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Items: 33


Sensitivity of a ribavirin resistant mutant of hepatitis C virus to other antiviral drugs.

Mihalik KB, Feigelstock DA.

PLoS One. 2013 Sep 5;8(9):e74027. doi: 10.1371/journal.pone.0074027. eCollection 2013.


Selection of hepatitis C virus resistant to ribavirin.

Feigelstock DA, Mihalik KB, Feinstone SM.

Virol J. 2011 Aug 15;8:402. doi: 10.1186/1743-422X-8-402.


Delayed induction, not impaired recruitment, of specific CD8⁺ T cells causes the late onset of acute hepatitis C.

Shin EC, Park SH, Demino M, Nascimbeni M, Mihalik K, Major M, Veerapu NS, Heller T, Feinstone SM, Rice CM, Rehermann B.

Gastroenterology. 2011 Aug;141(2):686-95, 695.e1. doi: 10.1053/j.gastro.2011.05.006. Epub 2011 May 18.


Persistent growth of a human plasma-derived hepatitis C virus genotype 1b isolate in cell culture.

Silberstein E, Mihalik K, Ulitzky L, Plant EP, Puig M, Gagneten S, Yu MY, Kaushik-Basu N, Feinstone SM, Taylor DR.

PLoS Pathog. 2010 May 20;6(5):e1000910. doi: 10.1371/journal.ppat.1000910.


Hepatitis C virus with a naturally occurring single amino-acid substitution in the E2 envelope protein escapes neutralization by naturally-induced and vaccine-induced antibodies.

Duan H, Struble E, Zhong L, Mihalik K, Major M, Zhang P, Feinstone S, Feigelstock D.

Vaccine. 2010 Jun 7;28(25):4138-44. doi: 10.1016/j.vaccine.2010.04.024. Epub 2010 Apr 28.


Increased susceptibility of Huh7 cells to HCV replication does not require mutations in RIG-I.

Feigelstock DA, Mihalik KB, Kaplan G, Feinstone SM.

Virol J. 2010 Feb 19;7:44. doi: 10.1186/1743-422X-7-44.


Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity.

Zhang P, Zhong L, Struble EB, Watanabe H, Kachko A, Mihalik K, Virata-Theimer ML, Alter HJ, Feinstone S, Major M.

Proc Natl Acad Sci U S A. 2009 May 5;106(18):7537-41. doi: 10.1073/pnas.0902749106. Epub 2009 Apr 20.


HFMA roundtable. Are you optimizing your contract performance data?

Daly S, Gibbons K, Livingston D, Mihalik K, Rodriguez D; Concuity.

Healthc Financ Manage. 2008 Nov;62(11):4 p after 30. No abstract available.


Dietary phytochemicals as quorum sensing inhibitors.

Vattem DA, Mihalik K, Crixell SH, McLean RJ.

Fitoterapia. 2007 Jun;78(4):302-10. Epub 2007 Apr 11.


Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasma.

Zhang P, Wu CG, Mihalik K, Virata-Theimer ML, Yu MY, Alter HJ, Feinstone SM.

Proc Natl Acad Sci U S A. 2007 May 15;104(20):8449-54. Epub 2007 May 9.


Evidence for a functional RNA element in the hepatitis C virus core gene.

McMullan LK, Grakoui A, Evans MJ, Mihalik K, Puig M, Branch AD, Feinstone SM, Rice CM.

Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2879-84. Epub 2007 Feb 13.


CD4+ immune escape and subsequent T-cell failure following chimpanzee immunization against hepatitis C virus.

Puig M, Mihalik K, Tilton JC, Williams O, Merchlinsky M, Connors M, Feinstone SM, Major ME.

Hepatology. 2006 Sep;44(3):736-45.


Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C.

Manigold T, Shin EC, Mizukoshi E, Mihalik K, Murthy KK, Rice CM, Piccirillo CA, Rehermann B.

Blood. 2006 Jun 1;107(11):4424-32. Epub 2006 Feb 14.


New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1.

Taylor DR, Puig M, Darnell ME, Mihalik K, Feinstone SM.

J Virol. 2005 May;79(10):6291-8.


Mathematical modeling of primary hepatitis C infection: noncytolytic clearance and early blockage of virion production.

