Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 294

1.

Characteristics in Non-Vitamin K Antagonist Oral Anticoagulant-Related Intracerebral Hemorrhage.

Gerner ST, Kuramatsu JB, Sembill JA, Sprügel MI, Hagen M, Knappe RU, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker JC, Rizos T, Volkmann J, Müllges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Rahmig J, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Claßen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Günther A, Hamann GF, Engelhorn T, Lücking H, Dörfler A, Schwab S, Huttner HB.

Stroke. 2019 Jun;50(6):1392-1402. doi: 10.1161/STROKEAHA.118.023492. Epub 2019 May 16.

PMID:
31092170
2.

Heparin for prophylaxis of venous thromboembolism in intracerebral haemorrhage.

Sprügel MI, Sembill JA, Kuramatsu JB, Gerner ST, Hagen M, Roeder SS, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker JC, Rizos T, Volkmann J, Muellges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Wöpking S, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Classen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Guenther A, Hamann GF, Lücking H, Dörfler A, Schwab S, Huttner HB.

J Neurol Neurosurg Psychiatry. 2019 Jul;90(7):783-791. doi: 10.1136/jnnp-2018-319786. Epub 2019 Apr 16.

PMID:
30992334
3.

Proteomic analysis of glycosomes from Trypanosoma cruzi epimastigotes.

Acosta H, Burchmore R, Naula C, Gualdrón-López M, Quintero-Troconis E, Cáceres AJ, Michels PAM, Concepción JL, Quiñones W.

Mol Biochem Parasitol. 2019 Apr;229:62-74. doi: 10.1016/j.molbiopara.2019.02.008. Epub 2019 Mar 1.

PMID:
30831156
4.

Control and regulation of the pyrophosphate-dependent glucose metabolism in Entamoeba histolytica.

Saavedra E, Encalada R, Vázquez C, Olivos-García A, Michels PAM, Moreno-Sánchez R.

Mol Biochem Parasitol. 2019 Apr;229:75-87. doi: 10.1016/j.molbiopara.2019.02.002. Epub 2019 Feb 14. Review.

PMID:
30772421
5.

The kinetic characteristics of human and trypanosomatid phosphofructokinases for the reverse reaction.

Fernandes PM, Kinkead J, McNae IW, Bringaud F, Michels PAM, Walkinshaw MD.

Biochem J. 2019 Jan 18;476(2):179-191. doi: 10.1042/BCJ20180635.

6.

Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosation.

Mitchell AR, Yuan M, Morgan HP, McNae IW, Blackburn EA, Le Bihan T, Homem RA, Yu M, Loake GJ, Michels PA, Wear MA, Walkinshaw MD.

Biochem J. 2018 Oct 31;475(20):3275-3291. doi: 10.1042/BCJ20180556.

7.

Drug Target Selection for Trypanosoma cruzi Metabolism by Metabolic Control Analysis and Kinetic Modeling.

Saavedra E, Gonzalez-Chavez Z, Moreno-Sanchez R, Michels PAM.

Curr Med Chem. 2018 Sep 16. doi: 10.2174/0929867325666180917104242. [Epub ahead of print]

PMID:
30221599
8.

[Recurrence of carotodynia or TIPIC syndrome].

Schaumberg J, Michels P, Eckert B, Röther J.

Nervenarzt. 2018 Dec;89(12):1403-1407. doi: 10.1007/s00115-018-0531-3. German. No abstract available.

PMID:
29767816
9.

An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor.

Yuan M, McNae IW, Chen Y, Blackburn EA, Wear MA, Michels PAM, Fothergill-Gilmore LA, Hupp T, Walkinshaw MD.

Biochem J. 2018 May 31;475(10):1821-1837. doi: 10.1042/BCJ20180171.

10.

The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids.

Marchese L, Nascimento JF, Damasceno FS, Bringaud F, Michels PAM, Silber AM.

Pathogens. 2018 Apr 1;7(2). pii: E36. doi: 10.3390/pathogens7020036. Review.

11.

Enolase from Trypanosoma cruzi is inhibited by its interaction with metallocarboxypeptidase-1 and a putative acireductone dioxygenase.

Quintero-Troconis E, Buelvas N, Carrasco-López C, Domingo-Sananes MR, González-González L, Ramírez-Molina R, Osorio L, Lobo-Rojas A, Cáceres AJ, Michels PA, Acosta H, Quiñones W, Concepción JL.

Biochim Biophys Acta Proteins Proteom. 2018 May - Jun;1866(5-6):651-660. doi: 10.1016/j.bbapap.2018.03.003. Epub 2018 Mar 10.

PMID:
29530564
12.

