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Items: 1 to 50 of 104

1.

Comparison of Three Different TTF-1 Clones in Resected Primary Lung Cancer and Epithelial Pulmonary Metastases.

Vidarsdottir H, Tran L, Nodin B, Jirström K, Planck M, Mattsson JSM, Botling J, Micke P, Jönsson P, Brunnström H.

Am J Clin Pathol. 2018 Aug 30. doi: 10.1093/ajcp/aqy083. [Epub ahead of print]

PMID:
30169783
2.

An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas.

Miyashita N, Horie M, Suzuki HI, Yoshihara M, Djureinovic D, Persson J, Brunnström H, Lindskog C, Elfving H, Micke P, Saito A, Nagase T.

J Thorac Oncol. 2018 Aug 16. pii: S1556-0864(18)30933-X. doi: 10.1016/j.jtho.2018.07.096. [Epub ahead of print]

PMID:
30121393
3.

The Heidelberg compact electron beam ion traps.

Micke P, Kühn S, Buchauer L, Harries JR, Bücking TM, Blaum K, Cieluch A, Egl A, Hollain D, Kraemer S, Pfeifer T, Schmidt PO, Schüssler RX, Schweiger C, Stöhlker T, Sturm S, Wolf RN, Bernitt S, Crespo López-Urrutia JR.

Rev Sci Instrum. 2018 Jun;89(6):063109. doi: 10.1063/1.5026961.

PMID:
29960545
4.

An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer.

Horie M, Miyashita N, Mattsson JSM, Mikami Y, Sandelin M, Brunnström H, Micke P, Nagase T, Saito A.

J Pathol. 2018 Oct;246(2):154-165. doi: 10.1002/path.5109. Epub 2018 Aug 13.

PMID:
29876935
5.

Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer.

La Fleur L, Boura VF, Alexeyenko A, Berglund A, Pontén V, Mattsson JSM, Djureinovic D, Persson J, Brunnström H, Isaksson J, Brandén E, Koyi H, Micke P, Karlsson MCI, Botling J.

Int J Cancer. 2018 Apr 18. doi: 10.1002/ijc.31545. [Epub ahead of print]

PMID:
29667169
6.

Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle.

Westerlund K, Altai M, Mitran B, Konijnenberg M, Oroujeni M, Atterby C, de Jong M, Orlova A, Mattsson J, Micke P, Karlström AE, Tolmachev V.

J Nucl Med. 2018 Jul;59(7):1092-1098. doi: 10.2967/jnumed.118.208348. Epub 2018 Feb 9.

PMID:
29439013
7.

Multispectral imaging for quantitative and compartment-specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients.

Mezheyeuski A, Bergsland CH, Backman M, Djureinovic D, Sjöblom T, Bruun J, Micke P.

J Pathol. 2018 Apr;244(4):421-431. doi: 10.1002/path.5026. Epub 2018 Feb 5.

PMID:
29282718
8.

COX-2 expression and effects of celecoxib in addition to standard chemotherapy in advanced non-small cell lung cancer.

Gulyas M, Mattsson JSM, Lindgren A, Ek L, Lamberg Lundström K, Behndig A, Holmberg E, Micke P, Bergman B; Swedish Lung Cancer Study Group.

Acta Oncol. 2018 Feb;57(2):244-250. doi: 10.1080/0284186X.2017.1400685. Epub 2017 Nov 15.

PMID:
29140138
9.

RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer.

Rao S, Sigl V, Wimmer RA, Novatchkova M, Jais A, Wagner G, Handschuh S, Uribesalgo I, Hagelkruys A, Kozieradzki I, Tortola L, Nitsch R, Cronin SJ, Orthofer M, Branstetter D, Canon J, Rossi J, D'Arcangelo M, Botling J, Micke P, Fleur L, Edlund K, Bergqvist M, Ekman S, Lendl T, Popper H, Takayanagi H, Kenner L, Hirsch FR, Dougall W, Penninger JM.

Genes Dev. 2017 Oct 15;31(20):2099-2112. doi: 10.1101/gad.304162.117. Epub 2017 Nov 8.

10.

Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer.

