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Items: 31


Pitx2 cholinergic interneurons are the source of C bouton synapses on brainstem motor neurons.

Rozani I, Tsapara G, Witts EC, Deaville SJ, Miles GB, Zagoraiou L.

Sci Rep. 2019 Mar 20;9(1):4936. doi: 10.1038/s41598-019-39996-4.


Modulation of spinal motor networks by astrocyte-derived adenosine is dependent on D1-like dopamine receptor signaling.

Acton D, Broadhead MJ, Miles GB.

J Neurophysiol. 2018 Sep 1;120(3):998-1009. doi: 10.1152/jn.00783.2017. Epub 2018 May 23.


C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity.

Selvaraj BT, Livesey MR, Zhao C, Gregory JM, James OT, Cleary EM, Chouhan AK, Gane AB, Perkins EM, Dando O, Lillico SG, Lee YB, Nishimura AL, Poreci U, Thankamony S, Pray M, Vasistha NA, Magnani D, Borooah S, Burr K, Story D, McCampbell A, Shaw CE, Kind PC, Aitman TJ, Whitelaw CBA, Wilmut I, Smith C, Miles GB, Hardingham GE, Wyllie DJA, Chandran S.

Nat Commun. 2018 Jan 24;9(1):347. doi: 10.1038/s41467-017-02729-0.


Gliotransmission and adenosinergic modulation: insights from mammalian spinal motor networks.

Acton D, Miles GB.

J Neurophysiol. 2017 Dec 1;118(6):3311-3327. doi: 10.1152/jn.00230.2017. Epub 2017 Sep 27. Review.


Differential regulation of NMDA receptors by d-serine and glycine in mammalian spinal locomotor networks.

Acton D, Miles GB.

J Neurophysiol. 2017 May 1;117(5):1877-1893. doi: 10.1152/jn.00810.2016. Epub 2017 Feb 15.


Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks.

Picton LD, Nascimento F, Broadhead MJ, Sillar KT, Miles GB.

J Neurosci. 2017 Jan 25;37(4):906-921. doi: 10.1523/JNEUROSCI.2005-16.2016.


Lasing in Live Mitotic and Non-Phagocytic Cells by Efficient Delivery of Microresonators.

Schubert M, Volckaert K, Karl M, Morton A, Liehm P, Miles GB, Powis SJ, Gather MC.

Sci Rep. 2017 Jan 19;7:40877. doi: 10.1038/srep40877.


Arrays of microscopic organic LEDs for high-resolution optogenetics.

Steude A, Witts EC, Miles GB, Gather MC.

Sci Adv. 2016 May 6;2(5):e1600061. doi: 10.1126/sciadv.1600061. eCollection 2016 May.


Adenosine-mediated modulation of ventral horn interneurons and spinal motoneurons in neonatal mice.

Witts EC, Nascimento F, Miles GB.

J Neurophysiol. 2015 Oct;114(4):2305-15. doi: 10.1152/jn.00574.2014. Epub 2015 Aug 26.


Stimulation of Glia Reveals Modulation of Mammalian Spinal Motor Networks by Adenosine.

Acton D, Miles GB.

PLoS One. 2015 Aug 7;10(8):e0134488. doi: 10.1371/journal.pone.0134488. eCollection 2015.


Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability.

Devlin AC, Burr K, Borooah S, Foster JD, Cleary EM, Geti I, Vallier L, Shaw CE, Chandran S, Miles GB.

Nat Commun. 2015 Jan 12;6:5999. doi: 10.1038/ncomms6999.


Nitric oxide-mediated modulation of the murine locomotor network.

Foster JD, Dunford C, Sillar KT, Miles GB.

J Neurophysiol. 2014 Feb;111(3):659-74. doi: 10.1152/jn.00378.2013. Epub 2013 Nov 20.


Fast targeted gene transfection and optogenetic modification of single neurons using femtosecond laser irradiation.

Antkowiak M, Torres-Mapa ML, Witts EC, Miles GB, Dholakia K, Gunn-Moore FJ.

Sci Rep. 2013 Nov 21;3:3281. doi: 10.1038/srep03281.


Anatomy and function of cholinergic C bouton inputs to motor neurons.

Witts EC, Zagoraiou L, Miles GB.

J Anat. 2014 Jan;224(1):52-60. doi: 10.1111/joa.12063. Epub 2013 May 23. Review. Erratum in: J Anat. 2014 Apr;224(4):528. J Anat. 2014 Apr;224(4):528.


