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Items: 19


Hexim1, an RNA-controlled protein hub.

Michels AA, Bensaude O.

Transcription. 2018;9(4):262-271. doi: 10.1080/21541264.2018.1429836. Epub 2018 Feb 23. Review.


Immunosuppressive therapy after solid-organ transplantation: does the INTERMED identify patients at risk of poor adherence?

Michaud L, Ludwig G, Berney S, Rodrigues S, Niquille A, Santschi V, Favre AS, Lange AC, Michels AA, Vrijens B, Bugnon O, Pilon N, Pascual M, Venetz JP, Stiefel F, Schneider MP.

Pharm Pract (Granada). 2016 Oct-Dec;14(4):822. doi: 10.18549/PharmPract.2016.04.822. Epub 2016 Dec 15.


Broadening the spectrum of β-lactam antibiotics through inhibition of signal peptidase type I.

Therien AG, Huber JL, Wilson KE, Beaulieu P, Caron A, Claveau D, Deschamps K, Donald RG, Galgoci AM, Gallant M, Gu X, Kevin NJ, Lafleur J, Leavitt PS, Lebeau-Jacob C, Lee SS, Lin MM, Michels AA, Ogawa AM, Painter RE, Parish CA, Park YW, Benton-Perdomo L, Petcu M, Phillips JW, Powles MA, Skorey KI, Tam J, Tan CM, Young K, Wong S, Waddell ST, Miesel L.

Antimicrob Agents Chemother. 2012 Sep;56(9):4662-70. doi: 10.1128/AAC.00726-12. Epub 2012 Jun 18.


MAF1: a new target of mTORC1.

Michels AA.

Biochem Soc Trans. 2011 Apr;39(2):487-91. doi: 10.1042/BST0390487. Review.


mTORC1 directly phosphorylates and regulates human MAF1.

Michels AA, Robitaille AM, Buczynski-Ruchonnet D, Hodroj W, Reina JH, Hall MN, