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Items: 34


First report of hare treponematosis seroprevalence of European brown hares (Lepus europaeus) in the Czech Republic: seroprevalence negatively correlates with altitude of sampling areas.

Nováková M, Najt D, Mikalová L, Kostková M, Vrbová E, Strouhal M, Posautz A, Knauf S, Šmajs D.

BMC Vet Res. 2019 Oct 18;15(1):350. doi: 10.1186/s12917-019-2086-3.


Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens.

Grillová L, Oppelt J, Mikalová L, Nováková M, Giacani L, Niesnerová A, Noda AA, Mechaly AE, Pospíšilová P, Čejková D, Grange PA, Dupin N, Strnadel R, Chen M, Denham I, Arora N, Picardeau M, Weston C, Forsyth RA, Šmajs D.

Front Microbiol. 2019 Jul 31;10:1691. doi: 10.3389/fmicb.2019.01691. eCollection 2019.


Identification of positively selected genes in human pathogenic treponemes: Syphilis-, yaws-, and bejel-causing strains differ in sets of genes showing adaptive evolution.

Maděránková D, Mikalová L, Strouhal M, Vadják Š, Kuklová I, Pospíšilová P, Krbková L, Koščová P, Provazník I, Šmajs D.

PLoS Negl Trop Dis. 2019 Jun 19;13(6):e0007463. doi: 10.1371/journal.pntd.0007463. eCollection 2019 Jun.


MLST typing of Treponema pallidum subsp. pallidum in the Czech Republic during 2004-2017: Clinical isolates belonged to 25 allelic profiles and harbored 8 novel allelic variants.

Vrbová E, Grillová L, Mikalová L, Pospíšilová P, Strnadel R, Dastychová E, Kojanová M, Kreidlová M, Vaňousová D, Rob F, Procházka P, Krchňáková A, Vašků V, Woznicová V, Dvořáková Heroldová M, Kuklová I, Zákoucká H, Šmajs D.

PLoS One. 2019 May 31;14(5):e0217611. doi: 10.1371/journal.pone.0217611. eCollection 2019.


Complete genome sequences of two strains of Treponema pallidum subsp. pertenue from Indonesia: Modular structure of several treponemal genes.

Strouhal M, Mikalová L, Haviernik J, Knauf S, Bruisten S, Noordhoek GT, Oppelt J, Čejková D, Šmajs D.

PLoS Negl Trop Dis. 2018 Oct 10;12(10):e0006867. doi: 10.1371/journal.pntd.0006867. eCollection 2018 Oct.


Nonhuman primates across sub-Saharan Africa are infected with the yaws bacterium Treponema pallidum subsp. pertenue.

Knauf S, Gogarten JF, Schuenemann VJ, De Nys HM, Düx A, Strouhal M, Mikalová L, Bos KI, Armstrong R, Batamuzi EK, Chuma IS, Davoust B, Diatta G, Fyumagwa RD, Kazwala RR, Keyyu JD, Lejora IAV, Levasseur A, Liu H, Mayhew MA, Mediannikov O, Raoult D, Wittig RM, Roos C, Leendertz FH, Šmajs D, Nieselt K, Krause J, Calvignac-Spencer S.

Emerg Microbes Infect. 2018 Sep 19;7(1):157. doi: 10.1038/s41426-018-0156-4. No abstract available.


Sequencing of Treponema pallidum subsp. pallidum from isolate UZ1974 using Anti-Treponemal Antibodies Enrichment: First complete whole genome sequence obtained directly from human clinical material.

Grillová L, Giacani L, Mikalová L, Strouhal M, Strnadel R, Marra C, Centurion-Lara A, Poveda L, Russo G, Čejková D, Vašků V, Oppelt J, Šmajs D.

PLoS One. 2018 Aug 21;13(8):e0202619. doi: 10.1371/journal.pone.0202619. eCollection 2018.