Gender-specific perturbations in modulatory inputs to motoneurons in a mouse model of amyotrophic lateral sclerosis.

Herron LR, Miles GB.

Neuroscience. 2012 Dec 13;226:313-23. doi: 10.1016/j.neuroscience.2012.09.031. Epub 2012 Sep 19.


Glial-derived adenosine modulates spinal motor networks in mice.

Witts EC, Panetta KM, Miles GB.

J Neurophysiol. 2012 Apr;107(7):1925-34. doi: 10.1152/jn.00513.2011. Epub 2011 Dec 28.


Neuromodulation of vertebrate locomotor control networks.

Miles GB, Sillar KT.

Physiology (Bethesda). 2011 Dec;26(6):393-411. doi: 10.1152/physiol.00013.2011. Review.


Activation of group I metabotropic glutamate receptors modulates locomotor-related motoneuron output in mice.

Iwagaki N, Miles GB.

J Neurophysiol. 2011 May;105(5):2108-20. doi: 10.1152/jn.01037.2010. Epub 2011 Feb 23.


A cluster of cholinergic premotor interneurons modulates mouse locomotor activity.

Zagoraiou L, Akay T, Martin JF, Brownstone RM, Jessell TM, Miles GB.

Neuron. 2009 Dec 10;64(5):645-62. doi: 10.1016/j.neuron.2009.10.017.


Transplanted mouse embryonic stem-cell-derived motoneurons form functional motor units and reduce muscle atrophy.

Yohn DC, Miles GB, Rafuse VF, Brownstone RM.

J Neurosci. 2008 Nov 19;28(47):12409-18. doi: 10.1523/JNEUROSCI.1761-08.2008.


A multitarget basal ganglia dopaminergic and GABAergic transplantation strategy enhances behavioural recovery in parkinsonian rats.

Mukhida K, Hong M, Miles GB, Phillips T, Baghbaderani BA, McLeod M, Kobayashi N, Sen A, Behie LA, Brownstone RM, Mendez I.

Brain. 2008 Aug;131(Pt 8):2106-26. doi: 10.1093/brain/awn149. Epub 2008 Jul 18.


Spinal cholinergic interneurons regulate the excitability of motoneurons during locomotion.

Miles GB, Hartley R, Todd AJ, Brownstone RM.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2448-53. Epub 2007 Feb 7.


Motoneurons derived from embryonic stem cells express transcription factors and develop phenotypes characteristic of medial motor column neurons.

Soundararajan P, Miles GB, Rubin LL, Brownstone RM, Rafuse VF.

J Neurosci. 2006 Mar 22;26(12):3256-68.


Mechanisms underlying the early phase of spike frequency adaptation in mouse spinal motoneurones.

Miles GB, Dai Y, Brownstone RM.

J Physiol. 2005 Jul 15;566(Pt 2):519-32. Epub 2005 May 5.


Functional properties of motoneurons derived from mouse embryonic stem cells.

Miles GB, Yohn DC, Wichterle H, Jessell TM, Rafuse VF, Brownstone RM.

J Neurosci. 2004 Sep 8;24(36):7848-58.


Differential expression of voltage-activated calcium channels in III and XII motoneurones during development in the rat.

Miles GB, Lipski J, Lorier AR, Laslo P, Funk GD.

Eur J Neurosci. 2004 Aug;20(4):903-13.


Modulation of phrenic motoneuron excitability by ATP: consequences for respiratory-related output in vitro.

Miles GB, Parkis MA, Lipski J, Funk GD.

J Appl Physiol (1985). 2002 May;92(5):1899-910.


GluR2 AMPA receptor subunit expression in motoneurons at low and high risk for degeneration in amyotrophic lateral sclerosis.

Laslo P, Lipski J, Nicholson LF, Miles GB, Funk GD.

Exp Neurol. 2001 Jun;169(2):461-71.


Calcium binding proteins in motoneurons at low and high risk for degeneration in ALS.

Laslo P, Lipski J, Nicholson LF, Miles GB, Funk GD.

Neuroreport. 2000 Oct 20;11(15):3305-8.


Synaptic control of motoneuron excitability in rodents: from months to milliseconds.

Funk GD, Parkis MA, Selvaratnam SR, Robinson DM, Miles GB, Peebles KC.

Clin Exp Pharmacol Physiol. 2000 Jan-Feb;27(1-2):120-5. Review.


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