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Items: 13

1.

ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour.

Edris B, Espinosa I, Mühlenberg T, Mikels A, Lee CH, Steigen SE, Zhu S, Montgomery KD, Lazar AJ, Lev D, Fletcher JA, Beck AH, West RB, Nusse R, van de Rijn M.

J Pathol. 2012 Jun;227(2):223-33. doi: 10.1002/path.3986. Epub 2012 Feb 17.

2.

Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment.

Barry-Hamilton V, Spangler R, Marshall D, McCauley S, Rodriguez HM, Oyasu M, Mikels A, Vaysberg M, Ghermazien H, Wai C, Garcia CA, Velayo AC, Jorgensen B, Biermann D, Tsai D, Green J, Zaffryar-Eilot S, Holzer A, Ogg S, Thai D, Neufeld G, Van Vlasselaer P, Smith V.

Nat Med. 2010 Sep;16(9):1009-17. doi: 10.1038/nm.2208. Epub 2010 Sep 5.

PMID:
20818376
3.

Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor.

Rodriguez HM, Vaysberg M, Mikels A, McCauley S, Velayo AC, Garcia C, Smith V.

J Biol Chem. 2010 Jul 2;285(27):20964-74. doi: 10.1074/jbc.M109.094136. Epub 2010 May 3.

4.

Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responses.

Carlson ME, Conboy MJ, Hsu M, Barchas L, Jeong J, Agrawal A, Mikels AJ, Agrawal S, Schaffer DV, Conboy IM.

Aging Cell. 2009 Dec;8(6):676-89. doi: 10.1111/j.1474-9726.2009.00517.x. Epub 2009 Sep 2.

5.

Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling.

Mikels A, Minami Y, Nusse R.

J Biol Chem. 2009 Oct 30;284(44):30167-76. doi: 10.1074/jbc.M109.041715. Epub 2009 Aug 31.

6.

Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma.

Wright TM, Brannon AR, Gordan JD, Mikels AJ, Mitchell C, Chen S, Espinosa I, van de Rijn M, Pruthi R, Wallen E, Edwards L, Nusse R, Rathmell WK.

Oncogene. 2009 Jul 9;28(27):2513-23. doi: 10.1038/onc.2009.116. Epub 2009 May 18.

7.

Wnt signaling during Caenorhabditis elegans embryonic development.

Marston DJ, Roh M, Mikels AJ, Nusse R, Goldstein B.

Methods Mol Biol. 2008;469:103-11. doi: 10.1007/978-1-60327-469-9.

8.

Alternative wnt signaling is initiated by distinct receptors.

van Amerongen R, Mikels A, Nusse R.

Sci Signal. 2008 Sep 2;1(35):re9. doi: 10.1126/scisignal.135re9. Review.

PMID:
18765832
9.

Chick pulmonary Wnt5a directs airway and vascular tubulogenesis.

Loscertales M, Mikels AJ, Hu JK, Donahoe PK, Roberts DJ.

Development. 2008 Apr;135(7):1365-76. doi: 10.1242/dev.010504. Epub 2008 Feb 27.

10.

A dermal HOX transcriptional program regulates site-specific epidermal fate.

Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY.

Genes Dev. 2008 Feb 1;22(3):303-7. doi: 10.1101/gad.1610508.

11.

Wnts as ligands: processing, secretion and reception.

Mikels AJ, Nusse R.

Oncogene. 2006 Dec 4;25(57):7461-8. Review.

PMID:
17143290
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