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Circulating tumor DNA assessment in patients with diffuse large B-cell lymphoma following CAR T-cell therapy.

Hossain NM, Dahiya S, Le R, Abramian AM, Kong KA, Muffly LS, Miklos DB.

Leuk Lymphoma. 2018 Jul 3:1-4. doi: 10.1080/10428194.2018.1474463. [Epub ahead of print] No abstract available.


Evaluation of advanced oxidation processes for water and wastewater treatment - A critical review.

Miklos DB, Remy C, Jekel M, Linden KG, Drewes JE, Hübner U.

Water Res. 2018 Aug 1;139:118-131. doi: 10.1016/j.watres.2018.03.042. Epub 2018 Mar 22. Review.


UV/H2O2 process stability and pilot-scale validation for trace organic chemical removal from wastewater treatment plant effluents.

Miklos DB, Hartl R, Michel P, Linden KG, Drewes JE, Hübner U.

Water Res. 2018 Jun 1;136:169-179. doi: 10.1016/j.watres.2018.02.044. Epub 2018 Feb 21.


HLA-mismatched unrelated donor transplantation using TLI-ATG conditioning has a low risk of GVHD and potent antitumor activity.

Spinner MA, Fernández-Viña M, Creary LE, Quinn O, Elder L, Arai S, Johnston LJ, Meyer EH, Miklos DB, Muffly LS, Negrin RS, Shizuru JA, Weng WK, Laport GG, Strober S, Lowsky R, Rezvani AR.

Blood Adv. 2017 Jul 25;1(17):1347-1357. doi: 10.1182/bloodadvances.2017007716. eCollection 2017 Jul 25.


Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.

Neelapu SS, Locke FL, Bartlett NL, Lekakis LJ, Miklos DB, Jacobson CA, Braunschweig I, Oluwole OO, Siddiqi T, Lin Y, Timmerman JM, Stiff PJ, Friedberg JW, Flinn IW, Goy A, Hill BT, Smith MR, Deol A, Farooq U, McSweeney P, Munoz J, Avivi I, Castro JE, Westin JR, Chavez JC, Ghobadi A, Komanduri KV, Levy R, Jacobsen ED, Witzig TE, Reagan P, Bot A, Rossi J, Navale L, Jiang Y, Aycock J, Elias M, Chang D, Wiezorek J, Go WY.

N Engl J Med. 2017 Dec 28;377(26):2531-2544. doi: 10.1056/NEJMoa1707447. Epub 2017 Dec 10.


CNS Endothelial Cell Activation Emerges as a Driver of CAR T Cell-Associated Neurotoxicity.

Mackall CL, Miklos DB.

Cancer Discov. 2017 Dec;7(12):1371-1373. doi: 10.1158/2159-8290.CD-17-1084.


Anti-Platelet-Derived Growth Factor Receptor Alpha Chain Antibodies Predict for Response to Nilotinib in Steroid-Refractory or -Dependent Chronic Graft-Versus-Host Disease.

Chen GL, Carpenter PA, Broady R, Gregory TK, Johnston LJ, Storer BE, Beumer JH, Qiu J, Cerda K, Le R, Otani JM, Liu H, Ross MA, Arai S, Flowers MED, McCarthy PL, Miklos DB.

Biol Blood Marrow Transplant. 2018 Feb;24(2):373-380. doi: 10.1016/j.bbmt.2017.10.021. Epub 2017 Oct 16.


Ibrutinib efficacy and tolerability in patients with relapsed chronic lymphocytic leukemia following allogeneic HCT.

Ryan CE, Sahaf B, Logan AC, O'Brien S, Byrd JC, Hillmen P, Brown JR, Dyer MJ, Mato AR, Keating MJ, Jaglowski S, Clow F, Rezvani AR, Styles L, Coutre SE, Miklos DB.

Blood. 2016 Dec 22;128(25):2899-2908. doi: 10.1182/blood-2016-06-715284. Epub 2016 Nov 1.


The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease.

Cooke KR, Luznik L, Sarantopoulos S, Hakim FT, Jagasia M, Fowler DH, van den Brink MRM, Hansen JA, Parkman R, Miklos DB, Martin PJ, Paczesny S, Vogelsang G, Pavletic S, Ritz J, Schultz KR, Blazar BR.