Jabs V, Edlund K, König H, Grinberg M, Madjar K, Rahnenführer J, Ekman S, Bergkvist M, Holmberg L, Ickstadt K, Botling J, Hengstler JG, Micke P.

PLoS One. 2017 Nov 7;12(11):e0187246. doi: 10.1371/journal.pone.0187246. eCollection 2017.

11.

The integrative clinical impact of tumor-infiltrating T lymphocytes and NK cells in relation to B lymphocyte and plasma cell density in esophageal and gastric adenocarcinoma.

Svensson MC, Warfvinge CF, Fristedt R, Hedner C, Borg D, Eberhard J, Micke P, Nodin B, Leandersson K, Jirström K.

Oncotarget. 2017 Jul 21;8(42):72108-72126. doi: 10.18632/oncotarget.19437. eCollection 2017 Sep 22.

12.

A pathology atlas of the human cancer transcriptome.

Uhlen M, Zhang C, Lee S, Sjöstedt E, Fagerberg L, Bidkhori G, Benfeitas R, Arif M, Liu Z, Edfors F, Sanli K, von Feilitzen K, Oksvold P, Lundberg E, Hober S, Nilsson P, Mattsson J, Schwenk JM, Brunnström H, Glimelius B, Sjöblom T, Edqvist PH, Djureinovic D, Micke P, Lindskog C, Mardinoglu A, Ponten F.

Science. 2017 Aug 18;357(6352). pii: eaan2507. doi: 10.1126/science.aan2507.

PMID:
28818916
13.

Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC.

Horie M, Kaczkowski B, Ohshima M, Matsuzaki H, Noguchi S, Mikami Y, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest ARR, Takai D, Yamaguchi Y, Micke P, Saito A, Nagase T.

Mol Cancer Res. 2017 Oct;15(10):1354-1365. doi: 10.1158/1541-7786.MCR-17-0191. Epub 2017 Jul 11.

14.

The clinical impact of tumour-infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: A cohort study.

Berntsson J, Svensson MC, Leandersson K, Nodin B, Micke P, Larsson AH, Eberhard J, Jirström K.

Int J Cancer. 2017 Oct 15;141(8):1654-1666. doi: 10.1002/ijc.30869. Epub 2017 Jul 20.

15.

PD-L1 immunohistochemistry in clinical diagnostics of lung cancer: inter-pathologist variability is higher than assay variability.

Brunnström H, Johansson A, Westbom-Fremer S, Backman M, Djureinovic D, Patthey A, Isaksson-Mettävainio M, Gulyas M, Micke P.

Mod Pathol. 2017 Oct;30(10):1411-1421. doi: 10.1038/modpathol.2017.59. Epub 2017 Jun 30.

16.

Gene Expression Profiling of Large Cell Lung Cancer Links Transcriptional Phenotypes to the New Histological WHO 2015 Classification.

Karlsson A, Brunnström H, Micke P, Veerla S, Mattsson J, La Fleur L, Botling J, Jönsson M, Reuterswärd C, Planck M, Staaf J.

J Thorac Oncol. 2017 Aug;12(8):1257-1267. doi: 10.1016/j.jtho.2017.05.008. Epub 2017 May 20.

17.

Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

Grinberg M, Djureinovic D, Brunnström HR, Mattsson JS, Edlund K, Hengstler JG, La Fleur L, Ekman S, Koyi H, Branden E, Ståhle E, Jirström K, Tracy DK, Pontén F, Botling J, Rahnenführer J, Micke P.

Mod Pathol. 2017 Jul;30(7):964-977. doi: 10.1038/modpathol.2017.14. Epub 2017 Mar 10.

18.

Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel.

Grudén S, Sandelin M, Rasanen V, Micke P, Hedeland M, Axén N, Jeansson M.

Eur J Pharm Biopharm. 2017 May;114:186-193. doi: 10.1016/j.ejpb.2017.01.018. Epub 2017 Feb 1.

PMID:
28161551
19.

Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer.

Mathot L, Kundu S, Ljungström V, Svedlund J, Moens L, Adlerteg T, Falk-Sörqvist E, Rendo V, Bellomo C, Mayrhofer M, Cortina C, Sundström M, Micke P, Botling J, Isaksson A, Moustakas A, Batlle E, Birgisson H, Glimelius B, Nilsson M, Sjöblom T.

