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Items: 28


Proteasome inhibition preserves longitudinal growth of denervated muscle and prevents neonatal neuromuscular contractures.

Nikolaou S, Cramer AA, Hu L, Goh Q, Millay DP, Cornwall R.

JCI Insight. 2019 Dec 5;4(23). pii: 128454. doi: 10.1172/jci.insight.128454.


Cell Fusion: Merging Membranes and Making Muscle.

Petrany MJ, Millay DP.

Trends Cell Biol. 2019 Dec;29(12):964-973. doi: 10.1016/j.tcb.2019.09.002. Epub 2019 Oct 21. Review.


Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle.

Goh Q, Song T, Petrany MJ, Cramer AA, Sun C, Sadayappan S, Lee SJ, Millay DP.

Elife. 2019 Apr 23;8. pii: e44876. doi: 10.7554/eLife.44876.


Dilated cardiomyopathy-mediated heart failure induces a unique skeletal muscle myopathy with inflammation.

Song T, Manoharan P, Millay DP, Koch SE, Rubinstein J, Heiny JA, Sadayappan S.

Skelet Muscle. 2019 Jan 24;9(1):4. doi: 10.1186/s13395-019-0189-y.


Myomaker and Myomerger Work Independently to Control Distinct Steps of Membrane Remodeling during Myoblast Fusion.

Leikina E, Gamage DG, Prasad V, Goykhberg J, Crowe M, Diao J, Kozlov MM, Chernomordik LV, Millay DP.

Dev Cell. 2018 Sep 24;46(6):767-780.e7. doi: 10.1016/j.devcel.2018.08.006. Epub 2018 Sep 6.


Myoblast fusion confusion: the resolution begins.

Sampath SC, Sampath SC, Millay DP.

Skelet Muscle. 2018 Jan 31;8(1):3. doi: 10.1186/s13395-017-0149-3. Review.


Insights into the localization and function of myomaker during myoblast fusion.

Gamage DG, Leikina E, Quinn ME, Ratinov A, Chernomordik LV, Millay DP.

J Biol Chem. 2017 Oct 20;292(42):17272-17289. doi: 10.1074/jbc.M117.811372. Epub 2017 Aug 31.


Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development.

Quinn ME, Goh Q, Kurosaka M, Gamage DG, Petrany MJ, Prasad V, Millay DP.

Nat Commun. 2017 Jun 1;8:15665. doi: 10.1038/ncomms15665.


Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy.

Goh Q, Millay DP.

Elife. 2017 Feb 10;6. pii: e20007. doi: 10.7554/eLife.20007.


In vivo myomaker-mediated heterologous fusion and nuclear reprogramming.

Mitani Y, Vagnozzi RJ, Millay DP.

FASEB J. 2017 Jan;31(1):400-411. doi: 10.1096/fj.201600945R. Epub 2016 Oct 17.


Exercise-Induced Skeletal Muscle Adaptations Alter the Activity of Adipose Progenitor Cells.

Zeve D, Millay DP, Seo J, Graff JM.

PLoS One. 2016 Mar 25;11(3):e0152129. doi: 10.1371/journal.pone.0152129. eCollection 2016.


Structure-function analysis of myomaker domains required for myoblast fusion.

Millay DP, Gamage DG, Quinn ME, Min YL, Mitani Y, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2116-21. doi: 10.1073/pnas.1600101113. Epub 2016 Feb 8.


Myomaker is essential for muscle regeneration.

Millay DP, Sutherland LB, Bassel-Duby R, Olson EN.

Genes Dev. 2014 Aug 1;28(15):1641-6. doi: 10.1101/gad.247205.114.


Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice.

Burr AR, Millay DP, Goonasekera SA, Park KH, Sargent MA, Collins J, Altamirano F, Philipson KD, Allen PD, Ma J, López JR, Molkentin JD.

Mol Cell Biol. 2014 Jun;34(11):1991-2002. doi: 10.1128/MCB.00339-14. Epub 2014 Mar 24.


Myomaker is a membrane activator of myoblast fusion and muscle formation.

