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Items: 9


Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib.

Miettinen TP, Peltier J, Härtlova A, Gierliński M, Jansen VM, Trost M, Björklund M.

EMBO J. 2018 May 15;37(10). pii: e98359. doi: 10.15252/embj.201798359. Epub 2018 Apr 18.


Cell size control - a mechanism for maintaining fitness and function.

Miettinen TP, Caldez MJ, Kaldis P, Björklund M.

Bioessays. 2017 Sep;39(9). doi: 10.1002/bies.201700058. Epub 2017 Jul 28. Review.


Mitochondrial Function and Cell Size: An Allometric Relationship.

Miettinen TP, Björklund M.

Trends Cell Biol. 2017 Jun;27(6):393-402. doi: 10.1016/j.tcb.2017.02.006. Epub 2017 Mar 8. Review.


Cellular Allometry of Mitochondrial Functionality Establishes the Optimal Cell Size.

Miettinen TP, Björklund M.

Dev Cell. 2016 Nov 7;39(3):370-382. doi: 10.1016/j.devcel.2016.09.004. Epub 2016 Oct 6.


The mevalonate pathway as a metabolic requirement for autophagy-implications for growth control, proteostasis, and disease.

Miettinen TP, Björklund M.

Mol Cell Oncol. 2016 Feb 18;3(3):e1143546. doi: 10.1080/23723556.2016.1143546. eCollection 2016 May.


Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy.

Miettinen TP, Björklund M.

Cell Rep. 2015 Dec 22;13(11):2610-2620. doi: 10.1016/j.celrep.2015.11.045. Epub 2015 Dec 10.


Modified ribosome profiling reveals high abundance of ribosome protected mRNA fragments derived from 3' untranslated regions.

Miettinen TP, Björklund M.

Nucleic Acids Res. 2015 Jan;43(2):1019-34. doi: 10.1093/nar/gku1310. Epub 2014 Dec 29.


NQO2 is a reactive oxygen species generating off-target for acetaminophen.

Miettinen TP, Björklund M.

Mol Pharm. 2014 Dec 1;11(12):4395-404. doi: 10.1021/mp5004866. Epub 2014 Oct 24.


Identification of transcriptional and metabolic programs related to mammalian cell size.

Miettinen TP, Pessa HK, Caldez MJ, Fuhrer T, Diril MK, Sauer U, Kaldis P, Björklund M.

Curr Biol. 2014 Mar 17;24(6):598-608. doi: 10.1016/j.cub.2014.01.071. Epub 2014 Mar 6.

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