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Items: 1 to 50 of 74

1.

CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide.

Radhakrishnan SV, Luetkens T, Scherer SD, Davis P, Vander Mause ER, Olson ML, Yousef S, Panse J, Abdiche Y, Li KD, Miles RR, Matsui W, Welm AL, Atanackovic D.

Nat Commun. 2020 Feb 7;11(1):798. doi: 10.1038/s41467-020-14619-z.

2.

Cutaneous T-Cell Acute Lymphoblastic Leukemia and the Expression Pattern of Terminal Deoxynucleotidyl Transferase Immunostaining in Mycosis Fungoides and Spongiotic Dermatitis.

Clark JJ, Hawkes JE, Florell SR, Miles RR, Wada DA.

Dermatopathology (Basel). 2019 Sep 4;6(3):182-188. doi: 10.1159/000501581. eCollection 2019 Jul-Sep.

3.

The whole-genome landscape of Burkitt lymphoma subtypes.

Panea RI, Love CL, Shingleton JR, Reddy A, Bailey JA, Moormann AM, Otieno JA, Ong'echa JM, Oduor CI, Schroeder KMS, Masalu N, Chao NJ, Agajanian M, Major MB, Fedoriw Y, Richards KL, Rymkiewicz G, Miles RR, Alobeid B, Bhagat G, Flowers CR, Ondrejka SL, Hsi ED, Choi WWL, Au-Yeung RKH, Hartmann W, Lenz G, Meyerson H, Lin YY, Zhuang Y, Luftig MA, Waldrop A, Dave T, Thakkar D, Sahay H, Li G, Palus BC, Seshadri V, Kim SY, Gascoyne RD, Levy S, Mukhopadyay M, Dunson DB, Dave SS.

Blood. 2019 Nov 7;134(19):1598-1607. doi: 10.1182/blood.2019001880.

PMID:
31558468
4.

Transcription factor Oct1 protects against hematopoietic stress and promotes acute myeloid leukemia.

Jafek JL, Shakya A, Tai PY, Ibarra A, Kim H, Maddox J, Chumley J, Spangrude GJ, Miles RR, Kelley TW, Tantin D.

Exp Hematol. 2019 Aug;76:38-48.e2. doi: 10.1016/j.exphem.2019.07.002. Epub 2019 Jul 8.

PMID:
31295506
5.

Lysozyme nephropathy in chronic myelomonocytic leukemia.

Patel AB, Miles RR, Deininger MW.

Clin Case Rep. 2019 May 10;7(6):1263-1264. doi: 10.1002/ccr3.2188. eCollection 2019 Jun.

6.

IRF4 translocation status in pediatric follicular and diffuse large B-cell lymphoma patients enrolled in Children's Oncology Group trials.

Chisholm KM, Mohlman J, Liew M, Termuhlen A, Cairo MS, Gross TG, Perkins SL, Miles RR.

Pediatr Blood Cancer. 2019 Aug;66(8):e27770. doi: 10.1002/pbc.27770. Epub 2019 Apr 22.

PMID:
31012208
7.

Lymphoma diagnostics: getting more from less.

Galardy PJ, Bedekovics T, Macintyre E, Miles RR.

Br J Haematol. 2019 Jun;185(6):1136-1141. doi: 10.1111/bjh.15788. Epub 2019 Feb 19. Review.

PMID:
30784044
8.

ACCELERATE and European Medicine Agency Paediatric Strategy Forum for medicinal product development for mature B-cell malignancies in children.

Pearson ADJ, Scobie N, Norga K, Ligas F, Chiodin D, Burke A, Minard-Colin V, Adamson P, Marshall LV, Balakumaran A, Benettaib B, Bhargava P, Bollard CM, Bolotin E, Bomken S, Buechner J, Burkhardt B, Caron H, Copland C, Demolis P, Egorov A, Farhan M, Zugmaier G, Gross T, Horton-Taylor D, Klapper W, Lesa G, Marcus R, Miles RR, Nottage K, Pacaud L, Ricafort R, Schrappe M, Sterba J, Vezan R, Weiner S, Kim SY, Reaman G, Vassal G.

