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Items: 1 to 50 of 134

1.

A clinical dose of angiotensin-converting enzyme (ACE) inhibitor and heterozygous ACE deletion exacerbate Alzheimer's disease pathology in mice.

Liu S, Ando F, Fujita Y, Liu J, Maeda T, Shen X, Kikuchi K, Matsumoto A, Yokomori M, Tanabe-Fujimura C, Shimokata H, Michikawa M, Komano H, Zou K.

J Biol Chem. 2019 Jun 21;294(25):9760-9770. doi: 10.1074/jbc.RA118.006420. Epub 2019 May 9.

PMID:
31072831
2.

Iso-α-Acids, Bitter Components in Beer, Suppress Inflammatory Responses and Attenuate Neural Hyperactivation in the Hippocampus.

Ano Y, Yoshikawa M, Takaichi Y, Michikawa M, Uchida K, Nakayama H, Takashima A.

Front Pharmacol. 2019 Feb 11;10:81. doi: 10.3389/fphar.2019.00081. eCollection 2019.

3.

Iron treatment inhibits Aβ42 deposition in vivo and reduces Aβ42/Aβ40 ratio.

Shen X, Liu J, Fujita Y, Liu S, Maeda T, Kikuchi K, Obara T, Takebe A, Sayama R, Takahashi T, Matsue A, Sera K, Michikawa M, Komano H, Zou K.

Biochem Biophys Res Commun. 2019 May 14;512(4):653-658. doi: 10.1016/j.bbrc.2019.01.119. Epub 2019 Feb 18.

PMID:
30791980
4.

Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models.

Higaki S, Muramatsu M, Matsuda A, Matsumoto K, Satoh JI, Michikawa M, Niida S.

PLoS One. 2018 May 8;13(5):e0196929. doi: 10.1371/journal.pone.0196929. eCollection 2018.

5.

Tau Depletion in APP Transgenic Mice Attenuates Task-Related Hyperactivation of the Hippocampus and Differentially Influences Locomotor Activity and Spatial Memory.

Yoshikawa M, Soeda Y, Michikawa M, Almeida OFX, Takashima A.

Front Neurosci. 2018 Mar 1;12:124. doi: 10.3389/fnins.2018.00124. eCollection 2018.

6.

Nasal obstruction during adolescence induces memory/learning impairments associated with BDNF/TrkB signaling pathway hypofunction and high corticosterone levels.

Ogawa T, Okihara H, Kokai S, Abe Y, Karin Harumi UK, Makiguchi M, Kato C, Yabushita T, Michikawa M, Ono T.

J Neurosci Res. 2018 Jun;96(6):1056-1065. doi: 10.1002/jnr.24216. Epub 2018 Feb 2.

PMID:
29392750
7.

Periodontitis induced by bacterial infection exacerbates features of Alzheimer's disease in transgenic mice.

Ishida N, Ishihara Y, Ishida K, Tada H, Funaki-Kato Y, Hagiwara M, Ferdous T, Abdullah M, Mitani A, Michikawa M, Matsushita K.

NPJ Aging Mech Dis. 2017 Nov 6;3:15. doi: 10.1038/s41514-017-0015-x. eCollection 2017.

8.

Sodium balance, circadian BP rhythm, heart rate variability, and intrarenal renin-angiotensin-aldosterone and dopaminergic systems in acute phase of ARB therapy.

Isobe-Sasaki Y, Fukuda M, Ogiyama Y, Sato R, Miura T, Fuwa D, Mizuno M, Matsuoka T, Shibata H, Ito H, Ono M, Abe-Dohmae S, Kiyono K, Yamamoto Y, Kobori H, Michikawa M, Hayano J, Ohte N.

Physiol Rep. 2017 Jun;5(11). pii: e13309. doi: 10.14814/phy2.13309.

9.

Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer's pathology.

Zhang Z, Takeda-Uchimura Y, Foyez T, Ohtake-Niimi S, Narentuya, Akatsu H, Nishitsuji K, Michikawa M, Wyss-Coray T, Kadomatsu K, Uchimura K.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2947-E2954. doi: 10.1073/pnas.1615036114. Epub 2017 Mar 20.

