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Items: 18


PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers.

Gentric G, Kieffer Y, Mieulet V, Goundiam O, Bonneau C, Nemati F, Hurbain I, Raposo G, Popova T, Stern MH, Lallemand-Breitenbach V, Müller S, Cañeque T, Rodriguez R, Vincent-Salomon A, de Thé H, Rossignol R, Mechta-Grigoriou F.

Cell Metab. 2019 Jan 8;29(1):156-173.e10. doi: 10.1016/j.cmet.2018.09.002. Epub 2018 Sep 20.


miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers.

Givel AM, Kieffer Y, Scholer-Dahirel A, Sirven P, Cardon M, Pelon F, Magagna I, Gentric G, Costa A, Bonneau C, Mieulet V, Vincent-Salomon A, Mechta-Grigoriou F.

Nat Commun. 2018 Mar 13;9(1):1056. doi: 10.1038/s41467-018-03348-z.


Heterogeneity in Cancer Metabolism: New Concepts in an Old Field.

Gentric G, Mieulet V, Mechta-Grigoriou F.

Antioxid Redox Signal. 2017 Mar 20;26(9):462-485. doi: 10.1089/ars.2016.6750. Epub 2016 Jul 13. Review.


Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients.

Gruosso T, Mieulet V, Cardon M, Bourachot B, Kieffer Y, Devun F, Dubois T, Dutreix M, Vincent-Salomon A, Miller KM, Mechta-Grigoriou F.

EMBO Mol Med. 2016 May 2;8(5):527-49. doi: 10.15252/emmm.201505891. Print 2016 May.


MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas.

Gruosso T, Garnier C, Abelanet S, Kieffer Y, Lemesre V, Bellanger D, Bieche I, Marangoni E, Sastre-Garau X, Mieulet V, Mechta-Grigoriou F.

Nat Commun. 2015 Oct 12;6:8583. doi: 10.1038/ncomms9583.


Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program.

Chauvin C, Koka V, Nouschi A, Mieulet V, Hoareau-Aveilla C, Dreazen A, Cagnard N, Carpentier W, Kiss T, Meyuhas O, Pende M.

Oncogene. 2014 Jan 23;33(4):474-83. doi: 10.1038/onc.2012.606. Epub 2013 Jan 14.


[Arginine and innate immune response].

Mieulet V, Lamb RF.

Med Sci (Paris). 2011 May;27(5):461-3. doi: 10.1051/medsci/2011275005. Epub 2011 May 25. French. No abstract available.


TPL-2-mediated activation of MAPK downstream of TLR4 signaling is coupled to arginine availability.

Mieulet V, Yan L, Choisy C, Sully K, Procter J, Kouroumalis A, Krywawych S, Pende M, Ley SC, Moinard C, Lamb RF.

Sci Signal. 2010 Aug 17;3(135):ra61. doi: 10.1126/scisignal.2000934.


Tuberous sclerosis complex: linking cancer to metabolism.

Mieulet V, Lamb RF.

Trends Mol Med. 2010 Jul;16(7):329-35. doi: 10.1016/j.molmed.2010.05.001. Epub 2010 Jun 3. Review.


Nutrient regulation of mTORC1 and cell growth.

Yan L, Mieulet V, Lamb RF.

Cell Cycle. 2010 Jul 1;9(13):2473-4. No abstract available.


PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR.

Yan L, Mieulet V, Burgess D, Findlay GM, Sully K, Procter J, Goris J, Janssens V, Morrice NA, Lamb RF.

Mol Cell. 2010 Mar 12;37(5):633-42. doi: 10.1016/j.molcel.2010.01.031.


mTORC2 is the hydrophobic motif kinase for SGK1.

Yan L, Mieulet V, Lamb RF.

Biochem J. 2008 Dec 15;416(3):e19-21. doi: 10.1042/BJ20082202.


Shooting the messenger: CULLIN' insulin signaling with Fbw8.

Mieulet V, Lamb RF.

Dev Cell. 2008 Jun;14(6):816-7. doi: 10.1016/j.devcel.2008.05.010.


S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover.

Mieulet V, Roceri M, Espeillac C, Sotiropoulos A, Ohanna M, Oorschot V, Klumperman J, Sandri M, Pende M.

Am J Physiol Cell Physiol. 2007 Aug;293(2):C712-22. Epub 2007 May 9.


A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.

Findlay GM, Yan L, Procter J, Mieulet V, Lamb RF.

Biochem J. 2007 Apr 1;403(1):13-20.


The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.

Shahbazian D, Roux PP, Mieulet V, Cohen MS, Raught B, Taunton J, Hershey JW, Blenis J, Pende M, Sonenberg N.

EMBO J. 2006 Jun 21;25(12):2781-91. Epub 2006 Jun 8.


S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway.

Pende M, Um SH, Mieulet V, Sticker M, Goss VL, Mestan J, Mueller M, Fumagalli S, Kozma SC, Thomas G.

Mol Cell Biol. 2004 Apr;24(8):3112-24.


Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression.

Guillet-Deniau I, Mieulet V, Le Lay S, Achouri Y, Carré D, Girard J, Foufelle F, Ferré P.

Diabetes. 2002 Jun;51(6):1722-8.

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