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Items: 1 to 50 of 85

1.

Secular Trends in Information Communications Technology: Access, Use, and Attitudes of Young and Older Patients With Diabetes.

Middleton TL, Constantino MI, Molyneaux L, AlMogbel T, McGill M, Yue DK, Twigg SM, Wu T, Wong J.

Diabetes Spectr. 2020 Feb;33(1):66-73. doi: 10.2337/ds18-0082.

PMID:
32116456
2.

Young-onset type 2 diabetes and younger current age: increased susceptibility to retinopathy in contrast to other complications.

Middleton TL, Constantino MI, Molyneaux L, D'Souza M, Twigg SM, Wu T, Yue DK, Zoungas S, Wong J.

Diabet Med. 2020 Jan 22. doi: 10.1111/dme.14238. [Epub ahead of print]

PMID:
31968129
3.

A pilot investigation of universal school-based prevention programs for anxiety and depression symptomology in children: A randomized controlled trial.

Johnstone KM, Middleton T, Kemps E, Chen J.

J Clin Psychol. 2020 Jan 13. doi: 10.1002/jclp.22926. [Epub ahead of print]

PMID:
31943189
4.

Maternal vs paternal diabetes: The parental history is different in younger onset versus older onset type 2 diabetes.

Middleton TL, Brooks BA, Constantino MI, Wu T, Wong J, Yue DK.

J Diabetes Complications. 2019 Dec;33(12):107440. doi: 10.1016/j.jdiacomp.2019.107440. Epub 2019 Sep 12.

PMID:
31676253
5.

Pharmacologic therapies for the management of non-neurogenic urinary incontinence in children.

Middleton T, Ellsworth P.

Expert Opin Pharmacother. 2019 Dec;20(18):2335-2352. doi: 10.1080/14656566.2019.1674282. Epub 2019 Oct 23. Review.

PMID:
31644331
6.

Environmental heterogeneity generates intrapopulation variation in life-history traits in an annual plant.

Friedman J, Middleton TE, Rubin MJ.

New Phytol. 2019 Nov;224(3):1171-1183. doi: 10.1111/nph.16099. Epub 2019 Sep 6.

PMID:
31400159
7.

Cannabinoids Modulate Light Signaling in ON-Sustained Retinal Ganglion Cells of the Mouse.

Middleton TP, Huang JY, Protti DA.

Front Neural Circuits. 2019 May 21;13:37. doi: 10.3389/fncir.2019.00037. eCollection 2019.

8.

Evidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer's disease.

Youssef P, Chami B, Lim J, Middleton T, Sutherland GT, Witting PK.

Sci Rep. 2018 Aug 1;8(1):11553. doi: 10.1038/s41598-018-29770-3.

9.

The Landscape of Diabetic Kidney Disease in the United States.

Duru OK, Middleton T, Tewari MK, Norris K.

Curr Diab Rep. 2018 Feb 19;18(3):14. doi: 10.1007/s11892-018-0980-x. Review.

10.

In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir.

Ng TI, Tripathi R, Reisch T, Lu L, Middleton T, Hopkins TA, Pithawalla R, Irvin M, Dekhtyar T, Krishnan P, Schnell G, Beyer J, McDaniel KF, Ma J, Wang G, Jiang LJ, Or YS, Kempf D, Pilot-Matias T, Collins C.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01620-17. doi: 10.1128/AAC.01620-17. Print 2018 Jan.

11.

Efficacy of feed additives to reduce the effect of naturally occurring mycotoxins fed to turkey hen poults reared to 6 weeks of age.

Tilley JEN, Grimes JL, Koci MD, Ali RA, Stark CR, Nighot PK, Middleton TF, Fahrenholz AC.

Poult Sci. 2017 Dec 1;96(12):4236-4244. doi: 10.3382/ps/pex214.

12.

Assessment of an irritant gas plume model for epidemiologic study.

Jani DD, Wilson M, Wickliffe JK, Shaffer J, Middleton T, Rando R, Svendsen ER.

Int J Environ Health Res. 2017 Aug;27(4):276-292. doi: 10.1080/09603123.2017.1342226. Epub 2017 Jun 29.

13.

Genetic and environmental integration of the hawkmoth pollination syndrome in Ruellia humilis (Acanthaceae).

Heywood JS, Michalski JS, McCann BK, Russo AD, Andres KJ, Hall AR, Middleton TC.

Ann Bot. 2017 May 1;119(7):1143-1155. doi: 10.1093/aob/mcx003.

14.

Cardiac Effects of Sulfonylurea-Related Hypoglycemia.

