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Items: 1 to 50 of 145

1.

Evaluation of scaffold microstructure and comparison of cell seeding methods using micro-computed tomography-based tools.

Palmroth A, Pitkänen S, Hannula M, Paakinaho K, Hyttinen J, Miettinen S, Kellomäki M.

J R Soc Interface. 2020 Apr;17(165):20200102. doi: 10.1098/rsif.2020.0102. Epub 2020 Apr 1.

PMID:
32228403
2.

Design, synthesis and characterization of a PEGylated stanozolol for potential therapeutic applications.

Vergallo C, Torrieri G, Provenzani R, Miettinen S, Moslova K, Varjosalo M, Cristiano MC, Fresta M, Celia C, Santos HA, Cilurzo F, Di Marzio L.

Int J Pharm. 2020 Jan 5;573:118826. doi: 10.1016/j.ijpharm.2019.118826. Epub 2019 Nov 9.

PMID:
31715352
3.

Co-culture of human induced pluripotent stem cell-derived retinal pigment epithelial cells and endothelial cells on double collagen-coated honeycomb films.

Calejo MT, Saari J, Vuorenpää H, Vuorimaa-Laukkanen E, Kallio P, Aalto-Setälä K, Miettinen S, Skottman H, Kellomäki M, Juuti-Uusitalo K.

Acta Biomater. 2020 Jan 1;101:327-343. doi: 10.1016/j.actbio.2019.11.002. Epub 2019 Nov 8.

4.

Tissue adhesive hyaluronic acid hydrogels for sutureless stem cell delivery and regeneration of corneal epithelium and stroma.

Koivusalo L, Kauppila M, Samanta S, Parihar VS, Ilmarinen T, Miettinen S, Oommen OP, Skottman H.

Biomaterials. 2019 Dec;225:119516. doi: 10.1016/j.biomaterials.2019.119516. Epub 2019 Sep 23.

5.

Nanofibrillar cellulose wound dressing supports the growth and characteristics of human mesenchymal stem/stromal cells without cell adhesion coatings.

Kiiskinen J, Merivaara A, Hakkarainen T, Kääriäinen M, Miettinen S, Yliperttula M, Koivuniemi R.

Stem Cell Res Ther. 2019 Sep 23;10(1):292. doi: 10.1186/s13287-019-1394-7.

6.

Cell adhesion and culture medium dependent changes in the high frequency mechanical vibration induced proliferation, osteogenesis, and intracellular organization of human adipose stem cells.

Halonen HT, Ihalainen TO, Hyväri L, Miettinen S, Hyttinen JAK.

J Mech Behav Biomed Mater. 2020 Jan;101:103419. doi: 10.1016/j.jmbbm.2019.103419. Epub 2019 Sep 5.

7.

Bioactive glass ions for in vitro osteogenesis and microvascularization in gellan gum-collagen hydrogels.

Vuornos K, Huhtala H, Kääriäinen M, Kuismanen K, Hupa L, Kellomäki M, Miettinen S.

J Biomed Mater Res B Appl Biomater. 2019 Aug 31. doi: 10.1002/jbm.b.34482. [Epub ahead of print]

PMID:
31471954
8.

Design of modular gellan gum hydrogel functionalized with avidin and biotinylated adhesive ligands for cell culture applications.

Gering C, Koivisto JT, Parraga J, Leppiniemi J, Vuornos K, Hytönen VP, Miettinen S, Kellomäki M.

PLoS One. 2019 Aug 30;14(8):e0221931. doi: 10.1371/journal.pone.0221931. eCollection 2019.

9.

The voice of paediatric oncology nurses: A longitudinal diary study of professional development.

Hopia H, Miettinen S, Miettinen M, Heino-Tolonen T.

Eur J Oncol Nurs. 2019 Oct;42:28-35. doi: 10.1016/j.ejon.2019.07.009. Epub 2019 Jul 29.

PMID:
31446261
10.

Characterisation and in vitro and in vivo evaluation of supercritical-CO2-foamed β-TCP/PLCL composites for bone applications.

Pitkänen S, Paakinaho K, Pihlman H, Ahola N, Hannula M, Asikainen S, Manninen M, Morelius M, Keränen P, Hyttinen J, Kellomäki M, Laitinen-Vapaavuori O, Miettinen S.

Eur Cell Mater. 2019 Aug 5;38:35-50. doi: 10.22203/eCM.v038a04.

11.