Millay DP, O'Rourke JR, Sutherland LB, Bezprozvannaya S, Shelton JM, Bassel-Duby R, Olson EN.

Nature. 2013 Jul 18;499(7458):301-5. doi: 10.1038/nature12343.


Making muscle or mitochondria by selective splicing of PGC-1α.

Millay DP, Olson EN.

Cell Metab. 2013 Jan 8;17(1):3-4. doi: 10.1016/j.cmet.2012.12.008.


A mouse model of rhabdomyosarcoma originating from the adipocyte lineage.

Hatley ME, Tang W, Garcia MR, Finkelstein D, Millay DP, Liu N, Graff J, Galindo RL, Olson EN.

Cancer Cell. 2012 Oct 16;22(4):536-46. doi: 10.1016/j.ccr.2012.09.004.


Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake.

Zeve D, Seo J, Suh JM, Stenesen D, Tang W, Berglund ED, Wan Y, Williams LJ, Lim A, Martinez MJ, McKay RM, Millay DP, Olson EN, Graff JM.

Cell Metab. 2012 Apr 4;15(4):492-504. doi: 10.1016/j.cmet.2012.03.010.


CREST--a large and diverse superfamily of putative transmembrane hydrolases.

Pei J, Millay DP, Olson EN, Grishin NV.

Biol Direct. 2011 Jul 6;6:37. doi: 10.1186/1745-6150-6-37.


Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle.

Goonasekera SA, Lam CK, Millay DP, Sargent MA, Hajjar RJ, Kranias EG, Molkentin JD.

J Clin Invest. 2011 Mar;121(3):1044-52. doi: 10.1172/JCI43844.


Magnetic resonance imaging assessment of cardiac dysfunction in δ-sarcoglycan null mice.

Wansapura JP, Millay DP, Dunn RS, Molkentin JD, Benson DW.

Neuromuscul Disord. 2011 Jan;21(1):68-73. doi: 10.1016/j.nmd.2010.09.007. Epub 2010 Oct 8.


Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice.

Wissing ER, Millay DP, Vuagniaux G, Molkentin JD.

Neuromuscul Disord. 2010 Nov;20(11):753-60. doi: 10.1016/j.nmd.2010.06.016. Epub 2010 Jul 15.


Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism.

Millay DP, Goonasekera SA, Sargent MA, Maillet M, Aronow BJ, Molkentin JD.

Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19023-8. doi: 10.1073/pnas.0906591106. Epub 2009 Oct 28.


Genetic manipulation of dysferlin expression in skeletal muscle: novel insights into muscular dystrophy.

Millay DP, Maillet M, Roche JA, Sargent MA, McNally EM, Bloch RJ, Molkentin JD.

Am J Pathol. 2009 Nov;175(5):1817-23. doi: 10.2353/ajpath.2009.090107. Epub 2009 Oct 15.


Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.

Millay DP, Sargent MA, Osinska H, Baines CP, Barton ER, Vuagniaux G, Sweeney HL, Robbins J, Molkentin JD.

Nat Med. 2008 Apr;14(4):442-7. doi: 10.1038/nm1736. Epub 2008 Mar 16.


Genetic disruption of calcineurin improves skeletal muscle pathology and cardiac disease in a mouse model of limb-girdle muscular dystrophy.

Parsons SA, Millay DP, Sargent MA, Naya FJ, McNally EM, Sweeney HL, Molkentin JD.

J Biol Chem. 2007 Mar 30;282(13):10068-78. Epub 2007 Feb 7.


Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy.

Parsons SA, Millay DP, Sargent MA, McNally EM, Molkentin JD.

Am J Pathol. 2006 Jun;168(6):1975-85.


Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy.

Parsons SA, Millay DP, Wilkins BJ, Bueno OF, Tsika GL, Neilson JR, Liberatore CM, Yutzey KE, Crabtree GR, Tsika RW, Molkentin JD.

J Biol Chem. 2004 Jun 18;279(25):26192-200. Epub 2004 Apr 13.

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