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Items: 44

1.

An approach to recombinantly produce mature grape polyphenol oxidase.

Li Y, McLarin MA, Middleditch MJ, Morrow SJ, Kilmartin PA, Leung IKH.

Biochimie. 2019 Jul 5;165:40-47. doi: 10.1016/j.biochi.2019.07.002. [Epub ahead of print]

PMID:
31283975
2.

A revised biosynthetic pathway for the cofactor F420 in prokaryotes.

Bashiri G, Antoney J, Jirgis ENM, Shah MV, Ney B, Copp J, Stuteley SM, Sreebhavan S, Palmer B, Middleditch M, Tokuriki N, Greening C, Scott C, Baker EN, Jackson CJ.

Nat Commun. 2019 Apr 5;10(1):1558. doi: 10.1038/s41467-019-09534-x.

3.

TAS-120 Cancer Target Binding: Defining Reactivity and Revealing the First Fibroblast Growth Factor Receptor 1 (FGFR1) Irreversible Structure.

Kalyukina M, Yosaatmadja Y, Middleditch MJ, Patterson AV, Smaill JB, Squire CJ.

ChemMedChem. 2019 Feb 19;14(4):494-500. doi: 10.1002/cmdc.201800719. Epub 2019 Jan 14.

PMID:
30600916
4.

Protein Levels and Microstructural Changes in Localized Regions of Early Cartilage Degeneration Compared with Adjacent Intact Cartilage.

Jacob B, Jüllig M, Middleditch M, Payne L, Broom N, Sarojini V, Thambyah A.

Cartilage. 2018 Nov 28:1947603518809401. doi: 10.1177/1947603518809401. [Epub ahead of print]

PMID:
30486653
5.

Apparent Hyperthyroidism Caused by Biotin-Like Interference from IgM Anti-Streptavidin Antibodies.

Lam L, Bagg W, Smith G, Chiu WW, Middleditch MJ, Lim JC, Kyle CV.

Thyroid. 2018 Aug;28(8):1063-1067. doi: 10.1089/thy.2017.0673. Epub 2018 Jun 29.

PMID:
29808739
6.

The Apoplastic Secretome of Trichoderma virens During Interaction With Maize Roots Shows an Inhibition of Plant Defence and Scavenging Oxidative Stress Secreted Proteins.

Nogueira-Lopez G, Greenwood DR, Middleditch M, Winefield C, Eaton C, Steyaert JM, Mendoza-Mendoza A.

Front Plant Sci. 2018 Apr 5;9:409. doi: 10.3389/fpls.2018.00409. eCollection 2018.

7.

Differentially Regulated Host Proteins Associated with Chronic Rhinosinusitis Are Correlated with the Sinonasal Microbiome.

Biswas K, Wagner Mackenzie B, Waldvogel-Thurlow S, Middleditch M, Jullig M, Zoing M, Taylor MW, Douglas RG.

Front Cell Infect Microbiol. 2017 Dec 6;7:504. doi: 10.3389/fcimb.2017.00504. eCollection 2017.

8.

Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance.

Mountjoy KG, Caron A, Hubbard K, Shome A, Grey AC, Sun B, Bould S, Middleditch M, Pontré B, McGregor A, Harris PWR, Kowalczyk R, Brimble MA, Botha R, Tan KML, Piper SJ, Buchanan C, Lee S, Coll AP, Elmquist JK.

Mol Metab. 2018 Mar;9:207-216. doi: 10.1016/j.molmet.2017.11.008. Epub 2017 Nov 24.

9.

Synthetic peptides designed to modulate adiponectin assembly improve obesity-related metabolic disorders.

Hampe L, Xu C, Harris PWR, Chen J, Liu M, Middleditch M, Radjainia M, Wang Y, Mitra AK.

Br J Pharmacol. 2017 Dec;174(23):4478-4492. doi: 10.1111/bph.14050. Epub 2017 Nov 2.

10.

Increased collagen within the transverse tubules in human heart failure.

Crossman DJ, Shen X, Jüllig M, Munro M, Hou Y, Middleditch M, Shrestha D, Li A, Lal S, Dos Remedios CG, Baddeley D, Ruygrok PN, Soeller C.

Cardiovasc Res. 2017 Jul 1;113(8):879-891. doi: 10.1093/cvr/cvx055.

PMID:
28444133
11.

Plasmin and regulators of plasmin activity control the migratory capacity and adhesion of human T cells and dendritic cells by regulating cleavage of the chemokine CCL21.

Lorenz N, Loef EJ, Kelch ID, Verdon DJ, Black MM, Middleditch MJ, Greenwood DR, Graham ES, Brooks AE, Dunbar PR, Birch NP.

Immunol Cell Biol. 2016 Nov;94(10):955-963. doi: 10.1038/icb.2016.56. Epub 2016 Jun 15.

PMID:
27301418
12.

Modelling atherosclerosis by proteomics: Molecular changes in the ascending aortas of cholesterol-fed rabbits.

Xu J, Jüllig M, Middleditch MJ, Cooper GJ.

Atherosclerosis. 2015 Sep;242(1):268-76. doi: 10.1016/j.atherosclerosis.2015.07.001. Epub 2015 Jul 10.

PMID:
26232167
13.

Diabetes-induced alterations in tissue collagen and carboxymethyllysine in rat kidneys: Association with increased collagen-degrading proteinases and amelioration by Cu(II)-selective chelation.

Brings S, Zhang S, Choong YS, Hogl S, Middleditch M, Kamalov M, Brimble MA, Gong D, Cooper GJ.

Biochim Biophys Acta. 2015 Aug;1852(8):1610-8. doi: 10.1016/j.bbadis.2015.04.014. Epub 2015 Apr 18.

14.

Using mass spectrometry to detect, differentiate, and semiquantitate closely related peptide hormones in complex milieu: measurement of IGF-II and vesiculin.

Lee KL, Middleditch MJ, Williams GM, Brimble MA, Cooper GJ.

Endocrinology. 2015 Mar;156(3):1194-9. doi: 10.1210/en.2014-1593. Epub 2014 Dec 29.

PMID:
25545381
15.

Crystal structure of kiwellin, a major cell-wall protein from kiwifruit.

Hamiaux C, Maddumage R, Middleditch MJ, Prakash R, Brummell DA, Baker EN, Atkinson RG.

J Struct Biol. 2014 Sep;187(3):276-281. doi: 10.1016/j.jsb.2014.07.005. Epub 2014 Aug 2.

PMID:
25093947
16.

Sphingosine-1-phosphate lyase is expressed by CD68+ cells on the parenchymal side of marginal reticular cells in human lymph nodes.

Park SM, Angel CE, McIntosh JD, Brooks AE, Middleditch M, Chen CJ, Ruggiero K, Cebon J, Rod Dunbar P.

Eur J Immunol. 2014 Aug;44(8):2425-36. doi: 10.1002/eji.201344158. Epub 2014 Jun 12.

17.

A slow-forming isopeptide bond in the structure of the major pilin SpaD from Corynebacterium diphtheriae has implications for pilus assembly.

Kang HJ, Paterson NG, Kim CU, Middleditch M, Chang C, Ton-That H, Baker EN.

Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1190-201. doi: 10.1107/S1399004714001400. Epub 2014 Apr 26.

18.

Lower fetuin-A, retinol binding protein 4 and several metabolites after gastric bypass compared to sleeve gastrectomy in patients with type 2 diabetes.

Jüllig M, Yip S, Xu A, Smith G, Middleditch M, Booth M, Babor R, Beban G, Murphy R.

PLoS One. 2014 May 6;9(5):e96489. doi: 10.1371/journal.pone.0096489. eCollection 2014.

19.

Cephazolin and gentamicin are stable in lactate-buffered fresenius peritoneal dialysate for seven days at room temperature.

Singh GK, Wolley MJ, Laycock VC, Voss DM, Middleditch MJ, Marshall MR.

Perit Dial Int. 2014 Mar-Apr;34(2):227-32. doi: 10.3747/pdi.2013.00013. No abstract available.

20.

Plant antimicrobial peptides snakin-1 and snakin-2: chemical synthesis and insights into the disulfide connectivity.

Harris PW, Yang SH, Molina A, López G, Middleditch M, Brimble MA.

Chemistry. 2014 Apr 22;20(17):5102-10. doi: 10.1002/chem.201303207. Epub 2014 Mar 18.

PMID:
24644073
21.

Structural model for covalent adhesion of the Streptococcus pyogenes pilus through a thioester bond.

Linke-Winnebeck C, Paterson NG, Young PG, Middleditch MJ, Greenwood DR, Witte G, Baker EN.