Diopside-tricalcium phosphate bioactive ceramics for osteogenic differentiation of human adipose stem cells.

Vanhatupa S, Miettinen S, Pena P, Baudín C.

J Biomed Mater Res B Appl Biomater. 2020 Apr;108(3):819-833. doi: 10.1002/jbm.b.34436. Epub 2019 Jun 28.

PMID:
31251466
12.

Perspectives for Clinical Translation of Adipose Stromal/Stem Cells.

Patrikoski M, Mannerström B, Miettinen S.

Stem Cells Int. 2019 May 2;2019:5858247. doi: 10.1155/2019/5858247. eCollection 2019. Review.

13.

In-vitro dissolution characteristics and human adipose stem cell response to novel borophosphate glasses.

Mishra A, Ojansivu M, Autio R, Vanhatupa S, Miettinen S, Massera J.

J Biomed Mater Res A. 2019 Sep;107(9):2099-2114. doi: 10.1002/jbm.a.36722. Epub 2019 May 23.

PMID:
31087776
14.

Combined Adipose Tissue-Derived Mesenchymal Stem Cell Therapy and Rehabilitation in Experimental Stroke.

Mu J, Bakreen A, Juntunen M, Korhonen P, Oinonen E, Cui L, Myllyniemi M, Zhao S, Miettinen S, Jolkkonen J.

Front Neurol. 2019 Mar 26;10:235. doi: 10.3389/fneur.2019.00235. eCollection 2019.

15.

Bioactive glass ions induce efficient osteogenic differentiation of human adipose stem cells encapsulated in gellan gum and collagen type I hydrogels.

Vuornos K, Ojansivu M, Koivisto JT, Häkkänen H, Belay B, Montonen T, Huhtala H, Kääriäinen M, Hupa L, Kellomäki M, Hyttinen J, Ihalainen JA, Miettinen S.

Mater Sci Eng C Mater Biol Appl. 2019 Jun;99:905-918. doi: 10.1016/j.msec.2019.02.035. Epub 2019 Feb 13.

PMID:
30889765
16.

Wood-based nanocellulose and bioactive glass modified gelatin-alginate bioinks for 3D bioprinting of bone cells.

Ojansivu M, Rashad A, Ahlinder A, Massera J, Mishra A, Syverud K, Finne-Wistrand A, Miettinen S, Mustafa K.

Biofabrication. 2019 Apr 26;11(3):035010. doi: 10.1088/1758-5090/ab0692.

PMID:
30754034
17.

S53P4 Bioactive Glass Inorganic Ions for Vascularized Bone Tissue Engineering by Dental Pulp Pluripotent-Like Stem Cell Cocultures.

Núñez-Toldrà R, Montori S, Bosch B, Hupa L, Atari M, Miettinen S.

Tissue Eng Part A. 2019 Sep;25(17-18):1213-1224. doi: 10.1089/ten.TEA.2018.0256. Epub 2019 Feb 27.

PMID:
30612528
18.

Assembly of the β4-Integrin Interactome Based on Proximal Biotinylation in the Presence and Absence of Heterodimerization.

Myllymäki SM, Kämäräinen UR, Liu X, Cruz SP, Miettinen S, Vuorela M, Varjosalo M, Manninen A.

Mol Cell Proteomics. 2019 Feb;18(2):277-293. doi: 10.1074/mcp.RA118.001095. Epub 2018 Nov 7.

19.

Genomic Characterization of Cyanophage vB_AphaS-CL131 Infecting Filamentous Diazotrophic Cyanobacterium Aphanizomenon flos-aquae Reveals Novel Insights into Virus-Bacterium Interactions.

Šulčius S, Šimoliūnas E, Alzbutas G, Gasiūnas G, Jauniškis V, Kuznecova J, Miettinen S, Nilsson E, Meškys R, Roine E, Paškauskas R, Holmfeldt K.

Appl Environ Microbiol. 2018 Dec 13;85(1). pii: e01311-18. doi: 10.1128/AEM.01311-18. Print 2019 Jan 1.

20.

Probiotic supplementation restores normal microbiota composition and function in antibiotic-treated and in caesarean-born infants.

Korpela K, Salonen A, Vepsäläinen O, Suomalainen M, Kolmeder C, Varjosalo M, Miettinen S, Kukkonen K, Savilahti E, Kuitunen M, de Vos WM.

Microbiome. 2018 Oct 16;6(1):182. doi: 10.1186/s40168-018-0567-4.

