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Items: 1 to 50 of 63

1.

Modulation of proinflammatory activity by the engineered cationic antimicrobial peptide WLBU-2.

Paranjape SM, Lauer TW, Montelaro RC, Mietzner TA, Vij N.

F1000Res. 2013 Feb 8;2:36. doi: 10.12688/f1000research.2-36.v1. eCollection 2013.

2.

Rational design of engineered cationic antimicrobial peptides consisting exclusively of arginine and tryptophan, and their activity against multidrug-resistant pathogens.

Deslouches B, Steckbeck JD, Craigo JK, Doi Y, Mietzner TA, Montelaro RC.

Antimicrob Agents Chemother. 2013 Jun;57(6):2511-21. doi: 10.1128/AAC.02218-12. Epub 2013 Mar 18.

3.

FbpA--a bacterial transferrin with more to offer.

Parker Siburt CJ, Mietzner TA, Crumbliss AL.

Biochim Biophys Acta. 2012 Mar;1820(3):379-92. doi: 10.1016/j.bbagen.2011.09.001. Epub 2011 Sep 10. Review.

PMID:
21933698
4.

Role of citrate and phosphate anions in the mechanism of iron(III) sequestration by ferric binding protein: kinetic studies of the formation of the holoprotein of wild-type FbpA and its engineered mutants.

Weaver KD, Gabricević M, Anderson DS, Adhikari P, Mietzner TA, Crumbliss AL.

Biochemistry. 2010 Jul 27;49(29):6021-32. doi: 10.1021/bi902231c.

5.

Hijacking transferrin bound iron: protein-receptor interactions involved in iron transport in N. gonorrhoeae.

Siburt CJ, Roulhac PL, Weaver KD, Noto JM, Mietzner TA, Cornelissen CN, Fitzgerald MC, Crumbliss AL.

Metallomics. 2009;1(3):249-55. doi: 10.1039/b902860a.

6.

Evaluation of WLBU2 peptide and 3-O-octyl-sn-glycerol lipid as active ingredients for a topical microbicide formulation targeting Chlamydia trachomatis.

Skinner MC, Kiselev AO, Isaacs CE, Mietzner TA, Montelaro RC, Lampe MF.

Antimicrob Agents Chemother. 2010 Feb;54(2):627-36. doi: 10.1128/AAC.00635-09. Epub 2009 Dec 14.

7.

Kinetics and mechanism of exogenous anion exchange in FeFbpA-NTA: significance of periplasmic anion lability and anion binding activity of ferric binding protein A.

Heymann JJ, Gabricević M, Mietzner TA, Crumbliss AL.

J Biol Inorg Chem. 2010 Feb;15(2):237-48. doi: 10.1007/s00775-009-0589-2. Epub 2009 Oct 8.

PMID:
19813031
8.

Lipocalin 2 is required for pulmonary host defense against Klebsiella infection.

Chan YR, Liu JS, Pociask DA, Zheng M, Mietzner TA, Berger T, Mak TW, Clifton MC, Strong RK, Ray P, Kolls JK.

J Immunol. 2009 Apr 15;182(8):4947-56. doi: 10.4049/jimmunol.0803282.

9.

Ga3+ as a mechanistic probe in Fe3+ transport: characterization of Ga3+ interaction with FbpA.

Weaver KD, Heymann JJ, Mehta A, Roulhac PL, Anderson DS, Nowalk AJ, Adhikari P, Mietzner TA, Fitzgerald MC, Crumbliss AL.

J Biol Inorg Chem. 2008 Aug;13(6):887-98. doi: 10.1007/s00775-008-0376-5. Epub 2008 May 7.

PMID:
18461372
10.

Ex vivo analysis of synergistic anion binding to FbpA in Gram-negative bacteria.

Roulhac PL, Weaver KD, Adhikari P, Anderson DS, DeArmond PD, Mietzner TA, Crumbliss AL, Fitzgerald MC.

Biochemistry. 2008 Apr 8;47(14):4298-305. doi: 10.1021/bi701188x. Epub 2008 Mar 14.

PMID:
18338854
11.

Sulfate as a synergistic anion facilitating iron binding by the bacterial transferrin FbpA: the origins and effects of anion promiscuity.

Heymann JJ, Weaver KD, Mietzner TA, Crumbliss AL.

J Am Chem Soc. 2007 Aug 8;129(31):9704-12. Epub 2007 Jul 14.

12.

De novo-derived cationic antimicrobial peptide activity in a murine model of Pseudomonas aeruginosa bacteraemia.

Deslouches B, Gonzalez IA, DeAlmeida D, Islam K, Steele C, Montelaro RC, Mietzner TA.

J Antimicrob Chemother. 2007 Sep;60(3):669-72. Epub 2007 Jul 10.

13.

The Haemophilus influenzae hFbpABC Fe3+ transporter: analysis of the membrane permease and development of a gallium-based screen for mutants.

Anderson DS, Adhikari P, Weaver KD, Crumbliss AL, Mietzner TA.

J Bacteriol. 2007 Jul;189(14):5130-41. Epub 2007 May 11.