Biol Blood Marrow Transplant. 2017 Feb;23(2):211-234. doi: 10.1016/j.bbmt.2016.09.023. Epub 2016 Oct 3. Review.


Presensitization to HY antigens in female donors prior to transplant is not associated with male recipient post-transplant HY antibody development nor with clinical outcomes.

Nakasone H, Sahaf B, Tian L, Wang T, Haagenson MD, Schoenrock K, Perloff S, Ryan CE, Wu F, Spellman SR, Lee SJ, Ritz J, Miklos DB; Center for International Blood and Marrow Transplantation.

Haematologica. 2016 Jan;101(1):e30-3. doi: 10.3324/haematol.2015.134551. Epub 2015 Oct 22. No abstract available.


SNPs and prognosis of GvHD before HCT: any progress?

Abu Zaid MI, Paczesny S, Miklos DB.

Bone Marrow Transplant. 2016 Feb;51(2):161-2. doi: 10.1038/bmt.2015.240. Epub 2015 Oct 12. No abstract available.


A Randomized Phase II Crossover Study of Imatinib or Rituximab for Cutaneous Sclerosis after Hematopoietic Cell Transplantation.

Arai S, Pidala J, Pusic I, Chai X, Jaglowski S, Khera N, Palmer J, Chen GL, Jagasia MH, Mayer SA, Wood WA, Green M, Hyun TS, Inamoto Y, Storer BE, Miklos DB, Shulman HM, Martin PJ, Sarantopoulos S, Lee SJ, Flowers ME.

Clin Cancer Res. 2016 Jan 15;22(2):319-27. doi: 10.1158/1078-0432.CCR-15-1443. Epub 2015 Sep 16.


Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy.

Nakasone H, Remberger M, Tian L, Brodin P, Sahaf B, Wu F, Mattsson J, Lowsky R, Negrin R, Miklos DB, Meyer E.

Haematologica. 2015 Nov;100(11):1477-85. doi: 10.3324/haematol.2015.125294. Epub 2015 Aug 6.


Allogeneic hematopoietic cell transplantation after failed autologous transplant for lymphoma using TLI and anti-thymocyte globulin conditioning.

Rezvani AR, Kanate AS, Efron B, Chhabra S, Kohrt HE, Shizuru JA, Laport GG, Miklos DB, Benjamin JE, Johnston LJ, Arai S, Weng WK, Negrin RS, Strober S, Lowsky R.

Bone Marrow Transplant. 2015 Oct;50(10):1286-92. doi: 10.1038/bmt.2015.149. Epub 2015 Jul 6.


Allogeneic hematopoietic cell transplant for normal karyotype AML: indirect evidence of selection for adverse molecular profile.

Percival MM, Medeiros BC, Tian L, Robeson S, Laport GG, Johnston LJ, Shizuru JA, Miklos DB, Arai S, Weng WK, Negrin RS, Lowsky R.

Bone Marrow Transplant. 2015 Jul;50(7):1004-1006. doi: 10.1038/bmt.2015.62. Epub 2015 Apr 20. No abstract available.


Red blood cell transfusions are associated with HLA class I but not H-Y alloantibodies in children with sickle cell disease.

Nickel RS, Hendrickson JE, Yee MM, Bray RA, Gebel HM, Kean LS, Miklos DB, Horan JT.

Br J Haematol. 2015 Jul;170(2):247-56. doi: 10.1111/bjh.13424. Epub 2015 Apr 19.


Therapeutic benefits targeting B-cells in chronic graft-versus-host disease.

Nakasone H, Sahaf B, Miklos DB.

Int J Hematol. 2015 May;101(5):438-51. doi: 10.1007/s12185-015-1782-4. Epub 2015 Mar 27. Review.


Allogeneic HY antibodies detected 3 months after female-to-male HCT predict chronic GVHD and nonrelapse mortality in humans.

Nakasone H, Tian L, Sahaf B, Kawase T, Schoenrock K, Perloff S, Ryan CE, Paul J, Popli R, Wu F, Otani JM, Coller J, Warren EH 3rd, Miklos DB.

Blood. 2015 May 14;125(20):3193-201. doi: 10.1182/blood-2014-11-613323. Epub 2015 Mar 12.


ABO mismatch is associated with increased nonrelapse mortality after allogeneic hematopoietic cell transplantation.

