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Items: 21

1.

Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis.

Li JY, Miklossy G, Modukuri RK, Bohren KM, Yu Z, Palaniappan M, Faver JC, Riehle K, Matzuk MM, Simmons N.

Bioconjug Chem. 2019 Aug 21;30(8):2209-2215. doi: 10.1021/acs.bioconjchem.9b00447. Epub 2019 Jul 31.

2.

Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity.

Goebel EJ, Corpina RA, Hinck CS, Czepnik M, Castonguay R, Grenha R, Boisvert A, Miklossy G, Fullerton PT, Matzuk MM, Idone VJ, Economides AN, Kumar R, Hinck AP, Thompson TB.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15505-15513. doi: 10.1073/pnas.1906253116. Epub 2019 Jul 17.

PMID:
31315975
3.

Bioactive polyprenylated benzophenone derivatives from the fruits extracts of Garcinia xanthochymus.

Youn UJ, Sripisut T, Miklossy G, Turkson J, Laphookhieo S, Chang LC.

Bioorg Med Chem Lett. 2017 Aug 15;27(16):3760-3765. doi: 10.1016/j.bmcl.2017.06.073. Epub 2017 Jul 1.

PMID:
28729053
4.

15α-methoxypuupehenol Induces Antitumor Effects In Vitro and In Vivo against Human Glioblastoma and Breast Cancer Models.

Hilliard TS, Miklossy G, Chock C, Yue P, Williams P, Turkson J.

Mol Cancer Ther. 2017 Apr;16(4):601-613. doi: 10.1158/1535-7163.MCT-16-0291. Epub 2017 Jan 9.

5.

Meroterpenoids with Antiproliferative Activity from a Hawaiian-Plant Associated Fungus Peyronellaea coffeae-arabicae FT238.

Li CS, Ren G, Yang BJ, Miklossy G, Turkson J, Fei P, Ding Y, Walker LA, Cao S.

Org Lett. 2016 May 20;18(10):2335-8. doi: 10.1021/acs.orglett.6b00685. Epub 2016 May 2.

PMID:
27135759
6.

Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin α-2 Expression, and Induce Antitumor Effects against Human Glioma.

Miklossy G, Youn UJ, Yue P, Zhang M, Chen CH, Hilliard TS, Paladino D, Li Y, Choi J, Sarkaria JN, Kawakami JK, Wongwiwatthananukit S, Chen Y, Sun D, Chang LC, Turkson J.

J Med Chem. 2015 Oct 8;58(19):7734-48. doi: 10.1021/acs.jmedchem.5b00686. Epub 2015 Sep 17.

7.

A New Metabolite with a Unique 4-Pyranone-γ-Lactam-1,4-Thiazine Moiety from a Hawaiian-Plant Associated Fungus.

Li CS, Ding Y, Yang BJ, Miklossy G, Yin HQ, Walker LA, Turkson J, Cao S.

Org Lett. 2015 Jul 17;17(14):3556-9. doi: 10.1021/acs.orglett.5b01650. Epub 2015 Jun 24.

PMID:
26107089
8.

HRES-1/Rab4 promotes the formation of LC3(+) autophagosomes and the accumulation of mitochondria during autophagy.

Talaber G, Miklossy G, Oaks Z, Liu Y, Tooze SA, Chudakov DM, Banki K, Perl A.

PLoS One. 2014 Jan 3;9(1):e84392. doi: 10.1371/journal.pone.0084392. eCollection 2014.

9.

Bioactive sesquiterpene lactones and other compounds isolated from Vernonia cinerea.

Youn UJ, Miklossy G, Chai X, Wongwiwatthananukit S, Toyama O, Songsak T, Turkson J, Chang LC.

Fitoterapia. 2014 Mar;93:194-200. doi: 10.1016/j.fitote.2013.12.013. Epub 2013 Dec 24.

10.

Therapeutic modulators of STAT signalling for human diseases.

Miklossy G, Hilliard TS, Turkson J.

Nat Rev Drug Discov. 2013 Aug;12(8):611-29. doi: 10.1038/nrd4088. Review.