10.

Molar loss and powder diet leads to memory deficit and modifies the mRNA expression of brain-derived neurotrophic factor in the hippocampus of adult mice.

Takeda Y, Oue H, Okada S, Kawano A, Koretake K, Michikawa M, Akagawa Y, Tsuga K.

BMC Neurosci. 2016 Dec 5;17(1):81.

11.

Amyloid-β Reduces Exosome Release from Astrocytes by Enhancing JNK Phosphorylation.

Abdullah M, Takase H, Nunome M, Enomoto H, Ito J, Gong JS, Michikawa M.

J Alzheimers Dis. 2016 Jul 2;53(4):1433-41. doi: 10.3233/JAD-160292.

PMID:
27392863
12.

Addition of hydrochlorothiazide to angiotensin receptor blocker therapy can achieve a lower sodium balance with no acceleration of intrarenal renin angiotensin system in patients with chronic kidney disease.

Fuwa D, Fukuda M, Ogiyama Y, Sato R, Mizuno M, Miura T, Abe-Dohmae S, Michikawa M, Kobori H, Ohte N.

J Renin Angiotensin Aldosterone Syst. 2016 Jun 9;17(2):1470320316652032. doi: 10.1177/1470320316652032. Print 2016 Apr-Jun.

13.

ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production.

Sano O, Tsujita M, Shimizu Y, Kato R, Kobayashi A, Kioka N, Remaley AT, Michikawa M, Ueda K, Matsuo M.

PLoS One. 2016 May 19;11(5):e0155400. doi: 10.1371/journal.pone.0155400. eCollection 2016.

14.

Phosphatidylcholine protects neurons from toxic effects of amyloid β-protein in culture.

Ko M, Hattori T, Abdullah M, Gong JS, Yamane T, Michikawa M.

Brain Res. 2016 Jul 1;1642:376-383. doi: 10.1016/j.brainres.2016.04.035. Epub 2016 Apr 14.

PMID:
27086970
15.

Arachidonic or Docosahexaenoic Acid Diet Prevents Memory Impairment in Tg2576 Mice.

Hosono T, Mouri A, Nishitsuji K, Jung CG, Kontani M, Tokuda H, Kawashima H, Shibata H, Suzuki T, Nabehsima T, Michikawa M.

J Alzheimers Dis. 2015;48(1):149-62. doi: 10.3233/JAD-150341.

PMID:
26401936
16.

Angiotensin type 1a receptor deficiency decreases amyloid β-protein generation and ameliorates brain amyloid pathology.

Liu J, Liu S, Matsumoto Y, Murakami S, Sugakawa Y, Kami A, Tanabe C, Maeda T, Michikawa M, Komano H, Zou K.

Sci Rep. 2015 Jul 8;5:12059. doi: 10.1038/srep12059.

17.

Arachidonic acid diet attenuates brain Aβ deposition in Tg2576 mice.

Hosono T, Nishitsuji K, Nakamura T, Jung CG, Kontani M, Tokuda H, Kawashima H, Kiso Y, Suzuki T, Michikawa M.

Brain Res. 2015 Jul 10;1613:92-9. doi: 10.1016/j.brainres.2015.04.005. Epub 2015 Apr 13.

PMID:
25881896
18.

Biochemical properties in membrane of rat astrocytes under oxidative stress.

Ito JI, Nagayasu Y, Ogawa T, Okihara H, Michikawa M.

Brain Res. 2015 Jul 30;1615:1-11. doi: 10.1016/j.brainres.2015.04.008. Epub 2015 Apr 13.

PMID:
25881893
19.

Lysophosphatidylcholine increases the neurotoxicity of Alzheimer's amyloid β1-42 peptide: role of oligomer formation.

Sheikh AM, Michikawa M, Kim SU, Nagai A.

Neuroscience. 2015 Apr 30;292:159-69. doi: 10.1016/j.neuroscience.2015.02.034. Epub 2015 Feb 26.

PMID:
25727637
20.

