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Circulating adiposity-related microRNAs as predictors of the response to a low-fat diet in subjects with obesity.

Assmann TS, Riezu-Boj JI, Milagro FI, Martínez JA.

J Cell Mol Med. 2020 Jan 22. doi: 10.1111/jcmm.14920. [Epub ahead of print]


Biochemical profile, eating habits, and telomere length among Brazilian children and adolescents.

Todendi PF, Martínez JA, Reuter CP, Matos WL, Franke SIR, Razquin C, Milagro FI, Kahl VFS, Fiegenbaum M, Valim ARM.

Nutrition. 2019 Nov 9;71:110645. doi: 10.1016/j.nut.2019.110645. [Epub ahead of print]


Interplay of an Obesity-Based Genetic Risk Score with Dietary and Endocrine Factors on Insulin Resistance.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Cuervo M, Goni L, Martinez JA.

Nutrients. 2019 Dec 21;12(1). pii: E33. doi: 10.3390/nu12010033.


One-Carbon Metabolism and Nonalcoholic Fatty Liver Disease: The Crosstalk between Nutrients, Microbiota, and Genetics.

Radziejewska A, Muzsik A, Milagro FI, Martínez JA, Chmurzynska A.

Lifestyle Genom. 2019 Dec 17:1-11. doi: 10.1159/000504602. [Epub ahead of print] Review.


miR-1185-1 and miR-548q Are Biomarkers of Response to Weight Loss and Regulate the Expression of GSK3B.

Garcia-Lacarte M, Mansego ML, Zulet MA, Martinez JA, Milagro FI.

Cells. 2019 Nov 30;8(12). pii: E1548. doi: 10.3390/cells8121548.


Modeling of an integrative prototype based on genetic, phenotypic, and environmental information for personalized prescription of energy-restricted diets in overweight/obese subjects.

Ramos-Lopez O, Cuervo M, Goni L, Milagro FI, Riezu-Boj JI, Martinez JA.

Am J Clin Nutr. 2019 Nov 21. pii: nqz286. doi: 10.1093/ajcn/nqz286. [Epub ahead of print]


Fatty acids, epigenetic mechanisms and chronic diseases: a systematic review.

González-Becerra K, Ramos-Lopez O, Barrón-Cabrera E, Riezu-Boj JI, Milagro FI, Martínez-López E, Martínez JA.

Lipids Health Dis. 2019 Oct 15;18(1):178. doi: 10.1186/s12944-019-1120-6. Review.


Genetic and nongenetic factors explaining metabolically healthy and unhealthy phenotypes in participants with excessive adiposity: relevance for personalized nutrition.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Cuervo M, Goni L, Martinez JA.

Ther Adv Endocrinol Metab. 2019 Sep 18;10:2042018819877303. doi: 10.1177/2042018819877303. eCollection 2019.


Epigenetic Modifications as Outcomes of Exercise Interventions Related to Specific Metabolic Alterations: A Systematic Review.

Barrón-Cabrera E, Ramos-Lopez O, González-Becerra K, Riezu-Boj JI, Milagro FI, Martínez-López E, Martínez JA.

Lifestyle Genom. 2019;12(1-6):25-44. doi: 10.1159/000503289. Epub 2019 Sep 23.


Crosstalk between microRNAs, the putative target genes and the lncRNA network in metabolic diseases.

Assmann TS, Milagro FI, Martínez JA.

Mol Med Rep. 2019 Oct;20(4):3543-3554. doi: 10.3892/mmr.2019.10595. Epub 2019 Aug 21.


The regulation of inflammation-related genes after palmitic acid and DHA treatments is not mediated by DNA methylation.

Samblas M, Carraro JC, Martínez JA, Milagro FI.

J Physiol Biochem. 2019 Aug;75(3):341-349. doi: 10.1007/s13105-019-00685-5. Epub 2019 Aug 19.


Models Integrating Genetic and Lifestyle Interactions on Two Adiposity Phenotypes for Personalized Prescription of Energy-Restricted Diets With Different Macronutrient Distribution.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Cuervo M, Goni L, Martinez JA.

Front Genet. 2019 Jul 30;10:686. doi: 10.3389/fgene.2019.00686. eCollection 2019.


Interaction Among Sex, Aging, and Epigenetic Processes Concerning Visceral Fat, Insulin Resistance, and Dyslipidaemia.

Arpón A, Milagro FI, Santos JL, García-Granero M, Riezu-Boj JI, Martínez JA.

Front Endocrinol (Lausanne). 2019 Jul 17;10:496. doi: 10.3389/fendo.2019.00496. eCollection 2019.