Cancer Res. 2017 Apr 1;77(7):1730-1740. doi: 10.1158/0008-5472.CAN-16-1921. Epub 2017 Jan 20.

20.

Prognostic impact of tumour-associated B cells and plasma cells in oesophageal and gastric adenocarcinoma.

Fristedt R, Borg D, Hedner C, Berntsson J, Nodin B, Eberhard J, Micke P, Jirström K.

J Gastrointest Oncol. 2016 Dec;7(6):848-859. doi: 10.21037/jgo.2016.11.07.

21.

Epsin Family Member 3 and Ribosome-Related Genes Are Associated with Late Metastasis in Estrogen Receptor-Positive Breast Cancer and Long-Term Survival in Non-Small Cell Lung Cancer Using a Genome-Wide Identification and Validation Strategy.

Hellwig B, Madjar K, Edlund K, Marchan R, Cadenas C, Heimes AS, Almstedt K, Lebrecht A, Sicking I, Battista MJ, Micke P, Schmidt M, Hengstler JG, Rahnenführer J.

PLoS One. 2016 Dec 7;11(12):e0167585. doi: 10.1371/journal.pone.0167585. eCollection 2016.

22.

Various Antibody Clones of Napsin A, Thyroid Transcription Factor 1, and p40 and Comparisons With Cytokeratin 5 and p63 in Histopathologic Diagnostics of Non-Small Cell Lung Carcinoma.

Tran L, Mattsson JS, Nodin B, Jönsson P, Planck M, Jirström K, Botling J, Micke P, Brunnström H.

Appl Immunohistochem Mol Morphol. 2016 Oct;24(9):648-659.

PMID:
26447895
23.

Profiling cancer testis antigens in non-small-cell lung cancer.

Djureinovic D, Hallström BM, Horie M, Mattsson JS, La Fleur L, Fagerberg L, Brunnström H, Lindskog C, Madjar K, Rahnenführer J, Ekman S, Ståhle E, Koyi H, Brandén E, Edlund K, Hengstler JG, Lambe M, Saito A, Botling J, Pontén F, Uhlén M, Micke P.

JCI Insight. 2016 Jul 7;1(10):e86837.

24.

Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis.

Horie M, Yamaguchi Y, Saito A, Nagase T, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Forrest AR, Hayashizaki Y, Suzutani T, Kappert K, Micke P, Ohshima M.

Sci Rep. 2016 Sep 20;6:33666. doi: 10.1038/srep33666.

25.

Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer.

Mattsson JS, Brunnström H, Jabs V, Edlund K, Jirström K, Mindus S, la Fleur L, Pontén F, Karlsson MG, Karlsson C, Koyi H, Brandén E, Botling J, Helenius G, Micke P, Svensson MA.

BMC Cancer. 2016 Aug 5;16:603. doi: 10.1186/s12885-016-2646-x.

26.

Prognostic impact of tumour-infiltrating B cells and plasma cells in colorectal cancer.

Berntsson J, Nodin B, Eberhard J, Micke P, Jirström K.

Int J Cancer. 2016 Sep 1;139(5):1129-39. doi: 10.1002/ijc.30138. Epub 2016 May 6.

27.

Prognostic impact of tumour-associated B cells and plasma cells in epithelial ovarian cancer.

Lundgren S, Berntsson J, Nodin B, Micke P, Jirström K.

J Ovarian Res. 2016 Apr 6;9:21. doi: 10.1186/s13048-016-0232-0.

28.

Fibroblast VEGF-receptor 1 expression as molecular target in periodontitis.

Ohshima M, Yamaguchi Y, Ambe K, Horie M, Saito A, Nagase T, Nakashima K, Ohki H, Kawai T, Abiko Y, Micke P, Kappert K.

J Clin Periodontol. 2016 Feb;43(2):128-37. doi: 10.1111/jcpe.12495. Epub 2016 Feb 23.

PMID:
26932322
29.

The Impact of the Fourth Edition of the WHO Classification of Lung Tumours on Histological Classification of Resected Pulmonary NSCCs.

Micke P, Mattsson JS, Djureinovic D, Nodin B, Jirström K, Tran L, Jönsson P, Planck M, Botling J, Brunnström H.