Molecular characterization of Treponema pallidum subsp. pallidum in Switzerland and France with a new multilocus sequence typing scheme.

Grillová L, Bawa T, Mikalová L, Gayet-Ageron A, Nieselt K, Strouhal M, Sednaoui P, Ferry T, Cavassini M, Lautenschlager S, Dutly F, Pla-Díaz M, Krützen M, González-Candelas F, Bagheri HC, Šmajs D, Arora N, Bosshard PP.

PLoS One. 2018 Jul 30;13(7):e0200773. doi: 10.1371/journal.pone.0200773. eCollection 2018.


Multi-locus sequence typing of Treponema pallidum subsp. pallidum present in clinical samples from France: Infecting treponemes are genetically diverse and belong to 18 allelic profiles.

Pospíšilová P, Grange PA, Grillová L, Mikalová L, Martinet P, Janier M, Vermersch A, Benhaddou N, Del Giudice P, Alcaraz I, Truchetet F, Dupin N, Šmajs D.

PLoS One. 2018 Jul 19;13(7):e0201068. doi: 10.1371/journal.pone.0201068. eCollection 2018.


Low-dose versus standard-dose azithromycin for treatment of yaws.

Mikalová L, Šmajs D.

Lancet Glob Health. 2018 Apr;6(4):e357-e358. doi: 10.1016/S2214-109X(18)30067-6. Epub 2018 Feb 16. No abstract available.


Reanalysis of Chinese Treponema pallidum samples: all Chinese samples cluster with SS14-like group of syphilis-causing treponemes.

Strouhal M, Oppelt J, Mikalová L, Arora N, Nieselt K, González-Candelas F, Šmajs D.

BMC Res Notes. 2018 Jan 11;11(1):16. doi: 10.1186/s13104-017-3106-7.


Complete genome sequences of two strains of Treponema pallidum subsp. pertenue from Ghana, Africa: Identical genome sequences in samples isolated more than 7 years apart.

Strouhal M, Mikalová L, Havlíčková P, Tenti P, Čejková D, Rychlík I, Bruisten S, Šmajs D.

PLoS Negl Trop Dis. 2017 Sep 8;11(9):e0005894. doi: 10.1371/journal.pntd.0005894. eCollection 2017 Sep.


Molecular Typing of Syphilis-Causing Strains Among Human Immunodeficiency Virus-Positive Patients in Antwerp, Belgium.

Mikalová L, Grillová L, Osbak K, Strouhal M, Kenyon C, Crucitti T, Šmajs D.

Sex Transm Dis. 2017 Jun;44(6):376-379. doi: 10.1097/OLQ.0000000000000600.


Complete Genome Sequence of Bacteriophage SEN8, a Temperate Phage Isolated from Salmonella enterica subsp. salamae.

Bosák J, Mikalová L, Čejková D, Šmarda J, Šmajs D.

Genome Announc. 2017 May 11;5(19). pii: e00239-17. doi: 10.1128/genomeA.00239-17.


Human Treponema pallidum 11q/j isolate belongs to subsp. endemicum but contains two loci with a sequence in TP0548 and TP0488 similar to subsp. pertenue and subsp. pallidum, respectively.

Mikalová L, Strouhal M, Oppelt J, Grange PA, Janier M, Benhaddou N, Dupin N, Šmajs D.

PLoS Negl Trop Dis. 2017 Mar 6;11(3):e0005434. doi: 10.1371/journal.pntd.0005434. eCollection 2017 Mar.


Molecular typing of Treponema pallidum isolates from Buenos Aires, Argentina: Frequent Nichols-like isolates and low levels of macrolide resistance.

Gallo Vaulet L, Grillová L, Mikalová L, Casco R, Rodríguez Fermepin M, Pando MA, Šmajs D.

PLoS One. 2017 Feb 24;12(2):e0172905. doi: 10.1371/journal.pone.0172905. eCollection 2017.


