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Items: 25

1.

High-level expression of Lactobacillus beta-galactosidases in Lactococcus lactis using the food-grade, nisin-controlled expression system NICE.

Maischberger T, Mierau I, Peterbauer CK, Hugenholtz J, Haltrich D.

J Agric Food Chem. 2010 Feb 24;58(4):2279-87. doi: 10.1021/jf902895g.

PMID:
20092320
2.

10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis.

Mierau I, Kleerebezem M.

Appl Microbiol Biotechnol. 2005 Oct;68(6):705-17. Epub 2005 Oct 13. Review.

PMID:
16088349
3.
4.
5.

Controlled modulation of folate polyglutamyl tail length by metabolic engineering of Lactococcus lactis.

Sybesma W, Van Den Born E, Starrenburg M, Mierau I, Kleerebezem M, De Vos WM, Hugenholtz J.

Appl Environ Microbiol. 2003 Dec;69(12):7101-7.

6.

Increased production of folate by metabolic engineering of Lactococcus lactis.

Sybesma W, Starrenburg M, Kleerebezem M, Mierau I, de Vos WM, Hugenholtz J.

Appl Environ Microbiol. 2003 Jun;69(6):3069-76.

7.

Metabolic engineering of acetaldehyde production by Streptococcus thermophilus.

Chaves AC, Fernandez M, Lerayer AL, Mierau I, Kleerebezem M, Hugenholtz J.

Appl Environ Microbiol. 2002 Nov;68(11):5656-62.

8.

Metabolic engineering of Lactococcus lactis: the impact of genomics and metabolic modelling.

Kleerebezem M, Boels IC, Groot MN, Mierau I, Sybesma W, Hugenholtz J.

J Biotechnol. 2002 Sep 25;98(2-3):199-213. Review.

PMID:
12141987
9.

Measurement of parameters of cholic acid kinetics in plasma using a microscale stable isotope dilution technique: application to rodents and humans.

Hulzebos CV, Renfurm L, Bandsma RH, Verkade HJ, Boer T, Boverhof R, Tanaka H, Mierau I, Sauer PJ, Kuipers F, Stellaard F.

J Lipid Res. 2001 Nov;42(11):1923-9.

10.

Improved efficiency and reliability of RT-PCR using tag-extended RT primers and temperature gradient PCR.

Sybesma W, Hugenholtz J, Mierau I, Kleerebezem M.

Biotechniques. 2001 Sep;31(3):466, 468, 470, passim. No abstract available.

11.

Cholic acid is accumulated spontaneously, driven by membrane deltapH, in many lactobacilli.

Kurdi P, van Veen HW, Tanaka H, Mierau I, Konings WN, Tannock GW, Tomita F, Yokota A.

J Bacteriol. 2000 Nov;182(22):6525-8.

12.

Bile salt hydrolase of Bifidobacterium longum-biochemical and genetic characterization.

Tanaka H, Hashiba H, Kok J, Mierau I.

Appl Environ Microbiol. 2000 Jun;66(6):2502-12.

13.

Screening of lactic acid bacteria for bile salt hydrolase activity.

Tanaka H, Doesburg K, Iwasaki T, Mierau I.

J Dairy Sci. 1999 Dec;82(12):2530-5.

14.

Purification and characterization of bovine pancreatic bile salt-activated lipase.

Tanaka H, Mierau I, Ito F.

J Biochem. 1999 May;125(5):883-90.

15.

Cloning and analysis of the pepV dipeptidase gene of Lactococcus lactis MG1363.

Hellendoorn MA, Franke-Fayard BM, Mierau I, Venema G, Kok J.

J Bacteriol. 1997 Jun;179(11):3410-5.

16.

Casein and peptide degradation in lactic acid bacteria.

Mierau I, Kunji ER, Venema G, Kok J.

Biotechnol Genet Eng Rev. 1997;14:279-301. Review. No abstract available.

PMID:
9188156
17.

A general system for generating unlabelled gene replacements in bacterial chromosomes.

Leenhouts K, Buist G, Bolhuis A, ten Berge A, Kiel J, Mierau I, Dabrowska M, Venema G, Kok J.

Mol Gen Genet. 1996 Nov 27;253(1-2):217-24.

PMID:
9003306
18.

The proteolytic systems of lactic acid bacteria.

Kunji ER, Mierau I, Hagting A, Poolman B, Konings WN.

Antonie Van Leeuwenhoek. 1996 Oct;70(2-4):187-221. Review.

PMID:
8879407
19.

Heterologous expression and characterization of recombinant Lactococcus lactis neutral endopeptidase (neprilysin).

Lian W, Wu D, Konings WN, Mierau I, Hersh LB.

Arch Biochem Biophys. 1996 Sep 1;333(1):121-6.

PMID:
8806762
20.

Fate of peptides in peptidase mutants of Lactococcus lactis.

Kunji ER, Mierau I, Poolman B, Konings WN, Venema G, Kok J.

Mol Microbiol. 1996 Jul;21(1):123-31.

PMID:
8843439
21.

Multiple-peptidase mutants of Lactococcus lactis are severely impaired in their ability to grow in milk.

Mierau I, Kunji ER, Leenhouts KJ, Hellendoorn MA, Haandrikman AJ, Poolman B, Konings WN, Venema G, Kok J.

J Bacteriol. 1996 May;178(10):2794-803.

22.

Novel insertion sequence-like element IS982 in lactococci.

Yu W, Mierau I, Mars A, Johnson E, Dunny G, McKay LL.

Plasmid. 1995 May;33(3):218-25.

PMID:
7568469
23.

Genetics of peptide degradation in Lactococcus: gene cloning, construction and analysis of peptidase negative mutants.

Mierau I, Haandrikman AJ, Leenhouts KJ, Tan PS, Konings WN, Venema G, Kok J.

Dev Biol Stand. 1995;85:503-7. No abstract available.

PMID:
8586223
24.

Tripeptidase gene (pepT) of Lactococcus lactis: molecular cloning and nucleotide sequencing of pepT and construction of a chromosomal deletion mutant.

Mierau I, Haandrikman AJ, Velterop O, Tan PS, Leenhouts KL, Konings WN, Venema G, Kok J.

J Bacteriol. 1994 May;176(10):2854-61.

25.

Cloning and sequencing of the gene for a lactococcal endopeptidase, an enzyme with sequence similarity to mammalian enkephalinase.

Mierau I, Tan PS, Haandrikman AJ, Mayo B, Kok J, Leenhouts KJ, Konings WN, Venema G.

J Bacteriol. 1993 Apr;175(7):2087-96. Erratum in: J Bacteriol 1993 Jun;175(12):3918.

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