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Items: 22


A Promiscuous CYP706A3 Reduces Terpene Volatile Emission from Arabidopsis Flowers, Affecting Florivores and the Floral Microbiome.

Boachon B, Burdloff Y, Ruan JX, Rojo R, Junker RR, Vincent B, Nicolè F, Bringel F, Lesot A, Henry L, Bassard JE, Mathieu S, Allouche L, Kaplan I, Dudareva N, Vuilleumier S, Miesch L, André F, Navrot N, Chen XY, Werck D.

Plant Cell. 2019 Oct 18. pii: tpc.00320.2019. doi: 10.1105/tpc.19.00320. [Epub ahead of print]


Characterization of Jasmonoyl-Isoleucine (JA-Ile) Hormonal Catabolic Pathways in Rice upon Wounding and Salt Stress.

Hazman M, Sühnel M, Schäfer S, Zumsteg J, Lesot A, Beltran F, Marquis V, Herrgott L, Miesch L, Riemann M, Heitz T.

Rice (N Y). 2019 Jun 25;12(1):45. doi: 10.1186/s12284-019-0303-0.


Metal-free synthesis of activated ynesulfonamides and tertiary enesulfonamides.

Andna L, Miesch L.

Org Biomol Chem. 2019 Jun 12;17(23):5688-5692. doi: 10.1039/c9ob00947g.


Tertiary Enamide-Triggered SEAr: Domino Allylation and Enamine-Type Addition.

Beltran F, Miesch L.

Org Lett. 2019 Mar 15;21(6):1569-1573. doi: 10.1021/acs.orglett.8b03987. Epub 2019 Feb 26.


Trapping of N-Acyliminium Ions with Enamides: An Approach to Medium-Sized Diaza-Heterocycles.

Andna L, Miesch L.

Org Lett. 2018 Jun 1;20(11):3430-3433. doi: 10.1021/acs.orglett.8b01407. Epub 2018 May 23.


Direct Spirocyclization from Keto-sulfonamides: An Approach to Azaspiro Compounds.

Beltran F, Fabre I, Ciofini I, Miesch L.

Org Lett. 2017 Oct 6;19(19):5042-5045. doi: 10.1021/acs.orglett.7b02216. Epub 2017 Sep 20.


Jasmonic Acid Oxidase 2 Hydroxylates Jasmonic Acid and Represses Basal Defense and Resistance Responses against Botrytis cinerea Infection.

Smirnova E, Marquis V, Poirier L, Aubert Y, Zumsteg J, Ménard R, Miesch L, Heitz T.

Mol Plant. 2017 Sep 12;10(9):1159-1173. doi: 10.1016/j.molp.2017.07.010. Epub 2017 Jul 29.


A grapevine cytochrome P450 generates the precursor of wine lactone, a key odorant in wine.

Ilc T, Halter D, Miesch L, Lauvoisard F, Kriegshauser L, Ilg A, Baltenweck R, Hugueney P, Werck-Reichhart D, Duchêne E, Navrot N.

New Phytol. 2017 Jan;213(1):264-274. doi: 10.1111/nph.14139. Epub 2016 Aug 25.


Dynamics of Jasmonate Metabolism upon Flowering and across Leaf Stress Responses in Arabidopsis thaliana.

Widemann E, Smirnova E, Aubert Y, Miesch L, Heitz T.

Plants (Basel). 2016 Jan 6;5(1). pii: E4. doi: 10.3390/plants5010004.


Silver-Catalyzed 7-exo-dig Cyclization of Silylenolether-ynesulfonamides.

Heinrich CF, Fabre I, Miesch L.

Angew Chem Int Ed Engl. 2016 Apr 18;55(17):5170-4. doi: 10.1002/anie.201510708. Epub 2016 Mar 22.


CYP76C1 (Cytochrome P450)-Mediated Linalool Metabolism and the Formation of Volatile and Soluble Linalool Oxides in Arabidopsis Flowers: A Strategy for Defense against Floral Antagonists.

Boachon B, Junker RR, Miesch L, Bassard JE, Höfer R, Caillieaudeaux R, Seidel DE, Lesot A, Heinrich C, Ginglinger JF, Allouche L, Vincent B, Wahyuni DS, Paetz C, Beran F, Miesch M, Schneider B, Leiss K, Werck-Reichhart D.

Plant Cell. 2015 Oct;27(10):2972-90. doi: 10.1105/tpc.15.00399. Epub 2015 Oct 16.