Management of therapeutic anticoagulation in patients with intracerebral haemorrhage and mechanical heart valves.

Kuramatsu JB, Sembill JA, Gerner ST, Sprügel MI, Hagen M, Roeder SS, Endres M, Haeusler KG, Sobesky J, Schurig J, Zweynert S, Bauer M, Vajkoczy P, Ringleb PA, Purrucker J, Rizos T, Volkmann J, Müllges W, Kraft P, Schubert AL, Erbguth F, Nueckel M, Schellinger PD, Glahn J, Knappe UJ, Fink GR, Dohmen C, Stetefeld H, Fisse AL, Minnerup J, Hagemann G, Rakers F, Reichmann H, Schneider H, Wöpking S, Ludolph AC, Stösser S, Neugebauer H, Röther J, Michels P, Schwarz M, Reimann G, Bäzner H, Schwert H, Claßen J, Michalski D, Grau A, Palm F, Urbanek C, Wöhrle JC, Alshammari F, Horn M, Bahner D, Witte OW, Günther A, Hamann GF, Lücking H, Dörfler A, Achenbach S, Schwab S, Huttner HB.

Eur Heart J. 2018 May 14;39(19):1709-1723. doi: 10.1093/eurheartj/ehy056.

13.

Nanotechnological Strategies for Treatment of Leishmaniasis--A Review.

de Almeida L, Terumi Fujimura A, Del Cistia ML, Fonseca-Santos B, Braga Imamura K, Michels PAM, Chorilli M, Graminha MAS.

J Biomed Nanotechnol. 2017 Feb;13(2):117-33. Review.

PMID:
29376626
14.

A paradigm shift: The mitoproteomes of procyclic and bloodstream Trypanosoma brucei are comparably complex.

Zíková A, Verner Z, Nenarokova A, Michels PAM, Lukeš J.

PLoS Pathog. 2017 Dec 21;13(12):e1006679. doi: 10.1371/journal.ppat.1006679. eCollection 2017 Dec. Review. No abstract available.

15.

Structure and function of Per-ARNT-Sim domains and their possible role in the life-cycle biology of Trypanosoma cruzi.

Rojas-Pirela M, Rigden DJ, Michels PA, Cáceres AJ, Concepción JL, Quiñones W.

Mol Biochem Parasitol. 2018 Jan;219:52-66. doi: 10.1016/j.molbiopara.2017.11.002. Epub 2017 Nov 11. Review.

PMID:
29133150
16.

Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.

Linciano P, Dawson A, Pöhner I, Costa DM, Sá MS, Cordeiro-da-Silva A, Luciani R, Gul S, Witt G, Ellinger B, Kuzikov M, Gribbon P, Reinshagen J, Wolf M, Behrens B, Hannaert V, Michels PAM, Nerini E, Pozzi C, di Pisa F, Landi G, Santarem N, Ferrari S, Saxena P, Lazzari S, Cannazza G, Freitas-Junior LH, Moraes CB, Pascoalino BS, Alcântara LM, Bertolacini CP, Fontana V, Wittig U, Müller W, Wade RC, Hunter WN, Mangani S, Costantino L, Costi MP.

ACS Omega. 2017 Sep 30;2(9):5666-5683. doi: 10.1021/acsomega.7b00473. Epub 2017 Sep 11.

17.

Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition.

Yuan M, Vásquez-Valdivieso MG, McNae IW, Michels PAM, Fothergill-Gilmore LA, Walkinshaw MD.

J Mol Biol. 2017 Oct 13;429(20):3075-3089. doi: 10.1016/j.jmb.2017.08.010. Epub 2017 Sep 4.

18.

[Neurophysiological monitoring during surgical procedures].

Michels P, Bräuer A, Bauer M, Söhle M.

Anaesthesist. 2017 Sep;66(9):645-659. doi: 10.1007/s00101-017-0356-7. Review. German.

PMID:
28840256
19.

Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.

Balogun EO, Inaoka DK, Shiba T, Tokuoka SM, Tokumasu F, Sakamoto K, Kido Y, Michels PAM, Watanabe YI, Harada S, Kita K.

Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2830-2842. doi: 10.1016/j.bbagen.2017.07.028. Epub 2017 Aug 2.

PMID:
28778484
20.

Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1.

Harijan RK, Kiema TR, Syed SM, Qadir I, Mazet M, Bringaud F, Michels PAM, Wierenga RK.

Protein Eng Des Sel. 2017 Mar 1;30(3):225-233. doi: 10.1093/protein/gzw080.

PMID:
28062645
21.

Evaluation of Antigens for Development of a Serological Test for Human African Trypanosomiasis.

