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Items: 1 to 50 of 53

1.

Biomarker discovery in cardiac allograft vasculopathy using targeted aptamer proteomics.

Almufleh A, Zhang L, Mielniczuk LM, Stadnick E, Davies RA, Du Q, Rayner K, Liu PP, Chih S.

Clin Transplant. 2019 Dec 9:e13765. doi: 10.1111/ctr.13765. [Epub ahead of print]

PMID:
31815308
2.

Reliable quantification of myocardial sympathetic innervation and regional denervation using [11C]meta-hydroxyephedrine PET.

Wu KY, Zelt JGE, Wang T, Dinculescu V, Miner R, Lapierre C, Kaps N, Lavallee A, Renaud JM, Thackeray J, Mielniczuk LM, Chen SY, Burwash IG, DaSilva JN, Beanlands RSB, deKemp RA.

Eur J Nucl Med Mol Imaging. 2019 Dec 9. doi: 10.1007/s00259-019-04629-5. [Epub ahead of print]

PMID:
31814069
3.

The Current Role of Viability Imaging to Guide Revascularization and Therapy Decisions in Patients With Heart Failure and Reduced Left Ventricular Function.

Kandolin RM, Wiefels CC, Mesquita CT, Chong AY, Boland P, Glineur D, Sun L, Beanlands RS, Mielniczuk LM.

Can J Cardiol. 2019 Aug;35(8):1015-1029. doi: 10.1016/j.cjca.2019.04.029. Epub 2019 May 24. Review.

PMID:
31376903
4.

Nuclear Imaging of the Cardiac Sympathetic Nervous System: A Disease-Specific Interpretation in Heart Failure.

Zelt JGE, deKemp RA, Rotstein BH, Nair GM, Narula J, Ahmadi A, Beanlands RS, Mielniczuk LM.

JACC Cardiovasc Imaging. 2019 Jul 11. pii: S1936-878X(19)30582-0. doi: 10.1016/j.jcmg.2019.01.042. [Epub ahead of print] Review.

PMID:
31326479
5.

Medical Therapy for Heart Failure Associated With Pulmonary Hypertension.

Zelt JGE, Chaudhary KR, Cadete VJ, Mielniczuk LM, Stewart DJ.

Circ Res. 2019 May 24;124(11):1551-1567. doi: 10.1161/CIRCRESAHA.118.313650.

PMID:
31120820
6.

Biomarkers in the Diagnosis, Management, and Prognostication of Perioperative Right Ventricular Failure in Cardiac Surgery-Are We There Yet?

Jabagi H, Mielniczuk LM, Liu PP, Ruel M, Sun LY.

J Clin Med. 2019 Apr 25;8(4). pii: E559. doi: 10.3390/jcm8040559. Review.

7.

Impact of organ prioritization for immunologic sensitization and waiting times for heart transplantation.

Aleksova N, Alba AC, Fan CS, Mueller B, Mielniczuk LM, Davies RA, Stadnick E, Ross HJ, Chih S.

J Heart Lung Transplant. 2019 Mar;38(3):285-294. doi: 10.1016/j.healun.2018.12.016. Epub 2018 Dec 21.

PMID:
30658880
8.

Micro Computed Tomography in Experimental Pulmonary Arterial Hypertension.

Zelt JGE, Mielniczuk LM.

Circ Cardiovasc Imaging. 2018 Dec;11(12):e008631. doi: 10.1161/CIRCIMAGING.118.008631. No abstract available.

PMID:
30562106
9.

Utility of Novel Cardiorenal Biomarkers in the Prediction and Early Detection of Congestive Kidney Injury Following Cardiac Surgery.

Zelt JGE, Mielniczuk LM, Liu PP, Dupuis JY, Chih S, Akbari A, Sun LY.

J Clin Med. 2018 Dec 12;7(12). pii: E540. doi: 10.3390/jcm7120540.

10.

Diffuse Subepicardial Late Gadolinium Enhancement After Heart Transplant: A Potentially Ominous Finding.

Almufleh A, Garuba H, Mielniczuk LM, Davies RA, Stadnick E, Belanger E, Dick A, Kozuszko S, Ross HJ, Chih S.

Can J Cardiol. 2018 Dec;34(12):1687.e3-1687.e7. doi: 10.1016/j.cjca.2018.08.032. Epub 2018 Aug 24.