21.

Focal Adhesion Kinase and ROCK Signaling Are Switch-Like Regulators of Human Adipose Stem Cell Differentiation towards Osteogenic and Adipogenic Lineages.

Hyväri L, Ojansivu M, Juntunen M, Kartasalo K, Miettinen S, Vanhatupa S.

Stem Cells Int. 2018 Sep 12;2018:2190657. doi: 10.1155/2018/2190657. eCollection 2018.

22.

Porous poly-l-lactide-co-ɛ-caprolactone scaffold: a novel biomaterial for vaginal tissue engineering.

Sartoneva R, Kuismanen K, Juntunen M, Karjalainen S, Hannula M, Kyllönen L, Hyttinen J, Huhtala H, Paakinaho K, Miettinen S.

R Soc Open Sci. 2018 Aug 15;5(8):180811. doi: 10.1098/rsos.180811. eCollection 2018 Aug.

23.

Dislocation of large-diameter head metal-on-metal total hip arthroplasty and hip resurfacing arthroplasty.

Miettinen SSA, Mäkinen TJ, Laaksonen I, Mäkelä K, Huhtala H, Kettunen JS, Remes V.

Hip Int. 2019 May;29(3):253-261. doi: 10.1177/1120700018798302. Epub 2018 Sep 13.

PMID:
30209970
24.

The effect of S53P4-based borosilicate glasses and glass dissolution products on the osteogenic commitment of human adipose stem cells.

Ojansivu M, Mishra A, Vanhatupa S, Juntunen M, Larionova A, Massera J, Miettinen S.

PLoS One. 2018 Aug 28;13(8):e0202740. doi: 10.1371/journal.pone.0202740. eCollection 2018.

25.

Knitted 3D Scaffolds of Polybutylene Succinate Support Human Mesenchymal Stem Cell Growth and Osteogenesis.

Ojansivu M, Johansson L, Vanhatupa S, Tamminen I, Hannula M, Hyttinen J, Kellomäki M, Miettinen S.

Stem Cells Int. 2018 May 7;2018:5928935. doi: 10.1155/2018/5928935. eCollection 2018.

26.

Monocyte-derived extracellular vesicles stimulate cytokine secretion and gene expression of matrix metalloproteinases by mesenchymal stem/stromal cells.

Gebraad A, Kornilov R, Kaur S, Miettinen S, Haimi S, Peltoniemi H, Mannerström B, Seppänen-Kaijansinkko R.

FEBS J. 2018 Jun;285(12):2337-2359. doi: 10.1111/febs.14485. Epub 2018 May 18.

27.

Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks.

Sorkio A, Koch L, Koivusalo L, Deiwick A, Miettinen S, Chichkov B, Skottman H.

Biomaterials. 2018 Jul;171:57-71. doi: 10.1016/j.biomaterials.2018.04.034. Epub 2018 Apr 16.

28.

Hydrazone crosslinked hyaluronan-based hydrogels for therapeutic delivery of adipose stem cells to treat corneal defects.

Koivusalo L, Karvinen J, Sorsa E, Jönkkäri I, Väliaho J, Kallio P, Ilmarinen T, Miettinen S, Skottman H, Kellomäki M.

Mater Sci Eng C Mater Biol Appl. 2018 Apr 1;85:68-78. doi: 10.1016/j.msec.2017.12.013. Epub 2017 Dec 18.

PMID:
29407158
29.

Functional Outcome of Human Adipose Stem Cell Injections in Rat Anal Sphincter Acute Injury Model.

Kuismanen K, Juntunen M, Narra Girish N, Tuominen H, Huhtala H, Nieminen K, Hyttinen J, Miettinen S.

Stem Cells Transl Med. 2018 Mar;7(3):295-304. doi: 10.1002/sctm.17-0208. Epub 2018 Jan 31.

30.

Bioactive glass induced osteogenic differentiation of human adipose stem cells is dependent on cell attachment mechanism and mitogen-activated protein kinases.

Ojansivu M, Hyväri L, Kellomäki M, Hupa L, Vanhatupa S, Miettinen S.

Eur Cell Mater. 2018 Jan 30;35:54-72. doi: 10.22203/eCM.v035a05.

31.

Intraoperative Complications and Mid-Term Follow-Up of Large-Diameter Head Metal-on-Metal Total Hip Arthroplasty and Hip Resurfacing Arthroplasty.