Tooth loss might not alter molecular pathogenesis in an aged transgenic Alzheimer's disease model mouse.

Oue H, Miyamoto Y, Koretake K, Okada S, Doi K, Jung CG, Michikawa M, Akagawa Y.

Gerodontology. 2016 Sep;33(3):308-14. doi: 10.1111/ger.12153. Epub 2014 Sep 22.

PMID:
25243637
21.

ApoA-I/HDL Generation and Intracellular Cholesterol Transport through Cytosolic Lipid-Protein Particles in Astrocytes.

Ito J, Michikawa M.

J Lipids. 2014;2014:530720. doi: 10.1155/2014/530720. Epub 2014 Aug 13. Review.

22.

Auraptene increases the production of amyloid-β via c-Jun N-terminal kinase-dependent activation of γ-secretase.

Jung CG, Uhm KO, Horike H, Kim MJ, Misumi S, Ishida A, Ueda Y, Choi EK, Kim YS, Michikawa M, Hida H.

J Alzheimers Dis. 2015;43(4):1215-28. doi: 10.3233/JAD-141692.

PMID:
25147119
23.

ATBF1 is a novel amyloid-β protein precursor (AβPP) binding protein that affects AβPP expression.

Uhm KO, Kim MJ, Kawaguchi M, Akatsu H, Miura Y, Misumi S, Hida H, Choi EK, Kim YS, Michikawa M, Jung CG.

J Alzheimers Dis. 2015;43(1):243-57. doi: 10.3233/JAD-140612.

PMID:
25079792
24.

[Role of apolipoprotein E in the molecular pathomechanism of Alzheimer disease].

Michikawa M.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2014 Feb;34(1):5-9. Review. Japanese.

PMID:
25069266
25.

Astrocyte׳s endogenous apoE generates HDL-like lipoproteins using previously synthesized cholesterol through interaction with ABCA1.

Ito J, Nagayasu Y, Miura Y, Yokoyama S, Michikawa M.

Brain Res. 2014 Jun 27;1570:1-12. doi: 10.1016/j.brainres.2014.04.037. Epub 2014 May 9.

PMID:
24814386
26.

[Periodontal disease].

Michikawa M.

Nihon Rinsho. 2014 Apr;72(4):744-8. Review. Japanese.

PMID:
24796109
27.

Increasing cellular level of phosphatidic acid enhances FGF-1 production in long term-cultured rat astrocytes.

Nagayasu Y, Morita SY, Hayashi H, Miura Y, Yokoyama K, Michikawa M, Ito J.

Brain Res. 2014 May 14;1563:31-40. doi: 10.1016/j.brainres.2014.03.035. Epub 2014 Mar 29.

PMID:
24690199
28.

Liquid diet induces memory impairment accompanied by a decreased number of hippocampal neurons in mice.

Okihara H, Ito J, Kokai S, Ishida T, Hiranuma M, Kato C, Yabushita T, Ishida K, Ono T, Michikawa M.

J Neurosci Res. 2014 Aug;92(8):1010-7. doi: 10.1002/jnr.23383. Epub 2014 Mar 31.

PMID:
24687840
29.

Crystal structure and characterization of the glycoside hydrolase family 62 α-L-arabinofuranosidase from Streptomyces coelicolor.

Maehara T, Fujimoto Z, Ichinose H, Michikawa M, Harazono K, Kaneko S.

J Biol Chem. 2014 Mar 14;289(11):7962-72. doi: 10.1074/jbc.M113.540542. Epub 2014 Jan 30.

30.

Involvement of cdc42/Rho kinase in apoA-I-mediated cholesterol efflux through interaction between cytosolic lipid-protein particles and microtubules in rat astrocytes.

Kheirollah A, Nagayasu Y, Ueda H, Yokoyama S, Michikawa M, Ito J.

J Neurosci Res. 2014 Apr;92(4):455-63. doi: 10.1002/jnr.23324. Epub 2014 Jan 20.

PMID:
24446142
31.

KSGal6ST is essential for the 6-sulfation of galactose within keratan sulfate in early postnatal brain.

