2004 Jul;127(1):155-65.

PMID:
15236182
37.
38.

In vitro activation of murine DRG neurons by CGRP-mediated mucosal mast cell degranulation.

De Jonge F, De Laet A, Van Nassauw L, Brown JK, Miller HR, van Bogaert PP, Timmermans JP, Kroese AB.

Am J Physiol Gastrointest Liver Physiol. 2004 Jul;287(1):G178-91. Epub 2004 Mar 11.

39.

IgE enhances parasite clearance and regulates mast cell responses in mice infected with Trichinella spiralis.

Gurish MF, Bryce PJ, Tao H, Kisselgof AB, Thornton EM, Miller HR, Friend DS, Oettgen HC.

J Immunol. 2004 Jan 15;172(2):1139-45.

40.

Purification and characterization of mouse mast cell proteinase-2 and the differential expression and release of mouse mast cell proteinase-1 and -2 in vivo.

Pemberton AD, Brown JK, Wright SH, Knight PA, McPhee ML, McEuen AR, Forse PA, Miller HR.

Clin Exp Allergy. 2003 Jul;33(7):1005-12.

PMID:
12859460
41.
42.

Mast cells disrupt epithelial barrier function during enteric nematode infection.

McDermott JR, Bartram RE, Knight PA, Miller HR, Garrod DR, Grencis RK.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7761-6. Epub 2003 Jun 9.

43.

Effect of intestinal inflammation on capsaicin-sensitive afferents in the ileum of Schistosoma mansoni-infected mice.

De Jonge F, Van Nassauw L, Adriaensen D, Van Meir F, Miller HR, Van Marck E, Timmermans JP.

Histochem Cell Biol. 2003 Jun;119(6):477-84. Epub 2003 May 27.

PMID:
12768286
44.

Mucosal mast cells and nematode infection: strain-specific differences in mast cell precursor frequency revisited.

Brown JK, Donaldson DS, Wright SH, Miller HR.

J Helminthol. 2003 Jun;77(2):155-61.

PMID:
12756069
45.

Cloning and sequencing of the equine and ovine high-affinity IgE receptor beta-and gamma-chain cDNA.

McAleese SM, Miller HR.

Immunogenetics. 2003 May;55(2):122-5. Epub 2003 Apr 23.

PMID:
12709836
46.

Cutaneous hypersensitivity reactions to Psoroptes ovis and Der p 1 in sheep previously infested with P. ovis--the sheep scab mite.

van den Broek AH, Huntley JF, Halliwell RE, Machell J, Taylor M, Miller HR.

Vet Immunol Immunopathol. 2003 Jan 30;91(2):105-17.

PMID:
12543547
47.

Constitutive secretion of the granule chymase mouse mast cell protease-1 and the chemokine, CCL2, by mucosal mast cell homologues.

Brown JK, Knight PA, Wright SH, Thornton EM, Miller HR.

Clin Exp Allergy. 2003 Jan;33(1):132-46.

PMID:
12534561
48.

Temporal pattern of isotype-specific antibody responses in primary and challenge infestations of sheep with Psoroptes ovis--the sheep scab mite.

van den Broek AH, Huntley JF, Machell J, Taylor MA, Miller HR.

Vet Parasitol. 2003 Feb 13;111(2-3):217-30.

PMID:
12531296
49.

TGF-beta 1 regulates adhesion of mucosal mast cell homologues to laminin-1 through expression of integrin alpha 7.

Rosbottom A, Scudamore CL, von der Mark H, Thornton EM, Wright SH, Miller HR.

J Immunol. 2002 Nov 15;169(10):5689-95.

50.

Identification of an antigen from the sheep scab mite, Psoroptes ovis, homologous with house dust mite group I allergens.

Lee AJ, Machell J, Van Den Broek AH, Nisbet AJ, Miller HR, Isaac RE, Huntley JF.

Parasite Immunol. 2002 Aug;24(8):413-22.

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