Miettinen SSA, Mäkinen TJ, Mäkelä K, Huhtala H, Kettunen JS, Remes V.

Scand J Surg. 2018 Jun;107(2):180-186. doi: 10.1177/1457496917748220. Epub 2018 Jan 15.

PMID:
29333941
32.

A durable and biocompatible ascorbic acid-based covalent coating method of polydimethylsiloxane for dynamic cell culture.

Leivo J, Virjula S, Vanhatupa S, Kartasalo K, Kreutzer J, Miettinen S, Kallio P.

J R Soc Interface. 2017 Jul;14(132). pii: 20170318. doi: 10.1098/rsif.2017.0318.

33.

Cranioplasty with Adipose-Derived Stem Cells, Beta-Tricalcium Phosphate Granules and Supporting Mesh: Six-Year Clinical Follow-Up Results.

Thesleff T, Lehtimäki K, Niskakangas T, Huovinen S, Mannerström B, Miettinen S, Seppänen-Kaijansinkko R, Öhman J.

Stem Cells Transl Med. 2017 Jul;6(7):1576-1582. doi: 10.1002/sctm.16-0410. Epub 2017 May 15.

34.

Effects of Macromolecular Crowding on Human Adipose Stem Cell Culture in Fetal Bovine Serum, Human Serum, and Defined Xeno-Free/Serum-Free Conditions.

Patrikoski M, Lee MHC, Mäkinen L, Ang XM, Mannerström B, Raghunath M, Miettinen S.

Stem Cells Int. 2017;2017:6909163. doi: 10.1155/2017/6909163. Epub 2017 Mar 30.

35.

Comparison of Poly(l-lactide-co-ɛ-caprolactone) and Poly(trimethylene carbonate) Membranes for Urethral Regeneration: An In Vitro and In Vivo Study.

Sartoneva R, Nordback PH, Haimi S, Grijpma DW, Lehto K, Rooney N, Seppänen-Kaijansinkko R, Miettinen S, Lahdes-Vasama T.

Tissue Eng Part A. 2018 Jan;24(1-2):117-127. doi: 10.1089/ten.TEA.2016.0245. Epub 2017 Jul 21.

PMID:
28463605
36.

The effect of equiaxial stretching on the osteogenic differentiation and mechanical properties of human adipose stem cells.

Virjula S, Zhao F, Leivo J, Vanhatupa S, Kreutzer J, Vaughan TJ, Honkala AM, Viehrig M, Mullen CA, Kallio P, McNamara LM, Miettinen S.

J Mech Behav Biomed Mater. 2017 Aug;72:38-48. doi: 10.1016/j.jmbbm.2017.04.016. Epub 2017 Apr 13.

PMID:
28448920
37.

Electrically Stimulated Adipose Stem Cells on Polypyrrole-Coated Scaffolds for Smooth Muscle Tissue Engineering.

Björninen M, Gilmore K, Pelto J, Seppänen-Kaijansinkko R, Kellomäki M, Miettinen S, Wallace G, Grijpma D, Haimi S.

Ann Biomed Eng. 2017 Apr;45(4):1015-1026. doi: 10.1007/s10439-016-1755-7. Epub 2016 Nov 14.

PMID:
27844175
38.

UV Cross-Linkable Graphene/Poly(trimethylene Carbonate) Composites for 3D Printing of Electrically Conductive Scaffolds.

Sayyar S, Bjorninen M, Haimi S, Miettinen S, Gilmore K, Grijpma D, Wallace G.

ACS Appl Mater Interfaces. 2016 Nov 23;8(46):31916-31925. Epub 2016 Nov 10.

PMID:
27782383
39.

Optical non-contact pH measurement in cell culture with sterilizable, modular parts.

Kattipparambil Rajan D, Patrikoski M, Verho J, Sivula J, Ihalainen H, Miettinen S, Lekkala J.

Talanta. 2016 Dec 1;161:755-761. doi: 10.1016/j.talanta.2016.09.021. Epub 2016 Sep 8.

PMID:
27769477
40.

Time-scale dynamics of proteome and transcriptome of the white-rot fungus Phlebia radiata: growth on spruce wood and decay effect on lignocellulose.

Kuuskeri J, Häkkinen M, Laine P, Smolander OP, Tamene F, Miettinen S, Nousiainen P, Kemell M, Auvinen P, Lundell T.

Biotechnol Biofuels. 2016 Sep 5;9(1):192. doi: 10.1186/s13068-016-0608-9. eCollection 2016.