Low doses of cocoa extract supplementation ameliorate diet-induced obesity and insulin resistance in rats.

Aranaz P, Romo-Hualde A, Navarro-Herrera D, Zabala M, López-Yoldi M, González-Ferrero C, Gil AG, Martínez JA, Vizmanos JL, Milagro FI, González-Navarro CJ.

Food Funct. 2019 Aug 1;10(8):4811-4822. doi: 10.1039/c9fo00918c. Epub 2019 Jul 18.


Oral Phenelzine Treatment Mitigates Metabolic Disturbances in Mice Fed a High-Fat Diet.

Mercader J, Sabater AG, Le Gonidec S, Decaunes P, Chaplin A, Gómez-Zorita S, Milagro FI, Carpéné C.

J Pharmacol Exp Ther. 2019 Nov;371(2):555-566. doi: 10.1124/jpet.119.259895. Epub 2019 Jul 3.


Methylome-Wide Association Study in Peripheral White Blood Cells Focusing on Central Obesity and Inflammation.

Arpón A, Milagro FI, Ramos-Lopez O, Mansego ML, Riezu-Boj JI, Martínez JA; MENA Project.

Genes (Basel). 2019 Jun 11;10(6). pii: E444. doi: 10.3390/genes10060444.


Insulin Sensitivity Is Associated with Lipoprotein Lipase (LPL) and Catenin Delta 2 (CTNND2) DNA Methylation in Peripheral White Blood Cells in Non-Diabetic Young Women.

Arpón A, Santos JL, Milagro FI, Cataldo LR, Bravo C, Riezu-Boj JI, Martínez JA.

Int J Mol Sci. 2019 Jun 15;20(12). pii: E2928. doi: 10.3390/ijms20122928.


Changes in Anxiety and Depression Traits Induced by Energy Restriction: Predictive Value of the Baseline Status.

Rodriguez-Lozada C, Cuervo M, Cuevas-Sierra A, Goni L, Riezu-Boj JI, Navas-Carretero S, Milagro FI, Martinez JA.

Nutrients. 2019 May 28;11(6). pii: E1206. doi: 10.3390/nu11061206.


Associations between olfactory pathway gene methylation marks, obesity features and dietary intakes.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Zulet MA, Santos JL, Martinez JA; MENA project.

Genes Nutr. 2019 Apr 25;14:11. doi: 10.1186/s12263-019-0635-9. eCollection 2019.


DNA methylation in genes of longevity-regulating pathways: association with obesity and metabolic complications.

Salas-Pérez F, Ramos-Lopez O, Mansego ML, Milagro FI, Santos JL, Riezu-Boj JI, Martínez JA.

Aging (Albany NY). 2019 Mar 29;11(6):1874-1899. doi: 10.18632/aging.101882.


DNA methylation markers in obesity, metabolic syndrome, and weight loss.

Samblas M, Milagro FI, Martínez A.

Epigenetics. 2019 May;14(5):421-444. doi: 10.1080/15592294.2019.1595297. Epub 2019 Mar 27.


Phenolic Compounds Inhibit 3T3-L1 Adipogenesis Depending on the Stage of Differentiation and Their Binding Affinity to PPARγ.

Aranaz P, Navarro-Herrera D, Zabala M, Miguéliz I, Romo-Hualde A, López-Yoldi M, Martínez JA, Vizmanos JL, Milagro FI, González-Navarro CJ.

Molecules. 2019 Mar 16;24(6). pii: E1045. doi: 10.3390/molecules24061045.


Plasma lactate and leukocyte mitochondrial DNA copy number as biomarkers of insulin sensitivity in non-diabetic women.

Santos JL, Cataldo LR, Cortés-Rivera C, Bravo C, Díaz-Casanova L, Martínez JA, Milagro FI, Galgani J.

J Physiol Biochem. 2019 Aug;75(3):285-297. doi: 10.1007/s13105-019-00672-w. Epub 2019 Mar 13.


Epigenome-wide association study in peripheral white blood cells involving insulin resistance.

Arpón A, Milagro FI, Ramos-Lopez O, Mansego ML, Santos JL, Riezu-Boj JI, Martínez JA.

Sci Rep. 2019 Feb 21;9(1):2445. doi: 10.1038/s41598-019-38980-2.


Diet, Gut Microbiota, and Obesity: Links with Host Genetics and Epigenetics and Potential Applications.

Cuevas-Sierra A, Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Martinez JA.

Adv Nutr. 2019 Jan 1;10(suppl_1):S17-S30. doi: 10.1093/advances/nmy078.