PMID:
30527162
11.

PET imaging of sympathetic innervation with [18F]Flurobenguan vs [11C]mHED in a patient with ischemic cardiomyopathy.

Zelt JGE, Mielniczuk LM, Orlandi C, Robinson S, Hadizad T, Walter O, Garrard L, Beanlands RSB, deKemp RA.

J Nucl Cardiol. 2019 Dec;26(6):2151-2153. doi: 10.1007/s12350-018-01527-5. Epub 2018 Nov 19. No abstract available.

PMID:
30456496
12.

Effects of Riociguat on Right Ventricular Remodelling in Chronic Thromboembolic Pulmonary Hypertension Patients: A Prospective Study.

Ahmadi A, Thornhill RE, Pena E, Renaud JM, Promislow S, Chandy G, Davies RA, Stewart DJ, Contreras-Dominguez V, Dunne R, Doyle-Cox C, Beanlands RS, deKemp RA, Mielniczuk LM.

Can J Cardiol. 2018 Sep;34(9):1137-1144. doi: 10.1016/j.cjca.2018.06.007. Epub 2018 Jun 25.

PMID:
30170668
13.

Sex-Specific Trends in Incidence and Mortality for Urban and Rural Ambulatory Patients with Heart Failure in Eastern Ontario from 1994 to 2013.

Sun LY, Tu JV, Sherrard H, Rodger N, Coutinho T, Turek M, Chan E, Tulloch H, McDonnell L, Mielniczuk LM.

J Card Fail. 2018 Sep;24(9):568-574. doi: 10.1016/j.cardfail.2018.07.465. Epub 2018 Aug 10.

PMID:
30099191
14.

Sex differences in outcomes of heart failure in an ambulatory, population-based cohort from 2009 to 2013.

Sun LY, Tu JV, Coutinho T, Turek M, Rubens FD, McDonnell L, Tulloch H, Eddeen AB, Mielniczuk LM.

CMAJ. 2018 Jul 16;190(28):E848-E854. doi: 10.1503/cmaj.180177.

15.

Coronary artery microvascular dysfunction: Role of sex and arterial load.

Coutinho T, Mielniczuk LM, Srivaratharajah K, deKemp R, Wells GA, Beanlands RS.

Int J Cardiol. 2018 Nov 1;270:42-47. doi: 10.1016/j.ijcard.2018.06.072. Epub 2018 Jun 20.

PMID:
29954671
16.

Reply to Kawada-N-Terminal Pro B-Type Natriuretic Peptide, High-Sensitivity Cardiac Troponin T and the Extent of Hibernating Myocardium.

Zelt JGE, Wells G, Mielniczuk LM, Beanlands RS.

Can J Cardiol. 2018 May;34(5):690.e13. doi: 10.1016/j.cjca.2018.01.085. Epub 2018 Feb 1. No abstract available.

PMID:
29731030
17.

PET Assessment of Epicardial Intimal Disease and Microvascular Dysfunction in Cardiac Allograft Vasculopathy.

Chih S, Chong AY, Erthal F, deKemp RA, Davies RA, Stadnick E, So DY, Overgaard C, Wells G, Mielniczuk LM, Beanlands RSB.

J Am Coll Cardiol. 2018 Apr 3;71(13):1444-1456. doi: 10.1016/j.jacc.2018.01.062.

18.

Repeatable and reproducible measurements of myocardial oxidative metabolism, blood flow and external efficiency using 11C-acetate PET.

Wu KY, Dinculescu V, Renaud JM, Chen SY, Burwash IG, Mielniczuk LM, Beanlands RSB, deKemp RA.

J Nucl Cardiol. 2018 Dec;25(6):1912-1925. doi: 10.1007/s12350-018-1206-y. Epub 2018 Feb 16.

PMID:
29453603
19.

Profound Vasoplegia During Sacubitril/Valsartan Treatment After Heart Transplantation.

Almufleh A, Mielniczuk LM, Zinoviev R, Moeller A, Davies RA, Stadnick E, Chan V, Chih S.

Can J Cardiol. 2018 Mar;34(3):343.e5-343.e7. doi: 10.1016/j.cjca.2017.12.004. Epub 2017 Dec 11.

PMID:
29398176
20.

