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Items: 1 to 50 of 173

1.

Safety and efficacy of immunoadsorption versus plasma exchange in steroid-refractory relapse of multiple sclerosis and clinically isolated syndrome: A randomised, parallel-group, controlled trial.

Dorst J, Fangerau T, Taranu D, Eichele P, Dreyhaupt J, Michels S, Schuster J, Ludolph AC, Senel M, Tumani H.

EClinicalMedicine. 2019 Nov 14;16:98-106. doi: 10.1016/j.eclinm.2019.10.017. eCollection 2019 Nov.

PMID:
31832624
2.

Interaction of the Psychiatric Risk Gene Cacna1c With Post-weaning Social Isolation or Environmental Enrichment Does Not Affect Brain Mitochondrial Bioenergetics in Rats.

Michels S, Dolga AM, Braun MD, Kisko TM, Sungur AÖ, Witt SH, Rietschel M, Dempfle A, Wöhr M, Schwarting RKW, Culmsee C.

Front Cell Neurosci. 2019 Oct 25;13:483. doi: 10.3389/fncel.2019.00483. eCollection 2019.

3.

Comparison of in Situ and Extraction-Based Methods for the Detection of ROS1 Rearrangements in Solid Tumors.

Heydt C, Ruesseler V, Pappesch R, Wagener S, Haak A, Siebolts U, Riedel R, Michels S, Wolf J, Schultheis AM, Rehker J, Buettner R, Merkelbach-Bruse S.

J Mol Diagn. 2019 Nov;21(6):971-984. doi: 10.1016/j.jmoldx.2019.06.006. Epub 2019 Aug 2.

PMID:
31382035
4.

Optical Coherence Tomography Angiography (OCT-A) in a Patient with Occult Retinal Dysfunction.

Wons J, Dinges J, Becker MD, Michels S.

Case Rep Ophthalmol Med. 2019 Jun 24;2019:4349692. doi: 10.1155/2019/4349692. eCollection 2019.

5.

Acquired KRAS mutation and loss of low-level MET amplification after durable response to crizotinib in a patient with lung adenocarcinoma.

Riedel R, Michels S, Heydt C, Siemanowski J, Kobe C, Bunck A, Schäfer S, Fischer RN, Scheffler M, Abdulla DSY, Nogová L, Koleczko S, Merkelbach-Bruse S, Büttner R, Wolf J.

Lung Cancer. 2019 Jul;133:20-22. doi: 10.1016/j.lungcan.2019.05.006. Epub 2019 May 6.

PMID:
31200822
6.

Protamine Sulfate Induces Mitochondrial Hyperpolarization and a Subsequent Increase in Reactive Oxygen Species Production.

Ramzan R, Michels S, Weber P, Rhiel A, Irqsusi M, Rastan AJ, Culmsee C, Vogt S.

J Pharmacol Exp Ther. 2019 Aug;370(2):308-317. doi: 10.1124/jpet.119.257725. Epub 2019 Jun 3.

PMID:
31160469
7.

18F-FDG PET/CT: an unexpected case of Huntington's disease.

Michels S, Buchholz HG, Rosar F, Heinrich I, Hoffmann MA, Schweiger S, Tüscher O, Schreckenberger M.

BMC Neurol. 2019 May 1;19(1):78. doi: 10.1186/s12883-019-1311-9.

8.

Safety and Efficacy of Crizotinib in Patients With Advanced or Metastatic ROS1-Rearranged Lung Cancer (EUCROSS): A European Phase II Clinical Trial.

Michels S, Massutí B, Schildhaus HU, Franklin J, Sebastian M, Felip E, Grohé C, Rodriguez-Abreu D, Abdulla DSY, Bischoff H, Brandts C, Carcereny E, Corral J, Dingemans AC, Pereira E, Fassunke J, Fischer RN, Gardizi M, Heukamp L, Insa A, Kron A, Menon R, Persigehl T, Reck M, Riedel R, Rothschild SI, Scheel AH, Scheffler M, Schmalz P, Smit EF, Limburg M, Provencio M, Karachaliou N, Merkelbach-Bruse S, Hellmich M, Nogova L, Büttner R, Rosell R, Wolf J.

J Thorac Oncol. 2019 Jul;14(7):1266-1276. doi: 10.1016/j.jtho.2019.03.020. Epub 2019 Apr 9.

PMID:
30978502
9.

Influenza virus infection as well as immunization with DNA encoding haemagglutinin protein induces potent antibody-dependent phagocytosis (ADP) and monocyte infection-enhancing responses in macaques.