J Thorac Oncol. 2016 Jun;11(6):862-72. doi: 10.1016/j.jtho.2016.01.020. Epub 2016 Feb 9.

30.

The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling.

Raja E, Tzavlaki K, Vuilleumier R, Edlund K, Kahata K, Zieba A, Morén A, Watanabe Y, Voytyuk I, Botling J, Söderberg O, Micke P, Pyrowolakis G, Heldin CH, Moustakas A.

Oncotarget. 2016 Jan 12;7(2):1120-43. doi: 10.18632/oncotarget.6683.

31.

Identification of sample annotation errors in gene expression datasets.

Lohr M, Hellwig B, Edlund K, Mattsson JS, Botling J, Schmidt M, Hengstler JG, Micke P, Rahnenführer J.

Arch Toxicol. 2015 Dec;89(12):2265-72. doi: 10.1007/s00204-015-1632-4. Epub 2015 Nov 25.

32.

Basic principles of static proton low-resolution spin diffusion NMR in nanophase-separated materials with mobility contrast.

Schäler K, Roos M, Micke P, Golitsyn Y, Seidlitz A, Thurn-Albrecht T, Schneider H, Hempel G, Saalwächter K.

Solid State Nucl Magn Reson. 2015 Nov;72:50-63. doi: 10.1016/j.ssnmr.2015.09.001. Epub 2015 Sep 3.

PMID:
26404771
33.

Moderate MAS enhances local (1)H spin exchange and spin diffusion.

Roos M, Micke P, Saalwächter K, Hempel G.

J Magn Reson. 2015 Nov;260:28-37. doi: 10.1016/j.jmr.2015.08.016. Epub 2015 Sep 5.

PMID:
26397218
34.

HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples.

Moens LN, Falk-Sörqvist E, Ljungström V, Mattsson J, Sundström M, La Fleur L, Mathot L, Micke P, Nilsson M, Botling J.

J Mol Diagn. 2015 Nov;17(6):729-39. doi: 10.1016/j.jmoldx.2015.06.009. Epub 2015 Sep 3.

PMID:
26354930
35.

Patients with Non-small Cell Lung Cancer Analyzed for EGFR: Adherence to Guidelines, Prevalence and Outcome.

Sandelin M, Berglund A, Sundström M, Micke P, Ekman S, Bergqvist M, Bergström S, Koyi H, Brandén E, Janson C, Botling J.

Anticancer Res. 2015 Jul;35(7):3979-85.

PMID:
26124345
36.

Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer.

Birgisson H, Edlund K, Wallin U, Påhlman L, Kultima HG, Mayrhofer M, Micke P, Isaksson A, Botling J, Glimelius B, Sundström M.

BMC Cancer. 2015 Mar 14;15:125. doi: 10.1186/s12885-015-1144-x.

37.

LRIG1 is a prognostic biomarker in non-small cell lung cancer.

Kvarnbrink S, Karlsson T, Edlund K, Botling J, Lindquist D, Jirström K, Micke P, Henriksson R, Johansson M, Hedman H.

Acta Oncol. 2015;54(8):1113-9. doi: 10.3109/0284186X.2015.1021427. Epub 2015 Mar 27.

PMID:
25813475
38.

Coulomb crystallization of highly charged ions.

Schmöger L, Versolato OO, Schwarz M, Kohnen M, Windberger A, Piest B, Feuchtenbeiner S, Pedregosa-Gutierrez J, Leopold T, Micke P, Hansen AK, Baumann TM, Drewsen M, Ullrich J, Schmidt PO, López-Urrutia JR.

Science. 2015 Mar 13;347(6227):1233-6. doi: 10.1126/science.aaa2960.

39.

Immunohistochemistry-based prognostic biomarkers in NSCLC: novel findings on the road to clinical use?

Lindskog C, Edlund K, Mattsson JS, Micke P.

Expert Rev Mol Diagn. 2015 Apr;15(4):471-90. doi: 10.1586/14737159.2015.1002772. Epub 2015 Jan 19. Review.

PMID:
25599124
40.

Prognostic impact of COX-2 in non-small cell lung cancer: a comprehensive compartment-specific evaluation of tumor and stromal cell expression.