Middleton TL, Wong J, Molyneaux L, Brooks BA, Yue DK, Twigg SM, Wu T.

Diabetes Care. 2017 May;40(5):663-670. doi: 10.2337/dc16-1972. Epub 2017 Feb 21.

PMID:
28223296
15.

An unusual presentation of X-linked adrenoleukodystrophy.

Suryawanshi A, Middleton T, Ganda K.

Endocrinol Diabetes Metab Case Rep. 2015;2015:150098. doi: 10.1530/EDM-15-0098. Epub 2015 Nov 3.

16.

A unique blue spot.

Middleton T, Dritsoula A, Thevasagayam M.

Int J Pediatr Otorhinolaryngol. 2015 Sep;79(9):1571-2. doi: 10.1016/j.ijporl.2015.05.014. Epub 2015 May 27.

PMID:
26211389
17.

Complications of injectable testosterone undecanoate in routine clinical practice.

Middleton T, Turner L, Fennell C, Savkovic S, Jayadev V, Conway AJ, Handelsman DJ.

Eur J Endocrinol. 2015 May;172(5):511-7. doi: 10.1530/EJE-14-0891. Epub 2015 Jan 30.

PMID:
25637074
18.

In vitro and in vivo antiviral activity and resistance profile of the hepatitis C virus NS3/4A protease inhibitor ABT-450.

Pilot-Matias T, Tripathi R, Cohen D, Gaultier I, Dekhtyar T, Lu L, Reisch T, Irvin M, Hopkins T, Pithawalla R, Middleton T, Ng T, McDaniel K, Or YS, Menon R, Kempf D, Molla A, Collins C.

Antimicrob Agents Chemother. 2015 Feb;59(2):988-97. doi: 10.1128/AAC.04227-14. Epub 2014 Dec 1.

19.

C-reactive protein as a predictor of cardiovascular risk in HIV-infected individuals.

Westhorpe CL, Schneider HG, Dunne M, Middleton T, Sundararajan V, Spelman T, Carter V, Crowe SM, Dart A, Mijch A, Kotsanas D, Woolley I.

Sex Health. 2014 Dec;11(6):580-2. doi: 10.1071/SH14130.

PMID:
25435195
20.

25th Anniversary Supplement of the Journal of Health Care for the Poor and Underserved.

Baquet CR, Middleton TM.

J Health Care Poor Underserved. 2014 Feb;25(1 Suppl):x-xiv. doi: 10.1353/hpu.2014.0068. No abstract available.

21.

Mammary Paget disease.

Burke MJ, Middleton TO.

J Am Osteopath Assoc. 2013 Sep;113(9):712. doi: 10.7556/jaoa.2013.038. No abstract available.

PMID:
24005092
22.

The use of feed additives to reduce the effects of aflatoxin and deoxynivalenol on pig growth, organ health and immune status during chronic exposure.

Weaver AC, See MT, Hansen JA, Kim YB, De Souza AL, Middleton TF, Kim SW.

Toxins (Basel). 2013 Jul 17;5(7):1261-81. doi: 10.3390/toxins5071261.

23.

Acceptability of home use of mifepristone for medical abortion.

Swica Y, Chong E, Middleton T, Prine L, Gold M, Schreiber CA, Winikoff B.

Contraception. 2013 Jul;88(1):122-7. doi: 10.1016/j.contraception.2012.10.021. Epub 2012 Nov 21.

PMID:
23177917
24.

Image-guided prostate biopsy using magnetic resonance imaging-derived targets: a systematic review.

Moore CM, Robertson NL, Arsanious N, Middleton T, Villers A, Klotz L, Taneja SS, Emberton M.

Eur Urol. 2013 Jan;63(1):125-40. doi: 10.1016/j.eururo.2012.06.004. Epub 2012 Jun 13. Review.

PMID:
22743165
25.

Viral gastroenteritis associated with genogroup II norovirus among U.S. military personnel in Turkey, 2009.

Ahmed SF, Klena JD, Mostafa M, Dogantemur J, Middleton T, Hanson J, Sebeny PJ.

PLoS One. 2012;7(5):e35791. doi: 10.1371/journal.pone.0035791. Epub 2012 May 11.

26.

Cannabinoids modulate spontaneous synaptic activity in retinal ganglion cells.

Middleton TP, Protti DA.

Vis Neurosci. 2011 Sep;28(5):393-402. doi: 10.1017/S0952523811000198. Epub 2011 Jul 12.

PMID:
21745438
27.

Hepatitis C NS5B polymerase inhibitors: functional equivalents for the benzothiadiazine moiety.