Koopman G, Mortier D, Michels S, Hofman S, Fagrouch Z, Remarque EJ, Verschoor EJ, Mooij P, Bogers WMJM.

J Gen Virol. 2019 May;100(5):738-751. doi: 10.1099/jgv.0.001251. Epub 2019 Mar 28.

PMID:
30920368
10.

Mitochondria, Microglia, and the Immune System-How Are They Linked in Affective Disorders?

Culmsee C, Michels S, Scheu S, Arolt V, Dannlowski U, Alferink J.

Front Psychiatry. 2019 Jan 9;9:739. doi: 10.3389/fpsyt.2018.00739. eCollection 2018. Review.

11.

K-ras Mutation Subtypes in NSCLC and Associated Co-occuring Mutations in Other Oncogenic Pathways.

Scheffler M, Ihle MA, Hein R, Merkelbach-Bruse S, Scheel AH, Siemanowski J, Brägelmann J, Kron A, Abedpour N, Ueckeroth F, Schüller M, Koleczko S, Michels S, Fassunke J, Pasternack H, Heydt C, Serke M, Fischer R, Schulte W, Gerigk U, Nogova L, Ko YD, Abdulla DSY, Riedel R, Kambartel KO, Lorenz J, Sauerland I, Randerath W, Kaminsky B, Hagmeyer L, Grohé C, Eisert A, Frank R, Gogl L, Schaepers C, Holzem A, Hellmich M, Thomas RK, Peifer M, Sos ML, Büttner R, Wolf J.

J Thorac Oncol. 2019 Apr;14(4):606-616. doi: 10.1016/j.jtho.2018.12.013. Epub 2018 Dec 31.

12.

Sex-dependent effects of Cacna1c haploinsufficiency on juvenile social play behavior and pro-social 50-kHz ultrasonic communication in rats.

Kisko TM, Braun MD, Michels S, Witt SH, Rietschel M, Culmsee C, Schwarting RKW, Wöhr M.

Genes Brain Behav. 2018 Dec 27:e12552. doi: 10.1111/gbb.12552. [Epub ahead of print]

PMID:
30592145
13.

A semi-mechanistic model describing the influence of light and temperature on the respiration and photosynthetic growth of Chlorella vulgaris.

Manhaeghe D, Michels S, Rousseau DPL, Van Hulle SWH.

Bioresour Technol. 2019 Feb;274:361-370. doi: 10.1016/j.biortech.2018.11.097. Epub 2018 Nov 29.

PMID:
30537594
14.

Monitoring Treatment Response to Erlotinib in EGFR-mutated Non-small-cell Lung Cancer Brain Metastases Using Serial O-(2-[18F]fluoroethyl)-L-tyrosine PET.

Abdulla DSY, Scheffler M, Brandes V, Ruge M, Kunze S, Merkelbach-Bruse S, Nogova L, Michels S, Fischer R, Riedel R, Büttner R, Persigehl T, Grau S, Galldiks N, Drzezga A, Kobe C, Wolf J.

Clin Lung Cancer. 2019 Mar;20(2):e148-e151. doi: 10.1016/j.cllc.2018.10.011. Epub 2018 Nov 5. No abstract available.

15.

Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors.

Fassunke J, Müller F, Keul M, Michels S, Dammert MA, Schmitt A, Plenker D, Lategahn J, Heydt C, Brägelmann J, Tumbrink HL, Alber Y, Klein S, Heimsoeth A, Dahmen I, Fischer RN, Scheffler M, Ihle MA, Priesner V, Scheel AH, Wagener S, Kron A, Frank K, Garbert K, Persigehl T, Püsken M, Haneder S, Schaaf B, Rodermann E, Engel-Riedel W, Felip E, Smit EF, Merkelbach-Bruse S, Reinhardt HC, Kast SM, Wolf J, Rauh D, Büttner R, Sos ML.

Nat Commun. 2018 Nov 7;9(1):4655. doi: 10.1038/s41467-018-07078-0.

16.

[Precision pulse capsulotomy : The new capsulorhexis?]

Becker MD, Michels S, Lortz S, Kaminski S.

Ophthalmologe. 2019 Mar;116(3):288-290. doi: 10.1007/s00347-018-0807-9. Review. German.

PMID:
30367232
17.

Efficacy and safety analysis of the German expanded access program of osimertinib in patients with advanced, T790M-positive non-small cell lung cancer.

Stratmann JA, Michels S, Hornetz S, Christoph DC, Sackmann S, Spengler W, Bischoff H, Schäfer M, Alt J, Müller A, Laack E, Kimmich M, Griesinger F, Sebastian M.

