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Items: 34


Semisynthesis and biological evaluation of amidochelocardin derivatives as broad-spectrum antibiotics.

Grandclaudon C, Birudukota NVS, Elgaher WAM, Jumde RP, Yahiaoui S, Arisetti N, Hennessen F, Hüttel S, Stadler M, Herrmann J, Miethke M, Hartmann RW, Müller R, Hirsch AKH, Brönstrup M.

Eur J Med Chem. 2020 Feb 15;188:112005. doi: 10.1016/j.ejmech.2019.112005. Epub 2019 Dec 20.


Aurantimycin resistance genes contribute to survival of Listeria monocytogenes during life in the environment.

Hauf S, Herrmann J, Miethke M, Gibhardt J, Commichau FM, Müller R, Fuchs S, Halbedel S.

Mol Microbiol. 2019 Apr;111(4):1009-1024. doi: 10.1111/mmi.14205. Epub 2019 Feb 27.


Teledermatology Implementation in a VHA Secondary Treatment Facility Improves Access to Face-to-Face Care.

Raugi GJ, Nelson W, Miethke M, Boyd M, Markham C, Dougall B, Bratten D, Comer T.

Telemed J E Health. 2016 Jan;22(1):12-7. doi: 10.1089/tmj.2015.0036. Epub 2015 Sep 22.


Molecular insights into frataxin-mediated iron supply for heme biosynthesis in Bacillus subtilis.

Mielcarek A, Blauenburg B, Miethke M, Marahiel MA.

PLoS One. 2015 Mar 31;10(3):e0122538. doi: 10.1371/journal.pone.0122538. eCollection 2015.


Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas.

Hong-Hermesdorf A, Miethke M, Gallaher SD, Kropat J, Dodani SC, Chan J, Barupala D, Domaille DW, Shirasaki DI, Loo JA, Weber PK, Pett-Ridge J, Stemmler TL, Chang CJ, Merchant SS.

Nat Chem Biol. 2015 Mar;11(3):235. doi: 10.1038/nchembio0315-235c. No abstract available.


Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas.

Hong-Hermesdorf A, Miethke M, Gallaher SD, Kropat J, Dodani SC, Chan J, Barupala D, Domaille DW, Shirasaki DI, Loo JA, Weber PK, Pett-Ridge J, Stemmler TL, Chang CJ, Merchant SS.

Nat Chem Biol. 2014 Dec;10(12):1034-42. doi: 10.1038/nchembio.1662. Epub 2014 Oct 26. Erratum in: Nat Chem Biol. 2015 Mar;11(3):235.


The Bacillus subtilis EfeUOB transporter is essential for high-affinity acquisition of ferrous and ferric iron.

Miethke M, Monteferrante CG, Marahiel MA, van Dijl JM.

Biochim Biophys Acta. 2013 Oct;1833(10):2267-78. doi: 10.1016/j.bbamcr.2013.05.027. Epub 2013 Jun 10.


Uptake of xenosiderophores in Bacillus subtilis occurs with high affinity and enhances the folding stabilities of substrate binding proteins.

Miethke M, Kraushaar T, Marahiel MA.

FEBS Lett. 2013 Jan 16;587(2):206-13. doi: 10.1016/j.febslet.2012.11.027. Epub 2012 Dec 5.


Molecular strategies of microbial iron assimilation: from high-affinity complexes to cofactor assembly systems.

Miethke M.

Metallomics. 2013 Jan;5(1):15-28. doi: 10.1039/c2mt20193c. Review.


Specific targeting of the metallophosphoesterase YkuE to the bacillus cell wall requires the twin-arginine translocation system.

Monteferrante CG, Miethke M, van der Ploeg R, Glasner C, van Dijl JM.

J Biol Chem. 2012 Aug 24;287(35):29789-800. doi: 10.1074/jbc.M112.378190. Epub 2012 Jul 5.


The siderophore-interacting protein YqjH acts as a ferric reductase in different iron assimilation pathways of Escherichia coli.

Miethke M, Hou J, Marahiel MA.

Biochemistry. 2011 Dec 20;50(50):10951-64. doi: 10.1021/bi201517h. Epub 2011 Nov 18.


The siderophore binding protein FeuA shows limited promiscuity toward exogenous triscatecholates.

Peuckert F, Ramos-Vega AL, Miethke M, Schwörer CJ, Albrecht AG, Oberthür M, Marahiel MA.

Chem Biol. 2011 Jul 29;18(7):907-19. doi: 10.1016/j.chembiol.2011.05.006.


The frataxin homologue Fra plays a key role in intracellular iron channeling in Bacillus subtilis.

Albrecht AG, Landmann H, Nette D, Burghaus O, Peuckert F, Seubert A, Miethke M, Marahiel MA.

Chembiochem. 2011 Sep 5;12(13):2052-61. doi: 10.1002/cbic.201100190. Epub 2011 Jul 8.


Environmental salinity determines the specificity and need for Tat-dependent secretion of the YwbN protein in Bacillus subtilis.

van der Ploeg R, Mäder U, Homuth G, Schaffer M, Denham EL, Monteferrante CG, Miethke M, Marahiel MA, Harwood CR, Winter T, Hecker M, Antelmann H, van Dijl JM.

PLoS One. 2011 Mar 30;6(3):e18140. doi: 10.1371/journal.pone.0018140.


Mechanistic characterization of sulfur transfer from cysteine desulfurase SufS to the iron-sulfur scaffold SufU in Bacillus subtilis.

Albrecht AG, Peuckert F, Landmann H, Miethke M, Seubert A, Marahiel MA.

FEBS Lett. 2011 Feb 4;585(3):465-70. doi: 10.1016/j.febslet.2011.01.005. Epub 2011 Jan 12.