Eur J Cancer. 2019 Mar;110:74-85. doi: 10.1016/j.ejca.2019.01.013. Epub 2019 Feb 14.

PMID:
30772656
9.

Ominous cutaneous presentation of acute myeloid leukemia without peripheral blood involvement upon initial presentation and relapse: case report and literature review.

Elkeeb D, Hopkins Z, Miles RR, Halwani A, Wada D.

Eur J Dermatol. 2018 Dec 1;28(6):809-817. doi: 10.1684/ejd.2018.3463. Review.

PMID:
30698150
10.

Nuclear-Cytoplasmic Transport Is a Therapeutic Target in Myelofibrosis.

Yan D, Pomicter AD, Tantravahi S, Mason CC, Senina AV, Ahmann JM, Wang Q, Than H, Patel AB, Heaton WL, Eiring AM, Clair PM, Gantz KC, Redwine HM, Swierczek SI, Halverson BJ, Baloglu E, Shacham S, Khorashad JS, Kelley TW, Salama ME, Miles RR, Boucher KM, Prchal JT, O'Hare T, Deininger MW.

Clin Cancer Res. 2019 Apr 1;25(7):2323-2335. doi: 10.1158/1078-0432.CCR-18-0959. Epub 2018 Dec 18.

11.

Ibrutinib significantly inhibited Bruton's tyrosine kinase (BTK) phosphorylation,in-vitro proliferation and enhanced overall survival in a preclinical Burkitt lymphoma (BL) model.

Chu Y, Lee S, Shah T, Yin C, Barth M, Miles RR, Ayello J, Morris E, Harrison L, Van de Ven C, Galardy P, Goldman SC, Lim MS, Hermiston M, McAllister-Lucas LM, Giulino-Roth L, Perkins SL, Cairo MS.

Oncoimmunology. 2018 Oct 11;8(1):e1512455. doi: 10.1080/2162402X.2018.1512455. eCollection 2019.

12.

Simultaneous B and T cell acute lymphoblastic leukemias in zebrafish driven by transgenic MYC: implications for oncogenesis and lymphopoiesis.

Borga C, Park G, Foster C, Burroughs-Garcia J, Marchesin M, Shah R, Hasan A, Ahmed ST, Bresolin S, Batchelor L, Scordino T, Miles RR, Te Kronnie G, Regens JL, Frazer JK.

Leukemia. 2019 Feb;33(2):333-347. doi: 10.1038/s41375-018-0226-6. Epub 2018 Aug 15.

13.

Trends in Bone Marrow Sampling and Core Biopsy Specimen Adequacy in the United States and Canada: A Multicenter Study.

Merzianu M, Groman A, Hutson A, Cotta C, Brynes RK, Orazi A, Reddy V, Teruya-Feldstein J, Amre R, Balasubramanian M, Brandao G, Cherian S, Courville E, Czuchlewski D, Fan G, Grier D, Hoehn D, Inamdar KV, Juskevicius R, Kaur P, Lazarchick J, Lewis MR, Miles RR, Myers JB, Nasr MR, Qureishi HN, Olteanu H, Robu VG, Salaru G, Vajpayee N, Vos J, Zhang L, Zhang S, Aye L, Brega E, Coad JE, Grantham J, Ivelja S, McKenna R, Sultan K, Wilding G, Hutchison R, Peterson L, Cheney RT.

Am J Clin Pathol. 2018 Oct 1;150(5):393-405. doi: 10.1093/ajcp/aqy066.

14.

A novel AGGF1-PDGFRb fusion in pediatric T-cell acute lymphoblastic leukemia.

Zabriskie MS, Antelope O, Verma AR, Draper LR, Eide CA, Pomicter AD, Tran TH, Druker BJ, Tyner JW, Miles RR, Graham JM, Hwang JY, Varley KE, Toydemir RM, Deininger MW, Raetz EA, O'Hare T.

Haematologica. 2018 Feb;103(2):e87-e91. doi: 10.3324/haematol.2017.165282. Epub 2017 Dec 28. No abstract available.

15.

Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets.