14.

Efficacy of the de novo-derived antimicrobial peptide WLBU2 against oral bacteria.

Novak KF, Diamond WJ, Kirakodu S, Peyyala R, Anderson KW, Montelaro RC, Mietzner TA.

Antimicrob Agents Chemother. 2007 May;51(5):1837-9. Epub 2007 Feb 26.

15.

Activity of the de novo engineered antimicrobial peptide WLBU2 against Pseudomonas aeruginosa in human serum and whole blood: implications for systemic applications.

Deslouches B, Islam K, Craigo JK, Paranjape SM, Montelaro RC, Mietzner TA.

Antimicrob Agents Chemother. 2005 Aug;49(8):3208-16.

16.

Kinetics of iron release from ferric binding protein (FbpA): mechanistic implications in bacterial periplasm-to-cytosol Fe3+ transport.

Dhungana S, Anderson DS, Mietzner TA, Crumbliss AL.

Biochemistry. 2005 Jul 19;44(28):9606-18.

PMID:
16008346
17.

Antimicrobial peptides in mucosal secretions: the importance of local secretions in mitigating infection.

Phadke SM, Deslouches B, Hileman SE, Montelaro RC, Wiesenfeld HC, Mietzner TA.

J Nutr. 2005 May;135(5):1289-93.

PMID:
15867326
18.

De novo generation of cationic antimicrobial peptides: influence of length and tryptophan substitution on antimicrobial activity.

Deslouches B, Phadke SM, Lazarevic V, Cascio M, Islam K, Montelaro RC, Mietzner TA.

Antimicrob Agents Chemother. 2005 Jan;49(1):316-22.

19.

SUPREX (Stability of Unpurified Proteins from Rates of H/D Exchange) analysis of the thermodynamics of synergistic anion binding by ferric-binding protein (FbpA), a bacterial transferrin.

Roulhac PL, Powell KD, Dhungana S, Weaver KD, Mietzner TA, Crumbliss AL, Fitzgerald MC.

Biochemistry. 2004 Dec 21;43(50):15767-74.

PMID:
15595832
20.

Phosphate ester hydrolysis is catalyzed by a bacterial transferrin: potential implications for in vivo iron transport mechanisms.

Dhungana S, Anderson DS, Mietzner TA, Crumbliss AL.

J Inorg Biochem. 2004 Nov;98(11):1975-7.

PMID:
15522424
21.
22.

Kinetics and mechanism of iron(III) complexation by ferric binding protein: the role of phosphate.

Gabricević M, Anderson DS, Mietzner TA, Crumbliss AL.

Biochemistry. 2004 May 18;43(19):5811-9.

PMID:
15134455
23.

Selective toxicity of engineered lentivirus lytic peptides in a CF airway cell model.

Phadke SM, Islam K, Deslouches B, Kapoor SA, Beer Stolz D, Watkins SC, Montelaro RC, Pilewski JM, Mietzner TA.

Peptides. 2003 Aug;24(8):1099-107.

PMID:
14612179
24.

Kinetics and mechanism of iron release from the bacterial ferric binding protein nFbp: exogenous anion influence and comparison with mammalian transferrin.

Boukhalfa H, Anderson DS, Mietzner TA, Crumbliss AL.

J Biol Inorg Chem. 2003 Nov;8(8):881-92. Epub 2003 Oct 9.

PMID:
14551810
25.

The influence of the synergistic anion on iron chelation by ferric binding protein, a bacterial transferrin.

Dhungana S, Taboy CH, Anderson DS, Vaughan KG, Aisen P, Mietzner TA, Crumbliss AL.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3659-64. Epub 2003 Mar 19.

26.

Lentivirus lytic peptide 1 perturbs both outer and inner membranes of Serratia marcescens.

Phadke SM, Lazarevic V, Bahr CC, Islam K, Stolz DB, Watkins S, Tencza SB, Vogel HJ, Montelaro RC, Mietzner TA.

Antimicrob Agents Chemother. 2002 Jun;46(6):2041-5.

27.

Crystallographic and biochemical analyses of the metal-free Haemophilus influenzae Fe3+-binding protein.

Bruns CM, Anderson DS, Vaughan KG, Williams PA, Nowalk AJ, McRee DE, Mietzner TA.

Biochemistry. 2001 Dec 25;40(51):15631-7.

PMID:
11747438
28.
29.

Fe3+ coordination and redox properties of a bacterial transferrin.

Taboy CH, Vaughan KG, Mietzner TA, Aisen P, Crumbliss AL.

J Biol Chem. 2001 Jan 26;276(4):2719-24. Epub 2000 Oct 11.

30.

Concentration-dependent differential induction of necrosis or apoptosis by HIV-1 lytic peptide 1.

Plymale DR, Comardelle AM, Fermi CD, Martin DS, Costin JM, Norris CH, Tencza SB, Mietzner TA, Montelaro RC, Garry RF.

Peptides. 1999 Nov;20(11):1275-83.

PMID:
10612441
31.

Lentivirus-derived antimicrobial peptides: increased potency by sequence engineering and dimerization.

