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Items: 13


Periprostatic Adipose Tissue Favors Prostate Cancer Cell Invasion in an Obesity-Dependent Manner: Role of Oxidative Stress.

Laurent V, Toulet A, Attané C, Milhas D, Dauvillier S, Zaidi F, Clement E, Cinato M, Le Gonidec S, Guérard A, Lehuédé C, Garandeau D, Nieto L, Renaud-Gabardos E, Prats AC, Valet P, Malavaud B, Muller C.

Mol Cancer Res. 2019 Mar;17(3):821-835. doi: 10.1158/1541-7786.MCR-18-0748. Epub 2019 Jan 3.


Metabolic remodeling induced by adipocytes: a new Achilles' heel in invasive breast cancer?

Attane C, Milhas D, Hoy AJ, Muller C.

Curr Med Chem. 2018 Apr 26. doi: 10.2174/0929867325666180426165001. [Epub ahead of print]


Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells.

Wang YY, Attané C, Milhas D, Dirat B, Dauvillier S, Guerard A, Gilhodes J, Lazar I, Alet N, Laurent V, Le Gonidec S, Biard D, Hervé C, Bost F, Ren GS, Bono F, Escourrou G, Prentki M, Nieto L, Valet P, Muller C.

JCI Insight. 2017 Feb 23;2(4):e87489. doi: 10.1172/jci.insight.87489.


Adipocyte Exosomes Promote Melanoma Aggressiveness through Fatty Acid Oxidation: A Novel Mechanism Linking Obesity and Cancer.

Lazar I, Clement E, Dauvillier S, Milhas D, Ducoux-Petit M, LeGonidec S, Moro C, Soldan V, Dalle S, Balor S, Golzio M, Burlet-Schiltz O, Valet P, Muller C, Nieto L.

Cancer Res. 2016 Jul 15;76(14):4051-7. doi: 10.1158/0008-5472.CAN-16-0651. Epub 2016 May 23.


Microenvironment mesenchymal cells protect ovarian cancer cell lines from apoptosis by inhibiting XIAP inactivation.

Castells M, Milhas D, Gandy C, Thibault B, Rafii A, Delord JP, Couderc B.

Cell Death Dis. 2013 Oct 31;4:e887. doi: 10.1038/cddis.2013.384.


The tricyclodecan-9-yl-xanthogenate D609 triggers ceramide increase and enhances FasL-induced caspase-dependent and -independent cell death in T lymphocytes.

Milhas D, Andrieu-Abadie N, Levade T, Benoist H, Ségui B.

Int J Mol Sci. 2012;13(7):8834-52. doi: 10.3390/ijms13078834. Epub 2012 Jul 16.


Caspase-10-dependent cell death in Fas/CD95 signalling is not abrogated by caspase inhibitor zVAD-fmk.

Lafont E, Milhas D, Teissié J, Therville N, Andrieu-Abadie N, Levade T, Benoist H, Ségui B.

PLoS One. 2010 Oct 26;5(10):e13638. doi: 10.1371/journal.pone.0013638.


Anterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane.

Milhas D, Clarke CJ, Idkowiak-Baldys J, Canals D, Hannun YA.

Biochim Biophys Acta. 2010 Dec;1801(12):1361-74. doi: 10.1016/j.bbalip.2010.08.001. Epub 2010 Aug 14.


Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids.

Milhas D, Clarke CJ, Hannun YA.

FEBS Lett. 2010 May 3;584(9):1887-94. doi: 10.1016/j.febslet.2009.10.058. Epub 2009 Oct 24. Review.


Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death.

Lafont E, Milhas D, Carpentier S, Garcia V, Jin ZX, Umehara H, Okazaki T, Schulze-Osthoff K, Levade T, Benoist H, Ségui B.

Cell Death Differ. 2010 Apr;17(4):642-54. doi: 10.1038/cdd.2009.130. Epub 2009 Sep 25.


Functions of sphingolipid metabolism in mammals--lessons from genetic defects.

Sabourdy F, Kedjouar B, Sorli SC, Colié S, Milhas D, Salma Y, Levade T.

Biochim Biophys Acta. 2008 Apr;1781(4):145-83. doi: 10.1016/j.bbalip.2008.01.004. Epub 2008 Feb 2. Review.


Caspase-dependent and -independent cell death of Jurkat human leukemia cells induced by novel synthetic ceramide analogs.

Granot T, Milhas D, Carpentier S, Dagan A, Ségui B, Gatt S, Levade T.

Leukemia. 2006 Mar;20(3):392-9.


Caspase-10 triggers Bid cleavage and caspase cascade activation in FasL-induced apoptosis.

Milhas D, Cuvillier O, Therville N, Clavé P, Thomsen M, Levade T, Benoist H, Ségui B.

J Biol Chem. 2005 May 20;280(20):19836-42. Epub 2005 Mar 16.

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