Bouska A, Bi C, Lone W, Zhang W, Kedwaii A, Heavican T, Lachel CM, Yu J, Ferro R, Eldorghamy N, Greiner TC, Vose J, Weisenburger DD, Gascoyne RD, Rosenwald A, Ott G, Campo E, Rimsza LM, Jaffe ES, Braziel RM, Siebert R, Miles RR, Dave S, Reddy A, Delabie J, Staudt LM, Song JY, McKeithan TW, Fu K, Green M, Chan WC, Iqbal J.

Blood. 2017 Oct 19;130(16):1819-1831. doi: 10.1182/blood-2017-02-767335. Epub 2017 Aug 11.

16.

HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia.

Tharkar-Promod S, Johnson DP, Bennett SE, Dennis EM, Banowsky BG, Jones SS, Shearstone JR, Quayle SN, Min C, Jarpe M, Mosbruger T, Pomicter AD, Miles RR, Chen WY, Bhalla KN, Zweidler-McKay PA, Shrieve DC, Deininger MW, Chandrasekharan MB, Bhaskara S.

Leukemia. 2018 Jan;32(1):49-60. doi: 10.1038/leu.2017.174. Epub 2017 Jun 5.

17.

Comparative genomic expression signatures of signal transduction pathways and targets in paediatric Burkitt lymphoma: a Children's Oncology Group report.

Lee S, Day NS, Miles RR, Perkins SL, Lim MS, Ayello J, van de Ven C, Harrison L, El-Mallawany NK, Goldman S, Cairo MS.

Br J Haematol. 2017 May;177(4):601-611. doi: 10.1111/bjh.14604. Epub 2017 May 4.

18.

miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response.

Wallace JA, Kagele DA, Eiring AM, Kim CN, Hu R, Runtsch MC, Alexander M, Huffaker TB, Lee SH, Patel AB, Mosbruger TL, Voth WP, Rao DS, Miles RR, Round JL, Deininger MW, O'Connell RM.

Blood. 2017 Jun 8;129(23):3074-3086. doi: 10.1182/blood-2016-09-740209. Epub 2017 Apr 21.

19.

The effects of DLEU1 gene expression in Burkitt lymphoma (BL): potential mechanism of chemoimmunotherapy resistance in BL.

Lee S, Luo W, Shah T, Yin C, O'Connell T, Chung TH, Perkins SL, Miles RR, Ayello J, Morris E, Harrison L, van de Ven C, Cairo MS.

Oncotarget. 2017 Apr 25;8(17):27839-27853. doi: 10.18632/oncotarget.15711.

20.

Genomic analysis of adult B-ALL identifies potential markers of shorter survival.

Patel S, Mason CC, Glenn MJ, Paxton CN, South ST, Cessna MH, Asch J, Cobain EF, Bixby DL, Smith LB, Reshmi S, Gastier-Foster JM, Schiffman JD, Miles RR.

Leuk Res. 2017 May;56:44-51. doi: 10.1016/j.leukres.2017.01.034. Epub 2017 Feb 3.

PMID:
28193567
21.

Genomic characterization of pediatric B-lymphoblastic lymphoma and B-lymphoblastic leukemia using formalin-fixed tissues.

Meyer JA, Zhou D, Mason CC, Downie JM, Rodic V, Abromowitch M, Wistinghausen B, Termuhlen AM, Angiolillo AL, Perkins SL, Lones MA, Barnette P, Schiffman JD, Miles RR.

Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26363. Epub 2016 Dec 13.

PMID:
27957801
22.

MEK Inhibitors Reverse Growth of Embryonal Brain Tumors Derived from Oligoneural Precursor Cells.

Modzelewska K, Boer EF, Mosbruger TL, Picard D, Anderson D, Miles RR, Kroll M, Oslund W, Pysher TJ, Schiffman JD, Jensen R, Jette CA, Huang A, Stewart RA.

Cell Rep. 2016 Oct 25;17(5):1255-1264. doi: 10.1016/j.celrep.2016.09.081.

23.

Two Unrelated Burkitt Lymphomas Seven Years Apart in a Patient With X-Linked Lymphoproliferative Disease Type 1 (XLP1).