11.

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.

Caza TN, Fernandez DR, Talaber G, Oaks Z, Haas M, Madaio MP, Lai ZW, Miklossy G, Singh RR, Chudakov DM, Malorni W, Middleton F, Banki K, Perl A.

Ann Rheum Dis. 2014 Oct;73(10):1888-97. doi: 10.1136/annrheumdis-2013-203794. Epub 2013 Jul 29.

12.

N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.

Lai ZW, Hanczko R, Bonilla E, Caza TN, Clair B, Bartos A, Miklossy G, Jimah J, Doherty E, Tily H, Francis L, Garcia R, Dawood M, Yu J, Ramos I, Coman I, Faraone SV, Phillips PE, Perl A.

Arthritis Rheum. 2012 Sep;64(9):2937-46. doi: 10.1002/art.34502.

13.

Cleavage of transaldolase by granzyme B causes the loss of enzymatic activity with retention of antigenicity for multiple sclerosis patients.

Niland B, Miklossy G, Banki K, Biddison WE, Casciola-Rosen L, Rosen A, Martinvalet D, Lieberman J, Perl A.

J Immunol. 2010 Apr 1;184(7):4025-32. doi: 10.4049/jimmunol.0804174. Epub 2010 Mar 1.

14.

Constitutive and UV-B modulated transcription of Nod-like receptors and their functional partners in human corneal epithelial cells.

Benko S, Tozser J, Miklossy G, Varga A, Kadas J, Csutak A, Berta A, Rajnavolgyi E.

Mol Vis. 2008 Aug 29;14:1575-83.

15.

Amino acid preferences of retroviral proteases for amino-terminal positions in a type 1 cleavage site.

Eizert H, Bander P, Bagossi P, Sperka T, Miklóssy G, Boross P, Weber IT, Tözsér J.

J Virol. 2008 Oct;82(20):10111-7. doi: 10.1128/JVI.00418-08. Epub 2008 Aug 13.

16.

Novel macromolecular inhibitors of human immunodeficiency virus-1 protease.

Miklóssy G, Tözsér J, Kádas J, Ishima R, Louis JM, Bagossi P.

Protein Eng Des Sel. 2008 Jul;21(7):453-61. doi: 10.1093/protein/gzn022. Epub 2008 May 13.

17.

Bovine leukemia virus protease: comparison with human T-lymphotropic virus and human immunodeficiency virus proteases.

Sperka T, Miklóssy G, Tie Y, Bagossi P, Zahuczky G, Boross P, Matúz K, Harrison RW, Weber IT, Tözsér J.

J Gen Virol. 2007 Jul;88(Pt 7):2052-63.

PMID:
17554040
18.

Characterization of the murine leukemia virus protease and its comparison with the human immunodeficiency virus type 1 protease.

Fehér A, Boross P, Sperka T, Miklóssy G, Kádas J, Bagossi P, Oroszlan S, Weber IT, Tözsér J.

J Gen Virol. 2006 May;87(Pt 5):1321-30.

PMID:
16603535
19.

Amino acid preferences for a critical substrate binding subsite of retroviral proteases in type 1 cleavage sites.

Bagossi P, Sperka T, Fehér A, Kádas J, Zahuczky G, Miklóssy G, Boross P, Tözsér J.

J Virol. 2005 Apr;79(7):4213-8.

20.

Development of a microtiter plate fluorescent assay for inhibition studies on the HTLV-1 and HIV-1 proteinases.

Bagossi P, Kádas J, Miklóssy G, Boross P, Weber IT, Tözsér J.

J Virol Methods. 2004 Aug;119(2):87-93.

PMID:
15158589
21.

Narrow substrate specificity and sensitivity toward ligand-binding site mutations of human T-cell Leukemia virus type 1 protease.

Kádas J, Weber IT, Bagossi P, Miklóssy G, Boross P, Oroszlan S, Tözsér J.

J Biol Chem. 2004 Jun 25;279(26):27148-57. Epub 2004 Apr 20.

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