Hoshino H, Foyez T, Ohtake-Niimi S, Takeda-Uchimura Y, Michikawa M, Kadomatsu K, Uchimura K.

J Histochem Cytochem. 2014 Feb;62(2):145-56. doi: 10.1369/0022155413511619. Epub 2013 Oct 23.

32.

A low temperature-inducible protein AtSRC2 enhances the ROS-producing activity of NADPH oxidase AtRbohF.

Kawarazaki T, Kimura S, Iizuka A, Hanamata S, Nibori H, Michikawa M, Imai A, Abe M, Kaya H, Kuchitsu K.

Biochim Biophys Acta. 2013 Dec;1833(12):2775-2780. doi: 10.1016/j.bbamcr.2013.06.024. Epub 2013 Jul 16.

33.

Tooth loss induces memory impairment and neuronal cell loss in APP transgenic mice.

Oue H, Miyamoto Y, Okada S, Koretake K, Jung CG, Michikawa M, Akagawa Y.

Behav Brain Res. 2013 Sep 1;252:318-25. doi: 10.1016/j.bbr.2013.06.015. Epub 2013 Jun 15.

PMID:
23773908
34.

Enhancement of FGF-1 release along with cytosolic proteins from rat astrocytes by hydrogen peroxide.

Ito J, Nagayasu Y, Hoshikawa M, Kato KH, Miura Y, Asai K, Hayashi H, Yokoyama S, Michikawa M.

Brain Res. 2013 Jul 19;1522:12-21. doi: 10.1016/j.brainres.2013.05.035. Epub 2013 May 29.

PMID:
23727614
35.

Aβ43 is the earliest-depositing Aβ species in APP transgenic mouse brain and is converted to Aβ41 by two active domains of ACE.

Zou K, Liu J, Watanabe A, Hiraga S, Liu S, Tanabe C, Maeda T, Terayama Y, Takahashi S, Michikawa M, Komano H.

Am J Pathol. 2013 Jun;182(6):2322-31. doi: 10.1016/j.ajpath.2013.01.053. Epub 2013 Apr 4.

PMID:
23562443
36.

The structure of a Streptomyces avermitilis α-L-rhamnosidase reveals a novel carbohydrate-binding module CBM67 within the six-domain arrangement.

Fujimoto Z, Jackson A, Michikawa M, Maehara T, Momma M, Henrissat B, Gilbert HJ, Kaneko S.

J Biol Chem. 2013 Apr 26;288(17):12376-85. doi: 10.1074/jbc.M113.460097. Epub 2013 Mar 13.

37.

The CBL-interacting protein kinase CIPK26 is a novel interactor of Arabidopsis NADPH oxidase AtRbohF that negatively modulates its ROS-producing activity in a heterologous expression system.

Kimura S, Kawarazaki T, Nibori H, Michikawa M, Imai A, Kaya H, Kuchitsu K.

J Biochem. 2013 Feb;153(2):191-5. doi: 10.1093/jb/mvs132. Epub 2012 Nov 18.

PMID:
23162070
38.

Characterization of an endo-processive-type xyloglucanase having a β-1,4-glucan-binding module and an endo-type xyloglucanase from Streptomyces avermitilis.

Ichinose H, Araki Y, Michikawa M, Harazono K, Yaoi K, Karita S, Kaneko S.

Appl Environ Microbiol. 2012 Nov;78(22):7939-45. doi: 10.1128/AEM.01762-12. Epub 2012 Aug 31.

39.

[Tg2576 mouse model].

Jung CG, Michikawa M.

Nihon Rinsho. 2011 Oct;69 Suppl 8:252-5. Japanese. No abstract available.

PMID:
22787791
40.

[Current state of Alzheimer's disease models: a brief overview].

Michikawa M.

Nihon Rinsho. 2011 Oct;69 Suppl 8:233-40. Japanese. No abstract available.

PMID:
22787788
41.

Heparan sulfate subdomains that are degraded by Sulf accumulate in cerebral amyloid ß plaques of Alzheimer's disease: evidence from mouse models and patients.