Zhou D, Paxton CN, Kelley TW, Afify Z, South ST, Miles RR.

Am J Clin Pathol. 2016 Aug;146(2):248-53. doi: 10.1093/ajcp/aqw036. Epub 2016 Jun 10.

PMID:
27287777
24.

Validation of break-apart and fusion MYC probes using a digital fluorescence in situ hybridization capture and imaging system.

Liew M, Rowe L, Clement PW, Miles RR, Salama ME.

J Pathol Inform. 2016 May 4;7:20. doi: 10.4103/2153-3539.181764. eCollection 2016.

25.

Molecular genetics of childhood, adolescent and young adult non-Hodgkin lymphoma.

Miles RR, Shah RK, Frazer JK.

Br J Haematol. 2016 May;173(4):582-96. doi: 10.1111/bjh.14011. Epub 2016 Mar 11. Review. Erratum in: Br J Haematol. 2016 Nov;175(3):548.

26.

Proteasome function is required for platelet production.

Shi DS, Smith MC, Campbell RA, Zimmerman PW, Franks ZB, Kraemer BF, Machlus KR, Ling J, Kamba P, Schwertz H, Rowley JW, Miles RR, Liu ZJ, Sola-Visner M, Italiano JE Jr, Christensen H, Kahr WH, Li DY, Weyrich AS.

J Clin Invest. 2014 Sep;124(9):3757-66. doi: 10.1172/JCI75247. Epub 2014 Jul 25.

27.

Secondary diffuse large B-cell lymphoma after chemotherapy for acute myeloid leukemia: looking for the unexpected diagnosis.

Ririe MR, Florell SR, Miles RR, Duffy KL.

Am J Dermatopathol. 2014 Jul;36(7):e125-8. doi: 10.1097/DAD.0000000000000027.

PMID:
24950422
28.

Primary cutaneous follicle centre lymphoma presenting as diffuse facial erythema.

Wada C, Glenn MJ, Hyde M, Powell DL, Miles RR, Duffy K, Florell SR, Wada DA.

J Eur Acad Dermatol Venereol. 2015 Apr;29(4):825-6. doi: 10.1111/jdv.12430. Epub 2014 Mar 14. No abstract available.

PMID:
24628872
29.

Aberrant expression of multiple T antigens: CD4, CD5, and CD8 on diffuse large B-cell lymphoma.

Sangle NA, Miles RR, Kelley TW, Perkins SL.

Appl Immunohistochem Mol Morphol. 2014 Nov-Dec;22(10):e45-8. doi: 10.1097/PAI.0b013e31829cc54c.

PMID:
24185124
30.

Trait stacking via targeted genome editing.

Ainley WM, Sastry-Dent L, Welter ME, Murray MG, Zeitler B, Amora R, Corbin DR, Miles RR, Arnold NL, Strange TL, Simpson MA, Cao Z, Carroll C, Pawelczak KS, Blue R, West K, Rowland LM, Perkins D, Samuel P, Dewes CM, Shen L, Sriram S, Evans SL, Rebar EJ, Zhang L, Gregory PD, Urnov FD, Webb SR, Petolino JF.

Plant Biotechnol J. 2013 Dec;11(9):1126-34. doi: 10.1111/pbi.12107. Epub 2013 Aug 19.

31.

VPREB1 deletions occur independent of lambda light chain rearrangement in childhood acute lymphoblastic leukemia.

Mangum DS, Downie J, Mason CC, Jahromi MS, Joshi D, Rodic V, Müschen M, Meeker N, Trede N, Frazer JK, Zhou Y, Cheng C, Jeha S, Pui CH, Willman CL, Harvey RC, Hunger SP, Yang JJ, Barnette P, Mullighan CG, Miles RR, Schiffman JD.

Leukemia. 2014 Jan;28(1):216-20. doi: 10.1038/leu.2013.223. Epub 2013 Jul 24. No abstract available.

32.

Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretion.

Miles RR, Perry W, Haas JV, Mosior MK, N'Cho M, Wang JW, Yu P, Calley J, Yue Y, Carter Q, Han B, Foxworthy P, Kowala MC, Ryan TP, Solenberg PJ, Michael LF.