Sequential oxidation of Jasmonoyl-Phenylalanine and Jasmonoyl-Isoleucine by multiple cytochrome P450 of the CYP94 family through newly identified aldehyde intermediates.

Widemann E, Grausem B, Renault H, Pineau E, Heinrich C, Lugan R, Ullmann P, Miesch L, Aubert Y, Miesch M, Heitz T, Pinot F.

Phytochemistry. 2015 Sep;117:388-399. doi: 10.1016/j.phytochem.2015.06.027. Epub 2015 Jul 9.


CYP94-mediated jasmonoyl-isoleucine hormone oxidation shapes jasmonate profiles and attenuates defence responses to Botrytis cinerea infection.

Aubert Y, Widemann E, Miesch L, Pinot F, Heitz T.

J Exp Bot. 2015 Jul;66(13):3879-92. doi: 10.1093/jxb/erv190. Epub 2015 Apr 22.


In situ intramolecular catalytic 1,2-addition of allenoates to cyclic ketones towards polycyclic allenoates.

Heinrich CF, Miesch M, Miesch L.

Org Biomol Chem. 2015 Feb 21;13(7):2153-6. doi: 10.1039/c4ob02451f.


Dual function of the cytochrome P450 CYP76 family from Arabidopsis thaliana in the metabolism of monoterpenols and phenylurea herbicides.

Höfer R, Boachon B, Renault H, Gavira C, Miesch L, Iglesias J, Ginglinger JF, Allouche L, Miesch M, Grec S, Larbat R, Werck-Reichhart D.

Plant Physiol. 2014 Nov;166(3):1149-61. doi: 10.1104/pp.114.244814. Epub 2014 Jul 31.


Gene coexpression analysis reveals complex metabolism of the monoterpene alcohol linalool in Arabidopsis flowers.

Ginglinger JF, Boachon B, Höfer R, Paetz C, Köllner TG, Miesch L, Lugan R, Baltenweck R, Mutterer J, Ullmann P, Beran F, Claudel P, Verstappen F, Fischer MJ, Karst F, Bouwmeester H, Miesch M, Schneider B, Gershenzon J, Ehlting J, Werck-Reichhart D.

Plant Cell. 2013 Nov;25(11):4640-57. doi: 10.1105/tpc.113.117382. Epub 2013 Nov 27.


The amidohydrolases IAR3 and ILL6 contribute to jasmonoyl-isoleucine hormone turnover and generate 12-hydroxyjasmonic acid upon wounding in Arabidopsis leaves.

Widemann E, Miesch L, Lugan R, Holder E, Heinrich C, Aubert Y, Miesch M, Pinot F, Heitz T.

J Biol Chem. 2013 Nov 1;288(44):31701-14. doi: 10.1074/jbc.M113.499228. Epub 2013 Sep 19.


Stereoselective cross aldol condensation of bicyclo[3.2.0]alkanones.

Miesch L, Welsch T, Miesch M.

Org Biomol Chem. 2013 Jun 28;11(24):4025-9. doi: 10.1039/c3ob40431e.


A silver-catalyzed spirocyclization of alkynyl silyl enol ethers.

Schäfer C, Miesch M, Miesch L.

Chemistry. 2012 Jun 25;18(26):8028-31. doi: 10.1002/chem.201200116. Epub 2012 Jun 1.


Intramolecular reductive ketone-alkynoate coupling reaction promoted by (η2-propene)titanium.

Schäfer C, Miesch M, Miesch L.

Org Biomol Chem. 2012 Apr 28;10(16):3253-7. doi: 10.1039/c2ob07049a. Epub 2012 Mar 12.


Cytochromes P450 CYP94C1 and CYP94B3 catalyze two successive oxidation steps of plant hormone Jasmonoyl-isoleucine for catabolic turnover.

Heitz T, Widemann E, Lugan R, Miesch L, Ullmann P, Désaubry L, Holder E, Grausem B, Kandel S, Miesch M, Werck-Reichhart D, Pinot F.

J Biol Chem. 2012 Feb 24;287(9):6296-306. doi: 10.1074/jbc.M111.316364. Epub 2012 Jan 3.


Intramolecular alkynylogous mukaiyama aldol reaction starting from bicyclic alkanones tethered to alkynyl esters: formal total synthesis of (+/-)-hamigeran B.

Miesch L, Welsch T, Rietsch V, Miesch M.

Chemistry. 2009;15(17):4394-401. doi: 10.1002/chem.200802309.


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