41.

Early aseptic loosening of cementless monoblock acetabular components.

Miettinen SS, Mäkinen TJ, Laaksonen I, Mäkelä K, Huhtala H, Kettunen J, Remes V.

Int Orthop. 2017 Apr;41(4):715-722. doi: 10.1007/s00264-016-3254-8. Epub 2016 Aug 10.

PMID:
27506571
42.

Differentiation of adipose stem cells seeded towards annulus fibrosus cells on a designed poly(trimethylene carbonate) scaffold prepared by stereolithography.

Blanquer SBG, Gebraad AWH, Miettinen S, Poot AA, Grijpma DW, Haimi SP.

J Tissue Eng Regen Med. 2017 Oct;11(10):2752-2762. doi: 10.1002/term.2170. Epub 2016 Jul 4.

PMID:
27375236
43.

Human Adipose Stem Cells Differentiated on Braided Polylactide Scaffolds Is a Potential Approach for Tendon Tissue Engineering.

Vuornos K, Björninen M, Talvitie E, Paakinaho K, Kellomäki M, Huhtala H, Miettinen S, Seppänen-Kaijansinkko R, Haimi S.

Tissue Eng Part A. 2016 Mar;22(5-6):513-23. doi: 10.1089/ten.tea.2015.0276. Epub 2016 Feb 26.

PMID:
26919401
44.

Bone healing in rabbit calvarial critical-sized defects filled with stem cells and growth factors combined with granular or solid scaffolds.

Lappalainen OP, Karhula S, Haapea M, Kyllönen L, Haimi S, Miettinen S, Saarakkala S, Korpi J, Ylikontiola LP, Serlo WS, Sándor GK.

Childs Nerv Syst. 2016 Apr;32(4):681-8. doi: 10.1007/s00381-016-3017-2. Epub 2016 Jan 19.

PMID:
26782995
45.

Polypyrrole coating on poly-(lactide/glycolide)-β-tricalcium phosphate screws enhances new bone formation in rabbits.

Zhao MD, Björninen M, Cao L, Wang HR, Pelto J, Li XQ, Hyttinen J, Jiang YQ, Kellomäki M, Miettinen S, Sándor GK, Seppänen R, Haimi S, Dong J.

Biomed Mater. 2015 Nov 27;10(6):065016. doi: 10.1088/1748-6041/10/6/065016.

PMID:
26610717
46.

Biotin-dependent functions in adiposity: a study of monozygotic twin pairs.

Järvinen E, Ismail K, Muniandy M, Bogl LH, Heinonen S, Tummers M, Miettinen S, Kaprio J, Rissanen A, Ollikainen M, Pietiläinen KH.

Int J Obes (Lond). 2016 May;40(5):788-95. doi: 10.1038/ijo.2015.237. Epub 2015 Nov 25.

PMID:
26601567
47.

Risk factors for intraoperative calcar fracture in cementless total hip arthroplasty.

Miettinen SS, Mäkinen TJ, Kostensalo I, Mäkelä K, Huhtala H, Kettunen JS, Remes V.

Acta Orthop. 2016;87(2):113-9. doi: 10.3109/17453674.2015.1112712. Epub 2015 Nov 6.

48.

Bone Morphogenetic Protein-2 Induces Donor-Dependent Osteogenic and Adipogenic Differentiation in Human Adipose Stem Cells.

Vanhatupa S, Ojansivu M, Autio R, Juntunen M, Miettinen S.

Stem Cells Transl Med. 2015 Dec;4(12):1391-402. doi: 10.5966/sctm.2015-0042. Epub 2015 Oct 22.

49.

Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles.

Haapasalo K, van Kessel K, Nissilä E, Metso J, Johansson T, Miettinen S, Varjosalo M, Kirveskari J, Kuusela P, Chroni A, Jauhiainen M, van Strijp J, Jokiranta TS.

J Biol Chem. 2015 Nov 27;290(48):28977-87. doi: 10.1074/jbc.M115.669226. Epub 2015 Oct 14.

50.

Chitosan membranes in a rat model of full-thickness cutaneous wounds: healing and IL-4 levels.

Nordback PH, Miettinen S, Kääriäinen M, Haaparanta AM, Kellomäki M, Kuokkanen H, Seppänen R.

J Wound Care. 2015 Jun;24(6):245-6, 248-51. doi: 10.12968/jowc.2015.24.6.245.

PMID:
26075372

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