Logan AC, Wang Z, Alimoghaddam K, Wong RM, Lai T, Negrin RS, Grumet C, Logan BR, Zhang MJ, Spellman SR, Lee SJ, Miklos DB; Center for International Blood and Marrow Transplantation.

Biol Blood Marrow Transplant. 2015 Apr;21(4):746-54. doi: 10.1016/j.bbmt.2014.12.036. Epub 2015 Jan 5.


A reduced-toxicity regimen is associated with durable engraftment and clinical cure of nonmalignant genetic diseases among children undergoing blood and marrow transplantation with an HLA-matched related donor.

Mahadeo KM, Weinberg KI, Abdel-Azim H, Miklos DB, Killen R, Kohn D, Crooks GM, Shah AJ, Kharbanda S, Agarwal R, Kapoor N.

Biol Blood Marrow Transplant. 2015 Mar;21(3):440-4. doi: 10.1016/j.bbmt.2014.11.005. Epub 2014 Nov 13.


European LeukemiaNet classification intermediate risk-1 cohort is associated with poor outcomes in adults with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation.

Medeiros BC, Tian L, Robenson S, Laport GG, Johnston LJ, Shizuru JA, Miklos DB, Arai S, Benjamin JE, Weng WK, Negrin RS, Lowsky R.

Blood Cancer J. 2014 May 30;4:e216. doi: 10.1038/bcj.2014.35. No abstract available.


Clinical impact of H-Y alloimmunity.

Popli R, Sahaf B, Nakasone H, Lee JY, Miklos DB.

Immunol Res. 2014 May;58(2-3):249-58. doi: 10.1007/s12026-014-8514-3. Review.


Immunoglobulin and T cell receptor gene high-throughput sequencing quantifies minimal residual disease in acute lymphoblastic leukemia and predicts post-transplantation relapse and survival.

Logan AC, Vashi N, Faham M, Carlton V, Kong K, Buño I, Zheng J, Moorhead M, Klinger M, Zhang B, Waqar A, Zehnder JL, Miklos DB.

Biol Blood Marrow Transplant. 2014 Sep;20(9):1307-13. doi: 10.1016/j.bbmt.2014.04.018. Epub 2014 Apr 24.


Total lymphoid irradiation-antithymocyte globulin conditioning and allogeneic transplantation for patients with myelodysplastic syndromes and myeloproliferative neoplasms.

Benjamin J, Chhabra S, Kohrt HE, Lavori P, Laport GG, Arai S, Johnston L, Miklos DB, Shizuru JA, Weng WK, Negrin RS, Lowsky R.

Biol Blood Marrow Transplant. 2014 Jun;20(6):837-43. doi: 10.1016/j.bbmt.2014.02.023. Epub 2014 Mar 7.


A distinct evolution of the T-cell repertoire categorizes treatment refractory gastrointestinal acute graft-versus-host disease.

Meyer EH, Hsu AR, Liliental J, Löhr A, Florek M, Zehnder JL, Strober S, Lavori P, Miklos DB, Johnson DS, Negrin RS.

Blood. 2013 Jun 13;121(24):4955-62. doi: 10.1182/blood-2013-03-489757. Epub 2013 May 7.


Minimal residual disease quantification using consensus primers and high-throughput IGH sequencing predicts post-transplant relapse in chronic lymphocytic leukemia.

Logan AC, Zhang B, Narasimhan B, Carlton V, Zheng J, Moorhead M, Krampf MR, Jones CD, Waqar AN, Faham M, Zehnder JL, Miklos DB.

Leukemia. 2013 Aug;27(8):1659-65. doi: 10.1038/leu.2013.52. Epub 2013 Feb 19.


H-Y antigen-binding B cells develop in male recipients of female hematopoietic cells and associate with chronic graft vs. host disease.

Sahaf B, Yang Y, Arai S, Herzenberg LA, Herzenberg LA, Miklos DB.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3005-10. doi: 10.1073/pnas.1222900110. Epub 2013 Feb 4.


Massive evolution of the immunoglobulin heavy chain locus in children with B precursor acute lymphoblastic leukemia.

Gawad C, Pepin F, Carlton VE, Klinger M, Logan AC, Miklos DB, Faham M, Dahl G, Lacayo N.

Blood. 2012 Nov 22;120(22):4407-17. doi: 10.1182/blood-2012-05-429811. Epub 2012 Aug 28.