Hosono-Fukao T, Ohtake-Niimi S, Hoshino H, Britschgi M, Akatsu H, Hossain MM, Nishitsuji K, van Kuppevelt TH, Kimata K, Michikawa M, Wyss-Coray T, Uchimura K.

Am J Pathol. 2012 May;180(5):2056-67. doi: 10.1016/j.ajpath.2012.01.015. Epub 2012 Mar 17.

PMID:
22429964
42.

Structural and biochemical characterization of glycoside hydrolase family 79 β-glucuronidase from Acidobacterium capsulatum.

Michikawa M, Ichinose H, Momma M, Biely P, Jongkees S, Yoshida M, Kotake T, Tsumuraya Y, Withers SG, Fujimoto Z, Kaneko S.

J Biol Chem. 2012 Apr 20;287(17):14069-77. doi: 10.1074/jbc.M112.346288. Epub 2012 Feb 24.

43.

Protein phosphorylation is a prerequisite for the Ca2+-dependent activation of Arabidopsis NADPH oxidases and may function as a trigger for the positive feedback regulation of Ca2+ and reactive oxygen species.

Kimura S, Kaya H, Kawarazaki T, Hiraoka G, Senzaki E, Michikawa M, Kuchitsu K.

Biochim Biophys Acta. 2012 Feb;1823(2):398-405. doi: 10.1016/j.bbamcr.2011.09.011. Epub 2011 Oct 6.

44.

RB4CD12 epitope expression and heparan sulfate disaccharide composition in brain vasculature.

Hosono-Fukao T, Ohtake-Niimi S, Nishitsuji K, Hossain MM, van Kuppevelt TH, Michikawa M, Uchimura K.

J Neurosci Res. 2011 Nov;89(11):1840-8. doi: 10.1002/jnr.22690. Epub 2011 Jul 29.

PMID:
21805491
45.

Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons.

Jung CG, Uhm KO, Miura Y, Hosono T, Horike H, Khanna KK, Kim MJ, Michikawa M.

Mol Neurodegener. 2011 Jul 5;6:47. doi: 10.1186/1750-1326-6-47.

46.

ER-stress-inducible Herp, facilitates the degradation of immature nicastrin.

Marutani T, Maeda T, Tanabe C, Zou K, Araki W, Kokame K, Michikawa M, Komano H.

Biochim Biophys Acta. 2011 Aug;1810(8):790-8. doi: 10.1016/j.bbagen.2011.04.017. Epub 2011 May 12.

PMID:
21600962
47.

Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain barrier model.

Nishitsuji K, Hosono T, Nakamura T, Bu G, Michikawa M.

J Biol Chem. 2011 May 20;286(20):17536-42. doi: 10.1074/jbc.M111.225532. Epub 2011 Apr 6.

48.

Association between cognitive function and plasma lipids of the elderly after controlling for apolipoprotein E genotype.

Yasuno F, Tanimukai S, Sasaki M, Hidaka S, Ikejima C, Yamashita F, Kodama C, Mizukami K, Michikawa M, Asada T.

Am J Geriatr Psychiatry. 2012 Jul;20(7):574-83. doi: 10.1097/JGP.0b013e318211819b.

PMID:
21407046
49.

Dissociation of β-amyloid from lipoprotein in cerebrospinal fluid from Alzheimer's disease accelerates β-amyloid-42 assembly.

Takamura A, Kawarabayashi T, Yokoseki T, Shibata M, Morishima-Kawashima M, Saito Y, Murayama S, Ihara Y, Abe K, Shoji M, Michikawa M, Matsubara E.

J Neurosci Res. 2011 Jun;89(6):815-21. doi: 10.1002/jnr.22615. Epub 2011 Mar 10.

PMID:
21394760
50.

Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse.

Takamura A, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Mouri A, Nabeshima T, Sun H, Abe K, Urisu T, Yamamoto N, Shoji M, Yanagisawa K, Michikawa M, Matsubara E.

Mol Neurodegener. 2011 Mar 6;6(1):20. doi: 10.1186/1750-1326-6-20.

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