Biéler S, Waltenberger H, Barrett MP, McCulloch R, Mottram JC, Carrington M, Schwaeble W, McKerrow J, Phillips MA, Michels PA, Büscher P, Sanchez JC, Bishop R, Robinson DR, Bangs J, Ferguson M, Nerima B, Albertini A, Michel G, Radwandska M, Ndung'u JM.

PLoS One. 2016 Dec 9;11(12):e0168074. doi: 10.1371/journal.pone.0168074. eCollection 2016.

22.

The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism.

Harijan RK, Mazet M, Kiema TR, Bouyssou G, Alexson SE, Bergmann U, Moreau P, Michels PA, Bringaud F, Wierenga RK.

Proteins. 2016 Aug;84(8):1075-96. doi: 10.1002/prot.25054. Epub 2016 May 9.

PMID:
27093562
23.

Trypanosoma evansi contains two auxiliary enzymes of glycolytic metabolism: Phosphoenolpyruvate carboxykinase and pyruvate phosphate dikinase.

Rivero LA, Concepción JL, Quintero-Troconis E, Quiñones W, Michels PA, Acosta H.

Exp Parasitol. 2016 Jun;165:7-15. doi: 10.1016/j.exppara.2016.03.003. Epub 2016 Mar 9.

PMID:
26968775
24.

Peroxisomes in parasitic protists.

Gabaldón T, Ginger ML, Michels PA.

Mol Biochem Parasitol. 2016 Sep - Oct;209(1-2):35-45. doi: 10.1016/j.molbiopara.2016.02.005. Epub 2016 Feb 16. Review.

PMID:
26896770
25.

Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites.

Haanstra JR, González-Marcano EB, Gualdrón-López M, Michels PA.

Biochim Biophys Acta. 2016 May;1863(5):1038-48. doi: 10.1016/j.bbamcr.2015.09.015. Epub 2015 Sep 16. Review.

26.

Clopidogrel Resistance in Neurovascular Stenting: Correlations between Light Transmission Aggregometry, VerifyNow, and the Multiplate.

Flechtenmacher N, Kämmerer F, Dittmer R, Budde U, Michels P, Röther J, Eckert B.

AJNR Am J Neuroradiol. 2015 Oct;36(10):1953-8. doi: 10.3174/ajnr.A4388. Epub 2015 Aug 13.

27.

ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei.

Brennand A, Rico E, Rigden DJ, Van Der Smissen P, Courtoy PJ, Michels PA.

PLoS One. 2015 Jun 19;10(6):e0130365. doi: 10.1371/journal.pone.0130365. eCollection 2015.

28.

Structures of pyruvate kinases display evolutionarily divergent allosteric strategies.

Morgan HP, Zhong W, McNae IW, Michels PA, Fothergill-Gilmore LA, Walkinshaw MD.

R Soc Open Sci. 2014 Sep 24;1(1):140120. doi: 10.1098/rsos.140120. eCollection 2014 Sep.

29.

Synthesis and evaluation of novel prenylated chalcone derivatives as anti-leishmanial and anti-trypanosomal compounds.

Passalacqua TG, Dutra LA, de Almeida L, Velásquez AM, Torres FA, Yamasaki PR, dos Santos MB, Regasini LO, Michels PA, Bolzani Vda S, Graminha MA.

Bioorg Med Chem Lett. 2015 Aug 15;25(16):3342-5. doi: 10.1016/j.bmcl.2015.05.072. Epub 2015 May 30.

PMID:
26055530
30.

The glycosomal-membrane associated phosphoglycerate kinase isoenzyme A plays a role in sustaining the glucose flux in Trypanosoma cruzi epimastigotes.

Barros-Álvarez X, Cáceres AJ, Ruiz MT, Michels PA, Concepción JL, Quiñones W.

Mol Biochem Parasitol. 2015 Mar-Apr;200(1-2):5-8. doi: 10.1016/j.molbiopara.2015.04.003. Epub 2015 Apr 25.

PMID:
25917939
31.

Lead optimization toward proof-of-concept tools for Huntington's disease within a 4-(1H-pyrazol-4-yl)pyrimidine class of pan-JNK inhibitors.

Wityak J, McGee KF, Conlon MP, Song RH, Duffy BC, Clayton B, Lynch M, Wang G, Freeman E, Haber J, Kitchen DB, Manning DD, Ismail J, Khmelnitsky Y, Michels P, Webster J, Irigoyen M, Luche M, Hultman M, Bai M, Kuok ID, Newell R, Lamers M, Leonard P, Yates D, Matthews K, Ongeri L, Clifton S, Mead T, Deupree S, Wheelan P, Lyons K, Wilson C, Kiselyov A, Toledo-Sherman L, Beconi M, Muñoz-Sanjuan I, Bard J, Dominguez C.

