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Items: 1 to 50 of 178

1.

The oral microbiome of early stage Parkinson's disease and its relationship with functional measures of motor and non-motor function.

Mihaila D, Donegan J, Barns S, LaRocca D, Du Q, Zheng D, Vidal M, Neville C, Uhlig R, Middleton FA.

PLoS One. 2019 Jun 27;14(6):e0218252. doi: 10.1371/journal.pone.0218252. eCollection 2019.

2.

An Adaptive Multivariate Two-Sample Test With Application to Microbiome Differential Abundance Analysis.

Banerjee K, Zhao N, Srinivasan A, Xue L, Hicks SD, Middleton FA, Wu R, Zhan X.

Front Genet. 2019 Apr 24;10:350. doi: 10.3389/fgene.2019.00350. eCollection 2019.

3.

Saliva MicroRNA Differentiates Children With Autism From Peers With Typical and Atypical Development.

Hicks SD, Carpenter RL, Wagner KE, Pauley R, Barros M, Tierney-Aves C, Barns S, Greene CD, Middleton FA.

J Am Acad Child Adolesc Psychiatry. 2020 Feb;59(2):296-308. doi: 10.1016/j.jaac.2019.03.017. Epub 2019 Mar 27.

4.

Parent Perspectives Towards Genetic and Epigenetic Testing for Autism Spectrum Disorder.

Wagner KE, McCormick JB, Barns S, Carney M, Middleton FA, Hicks SD.

J Autism Dev Disord. 2019 Mar 22. doi: 10.1007/s10803-019-03990-6. [Epub ahead of print]

PMID:
30903561
5.

Differential expression of miRNAs in acute myeloid leukemia quantified by Nextgen sequencing of whole blood samples.

Pandita A, Ramadas P, Poudel A, Saad N, Anand A, Basnet A, Wang D, Middleton F, Gilligan DM.

PLoS One. 2019 Mar 20;14(3):e0213078. doi: 10.1371/journal.pone.0213078. eCollection 2019.

6.

Mitochondrial carrier protein overloading and misfolding induce aggresomes and proteostatic adaptations in the cytosol.

Liu Y, Wang X, Coyne LP, Yang Y, Qi Y, Middleton FA, Chen XJ.

Mol Biol Cell. 2019 May 15;30(11):1272-1284. doi: 10.1091/mbc.E19-01-0046. Epub 2019 Mar 20.

7.

Effect of lesion proximity on the regenerative response of long descending propriospinal neurons after spinal transection injury.

Swieck K, Conta-Steencken A, Middleton FA, Siebert JR, Osterhout DJ, Stelzner DJ.

BMC Neurosci. 2019 Mar 18;20(1):10. doi: 10.1186/s12868-019-0491-y.

8.

Comparison of serum and saliva miRNAs for identification and characterization of mTBI in adult mixed martial arts fighters.

LaRocca D, Barns S, Hicks SD, Brindle A, Williams J, Uhlig R, Johnson P, Neville C, Middleton FA.

PLoS One. 2019 Jan 2;14(1):e0207785. doi: 10.1371/journal.pone.0207785. eCollection 2019.

9.

The Transcriptional Signature of a Runner's High.

Hicks SD, Jacob P, Perez O, Baffuto M, Gagnon Z, Middleton FA.

Med Sci Sports Exerc. 2019 May;51(5):970-978. doi: 10.1249/MSS.0000000000001865.

PMID:
30557194
10.

Oxytocin receptor gene (OXTR) links to marital quality via social support behavior and perceived partner responsiveness.

Mattson RE, Cameron N, Middleton FA, Starr LR, Davila J, Johnson MD.

J Fam Psychol. 2019 Feb;33(1):44-53. doi: 10.1037/fam0000474. Epub 2018 Nov 29.

PMID:
30489130
11.

Validation of a Salivary RNA Test for Childhood Autism Spectrum Disorder.

Hicks SD, Rajan AT, Wagner KE, Barns S, Carpenter RL, Middleton FA.

Front Genet. 2018 Nov 9;9:534. doi: 10.3389/fgene.2018.00534. eCollection 2018.

12.

A role for genes in the 'caregiver stress process'?

Wolf DA, Middleton FA.

Transl Psychiatry. 2018 Oct 22;8(1):228. doi: 10.1038/s41398-018-0275-7.

13.

The Impact of p53 Dysfunction in ATR Inhibitor Cytotoxicity and Chemo- and Radiosensitisation.

Middleton FK, Pollard JR, Curtin NJ.

Cancers (Basel). 2018 Aug 20;10(8). pii: E275. doi: 10.3390/cancers10080275.

14.

Oral microbiome activity in children with autism spectrum disorder.

Hicks SD, Uhlig R, Afshari P, Williams J, Chroneos M, Tierney-Aves C, Wagner K, Middleton FA.

