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Items: 9


Synthetic Lethal Strategy Identifies a Potent and Selective TTK and CLK1/2 Inhibitor for Treatment of Triple-Negative Breast Cancer with a Compromised G1-S Checkpoint.

Zhu D, Xu S, Deyanat-Yazdi G, Peng SX, Barnes LA, Narla RK, Tran T, Mikolon D, Ning Y, Shi T, Jiang N, Raymon HK, Riggs JR, Boylan JF.

Mol Cancer Ther. 2018 Aug;17(8):1727-1738. doi: 10.1158/1535-7163.MCT-17-1084. Epub 2018 Jun 4.


Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis.

Barbero S, Mielgo A, Torres V, Teitz T, Shields DJ, Mikolon D, Bogyo M, BarilĂ  D, Lahti JM, Schlaepfer D, Stupack DG.

Cancer Res. 2009 May 1;69(9):3755-63. doi: 10.1158/0008-5472.CAN-08-3937. Epub 2009 Apr 21.


FERM control of FAK function: implications for cancer therapy.

Lim ST, Mikolon D, Stupack DG, Schlaepfer DD.

Cell Cycle. 2008 Aug;7(15):2306-14. Epub 2008 May 29. Review.


Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility.

Wu L, Bernard-Trifilo JA, Lim Y, Lim ST, Mitra SK, Uryu S, Chen M, Pallen CJ, Cheung NK, Mikolon D, Mielgo A, Stupack DG, Schlaepfer DD.

Oncogene. 2008 Feb 28;27(10):1439-48. Epub 2007 Sep 10.


Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor.

Nasimuzzaman M, Waris G, Mikolon D, Stupack DG, Siddiqui A.

J Virol. 2007 Oct;81(19):10249-57. Epub 2007 Jul 11.


Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors.

Mitra SK, Mikolon D, Molina JE, Hsia DA, Hanson DA, Chi A, Lim ST, Bernard-Trifilo JA, Ilic D, Stupack DG, Cheresh DA, Schlaepfer DD.

Oncogene. 2006 Sep 28;25(44):5969-84. Epub 2006 May 8.


Potentiation of neuroblastoma metastasis by loss of caspase-8.

Stupack DG, Teitz T, Potter MD, Mikolon D, Houghton PJ, Kidd VJ, Lahti JM, Cheresh DA.

Nature. 2006 Jan 5;439(7072):95-9.


Angiogenesis assays in the chick CAM.

Storgard C, Mikolon D, Stupack DG.

Methods Mol Biol. 2005;294:123-36.


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