N-Terminal Pro B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin T Levels Are Related to the Extent of Hibernating Myocardium in Patients With Ischemic Heart Failure.

Zelt JGE, Liu PP, Erthal F, deKemp RA, Wells G, O'Meara E, Garrard L, Beanlands RSB, Mielniczuk LM.

Can J Cardiol. 2017 Nov;33(11):1478-1488. doi: 10.1016/j.cjca.2017.06.012. Epub 2017 Jun 27.

PMID:
28966019
21.

Cardiac Amyloidosis Phenotype Associated With a Glu89Lys Transthyretin Mutation.

Bourque PR, McCurdy AR, Mielniczuk LM, Dennie C, Veinot JP, Warman Chardon J.

Can J Cardiol. 2017 Jun;33(6):830.e5-830.e7. doi: 10.1016/j.cjca.2017.01.023. Epub 2017 Feb 3.

PMID:
28395866
22.

Can Functional Testing for Ischemia and Viability Guide Revascularization?

Mielniczuk LM, Toth GG, Xie JX, De Bruyne B, Shaw LJ, Beanlands RS.

JACC Cardiovasc Imaging. 2017 Mar;10(3):354-364. doi: 10.1016/j.jcmg.2016.12.011. Review.

23.

Effects of an endothelin receptor antagonist, Macitentan, on right ventricular substrate utilization and function in a Sugen 5416/hypoxia rat model of severe pulmonary arterial hypertension.

Drozd K, Ahmadi A, Deng Y, Jiang B, Petryk J, Thorn S, Stewart D, Beanlands R, deKemp RA, DaSilva JN, Mielniczuk LM.

J Nucl Cardiol. 2017 Dec;24(6):1979-1989. doi: 10.1007/s12350-016-0663-4. Epub 2016 Sep 29.

PMID:
27688036
24.

Reduced Myocardial Flow in Heart Failure Patients With Preserved Ejection Fraction.

Srivaratharajah K, Coutinho T, deKemp R, Liu P, Haddad H, Stadnick E, Davies RA, Chih S, Dwivedi G, Guo A, Wells GA, Bernick J, Beanlands R, Mielniczuk LM.

Circ Heart Fail. 2016 Jul;9(7). pii: e002562. doi: 10.1161/CIRCHEARTFAILURE.115.002562.

PMID:
27413034
25.

Allograft Vasculopathy: The Achilles' Heel of Heart Transplantation.

Chih S, Chong AY, Mielniczuk LM, Bhatt DL, Beanlands RS.

J Am Coll Cardiol. 2016 Jul 5;68(1):80-91. doi: 10.1016/j.jacc.2016.04.033. Review.

26.

Psychosocial Burdens of Pulmonary Arterial Hypertension: A Discussion Paper.

Doyle-Cox C, Brousseau C, Tulloch H, Mielniczuk LM, Davies RA, Sherrard H, Clark L.

Can J Cardiovasc Nurs. 2016 Winter;26(1):14-8. Review.

PMID:
27159936
27.

Reversible pulmonary arterial hypertension associated with interferon-beta treatment for multiple sclerosis.

Gibbons E, Promislow S, Davies RA, Chandy G, Stewart DJ, Vladamir CD, Pugliese C, Dunne R, Mielniczuk LM.

Can Respir J. 2015 Sep-Oct;22(5):263-5. Epub 2015 Jun 17.

28.

Shifts in myocardial fatty acid and glucose metabolism in pulmonary arterial hypertension: a potential mechanism for a maladaptive right ventricular response.

Ohira H, deKemp R, Pena E, Davies RA, Stewart DJ, Chandy G, Contreras-Dominguez V, Dennie C, Mc Ardle B, Mc Klein R, Renaud JM, DaSilva JN, Pugliese C, Dunne R, Beanlands R, Mielniczuk LM.

Eur Heart J Cardiovasc Imaging. 2016 Dec;17(12):1424-1431. doi: 10.1093/ehjci/jev136. Epub 2015 Jun 9.

PMID:
26060207
29.

An evidence-based approach to screening and diagnosis of pulmonary hypertension.

Haddad RN, Mielniczuk LM.

Can J Cardiol. 2015 Apr;31(4):382-90. doi: 10.1016/j.cjca.2015.01.018. Epub 2015 Jan 28. Review.

PMID:
25840091
30.