Humoral immunity to cytomegalovirus and chronic graft-versus-host disease.

Namboodiri AM, Nietert PJ, Wadia PP, Miklos DB, Pandey JP.

Viral Immunol. 2012 Aug;25(4):338-40. doi: 10.1089/vim.2012.0013. Epub 2012 Jul 17.


Prophylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence.

Arai S, Sahaf B, Narasimhan B, Chen GL, Jones CD, Lowsky R, Shizuru JA, Johnston LJ, Laport GG, Weng WK, Benjamin JE, Schaenman J, Brown J, Ramirez J, Zehnder JL, Negrin RS, Miklos DB.

Blood. 2012 Jun 21;119(25):6145-54. doi: 10.1182/blood-2011-12-395970. Epub 2012 May 4.


High-throughput VDJ sequencing for quantification of minimal residual disease in chronic lymphocytic leukemia and immune reconstitution assessment.

Logan AC, Gao H, Wang C, Sahaf B, Jones CD, Marshall EL, Buño I, Armstrong R, Fire AZ, Weinberg KI, Mindrinos M, Zehnder JL, Boyd SD, Xiao W, Davis RW, Miklos DB.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21194-9. doi: 10.1073/pnas.1118357109. Epub 2011 Dec 12.


A phase 1 study of imatinib for corticosteroid-dependent/refractory chronic graft-versus-host disease: response does not correlate with anti-PDGFRA antibodies.

Chen GL, Arai S, Flowers ME, Otani JM, Qiu J, Cheng EC, McMillan A, Johnston LJ, Shizuru JA, Miklos DB.

Blood. 2011 Oct 13;118(15):4070-8. doi: 10.1182/blood-2011-03-341693. Epub 2011 Aug 9.


Combined CD4 T-cell and antibody response to human minor histocompatibility antigen DBY after allogeneic stem-cell transplantation.

Porcheray F, Miklos DB, Floyd BH, Sarantopoulos S, Bellucci R, Soiffer RJ, Antin JH, Alyea EP, Ritz J, Zorn E.

Transplantation. 2011 Aug 15;92(3):359-65. doi: 10.1097/TP.0b013e3182244cc3.


Tandem chemo-mobilization followed by high-dose melphalan and carmustine with single autologous hematopoietic cell transplantation for multiple myeloma.

Chen AI, Negrin RS, McMillan A, Shizuru JA, Johnston LJ, Lowsky R, Miklos DB, Arai S, Weng WK, Laport GG, Stockerl-Goldstein K.

Bone Marrow Transplant. 2012 Apr;47(4):516-21. doi: 10.1038/bmt.2011.106. Epub 2011 May 23.


B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies.

Winer DA, Winer S, Shen L, Wadia PP, Yantha J, Paltser G, Tsui H, Wu P, Davidson MG, Alonso MN, Leong HX, Glassford A, Caimol M, Kenkel JA, Tedder TF, McLaughlin T, Miklos DB, Dosch HM, Engleman EG.

Nat Med. 2011 May;17(5):610-7. doi: 10.1038/nm.2353. Epub 2011 Apr 17.


Recombinant antigen microarrays for serum/plasma antibody detection.

Wadia PP, Sahaf B, Miklos DB.

Methods Mol Biol. 2011;723:81-104. doi: 10.1007/978-1-61779-043-0_7.


Clonally identical Hodgkin's disease develops after allogeneic hematopoietic cell transplant for CLL.

Tseng D, Jones CD, Anderson M, Warnke R, Zehnder JL, Miklos DB.

Bone Marrow Transplant. 2011 Dec;46(12):1576-8. doi: 10.1038/bmt.2010.340. Epub 2011 Jan 24. No abstract available.


Protein microarrays discover angiotensinogen and PRKRIP1 as novel targets for autoantibodies in chronic renal disease.

Butte AJ, Sigdel TK, Wadia PP, Miklos DB, Sarwal MM.

Mol Cell Proteomics. 2011 Mar;10(3):M110.000497. doi: 10.1074/mcp.M110.000497. Epub 2010 Dec 23.


Complete donor T-cell engraftment 30 days after allogeneic transplantation predicts molecular remission in high-risk chronic lymphocytic leukaemia.

Jones CD, Arai S, Lowsky R, Tyan DB, Zehnder JL, Miklos DB.