Novel Temperate Phages of Salmonella enterica subsp. salamae and subsp. diarizonae and Their Activity against Pathogenic S. enterica subsp. enterica Isolates.

Mikalová L, Bosák J, Hříbková H, Dědičová D, Benada O, Šmarda J, Šmajs D.

PLoS One. 2017 Jan 24;12(1):e0170734. doi: 10.1371/journal.pone.0170734. eCollection 2017.


Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster.

Arora N, Schuenemann VJ, Jäger G, Peltzer A, Seitz A, Herbig A, Strouhal M, Grillová L, Sánchez-Busó L, Kühnert D, Bos KI, Davis LR, Mikalová L, Bruisten S, Komericki P, French P, Grant PR, Pando MA, Vaulet LG, Fermepin MR, Martinez A, Centurion Lara A, Giacani L, Norris SJ, Šmajs D, Bosshard PP, González-Candelas F, Nieselt K, Krause J, Bagheri HC.

Nat Microbiol. 2016 Dec 5;2:16245. doi: 10.1038/nmicrobiol.2016.245.


Treponema pallidum 11qj Subtype May Correspond to a Treponema pallidum Subsp. Endemicum Strain.

Grange PA, Mikalová L, Gaudin C, Strouhal M, Janier M, Benhaddou N, Šmajs D, Dupin N.

Sex Transm Dis. 2016 Aug;43(8):517-8. doi: 10.1097/OLQ.0000000000000474. No abstract available.


[Macrolide resistance in Treponema pallidum subsp. pallidum in the Czech Republic and in other countries].

Grillová L, Mikalová L, Zákoucká H, Židlická J, Šmajs D.

Epidemiol Mikrobiol Imunol. 2015 Mar;64(1):4-10. Czech.


The 2 simultaneously published "k" sequence variants of tp0548 locus of Treponema pallidum ssp. pallidum isolates differ: the one published later has to be renamed as "l".

Grillová L, Strouhal M, Mikalová L, Šmajs D.

Sex Transm Dis. 2015 Jan;42(1):53. doi: 10.1097/OLQ.0000000000000220. No abstract available.


The molecular typing data of recently identified subtype 11q/j of Treponema pallidum subsp. pallidum suggest imported case of yaws.

Mikalová L, Strouhal M, Grillová L, Smajs D.

Sex Transm Dis. 2014 Sep;41(9):552-3. doi: 10.1097/OLQ.0000000000000165. No abstract available.


Molecular typing of Treponema pallidum in the Czech Republic during 2011 to 2013: increased prevalence of identified genotypes and of isolates with macrolide resistance.

Grillová L, Pĕtrošová H, Mikalová L, Strnadel R, Dastychová E, Kuklová I, Kojanová M, Kreidlová M, Vaňousová D, Hercogová J, Procházka P, Zákoucká H, Krchňáková A, Vašků V, Šmajs D.

J Clin Microbiol. 2014 Oct;52(10):3693-700. doi: 10.1128/JCM.01292-14. Epub 2014 Aug 6.


Syphilis-causing strains belong to separate SS14-like or Nichols-like groups as defined by multilocus analysis of 19 Treponema pallidum strains.

Nechvátal L, Pětrošová H, Grillová L, Pospíšilová P, Mikalová L, Strnadel R, Kuklová I, Kojanová M, Kreidlová M, Vaňousová D, Procházka P, Zákoucká H, Krchňáková A, Smajs D.

Int J Med Microbiol. 2014 Jul;304(5-6):645-53. doi: 10.1016/j.ijmm.2014.04.007. Epub 2014 Apr 26.


Bacteriocin-encoding genes and ExPEC virulence determinants are associated in human fecal Escherichia coli strains.

Micenková L, Štaudová B, Bosák J, Mikalová L, Littnerová S, Vrba M, Ševčíková A, Woznicová V, Šmajs D.