FDG PET imaging for identifying pulmonary hypertension and right heart failure.

Ahmadi A, Ohira H, Mielniczuk LM.

Curr Cardiol Rep. 2015 Jan;17(1):555. doi: 10.1007/s11886-014-0555-7. Review.

PMID:
25504422
31.

Prognostic value of rubidium-82 positron emission tomography in patients after heart transplant.

Mc Ardle BA, Davies RA, Chen L, Small GR, Ruddy TD, Dwivedi G, Yam Y, Haddad H, Mielniczuk LM, Stadnick E, Hessian R, Guo A, Beanlands RS, deKemp RA, Chow BJ.

Circ Cardiovasc Imaging. 2014 Nov;7(6):930-7. doi: 10.1161/CIRCIMAGING.114.002184. Epub 2014 Sep 2.

PMID:
25182366
32.

Riociguat: a novel therapeutic option for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

Mielniczuk LM, Swiston JR, Mehta S.

Can J Cardiol. 2014 Oct;30(10):1233-40. doi: 10.1016/j.cjca.2014.04.014. Epub 2014 Apr 18. Review.

PMID:
25154043
33.

Effects of short-term continuous positive airway pressure on myocardial sympathetic nerve function and energetics in patients with heart failure and obstructive sleep apnea: a randomized study.

Hall AB, Ziadi MC, Leech JA, Chen SY, Burwash IG, Renaud J, deKemp RA, Haddad H, Mielniczuk LM, Yoshinaga K, Guo A, Chen L, Walter O, Garrard L, DaSilva JN, Floras JS, Beanlands RS.

Circulation. 2014 Sep 9;130(11):892-901. doi: 10.1161/CIRCULATIONAHA.113.005893. Epub 2014 Jul 3.

PMID:
24993098
34.

Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B).

Paterson I, Wells GA, Ezekowitz JA, White JA, Friedrich MG, Mielniczuk LM, O'Meara E, Chow B, DeKemp RA, Klein R, Dennie C, Dick A, Coyle D, Dwivedi G, Rajda M, Wright GA, Laine M, Hanninen H, Larose E, Connelly KA, Leong-Poi H, Howarth AG, Davies RA, Duchesne L, Yla-Herttuala S, Saraste A, Farand P, Garrard L, Tardif JC, Arnold M, Knuuti J, Beanlands R, Chan KL.

Trials. 2013 Oct 12;14:332. doi: 10.1186/1745-6215-14-332.

35.

Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial.

O'Meara E, Mielniczuk LM, Wells GA, deKemp RA, Klein R, Coyle D, Mc Ardle B, Paterson I, White JA, Arnold M, Friedrich MG, Larose E, Dick A, Chow B, Dennie C, Haddad H, Ruddy T, Ukkonen H, Wisenberg G, Cantin B, Pibarot P, Freeman M, Turcotte E, Connelly K, Clarke J, Williams K, Racine N, Garrard L, Tardif JC, DaSilva J, Knuuti J, Beanlands R; IMAGE HF investigators.

Trials. 2013 Jul 16;14:218. doi: 10.1186/1745-6215-14-218.

36.

Sudden power loss in a HeartMate II left ventricular assist device due to intermittent pin contact with the battery: case report.

Belway D, Cleland M, Zakutney T, Grenon J, Mielniczuk LM, Hendry PJ.

ASAIO J. 2013 May-Jun;59(3):317-9. doi: 10.1097/MAT.0b013e318288a3a8.

PMID:
23644621
37.

Giant cell myocarditis in a patient with a spondyloarthropathy after a drug hypersensitivity reaction.

Mitoff PR, Mesana TG, Mielniczuk LM, Grenon J, Veinot JP, Cooper LT Jr, Davies RA.

Can J Cardiol. 2013 Sep;29(9):1138.e7-8. doi: 10.1016/j.cjca.2012.12.011. Epub 2013 Mar 6.

PMID:
23474137
38.

Imaging heart failure: current and future applications.

Paterson I, Mielniczuk LM, O'Meara E, So A, White JA.

Can J Cardiol. 2013 Mar;29(3):317-28. doi: 10.1016/j.cjca.2013.01.006. Review.

PMID:
23439018
39.

Worsening renal function and prognosis in pulmonary hypertension patients hospitalized for right heart failure.