Tencza SB, Creighton DJ, Yuan T, Vogel HJ, Montelaro RC, Mietzner TA.

J Antimicrob Chemother. 1999 Jul;44(1):33-41.

PMID:
10459808
32.

Identification of a novel Stat3 recruitment and activation motif within the granulocyte colony-stimulating factor receptor.

Chakraborty A, Dyer KF, Cascio M, Mietzner TA, Tweardy DJ.

Blood. 1999 Jan 1;93(1):15-24.

33.

Interruption of T-cell signal transduction by lentivirus lytic peptides from HIV-1 transmembrane protein.

Beary TP, Tencza SB, Mietzner TA, Montelaro RC.

J Pept Res. 1998 Jan;51(1):75-9.

PMID:
9495594
34.

A synthetic peptide corresponding to the carboxy terminus of human immunodeficiency virus type 1 transmembrane glycoprotein induces alterations in the ionic permeability of Xenopus laevis oocytes.

Comardelle AM, Norris CH, Plymale DR, Gatti PJ, Choi B, Fermin CD, Haislip AM, Tencza SB, Mietzner TA, Montelaro RC, Garry RF.

AIDS Res Hum Retroviruses. 1997 Nov 20;13(17):1525-32. Review.

PMID:
9390752
35.

Fe(III) periplasm-to-cytosol transporters of gram-negative pathogens.

Mietzner TA, Tencza SB, Adhikari P, Vaughan KG, Nowalk AJ.

Curr Top Microbiol Immunol. 1998;225:113-35. Review. No abstract available.

PMID:
9386331
36.

Novel antimicrobial peptides derived from human immunodeficiency virus type 1 and other lentivirus transmembrane proteins.

Tencza SB, Douglass JP, Creighton DJ Jr, Montelaro RC, Mietzner TA.

Antimicrob Agents Chemother. 1997 Nov;41(11):2394-8.

37.

Structure of Haemophilus influenzae Fe(+3)-binding protein reveals convergent evolution within a superfamily.

Bruns CM, Nowalk AJ, Arvai AS, McTigue MA, Vaughan KG, Mietzner TA, McRee DE.

Nat Struct Biol. 1997 Nov;4(11):919-24.

PMID:
9360608
38.

Metal-dependent conformers of the periplasmic ferric ion binding protein.

Nowalk AJ, Vaughan KG, Day BW, Tencza SB, Mietzner TA.

Biochemistry. 1997 Oct 21;36(42):13054-9.

PMID:
9335567
39.

Calmodulin-binding function of LLP segments from the HIV type 1 transmembrane protein is conserved among natural sequence variants.

Tencza SB, Mietzner TA, Montelaro RC.

AIDS Res Hum Retroviruses. 1997 Feb 10;13(3):263-9.

PMID:
9115814
40.

Functional consequences of the binding of MHC class II-derived peptides to MHC class II.

Feili-Hariri M, Kao H, Mietzner TA, Morel PA.

Int Immunol. 1996 Dec;8(12):1857-65.

PMID:
8982770
41.

The fbpABC locus of Neisseria gonorrhoeae functions in the periplasm-to-cytosol transport of iron.

Adhikari P, Berish SA, Nowalk AJ, Veraldi KL, Morse SA, Mietzner TA.

J Bacteriol. 1996 Apr;178(7):2145-9.

42.

Biochemical characterization of a Haemophilus influenzae periplasmic iron transport operon.

Adhikari P, Kirby SD, Nowalk AJ, Veraldi KL, Schryvers AB, Mietzner TA.

J Biol Chem. 1995 Oct 20;270(42):25142-9.

43.

Characterization of the calmodulin binding domain of SIV transmembrane glycoprotein by NMR and CD spectroscopy.

Yuan T, Mietzner TA, Montelaro RC, Vogel HJ.

Biochemistry. 1995 Aug 22;34(33):10690-6.

PMID:
7654723
45.

Coordination of iron by the ferric iron-binding protein of pathogenic Neisseria is homologous to the transferrins.

Nowalk AJ, Tencza SB, Mietzner TA.

Biochemistry. 1994 Nov 1;33(43):12769-75.

PMID:
7947682
46.

The role of iron-binding proteins in the survival of pathogenic bacteria.

Mietzner TA, Morse SA.

Annu Rev Nutr. 1994;14:471-93. Review. No abstract available.

PMID:
7946530
47.

Identification of a calmodulin-binding and inhibitory peptide domain in the HIV-1 transmembrane glycoprotein.

Miller MA, Mietzner TA, Cloyd MW, Robey WG, Montelaro RC.

AIDS Res Hum Retroviruses. 1993 Nov;9(11):1057-66.

PMID:
8312049
48.
49.

Alterations in cell membrane permeability by the lentivirus lytic peptide (LLP-1) of HIV-1 transmembrane protein.

Miller MA, Cloyd MW, Liebmann J, Rinaldo CR Jr, Islam KR, Wang SZ, Mietzner TA, Montelaro RC.

Virology. 1993 Sep;196(1):89-100.

PMID:
8356808

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