Mattsson JS, Bergman B, Grinberg M, Edlund K, Marincevic M, Jirström K, Pontén F, Hengstler JG, Rahnenführer J, Karlsson MG, Karlsson C, Helenius G, Botling J, Micke P, Gulyas M.

Cancer Lett. 2015 Jan 28;356(2 Pt B):837-45. doi: 10.1016/j.canlet.2014.10.032. Epub 2014 Oct 31.

PMID:
25449785
41.

1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer.

Mayrhofer M, Kultima HG, Birgisson H, Sundström M, Mathot L, Edlund K, Viklund B, Sjöblom T, Botling J, Micke P, Påhlman L, Glimelius B, Isaksson A.

BMC Cancer. 2014 Nov 24;14:872. doi: 10.1186/1471-2407-14-872.

42.

The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling.

Lindskog C, Fagerberg L, Hallström B, Edlund K, Hellwig B, Rahnenführer J, Kampf C, Uhlén M, Pontén F, Micke P.

FASEB J. 2014 Dec;28(12):5184-96. doi: 10.1096/fj.14-254862. Epub 2014 Aug 28.

PMID:
25169055
43.

Genomic and transcriptional alterations in lung adenocarcinoma in relation to smoking history.

Karlsson A, Ringnér M, Lauss M, Botling J, Micke P, Planck M, Staaf J.

Clin Cancer Res. 2014 Sep 15;20(18):4912-24. doi: 10.1158/1078-0432.CCR-14-0246. Epub 2014 Jul 18.

44.

An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer.

Noguchi S, Saito A, Horie M, Mikami Y, Suzuki HI, Morishita Y, Ohshima M, Abiko Y, Mattsson JS, König H, Lohr M, Edlund K, Botling J, Micke P, Nagase T.

Clin Cancer Res. 2014 Sep 1;20(17):4660-72. doi: 10.1158/1078-0432.CCR-13-3328. Epub 2014 Jun 20.

45.

Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer.

Micke P, Mattsson JS, Edlund K, Lohr M, Jirström K, Berglund A, Botling J, Rahnenfuehrer J, Marincevic M, Pontén F, Ekman S, Hengstler J, Wöll S, Sahin U, Türeci O.

Int J Cancer. 2014 Nov 1;135(9):2206-14. doi: 10.1002/ijc.28857. Epub 2014 Apr 8.

46.

Prognostic relevance of cancer-associated fibroblasts in human cancer.

Paulsson J, Micke P.

Semin Cancer Biol. 2014 Apr;25:61-8. doi: 10.1016/j.semcancer.2014.02.006. Epub 2014 Feb 19. Review.

PMID:
24560651
47.

A systematic analysis of commonly used antibodies in cancer diagnostics.

Gremel G, Bergman J, Djureinovic D, Edqvist PH, Maindad V, Bharambe BM, Khan WA, Navani S, Elebro J, Jirström K, Hellberg D, Uhlén M, Micke P, Pontén F.

Histopathology. 2014 Jan;64(2):293-305. doi: 10.1111/his.12255. Epub 2013 Nov 5.

PMID:
24330150
48.

In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics.

Grundberg I, Kiflemariam S, Mignardi M, Imgenberg-Kreuz J, Edlund K, Micke P, Sundström M, Sjöblom T, Botling J, Nilsson M.

Oncotarget. 2013 Dec;4(12):2407-18.

49.

Genomic and transcriptional alterations in lung adenocarcinoma in relation to EGFR and KRAS mutation status.

Planck M, Edlund K, Botling J, Micke P, Isaksson S, Staaf J.

PLoS One. 2013 Oct 24;8(10):e78614. doi: 10.1371/journal.pone.0078614. eCollection 2013.

50.

The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer.

Lohr M, Edlund K, Botling J, Hammad S, Hellwig B, Othman A, Berglund A, Lambe M, Holmberg L, Ekman S, Bergqvist M, Pontén F, Cadenas C, Marchan R, Hengstler JG, Rahnenführer J, Micke P.

Cancer Lett. 2013 Jun 10;333(2):222-8. doi: 10.1016/j.canlet.2013.01.036. Epub 2013 Jan 28.

PMID:
23370224

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