J Biol Chem. 2013 Mar 1;288(9):6386-96. doi: 10.1074/jbc.M112.410092. Epub 2013 Jan 15.

33.

A pediatric translational perspective on the entity "progressive transformation of germinal centers (PTGC)".

Miles RR, Cairo MS.

Pediatr Blood Cancer. 2013 Jan;60(1):3-4. doi: 10.1002/pbc.24296. Epub 2012 Sep 13. No abstract available.

PMID:
22976884
34.

TP53 pathway analysis in paediatric Burkitt lymphoma reveals increased MDM4 expression as the only TP53 pathway abnormality detected in a subset of cases.

Leventaki V, Rodic V, Tripp SR, Bayerl MG, Perkins SL, Barnette P, Schiffman JD, Miles RR.

Br J Haematol. 2012 Sep;158(6):763-71. doi: 10.1111/j.1365-2141.2012.09243.x. Epub 2012 Jul 27.

PMID:
22845047
35.

Zebrafish screen identifies novel compound with selective toxicity against leukemia.

Ridges S, Heaton WL, Joshi D, Choi H, Eiring A, Batchelor L, Choudhry P, Manos EJ, Sofla H, Sanati A, Welborn S, Agarwal A, Spangrude GJ, Miles RR, Cox JE, Frazer JK, Deininger M, Balan K, Sigman M, Müschen M, Perova T, Johnson R, Montpellier B, Guidos CJ, Jones DA, Trede NS.

Blood. 2012 Jun 14;119(24):5621-31. doi: 10.1182/blood-2011-12-398818. Epub 2012 Apr 9.

36.

Risk factors and treatment of childhood and adolescent Burkitt lymphoma/leukaemia.

Miles RR, Arnold S, Cairo MS.

Br J Haematol. 2012 Mar;156(6):730-43. doi: 10.1111/j.1365-2141.2011.09024.x. Epub 2012 Jan 20. Review.

PMID:
22260323
37.

Composite mantle cell and diffuse large B-cell lymphoma: report of two cases.

Ho AK, Teman CJ, Smith GP, Nightingale DR, Miles RR.

Int J Surg Pathol. 2011 Oct;19(5):643-8. doi: 10.1177/1066896911405656.

PMID:
22090393
38.

Genome wide copy number analysis of paediatric Burkitt lymphoma using formalin-fixed tissues reveals a subset with gain of chromosome 13q and corresponding miRNA over expression.

Schiffman JD, Lorimer PD, Rodic V, Jahromi MS, Downie JM, Bayerl MG, Sanmann JN, Althof PA, Sanger WG, Barnette P, Perkins SL, Miles RR.

Br J Haematol. 2011 Nov;155(4):477-86. doi: 10.1111/j.1365-2141.2011.08883.x. Epub 2011 Oct 8.

39.

Plasmon resonant cavities in vertical nanowire arrays.

Bora M, Fasenfest BJ, Behymer EM, Chang AS, Nguyen HT, Britten JA, Larson CC, Chan JW, Miles RR, Bond TC.

Nano Lett. 2010 Aug 11;10(8):2832-7. doi: 10.1021/nl1008376.

PMID:
20698595
40.

The de-ubiquitinase UCH-L1 is an oncogene that drives the development of lymphoma in vivo by deregulating PHLPP1 and Akt signaling.

Hussain S, Foreman O, Perkins SL, Witzig TE, Miles RR, van Deursen J, Galardy PJ.

Leukemia. 2010 Sep;24(9):1641-55. doi: 10.1038/leu.2010.138. Epub 2010 Jun 24.

41.

CD56-negative extranodal nasal type NK/T-cell lymphoma.

Miles RR, Afify Z, Yaish H, Perkins SL.

Pediatr Blood Cancer. 2010 Jul 15;55(1):186-9. doi: 10.1002/pbc.22489.

PMID:
20486184
42.

Analysis of early changes in the articular cartilage transcriptisome in the rat meniscal tear model of osteoarthritis: pathway comparisons with the rat anterior cruciate transection model and with human osteoarthritic cartilage.

