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Items: 6


The FOXM1 Inhibitor RCM-1 Decreases Carcinogenesis and Nuclear β-Catenin.

Shukla S, Milewski D, Pradhan A, Rama N, Rice K, Le T, Flick MJ, Vaz S, Zhao X, Setchell KD, Logarinho E, Kalinichenko VV, Kalin TV.

Mol Cancer Ther. 2019 Jul;18(7):1217-1229. doi: 10.1158/1535-7163.MCT-18-0709. Epub 2019 Apr 30.


Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppress MPNST Growth via JNK.

Ramkissoon A, Chaney KE, Milewski D, Williams KB, Williams RL, Choi K, Miller A, Kalin TV, Pressey JG, Szabo S, Azam M, Largaespada DA, Ratner N.

Clin Cancer Res. 2019 Jul 1;25(13):4117-4127. doi: 10.1158/1078-0432.CCR-18-3224. Epub 2019 Apr 1.


FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts.

Black M, Milewski D, Le T, Ren X, Xu Y, Kalinichenko VV, Kalin TV.

Cell Rep. 2018 Apr 10;23(2):442-458. doi: 10.1016/j.celrep.2018.03.067.


FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas.

Milewski D, Balli D, Ustiyan V, Le T, Dienemann H, Warth A, Breuhahn K, Whitsett JA, Kalinichenko VV, Kalin TV.

PLoS Genet. 2017 Dec 21;13(12):e1007097. doi: 10.1371/journal.pgen.1007097. eCollection 2017 Dec.


FoxF1 and FoxF2 transcription factors synergistically promote rhabdomyosarcoma carcinogenesis by repressing transcription of p21Cip1 CDK inhibitor.

Milewski D, Pradhan A, Wang X, Cai Y, Le T, Turpin B, Kalinichenko VV, Kalin TV.

Oncogene. 2017 Feb 9;36(6):850-862. doi: 10.1038/onc.2016.254. Epub 2016 Jul 18.


The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5.

Fulford L, Milewski D, Ustiyan V, Ravishankar N, Cai Y, Le T, Masineni S, Kasper S, Aronow B, Kalinichenko VV, Kalin TV.

Sci Signal. 2016 May 10;9(427):ra48. doi: 10.1126/scisignal.aad5582.


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