Dahari H, Major M, Zhang X, Mihalik K, Rice CM, Perelson AS, Feinstone SM, Neumann AU.

Gastroenterology. 2005 Apr;128(4):1056-66.


Hepatitis C virus kinetics and host responses associated with disease and outcome of infection in chimpanzees.

Major ME, Dahari H, Mihalik K, Puig M, Rice CM, Neumann AU, Feinstone SM.

Hepatology. 2004 Jun;39(6):1709-20.


Kinetics of CD4+ and CD8+ memory T-cell responses during hepatitis C virus rechallenge of previously recovered chimpanzees.

Nascimbeni M, Mizukoshi E, Bosmann M, Major ME, Mihalik K, Rice CM, Feinstone SM, Rehermann B.

J Virol. 2003 Apr;77(8):4781-93.


Sensitivity and reproducibility of HCV quantitation in chimpanzee sera using TaqMan real-time PCR assay.

Puig M, Mihalik K, Yu MY, Feinstone SM, Major ME.

J Virol Methods. 2002 Sep;105(2):253-63.


Previously infected and recovered chimpanzees exhibit rapid responses that control hepatitis C virus replication upon rechallenge.

Major ME, Mihalik K, Puig M, Rehermann B, Nascimbeni M, Rice CM, Feinstone SM.

J Virol. 2002 Jul;76(13):6586-95.


Molecular and immunological significance of chimpanzee major histocompatibility complex haplotypes for hepatitis C virus immune response and vaccination studies.

Mizukoshi E, Nascimbeni M, Blaustein JB, Mihalik K, Rice CM, Liang TJ, Feinstone SM, Rehermann B.

J Virol. 2002 Jun;76(12):6093-103.


Long-term follow-up of chimpanzees inoculated with the first infectious clone for hepatitis C virus.

Major ME, Mihalik K, Fernandez J, Seidman J, Kleiner D, Kolykhalov AA, Rice CM, Feinstone SM.

J Virol. 1999 Apr;73(4):3317-25.


Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA.

Kolykhalov AA, Agapov EV, Blight KJ, Mihalik K, Feinstone SM, Rice CM.

Science. 1997 Jul 25;277(5325):570-4.


Transmission of nonfermenting gram-negative bacilli by multiple-dose inhalers.

Mihalik K, Demko G.

J Clin Microbiol. 1994 Nov;32(11):2884. No abstract available.


Hepatitis C virus replication during acute infection in the chimpanzee.

Shindo M, Di Bisceglie AM, Biswas R, Mihalik K, Feinstone SM.

J Infect Dis. 1992 Aug;166(2):424-7.


Induction of cytotoxic T cells to a cross-reactive epitope in the hepatitis C virus nonstructural RNA polymerase-like protein.

Shirai M, Akatsuka T, Pendleton CD, Houghten R, Wychowski C, Mihalik K, Feinstone S, Berzofsky JA.

J Virol. 1992 Jul;66(7):4098-106.


Studies of prototype live hepatitis A virus vaccines in primate models.

Karron RA, Daemer R, Ticehurst J, D'Hondt E, Popper H, Mihalik K, Phillips J, Feinstone S, Purcell RH.

J Infect Dis. 1988 Feb;157(2):338-45.


An epidemic of hepatitis A in an institution for young children.

Tassopoulos NC, Roumeliotou-Karayannis A, Sakka M, Ticehurst J, Mihalik K, Stephanou T, Purcell RH, Papaevangelou G.

Am J Epidemiol. 1987 Feb;125(2):302-7.


Inactivation of hepatitis B virus and non-A, non-B hepatitis by chloroform.

Feinstone SM, Mihalik KB, Kamimura T, Alter HJ, London WT, Purcell RH.

Infect Immun. 1983 Aug;41(2):816-21.


Animal model of human disease. Chimpanzee carriers of hepatitis B virus. Chimpanzee hepatitis B carriers.

Thung SN, Gerber MA, Purcell RH, London WT, Mihalik KB, Popper H.

Am J Pathol. 1981 Dec;105(3):328-32. No abstract available.


Colposcopic examination of the cervix of cebus monkeys.

Tunca J, Palmer A, Nahmias A, Mihalik K, Naib Z, London W, Sever J.

Obstet Gynecol. 1978 Nov;52(5):634-9.


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