Direct identification of a siderophore import protein using synthetic petrobactin ligands.

Bugdahn N, Peuckert F, Albrecht AG, Miethke M, Marahiel MA, Oberthür M.

Angew Chem Int Ed Engl. 2010 Dec 27;49(52):10210-3. doi: 10.1002/anie.201005527. No abstract available.


Identification and characterization of a novel-type ferric siderophore reductase from a gram-positive extremophile.

Miethke M, Pierik AJ, Peuckert F, Seubert A, Marahiel MA.

J Biol Chem. 2011 Jan 21;286(3):2245-60. doi: 10.1074/jbc.M110.192468. Epub 2010 Nov 4.


Copper stress affects iron homeostasis by destabilizing iron-sulfur cluster formation in Bacillus subtilis.

Chillappagari S, Seubert A, Trip H, Kuipers OP, Marahiel MA, Miethke M.

J Bacteriol. 2010 May;192(10):2512-24. doi: 10.1128/JB.00058-10. Epub 2010 Mar 16.


SufU is an essential iron-sulfur cluster scaffold protein in Bacillus subtilis.

Albrecht AG, Netz DJ, Miethke M, Pierik AJ, Burghaus O, Peuckert F, Lill R, Marahiel MA.

J Bacteriol. 2010 Mar;192(6):1643-51. doi: 10.1128/JB.01536-09. Epub 2010 Jan 22.


Neutrophil gelatinase-associated lipocalin expresses antimicrobial activity by interfering with L-norepinephrine-mediated bacterial iron acquisition.

Miethke M, Skerra A.

Antimicrob Agents Chemother. 2010 Apr;54(4):1580-9. doi: 10.1128/AAC.01158-09. Epub 2010 Jan 19.


Structural basis and stereochemistry of triscatecholate siderophore binding by FeuA.

Peuckert F, Miethke M, Albrecht AG, Essen LO, Marahiel MA.

Angew Chem Int Ed Engl. 2009;48(42):7924-7. doi: 10.1002/anie.200902495. No abstract available.


Copper acquisition is mediated by YcnJ and regulated by YcnK and CsoR in Bacillus subtilis.

Chillappagari S, Miethke M, Trip H, Kuipers OP, Marahiel MA.

J Bacteriol. 2009 Apr;191(7):2362-70. doi: 10.1128/JB.01616-08. Epub 2009 Jan 23.


The major facilitator superfamily-type transporter YmfE and the multidrug-efflux activator Mta mediate bacillibactin secretion in Bacillus subtilis.

Miethke M, Schmidt S, Marahiel MA.

J Bacteriol. 2008 Aug;190(15):5143-52. doi: 10.1128/JB.00464-08. Epub 2008 May 23.


The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features.

Seedorf H, Fricke WF, Veith B, Brüggemann H, Liesegang H, Strittmatter A, Miethke M, Buckel W, Hinderberger J, Li F, Hagemeier C, Thauer RK, Gottschalk G.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2128-33. doi: 10.1073/pnas.0711093105. Epub 2008 Jan 24.


Siderophore-based iron acquisition and pathogen control.

Miethke M, Marahiel MA.

Microbiol Mol Biol Rev. 2007 Sep;71(3):413-51. Review.


Fully automated quantification of hepatitis C virus (HCV) RNA in human plasma and human serum by the COBAS AmpliPrep/COBAS TaqMan system.

Sizmann D, Boeck C, Boelter J, Fischer D, Miethke M, Nicolaus S, Zadak M, Babiel R.

J Clin Virol. 2007 Apr;38(4):326-33. Epub 2007 Mar 6.


Iron starvation triggers the stringent response and induces amino acid biosynthesis for bacillibactin production in Bacillus subtilis.

Miethke M, Westers H, Blom EJ, Kuipers OP, Marahiel MA.

J Bacteriol. 2006 Dec;188(24):8655-7. Epub 2006 Sep 29.


Ferri-bacillibactin uptake and hydrolysis in Bacillus subtilis.

Miethke M, Klotz O, Linne U, May JJ, Beckering CL, Marahiel MA.

Mol Microbiol. 2006 Sep;61(6):1413-27. Epub 2006 Aug 3.


Involvement of Bacillus subtilis ClpE in CtsR degradation and protein quality control.

Miethke M, Hecker M, Gerth U.

J Bacteriol. 2006 Jul;188(13):4610-9.


Inhibition of aryl acid adenylation domains involved in bacterial siderophore synthesis.

Miethke M, Bisseret P, Beckering CL, Vignard D, Eustache J, Marahiel MA.

FEBS J. 2006 Jan;273(2):409-19.


The extracellular and cytoplasmic proteomes of the non-virulent Bacillus anthracis strain UM23C1-2.

Antelmann H, Williams RC, Miethke M, Wipat A, Albrecht D, Harwood CR, Hecker M.

Proteomics. 2005 Sep;5(14):3684-95.


Post-transcriptional regulation of the Bacillus subtilis pst operon encoding a phosphate-specific ABC transporter.

Allenby NEE, O'Connor N, Prágai Z, Carter NM, Miethke M, Engelmann S, Hecker M, Wipat A, Ward AC, Harwood CR.

Microbiology. 2004 Aug;150(Pt 8):2619-2628. doi: 10.1099/mic.0.27126-0.


Fine-tuning in regulation of Clp protein content in Bacillus subtilis.

Gerth U, Kirstein J, Mostertz J, Waldminghaus T, Miethke M, Kock H, Hecker M.

J Bacteriol. 2004 Jan;186(1):179-91.


The composition of the ceramides from human stratum corneum and from comedones.

Wertz PW, Miethke MC, Long SA, Strauss JS, Downing DT.

J Invest Dermatol. 1985 May;84(5):410-2.

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