Association between Sleep Disturbances and Liver Status in Obese Subjects with Nonalcoholic Fatty Liver Disease: A Comparison with Healthy Controls.

Marin-Alejandre BA, Abete I, Cantero I, Riezu-Boj JI, Milagro FI, Monreal JI, Elorz M, Herrero JI, Benito-Boillos A, Quiroga J, Martinez-Echeverria A, Uriz-Otano JI, Huarte-Muniesa MP, Tur JA, Martínez JA, Zulet MA.

Nutrients. 2019 Feb 2;11(2). pii: E322. doi: 10.3390/nu11020322.


MicroRNAs and other non-coding RNAs in adipose tissue and obesity: emerging roles as biomarkers and therapeutic targets.

Lorente-Cebrián S, González-Muniesa P, Milagro FI, Martínez JA.

Clin Sci (Lond). 2019 Jan 3;133(1):23-40. doi: 10.1042/CS20180890. Print 2019 Jan 15. Review.


Prediction of Blood Lipid Phenotypes Using Obesity-Related Genetic Polymorphisms and Lifestyle Data in Subjects with Excessive Body Weight.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Cuervo M, Goni L, Martinez JA.

Int J Genomics. 2018 Nov 19;2018:4283078. doi: 10.1155/2018/4283078. eCollection 2018.


Association of Methylation Signatures at Hepatocellular Carcinoma Pathway Genes with Adiposity and Insulin Resistance Phenotypes.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Alfredo Martinez J; MENA Project.

Nutr Cancer. 2019;71(5):840-851. doi: 10.1080/01635581.2018.1531136. Epub 2018 Nov 20.


Do the Effects of Resveratrol on Thermogenic and Oxidative Capacities in IBAT and Skeletal Muscle Depend on Feeding Conditions?

Milton-Laskibar I, Aguirre L, Etxeberria U, Milagro FI, Martínez JA, Portillo MP.

Nutrients. 2018 Oct 6;10(10). pii: E1446. doi: 10.3390/nu10101446.


Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target.

Janeiro MH, Ramírez MJ, Milagro FI, Martínez JA, Solas M.

Nutrients. 2018 Oct 1;10(10). pii: E1398. doi: 10.3390/nu10101398. Review.


Implication of miR-612 and miR-1976 in the regulation of TP53 and CD40 and their relationship in the response to specific weight-loss diets.

Garcia-Lacarte M, Martinez JA, Zulet MA, Milagro FI.

PLoS One. 2018 Aug 8;13(8):e0201217. doi: 10.1371/journal.pone.0201217. eCollection 2018.


Dopamine gene methylation patterns are associated with obesity markers and carbohydrate intake.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Martinez JA; MENA Project.

Brain Behav. 2018 Aug;8(8):e01017. doi: 10.1002/brb3.1017. Epub 2018 Jul 11.


Involvement of autophagy in the beneficial effects of resveratrol in hepatic steatosis treatment. A comparison with energy restriction.

Milton-Laskibar I, Aguirre L, Etxeberria U, Milagro FI, Martínez JA, Portillo MP.

Food Funct. 2018 Aug 15;9(8):4207-4215. doi: 10.1039/c8fo00930a.


An integrated transcriptomic and epigenomic analysis identifies CD44 gene as a potential biomarker for weight loss within an energy-restricted program.

Samblas M, Mansego ML, Zulet MA, Milagro FI, Martinez JA.

Eur J Nutr. 2019 Aug;58(5):1971-1980. doi: 10.1007/s00394-018-1750-x. Epub 2018 Jun 14.


Interaction between an ADCY3 Genetic Variant and Two Weight-Lowering Diets Affecting Body Fatness and Body Composition Outcomes Depending on Macronutrient Distribution: A Randomized Trial.

Goni L, Riezu-Boj JI, Milagro FI, Corrales FJ, Ortiz L, Cuervo M, Martínez JA.

Nutrients. 2018 Jun 19;10(6). pii: E789. doi: 10.3390/nu10060789.


Phenotype and genotype predictors of BMI variability among European adults.

Goni L, García-Granero M, Milagro FI, Cuervo M, Martínez JA.

Nutr Diabetes. 2018 May 24;8(1):27. doi: 10.1038/s41387-018-0041-1.


Regulatory roles of miR-155 and let-7b on the expression of inflammation-related genes in THP-1 cells: effects of fatty acids.

Marques-Rocha JL, Garcia-Lacarte M, Samblas M, Bressan J, Martínez JA, Milagro FI.

J Physiol Biochem. 2018 Nov;74(4):579-589. doi: 10.1007/s13105-018-0629-x. Epub 2018 May 22.