Autism Res. 2018 Sep;11(9):1286-1299. doi: 10.1002/aur.1972. Epub 2018 Aug 14.

PMID:
30107083
15.

Diurnal oscillations in human salivary microRNA and microbial transcription: Implications for human health and disease.

Hicks SD, Khurana N, Williams J, Dowd Greene C, Uhlig R, Middleton FA.

PLoS One. 2018 Jul 18;13(7):e0198288. doi: 10.1371/journal.pone.0198288. eCollection 2018.

16.

Distance running alters peripheral microRNAs implicated in metabolism, fluid balance, and myosin regulation in a sex-specific manner.

Hicks SD, Jacob P, Middleton FA, Perez O, Gagnon Z.

Physiol Genomics. 2018 Aug 1;50(8):658-667. doi: 10.1152/physiolgenomics.00035.2018. Epub 2018 Jun 8.

PMID:
29883262
17.

SHIP1 Deficiency in Inflammatory Bowel Disease Is Associated With Severe Crohn's Disease and Peripheral T Cell Reduction.

Fernandes S, Srivastava N, Sudan R, Middleton FA, Shergill AK, Ryan JC, Kerr WG.

Front Immunol. 2018 May 22;9:1100. doi: 10.3389/fimmu.2018.01100. eCollection 2018.

18.

Crizotinib induces apoptosis and gene expression changes in ALK+ anaplastic large cell lymphoma cell lines; brentuximab synergizes and doxorubicin antagonizes.

Hudson S, Wang D, Middleton F, Nevaldine BH, Naous R, Hutchison RE.

Pediatr Blood Cancer. 2018 Aug;65(8):e27094. doi: 10.1002/pbc.27094. Epub 2018 Apr 26.

PMID:
29697184
19.

Reviewer selection biases editorial decisions on manuscripts.

Hausmann L, Schweitzer B, Middleton FA, Schulz JB.

J Neurochem. 2018 Jan 27. doi: 10.1111/jnc.14314. [Epub ahead of print]

20.

Reduced Slc1a1 expression is associated with neuroinflammation and impaired sensorimotor gating and cognitive performance in mice: Implications for schizophrenia.

Afshari P, Yao WD, Middleton FA.

PLoS One. 2017 Sep 8;12(9):e0183854. doi: 10.1371/journal.pone.0183854. eCollection 2017.

21.

Contrast sensitivity to spatial gratings in moderate and dim light conditions in patients with diabetes in the absence of diabetic retinopathy.

Safi S, Rahimi A, Raeesi A, Safi H, Aghazadeh Amiri M, Malek M, Yaseri M, Haeri M, Middleton FA, Solessio E, Ahmadieh H.

BMJ Open Diabetes Res Care. 2017 Aug 8;5(1):e000408. doi: 10.1136/bmjdrc-2017-000408. eCollection 2017.

22.

Analysis of SHIP1 expression and activity in Crohn's disease patients.

Somasundaram R, Fernandes S, Deuring JJ, de Haar C, Kuipers EJ, Vogelaar L, Middleton FA, van der Woude CJ, Peppelenbosch MP, Kerr WG, Fuhler GM.

PLoS One. 2017 Aug 2;12(8):e0182308. doi: 10.1371/journal.pone.0182308. eCollection 2017.

23.

Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder.

Camargo Moreno M, Mooney SM, Middleton FA.

PLoS One. 2017 Jul 19;12(7):e0180873. doi: 10.1371/journal.pone.0180873. eCollection 2017.

24.

The de novo autism spectrum disorder RELN R2290C mutation reduces Reelin secretion and increases protein disulfide isomerase expression.

Lammert DB, Middleton FA, Pan J, Olson EC, Howell BW.

J Neurochem. 2017 Jul;142(1):89-102. doi: 10.1111/jnc.14045. Epub 2017 May 18.

25.

Analysis of Shared Haplotypes amongst Palauans Maps Loci for Psychotic Disorders to 4q28 and 5q23-q31.

Bodea CA, Middleton FA, Melhem NM, Klei L, Song Y, Tiobech J, Marumoto P, Yano V, Faraone SV, Roeder K, Myles-Worsley M, Devlin B, Byerley W.

Mol Neuropsychiatry. 2017 Feb;2(4):173-184. doi: 10.1159/000450726. Epub 2016 Oct 12.

26.

Associations between neurodevelopmental genes, neuroanatomy, and ultra high risk symptoms of psychosis in 22q11.2 deletion syndrome.

Thompson CA, Karelis J, Middleton FA, Gentile K, Coman IL, Radoeva PD, Mehta R, Fremont WP, Antshel KM, Faraone SV, Kates WR.