Wei T, Kulkarni NH, Zeng QQ, Helvering LM, Lin X, Lawrence F, Hale L, Chambers MG, Lin C, Harvey A, Ma YL, Cain RL, Oskins J, Carozza MA, Edmondson DD, Hu T, Miles RR, Ryan TP, Onyia JE, Mitchell PG.

Osteoarthritis Cartilage. 2010 Jul;18(7):992-1000. doi: 10.1016/j.joca.2010.04.012. Epub 2010 Apr 29.

43.

Expression of Grb2 distinguishes classical Hodgkin lymphomas from primary mediastinal B-cell lymphomas and other diffuse large B-cell lymphomas.

Miles RR, Mankey CC, Seiler CE 3rd, Smith LB, Teruya-Feldstein J, Hsi ED, Elenitoba-Johnson KS, Lim MS.

Hum Pathol. 2009 Dec;40(12):1731-7. doi: 10.1016/j.humpath.2009.05.009. Epub 2009 Aug 27.

PMID:
19716163
44.

Pediatric diffuse large B-cell lymphoma demonstrates a high proliferation index, frequent c-Myc protein expression, and a high incidence of germinal center subtype: Report of the French-American-British (FAB) international study group.

Miles RR, Raphael M, McCarthy K, Wotherspoon A, Lones MA, Terrier-Lacombe MJ, Patte C, Gerrard M, Auperin A, Sposto R, Davenport V, Cairo MS, Perkins SL; SFOP/LMB96/CCG5961/UKCCSG/NHL 9600 Study Group.

Pediatr Blood Cancer. 2008 Sep;51(3):369-74. doi: 10.1002/pbc.21619.

45.

Immunophenotypic identification of possible therapeutic targets in paediatric non-Hodgkin lymphomas: a children's oncology group report.

Miles RR, Cairo MS, Satwani P, Zwick DL, Lones MA, Sposto R, Abromovitch M, Tripp S, Angiolillo AL, Roman E, Davenport V, Perkins SL.

Br J Haematol. 2007 Aug;138(4):506-12.

PMID:
17659054
46.

Derivation and characterization of monoclonal antibodies against human folypolyglutamate synthetase.

Dotzlaf J, Carpenter J, Luo S, Miles RR, Fisher D, Qian YW, Ehsani M, Wang X, Lin A, McClure DB, Chen VJ, Zuckerman SH.

Hybridoma (Larchmt). 2007 Jun;26(3):155-61.

PMID:
17600497
47.

Analysis of BCL6-interacting proteins by tandem mass spectrometry.

Miles RR, Crockett DK, Lim MS, Elenitoba-Johnson KS.

Mol Cell Proteomics. 2005 Dec;4(12):1898-909. Epub 2005 Sep 6.

48.

Expression profiling of rat femur revealed suppression of bone formation genes by treatment with alendronate and estrogen but not raloxifene.

Helvering LM, Liu R, Kulkarni NH, Wei T, Chen P, Huang S, Lawrence F, Halladay DL, Miles RR, Ambrose EM, Sato M, Ma YL, Frolik CA, Dow ER, Bryant HU, Onyia JE.

Mol Pharmacol. 2005 Nov;68(5):1225-38. Epub 2005 Aug 3.

PMID:
16079270
49.

Effects of parathyroid hormone on Wnt signaling pathway in bone.

Kulkarni NH, Halladay DL, Miles RR, Gilbert LM, Frolik CA, Galvin RJ, Martin TJ, Gillespie MT, Onyia JE.

J Cell Biochem. 2005 Aug 15;95(6):1178-90.

PMID:
15962290
50.

Molecular profile of catabolic versus anabolic treatment regimens of parathyroid hormone (PTH) in rat bone: an analysis by DNA microarray.

Onyia JE, Helvering LM, Gelbert L, Wei T, Huang S, Chen P, Dow ER, Maran A, Zhang M, Lotinun S, Lin X, Halladay DL, Miles RR, Kulkarni NH, Ambrose EM, Ma YL, Frolik CA, Sato M, Bryant HU, Turner RT.

J Cell Biochem. 2005 May 15;95(2):403-18.

PMID:
15779007

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