Br J Haematol. 2010 Sep;150(5):637-9. doi: 10.1111/j.1365-2141.2010.08252.x. Epub 2010 Jun 7. No abstract available.


Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements.

Boyd SD, Gaëta BA, Jackson KJ, Fire AZ, Marshall EL, Merker JD, Maniar JM, Zhang LN, Sahaf B, Jones CD, Simen BB, Hanczaruk B, Nguyen KD, Nadeau KC, Egholm M, Miklos DB, Zehnder JL, Collins AM.

J Immunol. 2010 Jun 15;184(12):6986-92. doi: 10.4049/jimmunol.1000445. Epub 2010 May 21.


Rituximab in hematopoietic cell transplantation.

Arai S, Miklos DB.

Expert Opin Biol Ther. 2010 Jun;10(6):971-82. doi: 10.1517/14712598.2010.485982. Review.


Phase I/II trial of GN-BVC, a gemcitabine and vinorelbine-containing conditioning regimen for autologous hematopoietic cell transplantation in recurrent and refractory hodgkin lymphoma.

Arai S, Letsinger R, Wong RM, Johnston LJ, Laport GG, Lowsky R, Miklos DB, Shizuru JA, Weng WK, Lavori PW, Blume KG, Negrin RS, Horning SJ.

Biol Blood Marrow Transplant. 2010 Aug;16(8):1145-54. doi: 10.1016/j.bbmt.2010.02.022. Epub 2010 Mar 1.


Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing.

Boyd SD, Marshall EL, Merker JD, Maniar JM, Zhang LN, Sahaf B, Jones CD, Simen BB, Hanczaruk B, Nguyen KD, Nadeau KC, Egholm M, Miklos DB, Zehnder JL, Fire AZ.

Sci Transl Med. 2009 Dec 23;1(12):12ra23.


Antibodies specifically target AML antigen NuSAP1 after allogeneic bone marrow transplantation.

Wadia PP, Coram M, Armstrong RJ, Mindrinos M, Butte AJ, Miklos DB.

Blood. 2010 Mar 11;115(10):2077-87. doi: 10.1182/blood-2009-03-211375. Epub 2010 Jan 6.


Protein microarrays identify antibodies to protein kinase Czeta that are associated with a greater risk of allograft loss in pediatric renal transplant recipients.

Sutherland SM, Li L, Sigdel TK, Wadia PP, Miklos DB, Butte AJ, Sarwal MM.

Kidney Int. 2009 Dec;76(12):1277-83. doi: 10.1038/ki.2009.384. Epub 2009 Oct 7.


TLI and ATG conditioning with low risk of graft-versus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors.

Kohrt HE, Turnbull BB, Heydari K, Shizuru JA, Laport GG, Miklos DB, Johnston LJ, Arai S, Weng WK, Hoppe RT, Lavori PW, Blume KG, Negrin RS, Strober S, Lowsky R.

Blood. 2009 Jul 30;114(5):1099-109. doi: 10.1182/blood-2009-03-211441. Epub 2009 May 7.


Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures.

Li L, Wadia P, Chen R, Kambham N, Naesens M, Sigdel TK, Miklos DB, Sarwal MM, Butte AJ.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4148-53. doi: 10.1073/pnas.0900563106. Epub 2009 Feb 27.


B cells and transplantation: an educational resource.

Small TN, Robinson WH, Miklos DB.

Biol Blood Marrow Transplant. 2009 Jan;15(1 Suppl):104-13. doi: 10.1016/j.bbmt.2008.10.016. Review. No abstract available. Erratum in: Biol Blood Marrow Transplant. 2009 Aug;15(8):1003.


H-Y antibody development associates with acute rejection in female patients with male kidney transplants.

Tan JC, Wadia PP, Coram M, Grumet FC, Kambham N, Miller K, Pereira S, Vayntrub T, Miklos DB.

Transplantation. 2008 Jul 15;86(1):75-81. doi: 10.1097/TP.0b013e31817352b9.


Renal pathology in hematopoietic cell transplantation recipients.

Troxell ML, Pilapil M, Miklos DB, Higgins JP, Kambham N.

Mod Pathol. 2008 Apr;21(4):396-406. doi: 10.1038/modpathol.3801011. Epub 2008 Jan 25.

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