Hutchinson DK, Flentge CA, Donner PL, Wagner R, Maring CJ, Kati WM, Liu Y, Masse SV, Middleton T, Mo H, Montgomery D, Jiang WW, Koev G, Beno DW, Stewart KD, Stoll VS, Molla A, Kempf DJ.

Bioorg Med Chem Lett. 2011 Mar 15;21(6):1876-9. doi: 10.1016/j.bmcl.2010.12.067. Epub 2011 Jan 13.

PMID:
21316235
28.

Effects of chronic exposure of diets with reduced concentrations of aflatoxin and deoxynivalenol on growth and immune status of pigs.

Chaytor AC, See MT, Hansen JA, de Souza AL, Middleton TF, Kim SW.

J Anim Sci. 2011 Jan;89(1):124-35. doi: 10.2527/jas.2010-3005. Epub 2010 Oct 1.

PMID:
20889686
29.
30.

Alternative methods for disposal of spent laying hens: evaluation of the efficacy of grinding, mechanical deboning, and of keratinase in the rendering process.

Freeman SR, Poore MH, Middleton TF, Ferket PR.

Bioresour Technol. 2009 Oct;100(19):4515-20. doi: 10.1016/j.biortech.2009.01.077. Epub 2009 May 15.

PMID:
19447033
31.

Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazines.

Wagner R, Larson DP, Beno DW, Bosse TD, Darbyshire JF, Gao Y, Gates BD, He W, Henry RF, Hernandez LE, Hutchinson DK, Jiang WW, Kati WM, Klein LL, Koev G, Kohlbrenner W, Krueger AC, Liu J, Liu Y, Long MA, Maring CJ, Masse SV, Middleton T, Montgomery DA, Pratt JK, Stuart P, Molla A, Kempf DJ.

J Med Chem. 2009 Mar 26;52(6):1659-69. doi: 10.1021/jm8010965.

PMID:
19226162
32.

Determination of nitrogen balance in goats fed a meal produced from hydrolyzed spent hen hard tissues.

Freeman SR, Poore MH, Huntington GB, Middleton TF, Ferket PR.

J Anim Sci. 2009 Mar;87(3):1068-76. doi: 10.2527/jas.2008-1077. Epub 2008 Nov 7.

PMID:
18997067
33.

Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives.

Hutchinson DK, Rosenberg T, Klein LL, Bosse TD, Larson DP, He W, Jiang WW, Kati WM, Kohlbrenner WE, Liu Y, Masse SV, Middleton T, Molla A, Montgomery DA, Beno DW, Stewart KD, Stoll VS, Kempf DJ.

Bioorg Med Chem Lett. 2008 Jul 15;18(14):3887-90. doi: 10.1016/j.bmcl.2008.06.043. Epub 2008 Jun 18.

PMID:
18599294
34.

Evaluation of secondary protein nutrients as a substitute for soybean meal in diets for beef steers and meat goats.

Freeman SR, Poore MH, Huntington GB, Middleton TF.

J Anim Sci. 2008 Jan;86(1):146-58.

PMID:
18086869
35.

Relative replication capacity and selective advantage profiles of protease inhibitor-resistant hepatitis C virus (HCV) NS3 protease mutants in the HCV genotype 1b replicon system.

He Y, King MS, Kempf DJ, Lu L, Lim HB, Krishnan P, Kati W, Middleton T, Molla A.

Antimicrob Agents Chemother. 2008 Mar;52(3):1101-10. Epub 2007 Dec 17.

36.

Synthesis and SAR of novel 1,1-dialkyl-2(1H)-naphthalenones as potent HCV polymerase inhibitors.

Bosse TD, Larson DP, Wagner R, Hutchinson DK, Rockway TW, Kati WM, Liu Y, Masse S, Middleton T, Mo H, Montgomery D, Jiang W, Koev G, Kempf DJ, Molla A.

Bioorg Med Chem Lett. 2008 Jan 15;18(2):568-70. Epub 2007 Nov 28.

PMID:
18068361
37.

Activity of a potent hepatitis C virus polymerase inhibitor in the chimpanzee model.

Chen CM, He Y, Lu L, Lim HB, Tripathi RL, Middleton T, Hernandez LE, Beno DW, Long MA, Kati WM, Bosse TD, Larson DP, Wagner R, Lanford RE, Kohlbrenner WE, Kempf DJ, Pilot-Matias TJ, Molla A.

Antimicrob Agents Chemother. 2007 Dec;51(12):4290-6. Epub 2007 Oct 1.

38.

Longer wavelength fluorescence resonance energy transfer depsipeptide substrates for hepatitis C virus NS3 protease.