Am J Med Genet B Neuropsychiatr Genet. 2017 Apr;174(3):295-314. doi: 10.1002/ajmg.b.32515. Epub 2017 Jan 31.

PMID:
28139055
27.

Cortical-amygdala volumetric ratios predict onset of symptoms of psychosis in 22q11.2 deletion syndrome.

Berhanu D, Mattiaccio LM, Antshel KM, Fremont W, Middleton FA, Kates WR.

Psychiatry Res Neuroimaging. 2017 Jan 30;259:10-15. doi: 10.1016/j.pscychresns.2016.11.006. Epub 2016 Nov 25.

28.

A Comparative Review of microRNA Expression Patterns in Autism Spectrum Disorder.

Hicks SD, Middleton FA.

Front Psychiatry. 2016 Nov 4;7:176. eCollection 2016.

29.
30.

Thrombospondin-1 differentially regulates microRNAs in vascular smooth muscle cells.

Maier KG, Ruhle B, Stein JJ, Gentile KL, Middleton FA, Gahtan V.

Mol Cell Biochem. 2016 Jan;412(1-2):111-7. doi: 10.1007/s11010-015-2614-9. Epub 2016 Jan 4.

PMID:
26728995
31.

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.

Middleton FK, Patterson MJ, Elstob CJ, Fordham S, Herriott A, Wade MA, McCormick A, Edmondson R, May FE, Allan JM, Pollard JR, Curtin NJ.

Oncotarget. 2015 Oct 20;6(32):32396-409. doi: 10.18632/oncotarget.6136.

32.

Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancer.

Alsubhi N, Middleton F, Abdel-Fatah TM, Stephens P, Doherty R, Arora A, Moseley PM, Chan SY, Aleskandarany MA, Green AR, Rakha EA, Ellis IO, Martin SG, Curtin NJ, Madhusudan S.

Mol Oncol. 2016 Feb;10(2):213-23. doi: 10.1016/j.molonc.2015.09.009. Epub 2015 Oct 3.

33.

Characterization of a Novel Mutation in SLC1A1 Associated with Schizophrenia.

Afshari P, Myles-Worsley M, Cohen OS, Tiobech J, Faraone SV, Byerley W, Middleton FA.

Mol Neuropsychiatry. 2015 Oct;1(3):125-44. doi: 10.1159/000433599. Epub 2015 Jul 8.

34.

A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples.

Cohen OS, Weickert TW, Hess JL, Paish LM, McCoy SY, Rothmond DA, Galletly C, Liu D, Weinberg DD, Huang XF, Xu Q, Shen Y, Zhang D, Yue W, Yan J, Wang L, Lu T, He L, Shi Y, Xu M, Che R, Tang W, Chen CH, Chang WH, Hwu HG, Liu CM, Liu YL, Wen CC, Fann CS, Chang CC, Kanazawa T, Middleton FA, Duncan TM, Faraone SV, Weickert CS, Tsuang MT, Glatt SJ.

Mol Psychiatry. 2016 Jul;21(7):975-82. doi: 10.1038/mp.2015.137. Epub 2015 Sep 8.

PMID:
26347318
35.

Alterations in serum microRNA in humans with alcohol use disorders impact cell proliferation and cell death pathways and predict structural and functional changes in brain.

Ignacio C, Hicks SD, Burke P, Lewis L, Szombathyne-Meszaros Z, Middleton FA.

BMC Neurosci. 2015 Sep 5;16:55. doi: 10.1186/s12868-015-0195-x.

36.

Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric population.

Simbiri KO, Smith NA, Otieno R, Wohlford EE, Daud II, Odada SP, Middleton F, Rochford R.

PLoS One. 2015 May 1;10(5):e0125420. doi: 10.1371/journal.pone.0125420. eCollection 2015. Erratum in: PLoS One. 2015;10(6):e0130229.

37.

Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer.

Abdel-Fatah TM, Middleton FK, Arora A, Agarwal D, Chen T, Moseley PM, Perry C, Doherty R, Chan S, Green AR, Rakha E, Ball G, Ellis IO, Curtin NJ, Madhusudan S.

Mol Oncol. 2015 Mar;9(3):569-85. doi: 10.1016/j.molonc.2014.10.013. Epub 2014 Nov 6.

38.

Development of pharmacodynamic biomarkers for ATR inhibitors.

Chen T, Middleton FK, Falcon S, Reaper PM, Pollard JR, Curtin NJ.

Mol Oncol. 2015 Feb;9(2):463-72. doi: 10.1016/j.molonc.2014.09.012. Epub 2014 Oct 13.

39.

Association between autism spectrum disorder in individuals with velocardiofacial (22q11.2 deletion) syndrome and PRODH and COMT genotypes.