J Med Chem. 2015 Apr 9;58(7):2967-87. doi: 10.1021/jm5013598. Epub 2015 Mar 19.

PMID:
25760409
32.

Anticoagulant reversal, blood pressure levels, and anticoagulant resumption in patients with anticoagulation-related intracerebral hemorrhage.

Kuramatsu JB, Gerner ST, Schellinger PD, Glahn J, Endres M, Sobesky J, Flechsenhar J, Neugebauer H, Jüttler E, Grau A, Palm F, Röther J, Michels P, Hamann GF, Hüwel J, Hagemann G, Barber B, Terborg C, Trostdorf F, Bäzner H, Roth A, Wöhrle J, Keller M, Schwarz M, Reimann G, Volkmann J, Müllges W, Kraft P, Classen J, Hobohm C, Horn M, Milewski A, Reichmann H, Schneider H, Schimmel E, Fink GR, Dohmen C, Stetefeld H, Witte O, Günther A, Neumann-Haefelin T, Racs AE, Nueckel M, Erbguth F, Kloska SP, Dörfler A, Köhrmann M, Schwab S, Huttner HB.

JAMA. 2015 Feb 24;313(8):824-36. doi: 10.1001/jama.2015.0846.

PMID:
25710659
33.

[Hot topics in neuroanesthesiology : Three important publications in 2013 and 2014].

Michels P, Schneider G, Crozier TA.

Anaesthesist. 2015 Feb;64(2):152-8. doi: 10.1007/s00101-014-2411-y. German. No abstract available.

PMID:
25523322
34.

In or out? On the tightness of glycosomal compartmentalization of metabolites and enzymes in Trypanosoma brucei.

Haanstra JR, Bakker BM, Michels PA.

Mol Biochem Parasitol. 2014 Nov;198(1):18-28. doi: 10.1016/j.molbiopara.2014.11.004. Epub 2014 Dec 2. Review.

PMID:
25476771
35.

Evolution, dynamics and specialized functions of glycosomes in metabolism and development of trypanosomatids.

Szöör B, Haanstra JR, Gualdrón-López M, Michels PA.

Curr Opin Microbiol. 2014 Dec;22:79-87. doi: 10.1016/j.mib.2014.09.006. Review.

PMID:
25460800
36.

Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.

Balogun EO, Inaoka DK, Shiba T, Kido Y, Tsuge C, Nara T, Aoki T, Honma T, Tanaka A, Inoue M, Matsuoka S, Michels PA, Kita K, Harada S.

Mol Microbiol. 2014 Dec;94(6):1315-29. doi: 10.1111/mmi.12831. Epub 2014 Nov 4.

37.

TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.

Shameer S, Logan-Klumpler FJ, Vinson F, Cottret L, Merlet B, Achcar F, Boshart M, Berriman M, Breitling R, Bringaud F, Bütikofer P, Cattanach AM, Bannerman-Chukualim B, Creek DJ, Crouch K, de Koning HP, Denise H, Ebikeme C, Fairlamb AH, Ferguson MA, Ginger ML, Hertz-Fowler C, Kerkhoven EJ, Mäser P, Michels PA, Nayak A, Nes DW, Nolan DP, Olsen C, Silva-Franco F, Smith TK, Taylor MC, Tielens AG, Urbaniak MD, van Hellemond JJ, Vincent IM, Wilkinson SR, Wyllie S, Opperdoes FR, Barrett MP, Jourdan F.

Nucleic Acids Res. 2015 Jan;43(Database issue):D637-44. doi: 10.1093/nar/gku944. Epub 2014 Oct 9.

38.

The Power of Hybrid/Fusion Imaging Metrics in Future PACS Systems: A Case Study into the White Matter Hyperintensity Prenumbra using FLAIR and Diffusion MR.

Tsao S, Ma SJ, Michels PA, Gajawelli N, Law M, Chui H, Lepore N.

Proc SPIE Int Soc Opt Eng. 2014 Apr 9;9039:90390I.

39.

Trypanosomatid phosphoglycerate mutases have multiple conformational and oligomeric states.

Blackburn EA, Fuad FA, Morgan HP, Nowicki MW, Wear MA, Michels PA, Fothergill-Gilmore LA, Walkinshaw MD.

Biochem Biophys Res Commun. 2014 Jul 25;450(2):936-41. doi: 10.1016/j.bbrc.2014.06.113. Epub 2014 Jun 28.

PMID:
24984149
40.

Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase.

Brimacombe KR, Walsh MJ, Liu L, Vásquez-Valdivieso MG, Morgan HP, McNae I, Fothergill-Gilmore LA, Michels PA, Auld DS, Simeonov A, Walkinshaw MD, Shen M, Boxer MB.

ACS Med Chem Lett. 2013 Oct 30;5(1):12-7. doi: 10.1021/ml400259d. eCollection 2014 Jan 9.

41.

The phosphoglycerate kinase isoenzymes have distinct roles in the regulation of carbohydrate metabolism in Trypanosoma cruzi.

Barros-Álvarez X, Cáceres AJ, Michels PA, Concepción JL, Quiñones W.

Exp Parasitol. 2014 Aug;143:39-47. doi: 10.1016/j.exppara.2014.05.010. Epub 2014 May 20.

PMID:
24858924
42.

Phylogenetic relationships and classification of thiolases and thiolase-like proteins of Mycobacterium tuberculosis and Mycobacterium smegmatis.

Anbazhagan P, Harijan RK, Kiema TR, Janardan N, Murthy MR, Michels PA, Juffer AH, Wierenga RK.

Tuberculosis (Edinb). 2014 Jul;94(4):405-12. doi: 10.1016/j.tube.2014.03.003. Epub 2014 Apr 4.

PMID:
24825023
43.

Extracellular functions of glycolytic enzymes of parasites: unpredicted use of ancient proteins.

Gómez-Arreaza A, Acosta H, Quiñones W, Concepción JL, Michels PA, Avilán L.

Mol Biochem Parasitol. 2014 Feb;193(2):75-81. doi: 10.1016/j.molbiopara.2014.02.005. Epub 2014 Mar 3. Review.

PMID:
24602601
44.

[Quality assurance at the interface between anesthesia and transfusion medicine].

Waeschle RM, Michels P, Jipp M, Riech S, Schulze T, Schmidt CE, Bauer M.

Anaesthesist. 2014 Feb;63(2):154-62. doi: 10.1007/s00101-013-2284-5. German.

PMID:
24469248
45.

Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against Trypanosoma brucei and Trypanosoma cruzi.

Belluti F, Uliassi E, Veronesi G, Bergamini C, Kaiser M, Brun R, Viola A, Fato R, Michels PA, Krauth-Siegel RL, Cavalli A, Bolognesi ML.

ChemMedChem. 2014 Feb;9(2):371-82. doi: 10.1002/cmdc.201300399. Epub 2014 Jan 8.

PMID:
24403089
46.

Pyruvate kinases have an intrinsic and conserved decarboxylase activity.

Zhong W, Morgan HP, Nowicki MW, McNae IW, Yuan M, Bella J, Michels PA, Fothergill-Gilmore LA, Walkinshaw MD.

Biochem J. 2014 Mar 1;458(2):301-11. doi: 10.1042/BJ20130790.

47.

Identification of Selective Inhibitors of Phosphofructokinase as Lead Compounds Against Trypanosomiasis.

Walsh MJ, Brimacombe KR, Vásquez-Valdivieso MG, Auld DS, Simeonov A, Morgan HP, Fothergill-Gilmore LA, Michels PAM, Walkinshaw MD, Shen M, Boxer MB.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Oct 18 [updated 2013 Feb 25].

48.

`In crystallo' substrate binding triggers major domain movements and reveals magnesium as a co-activator of Trypanosoma brucei pyruvate kinase.

Zhong W, Morgan HP, McNae IW, Michels PA, Fothergill-Gilmore LA, Walkinshaw MD.

Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1768-79. doi: 10.1107/S0907444913013875. Epub 2013 Aug 17.

PMID:
23999300
49.

Ubiquitination of the glycosomal matrix protein receptor PEX5 in Trypanosoma brucei by PEX4 displays novel features.

Gualdrón-López M, Chevalier N, Van Der Smissen P, Courtoy PJ, Rigden DJ, Michels PAM.

Biochim Biophys Acta. 2013 Dec;1833(12):3076-3092. doi: 10.1016/j.bbamcr.2013.08.008. Epub 2013 Aug 27.

50.

Crystal structures of SCP2-thiolases of Trypanosomatidae, human pathogens causing widespread tropical diseases: the importance for catalysis of the cysteine of the unique HDCF loop.

Harijan RK, Kiema TR, Karjalainen MP, Janardan N, Murthy MR, Weiss MS, Michels PA, Wierenga RK.

Biochem J. 2013 Oct 1;455(1):119-30. doi: 10.1042/BJ20130669.

PMID:
23909465

Supplemental Content

Loading ...
Support Center