Konstantinidis AK, Richardson PL, Kurtz KA, Tripathi R, Chen CM, Huang P, Randolph J, Towne D, Donnelly J, Warrior U, Middleton T, Kati WM.

Anal Biochem. 2007 Sep 15;368(2):156-67. Epub 2007 Jun 17.

PMID:
17644059
39.

A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations.

Middleton T, He Y, Pilot-Matias T, Tripathi R, Lim BH, Roth A, Chen CM, Koev G, Ng TI, Krishnan P, Pithawalla R, Mondal R, Dekhtyar T, Lu L, Mo H, Kati WM, Molla A.

J Virol Methods. 2007 Nov;145(2):137-45. Epub 2007 Jun 29.

PMID:
17604129
40.

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of unsymmetrical 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives.

Krueger AC, Madigan DL, Green BE, Hutchinson DK, Jiang WW, Kati WM, Liu Y, Maring CJ, Masse SV, McDaniel KF, Middleton TR, Mo H, Molla A, Montgomery DA, Ng TI, Kempf DJ.

Bioorg Med Chem Lett. 2007 Apr 15;17(8):2289-92. Epub 2007 Jan 27.

PMID:
17300933
41.

Fair Share Health Care.

Middleton T.

Md Med. 2006 Autumn;7(3):10-1. No abstract available.

PMID:
17112124
42.

Replication efficiency of chimeric replicon containing NS5A-5B genes derived from HCV-infected patient sera.

Tripathi RL, Krishnan P, He Y, Middleton T, Pilot-Matias T, Chen CM, Lau DT, Lemon SM, Mo H, Kati W, Molla A.

Antiviral Res. 2007 Jan;73(1):40-9. Epub 2006 Jul 28.

PMID:
16914212
43.

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-benzyl and N-1-[3-methylbutyl]-4-hydroxy-1,8-naphthyridon-3-yl benzothiadiazine analogs containing substituents on the aromatic ring.

Rockway TW, Zhang R, Liu D, Betebenner DA, McDaniel KF, Pratt JK, Beno D, Montgomery D, Jiang WW, Masse S, Kati WM, Middleton T, Molla A, Maring CJ, Kempf DJ.

Bioorg Med Chem Lett. 2006 Jul 15;16(14):3833-8. Epub 2006 May 2.

PMID:
16650984
44.

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides.

Krueger AC, Madigan DL, Jiang WW, Kati WM, Liu D, Liu Y, Maring CJ, Masse S, McDaniel KF, Middleton T, Mo H, Molla A, Montgomery D, Pratt JK, Rockway TW, Zhang R, Kempf DJ.

Bioorg Med Chem Lett. 2006 Jul 1;16(13):3367-70. Epub 2006 May 2.

PMID:
16650764
45.

Randomized trial of mifepristone and buccal or vaginal misoprostol for abortion through 56 days of last menstrual period.

Middleton T, Schaff E, Fielding SL, Scahill M, Shannon C, Westheimer E, Wilkinson T, Winikoff B.

Contraception. 2005 Nov;72(5):328-32. Epub 2005 Aug 9.

PMID:
16246656
46.

Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines.

Pratt JK, Donner P, McDaniel KF, Maring CJ, Kati WM, Mo H, Middleton T, Liu Y, Ng T, Xie Q, Zhang R, Montgomery D, Molla A, Kempf DJ, Kohlbrenner W.

Bioorg Med Chem Lett. 2005 Mar 15;15(6):1577-82.

PMID:
15745800
47.

The molecular epidemiology of HIV type 1 among Vietnamese Australian injecting drug users in Melbourne, Australia.

Ryan CE, Elliott JH, Middleton T, Mijch AM, Street AC, Hellard M, Crofts N, Crowe SM, Oelrichs RB.

AIDS Res Hum Retroviruses. 2004 Dec;20(12):1364-7.

PMID:
15650430
48.

Inhibition of human immunodeficiency virus type I integrase by naphthamidines and 2-aminobenzimidazoles.

Middleton T, Lim HB, Montgomery D, Rockway T, Tang H, Cheng X, Lu L, Mo H, Kohlbrenner WE, Molla A, Kati WM.

Antiviral Res. 2004 Oct;64(1):35-45.

PMID:
15451177
49.
50.

Use of SAM2 biotin capture membrane in microarrayed compound screening (muARCS) format for nucleic acid polymerization assays.

Xuei X, David CA, Middleton TR, Lim B, Pithawalla R, Chen CM, Tripathi RL, Burns DJ, Warrior U.

J Biomol Screen. 2003 Jun;8(3):273-82.

PMID:
12857381

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