J Biol Chem. 2014 Jan 3;289(1):177-89. doi: 10.1074/jbc.M113.523761. Epub 2013 Nov 12.

22.

Two optimization strategies of multi-stage design in clinical proteomic studies.

Zeng IS, Lumley T, Ruggiero K, Middleditch M, Woon ST, Stewart RA.

Stat Appl Genet Mol Biol. 2013 Mar 13;12(2):263-83. doi: 10.1515/sagmb-2013-0005.

PMID:
23502344
23.

Identification of key residues involved in adrenomedullin binding to the AM1 receptor.

Watkins HA, Au M, Bobby R, Archbold JK, Abdul-Manan N, Moore JM, Middleditch MJ, Williams GM, Brimble MA, Dingley AJ, Hay DL.

Br J Pharmacol. 2013 May;169(1):143-55. doi: 10.1111/bph.12118.

24.

Purification, crystallization and preliminary crystallographic analysis of the adhesion domain of Epf from Streptococcus pyogenes.

Linke C, Siemens N, Middleditch MJ, Kreikemeyer B, Baker EN.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1;68(Pt 7):793-7. doi: 10.1107/S1744309112020313. Epub 2012 Jun 28.

25.

A simple and rapid method for identifying and semi-quantifying peptide hormones in isolated pancreatic islets by direct-tissue matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

Stewart KW, Phillips AR, Whiting L, Jüllig M, Middleditch MJ, Cooper GJ.

Rapid Commun Mass Spectrom. 2011 Nov 30;25(22):3387-95. doi: 10.1002/rcm.5239.

PMID:
22002691
26.

Structural analyses of a purine biosynthetic enzyme from Mycobacterium tuberculosis reveal a novel bound nucleotide.

Le Nours J, Bulloch EM, Zhang Z, Greenwood DR, Middleditch MJ, Dickson JM, Baker EN.

J Biol Chem. 2011 Nov 25;286(47):40706-16. doi: 10.1074/jbc.M111.291138. Epub 2011 Sep 28.

27.

A unique case of neural amyloidoma diagnosed by mass spectrometry of formalin-fixed tissue using a novel preparative technique.

Jüllig M, Browett P, Middleditch MM, Prijic G, Kilfoyle D, Angelo N, Cooper GJ.

Amyloid. 2011 Sep;18(3):147-55. doi: 10.3109/13506129.2011.597798.

PMID:
21859255
28.

Towards energetically viable asymmetric deprotonations: selectivity at more elevated temperatures with C2-symmetric magnesium bisamides.

Bennie LS, Kerr WJ, Middleditch M, Watson AJ.

Chem Commun (Camb). 2011 Feb 28;47(8):2264-6. doi: 10.1039/c0cc04939e. Epub 2011 Jan 18.

29.

Illuminating the molecular basis of diabetic arteriopathy: a proteomic comparison of aortic tissue from diabetic and healthy rats.

Jüllig M, Chen X, Middleditch MJ, Vazhoor G, Hickey AJ, Gong D, Lu J, Zhang S, Phillips AR, Cooper GJ.

Proteomics. 2010 Sep;10(18):3367-78. doi: 10.1002/pmic.201000276.

PMID:
20707005
30.

Crystal structure of the minor pilin FctB reveals determinants of Group A streptococcal pilus anchoring.

Linke C, Young PG, Kang HJ, Bunker RD, Middleditch MJ, Caradoc-Davies TT, Proft T, Baker EN.

J Biol Chem. 2010 Jun 25;285(26):20381-9. doi: 10.1074/jbc.M109.089680. Epub 2010 Apr 27.

31.

Changes in the mesenteric lymph proteome induced by hemorrhagic shock.

Mittal A, Middleditch M, Ruggiero K, Loveday B, Delahunt B, Jüllig M, Cooper GJ, Windsor JA, Phillips AR.

Shock. 2010 Aug;34(2):140-9. doi: 10.1097/SHK.0b013e3181cd8631.

PMID:
20160674
32.

Quantitative proteomic profiling identifies new renal targets of copper(II)-selective chelation in the reversal of diabetic nephropathy in rats.

Gong D, Chen X, Middleditch M, Huang L, Vazhoor Amarsingh G, Reddy S, Lu J, Zhang S, Ruggiero K, Phillips AR, Cooper GJ.

Proteomics. 2009 Sep;9(18):4309-20. doi: 10.1002/pmic.200900285.