J Cancer Res Clin Oncol. 2018 Dec;144(12):2457-2463. doi: 10.1007/s00432-018-2754-x. Epub 2018 Sep 22.

PMID:
30244389
18.

Impact of TP53 mutation status on systemic treatment outcome in ALK-rearranged non-small-cell lung cancer.

Kron A, Alidousty C, Scheffler M, Merkelbach-Bruse S, Seidel D, Riedel R, Ihle MA, Michels S, Nogova L, Fassunke J, Heydt C, Kron F, Ueckeroth F, Serke M, Krüger S, Grohe C, Koschel D, Benedikter J, Kaminsky B, Schaaf B, Braess J, Sebastian M, Kambartel KO, Thomas R, Zander T, Schultheis AM, Büttner R, Wolf J.

Ann Oncol. 2018 Oct 1;29(10):2068-2075. doi: 10.1093/annonc/mdy333.

19.
20.

Microvascular abnormalities secondary to radiation therapy in neovascular age-related macular degeneration: findings from the INTREPID clinical trial.

Freiberg FJ, Michels S, Muldrew A, Slakter J, O'Shaughnessy D, Czeszynski A, Danielson L, Jackson TL, Chakravarthy U.

Br J Ophthalmol. 2019 Apr;103(4):469-474. doi: 10.1136/bjophthalmol-2018-311865. Epub 2018 Jun 21.

PMID:
29930098
21.

Psychiatric risk gene Cacna1c determines mitochondrial resilience against oxidative stress in neurons.

Michels S, Wöhr M, Schwarting RK, Culmsee C.

Cell Death Dis. 2018 May 29;9(6):645. doi: 10.1038/s41419-018-0676-9. No abstract available.

22.

Downregulation of the psychiatric susceptibility gene Cacna1c promotes mitochondrial resilience to oxidative stress in neuronal cells.

Michels S, Ganjam GK, Martins H, Schratt GM, Wöhr M, Schwarting RKW, Culmsee C.

Cell Death Discov. 2018 May 10;4:54. doi: 10.1038/s41420-018-0061-6. eCollection 2018.

23.

Cacna1c haploinsufficiency leads to pro-social 50-kHz ultrasonic communication deficits in rats.

Kisko TM, Braun MD, Michels S, Witt SH, Rietschel M, Culmsee C, Schwarting RKW, Wöhr M.

Dis Model Mech. 2018 Jun 20;11(6). pii: dmm034116. doi: 10.1242/dmm.034116.

24.

Novel approaches against epidermal growth factor receptor tyrosine kinase inhibitor resistance.

Heydt C, Michels S, Thress KS, Bergner S, Wolf J, Buettner R.

Oncotarget. 2018 Mar 8;9(20):15418-15434. doi: 10.18632/oncotarget.24624. eCollection 2018 Mar 16. Review.

25.

Clinical and Pathological Characteristics of KEAP1- and NFE2L2-Mutated Non-Small Cell Lung Carcinoma (NSCLC).

Frank R, Scheffler M, Merkelbach-Bruse S, Ihle MA, Kron A, Rauer M, Ueckeroth F, König K, Michels S, Fischer R, Eisert A, Fassunke J, Heydt C, Serke M, Ko YD, Gerigk U, Geist T, Kaminsky B, Heukamp LC, Clement-Ziza M, Büttner R, Wolf J.

Clin Cancer Res. 2018 Jul 1;24(13):3087-3096. doi: 10.1158/1078-0432.CCR-17-3416. Epub 2018 Apr 3.

26.

[Functional and Anatomic Outcomes of Primary and Secondary Internal Limiting Membrane Transplantation in Large and Persistent Macular Holes].

Hess JA, Michels S, Becker MD.

Klin Monbl Augenheilkd. 2018 Oct;235(10):1159-1164. doi: 10.1055/s-0043-121032. Epub 2017 Nov 20. German.

PMID:
29156470
27.

COMPARISON OF RESOLUTION OF VITREOMACULAR TRACTION AFTER OCRIPLASMIN TREATMENT OR VITRECTOMY.

Scholz P, Sitnilska V, Hess J, Becker M, Michels S, Fauser S.

Retina. 2019 Jan;39(1):180-185. doi: 10.1097/IAE.0000000000001926.

PMID:
29135889
28.

Mutations of KIF5C cause a neurodevelopmental disorder of infantile-onset epilepsy, absent language, and distinctive malformations of cortical development.

Michels S, Foss K, Park K, Golden-Grant K, Saneto R, Lopez J, Mirzaa GM.

Am J Med Genet A. 2017 Dec;173(12):3127-3131. doi: 10.1002/ajmg.a.38496. Epub 2017 Oct 19.