Radoeva PD, Coman IL, Salazar CA, Gentile KL, Higgins AM, Middleton FA, Antshel KM, Fremont W, Shprintzen RJ, Morrow BE, Kates WR.

Psychiatr Genet. 2014 Dec;24(6):269-72. doi: 10.1097/YPG.0000000000000062.

40.

Effects of Acute Prenatal Exposure to Ethanol on microRNA Expression are Ameliorated by Social Enrichment.

Ignacio C, Mooney SM, Middleton FA.

Front Pediatr. 2014 Sep 24;2:103. doi: 10.3389/fped.2014.00103. eCollection 2014.

41.

White matter microstructural abnormalities of the cingulum bundle in youths with 22q11.2 deletion syndrome: associations with medication, neuropsychological function, and prodromal symptoms of psychosis.

Kates WR, Olszewski AK, Gnirke MH, Kikinis Z, Nelson J, Antshel KM, Fremont W, Radoeva PD, Middleton FA, Shenton ME, Coman IL.

Schizophr Res. 2015 Jan;161(1):76-84. doi: 10.1016/j.schres.2014.07.010. Epub 2014 Jul 25.

42.

Characterizing runs of homozygosity and their impact on risk for psychosis in a population isolate.

Melhem NM, Lu C, Dresbold C, Middleton FA, Klei L, Wood S, Faraone SV, Vinogradov S, Tiobech J, Yano V, Roeder K, Byerley W, Myles-Worsley M, Devlin B.

Am J Med Genet B Neuropsychiatr Genet. 2014 Sep;165B(6):521-30. doi: 10.1002/ajmg.b.32255. Epub 2014 Jul 1.

43.

Mapping QTL conferring resistance in maize to gray leaf spot disease caused by Cercospora zeina.

Berger DK, Carstens M, Korsman JN, Middleton F, Kloppers FJ, Tongoona P, Myburg AA.

BMC Genet. 2014 May 22;15:60. doi: 10.1186/1471-2156-15-60.

44.

Autism-related behavioral phenotypes in an inbred rat substrain.

Zhang-James Y, Yang L, Middleton FA, Yang L, Patak J, Faraone SV.

Behav Brain Res. 2014 Aug 1;269:103-14. doi: 10.1016/j.bbr.2014.04.035. Epub 2014 Apr 26.

45.

White matter abnormalities in 22q11.2 deletion syndrome: preliminary associations with the Nogo-66 receptor gene and symptoms of psychosis.

Perlstein MD, Chohan MR, Coman IL, Antshel KM, Fremont WP, Gnirke MH, Kikinis Z, Middleton FA, Radoeva PD, Shenton ME, Kates WR.

Schizophr Res. 2014 Jan;152(1):117-23. doi: 10.1016/j.schres.2013.11.015. Epub 2013 Dec 8.

46.

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.

Caza TN, Fernandez DR, Talaber G, Oaks Z, Haas M, Madaio MP, Lai ZW, Miklossy G, Singh RR, Chudakov DM, Malorni W, Middleton F, Banki K, Perl A.

Ann Rheum Dis. 2014 Oct;73(10):1888-97. doi: 10.1136/annrheumdis-2013-203794. Epub 2013 Jul 29.

47.

Implementing the National Hip Fracture Database: An audit of care.

Patel NK, Sarraf KM, Joseph S, Lee C, Middleton FR.

Injury. 2013 Dec;44(12):1934-9. doi: 10.1016/j.injury.2013.04.012. Epub 2013 May 13.

PMID:
23680283
48.

Genetic architecture of Wistar-Kyoto rat and spontaneously hypertensive rat substrains from different sources.

Zhang-James Y, Middleton FA, Faraone SV.

Physiol Genomics. 2013 Jul 2;45(13):528-38. doi: 10.1152/physiolgenomics.00002.2013. Epub 2013 May 14.

49.

Deletion at the SLC1A1 glutamate transporter gene co-segregates with schizophrenia and bipolar schizoaffective disorder in a 5-generation family.

Myles-Worsley M, Tiobech J, Browning SR, Korn J, Goodman S, Gentile K, Melhem N, Byerley W, Faraone SV, Middleton FA.

Am J Med Genet B Neuropsychiatr Genet. 2013 Mar;162B(2):87-95. doi: 10.1002/ajmg.b.32125. Epub 2013 Jan 22.

PMID:
23341099
50.

Functional and biochemical characterization of soleus muscle in Down syndrome mice: insight into the muscle dysfunction seen in the human condition.

Cowley PM, Keslacy S, Middleton FA, DeRuisseau LR, Fernhall B, Kanaley JA, DeRuisseau KC.

Am J Physiol Regul Integr Comp Physiol. 2012 Dec 15;303(12):R1251-60. doi: 10.1152/ajpregu.00312.2012. Epub 2012 Oct 31.

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