BMC Microbiol. 2014 Apr 28;14:109. doi: 10.1186/1471-2180-14-109.


Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters.

Pětrošová H, Pospíšilová P, Strouhal M, Čejková D, Zobaníková M, Mikalová L, Sodergren E, Weinstock GM, Šmajs D.

PLoS One. 2013 Sep 10;8(9):e74319. doi: 10.1371/journal.pone.0074319. eCollection 2013.


Comparison of CDC and sequence-based molecular typing of syphilis treponemes: tpr and arp loci are variable in multiple samples from the same patient.

Mikalová L, Pospíšilová P, Woznicová V, Kuklová I, Zákoucká H, Smajs D.

BMC Microbiol. 2013 Jul 30;13:178. doi: 10.1186/1471-2180-13-178.


Whole genome sequence of the Treponema Fribourg-Blanc: unspecified simian isolate is highly similar to the yaws subspecies.

Zobaníková M, Strouhal M, Mikalová L, Cejková D, Ambrožová L, Pospíšilová P, Fulton LL, Chen L, Sodergren E, Weinstock GM, Smajs D.

PLoS Negl Trop Dis. 2013 Apr 18;7(4):e2172. doi: 10.1371/journal.pntd.0002172. Print 2013.


Is there a difference between hare syphilis and rabbit syphilis? Cross infection experiments between rabbits and hares.

Lumeij JT, Mikalová L, Smajs D.

Vet Microbiol. 2013 May 31;164(1-2):190-4. doi: 10.1016/j.vetmic.2013.02.001. Epub 2013 Feb 11.


Structure of rrn operons in pathogenic non-cultivable treponemes: sequence but not genomic position of intergenic spacers correlates with classification of Treponema pallidum and Treponema paraluiscuniculi strains.

Cejková D, Zobaníková M, Pospísilová P, Strouhal M, Mikalová L, Weinstock GM, Smajs D.

J Med Microbiol. 2013 Feb;62(Pt 2):196-207. doi: 10.1099/jmm.0.050658-0. Epub 2012 Oct 18.


Whole genome sequence of Treponema pallidum ssp. pallidum, strain Mexico A, suggests recombination between yaws and syphilis strains.

Pětrošová H, Zobaníková M, Čejková D, Mikalová L, Pospíšilová P, Strouhal M, Chen L, Qin X, Muzny DM, Weinstock GM, Šmajs D.

PLoS Negl Trop Dis. 2012;6(9):e1832. doi: 10.1371/journal.pntd.0001832. Epub 2012 Sep 20.


Sequencing-based molecular typing of treponema pallidum strains in the Czech Republic: all identified genotypes are related to the sequence of the SS14 strain.

Flasarová M, Pospíšilová P, Mikalová L, Vališová Z, Dastychová E, Strnadel R, Kuklová I, Woznicová V, Zákoucká H, Šmajs D.

Acta Derm Venereol. 2012 Nov;92(6):669-74. doi: 10.2340/00015555-1335.


Whole genome sequences of three Treponema pallidum ssp. pertenue strains: yaws and syphilis treponemes differ in less than 0.2% of the genome sequence.

Cejková D, Zobaníková M, Chen L, Pospíšilová P, Strouhal M, Qin X, Mikalová L, Norris SJ, Muzny DM, Gibbs RA, Fulton LL, Sodergren E, Weinstock GM, Smajs D.

PLoS Negl Trop Dis. 2012 Jan;6(1):e1471. doi: 10.1371/journal.pntd.0001471. Epub 2012 Jan 24.


Genome analysis of Treponema pallidum subsp. pallidum and subsp. pertenue strains: most of the genetic differences are localized in six regions.

Mikalová L, Strouhal M, Čejková D, Zobaníková M, Pospíšilová P, Norris SJ, Sodergren E, Weinstock GM, Šmajs D.

PLoS One. 2010 Dec 29;5(12):e15713. doi: 10.1371/journal.pone.0015713.

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