29.

SAVE-AMD: Safety of VEGF Inhibitors in Age-Related Macular Degeneration.

Enseleit F, Michels S, Sudano I, Stahel M, Zweifel S, Schlager O, Becker M, Winnik S, Nägele M, Flammer AJ, Neidhart M, Graf N, Matter CM, Seifert B, Lüscher TF, Ruschitzka F.

Ophthalmologica. 2017;238(4):205-216. doi: 10.1159/000478665. Epub 2017 Sep 2.

30.

Long-Term Intravitreal Dexamethasone Treatment in Eyes with Pretreated Chronic Diabetic Macular Edema.

Zandi S, Lereuil T, Freiberg F, Pfau M, Pfister IB, Gerhardt C, Michels S, Kodjikian L, Garweg JG.

J Ocul Pharmacol Ther. 2017 Oct;33(8):620-628. doi: 10.1089/jop.2017.0020. Epub 2017 Aug 24.

PMID:
28836880
31.

Reply.

Freiberg F, Michels S.

Retina. 2017 Sep;37(9):e107-e108. doi: 10.1097/IAE.0000000000001808. No abstract available.

PMID:
28820852
32.

IMPACT OF LONG-TERM INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR ON PREEXISTING MICROSTRUCTURAL ALTERATIONS IN DIABETIC MACULAR EDEMA.

Wirth MA, Wons J, Freiberg FJ, Becker MD, Michels S.

Retina. 2018 Sep;38(9):1824-1829. doi: 10.1097/IAE.0000000000001788.

33.

Angio-OCT de la zona avascular foveal en ojos con oclusión venosa de la retina.

Wons J, Pfau M, Wirth MA, Freiberg FJ, Becker MD, Michels S.

Ophthalmologica. 2017;238 Suppl 1:39-47. doi: 10.1159/000477515. Epub 2017 Jul 11.

34.

Mechanisms of Primary Drug Resistance in FGFR1-Amplified Lung Cancer.

Malchers F, Ercanoglu M, Schütte D, Castiglione R, Tischler V, Michels S, Dahmen I, Brägelmann J, Menon R, Heuckmann JM, George J, Ansén S, Sos ML, Soltermann A, Peifer M, Wolf J, Büttner R, Thomas RK.

Clin Cancer Res. 2017 Sep 15;23(18):5527-5536. doi: 10.1158/1078-0432.CCR-17-0478. Epub 2017 Jun 19.

35.

Economic burden of clinical trials in lung cancer in a German Comprehensive Cancer Center.

Kron F, Kostenko A, Scheffler M, Müller D, Glossmann JP, Fischer R, Michels S, Nogova L, Hallek M, Zander T, Wolf J.

Lung Cancer. 2017 Jun;108:134-139. doi: 10.1016/j.lungcan.2017.03.018. Epub 2017 Mar 30.

PMID:
28625625
36.

Phenotypic and functional characterization of T cells in white matter lesions of multiple sclerosis patients.

van Nierop GP, van Luijn MM, Michels SS, Melief MJ, Janssen M, Langerak AW, Ouwendijk WJD, Hintzen RQ, Verjans GMGM.

Acta Neuropathol. 2017 Sep;134(3):383-401. doi: 10.1007/s00401-017-1744-4. Epub 2017 Jun 17.

37.

Torpedo Maculopathy Associated with Choroidal Neovascularization.

Jurjevic D, Böni C, Barthelmes D, Fasler K, Becker M, Michels S, Stemmle J, Herbort C, Zweifel SA.

Klin Monbl Augenheilkd. 2017 Apr;234(4):508-514. doi: 10.1055/s-0043-100230. Epub 2017 May 3.

PMID:
28470647
38.

Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.

Gautschi O, Milia J, Filleron T, Wolf J, Carbone DP, Owen D, Camidge R, Narayanan V, Doebele RC, Besse B, Remon-Masip J, Janne PA, Awad MM, Peled N, Byoung CC, Karp DD, Van Den Heuvel M, Wakelee HA, Neal JW, Mok TSK, Yang JCH, Ou SI, Pall G, Froesch P, Zalcman G, Gandara DR, Riess JW, Velcheti V, Zeidler K, Diebold J, Früh M, Michels S, Monnet I, Popat S, Rosell R, Karachaliou N, Rothschild SI, Shih JY, Warth A, Muley T, Cabillic F, Mazières J, Drilon A.

J Clin Oncol. 2017 May 1;35(13):1403-1410. doi: 10.1200/JCO.2016.70.9352. Epub 2017 Mar 13.

39.