PMID:
19634143
33.

The proteome of mesenteric lymph during acute pancreatitis and implications for treatment.

Mittal A, Phillips AR, Middleditch M, Ruggiero K, Loveday B, Delahunt B, Cooper GJ, Windsor JA.

JOP. 2009 Mar 9;10(2):130-42.

34.

Isopeptide bonds in bacterial pili and their characterization by X-ray crystallography and mass spectrometry.

Kang HJ, Middleditch M, Proft T, Baker EN.

Biopolymers. 2009 Dec;91(12):1126-34. doi: 10.1002/bip.21170.

PMID:
19226623
35.

Proteins associated with immunopurified granules from a model pancreatic islet beta-cell system: proteomic snapshot of an endocrine secretory granule.

Hickey AJ, Bradley JW, Skea GL, Middleditch MJ, Buchanan CM, Phillips AR, Cooper GJ.

J Proteome Res. 2009 Jan;8(1):178-86. doi: 10.1021/pr800675k.

PMID:
19055480
36.

The proteome of rodent mesenteric lymph.

Mittal A, Middleditch M, Ruggiero K, Buchanan CM, Jullig M, Loveday B, Cooper GJ, Windsor JA, Phillips AR.

Am J Physiol Gastrointest Liver Physiol. 2008 Nov;295(5):G895-903. doi: 10.1152/ajpgi.90378.2008. Epub 2008 Sep 4.

37.

Mapping of the ATP-binding domain of human fructosamine 3-kinase-related protein by affinity labelling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.

Payne LS, Brown PM, Middleditch M, Baker E, Cooper GJ, Loomes KM.

Biochem J. 2008 Dec 1;416(2):281-8. doi: 10.1042/BJ20080389.

PMID:
18637789
38.

Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats.

Jüllig M, Hickey AJ, Chai CC, Skea GL, Middleditch MJ, Costa S, Choong SY, Philips AR, Cooper GJ.

Proteomics. 2008 Jun;8(12):2556-72. doi: 10.1002/pmic.200700977.

PMID:
18563753
39.

Identification of protein components from the mature ovary of the sea urchin Evechinus chloroticus (Echinodermata: Echinoidea).

Sewell MA, Eriksen S, Middleditch MJ.

Proteomics. 2008 Jun;8(12):2531-42. doi: 10.1002/pmic.200700995.

PMID:
18563751
40.

Emerging use of isotope ratio mass spectrometry as a tool for discrimination of 3,4-methylenedioxymethamphetamine by synthetic route.

Buchanan HA, Daéid NN, Meier-Augenstein W, Kemp HF, Kerr WJ, Middleditch M.

Anal Chem. 2008 May 1;80(9):3350-6. doi: 10.1021/ac702559s. Epub 2008 Mar 21.

PMID:
18355086
41.

Characterization of proteomic changes in cardiac mitochondria in streptozotocin-diabetic rats using iTRAQ™ isobaric tags.

Jüllig M, Hickey AJ, Middleditch MJ, Crossman DJ, Lee SC, Cooper GJ.

Proteomics Clin Appl. 2007 Jun;1(6):565-76. doi: 10.1002/prca.200600831.

PMID:
21136708
42.

Reversal of diabetes-evoked changes in mitochondrial protein expression of cardiac left ventricle by treatment with a copper(II)-selective chelator.

Jüllig M, Chen X, Hickey AJ, Crossman DJ, Xu A, Wang Y, Greenwood DR, Choong YS, Schönberger SJ, Middleditch MJ, Phillips AR, Cooper GJ.

Proteomics Clin Appl. 2007 Apr;1(4):387-99. doi: 10.1002/prca.200600770. Epub 2007 Mar 13.

PMID:
21136691
43.

A series of [3 + 2] cycloaddition products from the reaction of rhenium oxo complexes with diphenyl ketene.

Middleditch M, Anderson JC, Blake AJ, Wilson C.

Inorg Chem. 2007 Apr 2;46(7):2797-804. Epub 2007 Mar 6.

PMID:
17338517
44.

The structure of MbtI from Mycobacterium tuberculosis, the first enzyme in the biosynthesis of the siderophore mycobactin, reveals it to be a salicylate synthase.

Harrison AJ, Yu M, Gårdenborg T, Middleditch M, Ramsay RJ, Baker EN, Lott JS.

J Bacteriol. 2006 Sep;188(17):6081-91.

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