Mielniczuk LM, Chandy G, Stewart D, Contreras-Dominguez V, Haddad H, Pugliese C, Davies RA.

Congest Heart Fail. 2012 May-Jun;18(3):151-7. doi: 10.1111/j.1751-7133.2011.00275.x. Epub 2012 Jan 23.

41.

Usefulness of beta-blocker therapy and outcomes in patients with pulmonary arterial hypertension.

So PP, Davies RA, Chandy G, Stewart D, Beanlands RS, Haddad H, Pugliese C, Mielniczuk LM.

Am J Cardiol. 2012 May 15;109(10):1504-9. doi: 10.1016/j.amjcard.2012.01.368. Epub 2012 Mar 3.

PMID:
22385756
42.

Dual therapy in IPAH and SSc-PAH. A qualitative systematic review.

Johnson SR, Brode SK, Mielniczuk LM, Granton JT.

Respir Med. 2012 May;106(5):730-9. doi: 10.1016/j.rmed.2011.12.018. Epub 2012 Feb 25. Review.

43.

Imaging the failing right ventricle.

Mitoff PR, Beauchesne L, Dick AJ, Chow BJ, Beanlands RS, Haddad H, Mielniczuk LM.

Curr Opin Cardiol. 2012 Mar;27(2):148-53. doi: 10.1097/HCO.0b013e32834fec4e. Review.

PMID:
22314299
44.

Relation between right ventricular function and increased right ventricular [18F]fluorodeoxyglucose accumulation in patients with heart failure.

Mielniczuk LM, Birnie D, Ziadi MC, deKemp RA, DaSilva JN, Burwash I, Tang AT, Davies RA, Haddad H, Guo A, Aung M, Williams K, Ukkonen H, Beanlands RS.

Circ Cardiovasc Imaging. 2011 Jan;4(1):59-66. doi: 10.1161/CIRCIMAGING.109.905984. Epub 2010 Nov 5.

PMID:
21057116
45.

Ultrafiltration in the management of acute decompensated heart failure.

Mielniczuk LM, Haddad H, Davies RA.

Curr Opin Cardiol. 2010 Mar;25(2):155-60. doi: 10.1097/HCO.0b013e3283358a2b. Review.

PMID:
19996964
46.

Acute decline in renal function, inflammation, and cardiovascular risk after an acute coronary syndrome.

Mielniczuk LM, Pfeffer MA, Lewis EF, Blazing MA, de Lemos JA, Mohanavelu S, Rouleau J, Fox K, Pedersen TR, Califf RM.

Clin J Am Soc Nephrol. 2009 Nov;4(11):1811-7. doi: 10.2215/CJN.03510509. Epub 2009 Oct 9.

47.

The association between high-dose diuretics and clinical stability in ambulatory chronic heart failure patients.

Mielniczuk LM, Tsang SW, Desai AS, Nohria A, Lewis EF, Fang JC, Baughman KL, Stevenson LW, Givertz MM.

J Card Fail. 2008 Jun;14(5):388-93. doi: 10.1016/j.cardfail.2008.01.015. Epub 2008 May 27.

PMID:
18514930
48.

Estimated glomerular filtration rate, inflammation, and cardiovascular events after an acute coronary syndrome.

Mielniczuk LM, Pfeffer MA, Lewis EF, Blazing MA, de Lemos JA, Shui A, Mohanavelu S, Califf RM, Braunwald E.

Am Heart J. 2008 Apr;155(4):725-31. doi: 10.1016/j.ahj.2007.11.031. Epub 2008 Feb 21.

PMID:
18371483
49.

Left ventricular end-diastolic pressure and risk of subsequent heart failure in patients following an acute myocardial infarction.

Mielniczuk LM, Lamas GA, Flaker GC, Mitchell G, Smith SC, Gersh BJ, Solomon SD, Moyé LA, Rouleau JL, Rutherford JD, Pfeffer MA.

Congest Heart Fail. 2007 Jul-Aug;13(4):209-14.

50.

The use of noninvasive ventilation in emergency department patients with acute cardiogenic pulmonary edema: a systematic review.

Collins SP, Mielniczuk LM, Whittingham HA, Boseley ME, Schramm DR, Storrow AB.

Ann Emerg Med. 2006 Sep;48(3):260-9, 269.e1-4. Epub 2006 Apr 25. Review.

PMID:
16934647

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