Comparison of Progression Rate of Retinal Pigment Epithelium Loss in Patients with Neovascular Age-Related Macular Degeneration Treated with Ranibizumab and Aflibercept.

Wons J, Wirth MA, Graf N, Becker MD, Michels S.

J Ophthalmol. 2017;2017:7432739. doi: 10.1155/2017/7432739. Epub 2017 Feb 20.

40.

ALKG1269A mutation as a potential mechanism of acquired resistance to crizotinib in an ALK-rearranged inflammatory myofibroblastic tumor.

Michels SYF, Scheel AH, Wündisch T, Heuckmann JM, Menon R, Puesken M, Kobe C, Pasternack H, Heydt C, Scheffler M, Fischer R, Schultheis AM, Merkelbach-Bruse S, Heukamp L, Büttner R, Wolf J.

NPJ Precis Oncol. 2017 Mar 20;1(1):4. doi: 10.1038/s41698-017-0004-3. eCollection 2017.

41.

LOW ENDOPHTHALMITIS RATES AFTER INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTIONS IN AN OPERATION ROOM: A Retrospective Multicenter Study.

Freiberg FJ, Brynskov T, Munk MR, Sørensen TL, Wolf S, Wirth MA, Becker M, Michels S.

Retina. 2017 Dec;37(12):2341-2346. doi: 10.1097/IAE.0000000000001488.

PMID:
28099318
42.

Stratified Treatment in Lung Cancer.

Michels S, Wolf J.

Oncol Res Treat. 2016;39(12):760-766. Epub 2016 Nov 24. Review.

43.
44.

The Impact of Crunchy Wednesdays on Happy Meal Fruit Orders: Analysis of Sales Data in France, 2009-2013.

Drewnowski A, Michels S, Leroy D.

J Nutr Educ Behav. 2017 Mar;49(3):236-240.e1. doi: 10.1016/j.jneb.2016.10.005. Epub 2016 Nov 11.

45.

Optical coherence tomography angiography in age-related macular degeneration: persistence of vascular network in quiescent choroidal neovascularization.

Wirth MA, Freiberg F, Pfau M, Wons J, Becker MD, Michels S.

Acta Ophthalmol. 2017 Jun;95(4):428-430. doi: 10.1111/aos.13226. Epub 2016 Sep 23. Review. No abstract available.

46.

[Correction for: Switching Therapy from Ranibizumab and/or Bevacizumab to Aflibercept in Neovascular Age-Related Macular Degeneration (AMD): One-Year Results].

Pfau M, Fassnacht-Riederle HM, Freiberg FJ, Wons JB, Wirth M, Becker MD, Michels S.

Klin Monbl Augenheilkd. 2016 Aug;233(8):e3. doi: 10.1055/s-0042-115798. Epub 2016 Sep 6. German. No abstract available.

PMID:
27599047
47.

Assistive Device for Efficient Intravitreal Injections.

Ullrich F, Michels S, Lehmann D, Pieters RS, Becker M, Nelson BJ.

Ophthalmic Surg Lasers Imaging Retina. 2016 Aug 1;47(8):752-62. doi: 10.3928/23258160-20160808-09. Review.

PMID:
27548453
48.

Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner.

Jokić M, Vlašić I, Rinneburger M, Klümper N, Spiro J, Vogel W, Offermann A, Kümpers C, Fritz C, Schmitt A, Riabinska A, Wittersheim M, Michels S, Ozretić L, Florin A, Welcker D, Akyuz MD, Nowak M, Erkel M, Wolf J, Büttner R, Schumacher B, Thomale J, Persigehl T, Maintz D, Perner S, Reinhardt HC.

Mol Cancer Res. 2016 Nov;14(11):1110-1123. Epub 2016 Aug 11.

49.

Regulatory Factors Influencing Usage of Retinal Pharmaceuticals: A Look Both Home and Abroad.

Croft DE, Wykoff CC, Michels S, Chakravarthy U, Cruess AF.

Am J Ophthalmol. 2016 Sep;169:xiv-xvi. doi: 10.1016/j.ajo.2016.06.040. Epub 2016 Jul 30. No abstract available.

PMID:
27485923
50.

Response of Postoperative and Chronic Uveitic Cystoid Macular Edema to a Dexamethasone-Based Intravitreal Implant (Ozurdex).

Garweg JG, Baglivo E, Freiberg FJ, Pfau M, Pfister IB, Michels S, Zandi S.

J Ocul Pharmacol Ther. 2016 Sep;32(7):442-50. doi: 10.1089/jop.2016.0035. Epub 2016 Aug 1.

PMID:
27479780

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