Circadian gene methylation profiles are associated with obesity, metabolic disturbances and carbohydrate intake.

Ramos-Lopez O, Samblas M, Milagro FI, Riezu-Boj JI, Crujeiras AB, Martinez JA, Project M.

Chronobiol Int. 2018 Jul;35(7):969-981. doi: 10.1080/07420528.2018.1446021. Epub 2018 Mar 26.


Endoplasmic reticulum stress epigenetics is related to adiposity, dyslipidemia, and insulin resistance.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Moreno-Aliaga MJ, Martinez JA; project MENA.

Adipocyte. 2018;7(2):137-142. doi: 10.1080/21623945.2018.1447731. Epub 2018 Mar 23. Review.


Effects of exosomes from LPS-activated macrophages on adipocyte gene expression, differentiation, and insulin-dependent glucose uptake.

De Silva N, Samblas M, Martínez JA, Milagro FI.

J Physiol Biochem. 2018 Nov;74(4):559-568. doi: 10.1007/s13105-018-0622-4. Epub 2018 Mar 20.


Association of low dietary folate intake with lower CAMKK2 gene methylation, adiposity, and insulin resistance in obese subjects.

Ramos-Lopez O, Samblas M, Milagro FI, Zulet MA, Mansego ML, Riezu-Boj JI, Martinez JA.

Nutr Res. 2018 Feb;50:53-62. doi: 10.1016/j.nutres.2017.11.007. Epub 2017 Dec 5.


Association of the Gly482Ser PPARGC1A gene variant with different cholesterol outcomes in response to two energy-restricted diets in subjects with excessive weight.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Goni L, Cuervo M, Martinez JA.

Nutrition. 2018 Mar;47:83-89. doi: 10.1016/j.nut.2017.10.008. Epub 2018 Jan 4.


Effect of hypoxia on caveolae-related protein expression and insulin signaling in adipocytes.

Varela-Guruceaga M, Milagro FI, Martínez JA, de Miguel C.

Mol Cell Endocrinol. 2018 Sep 15;473:257-267. doi: 10.1016/j.mce.2018.01.026. Epub 2018 Jan 31.


Differential lipid metabolism outcomes associated with ADRB2 gene polymorphisms in response to two dietary interventions in overweight/obese subjects.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Goni L, Cuervo M, Martinez JA.

Nutr Metab Cardiovasc Dis. 2018 Feb;28(2):165-172. doi: 10.1016/j.numecd.2017.11.006. Epub 2017 Dec 5.


Impact of Consuming Extra-Virgin Olive Oil or Nuts within a Mediterranean Diet on DNA Methylation in Peripheral White Blood Cells within the PREDIMED-Navarra Randomized Controlled Trial: A Role for Dietary Lipids.

Arpón A, Milagro FI, Razquin C, Corella D, Estruch R, Fitó M, Marti A, Martínez-González MA, Ros E, Salas-Salvadó J, Riezu-Boj JI, Martínez JA.

Nutrients. 2017 Dec 23;10(1). pii: E15. doi: 10.3390/nu10010015.


DNA methylation signatures at endoplasmic reticulum stress genes are associated with adiposity and insulin resistance.

Ramos-Lopez O, Riezu-Boj JI, Milagro FI, Martinez JA; MENA Project.

Mol Genet Metab. 2018 Jan;123(1):50-58. doi: 10.1016/j.ymgme.2017.11.011. Epub 2017 Nov 28.


Methylation changes and pathways affected in preterm birth: a role for SLC6A3 in neurodevelopment.

Arpón A, Milagro FI, Laja A, Segura V, de Pipaón MS, Riezu-Boj JI, Alfredo Martínez J.

Epigenomics. 2018 Jan;10(1):91-103. doi: 10.2217/epi-2017-0082. Epub 2017 Nov 27.


Inflammation and gut-brain axis link obesity to cognitive dysfunction: plausible pharmacological interventions.

Solas M, Milagro FI, Ramírez MJ, Martínez JA.

Curr Opin Pharmacol. 2017 Dec;37:87-92. doi: 10.1016/j.coph.2017.10.005. Epub 2017 Nov 5. Review.


Freeze-dried strawberry and blueberry attenuates diet-induced obesity and insulin resistance in rats by inhibiting adipogenesis and lipogenesis.

Aranaz P, Romo-Hualde A, Zabala M, Navarro-Herrera D, Ruiz de Galarreta M, Gil AG, Martinez JA, Milagro FI, González-Navarro CJ.

Food Funct. 2017 Nov 15;8(11):3999-4013. doi: 10.1039/c7fo00996h.


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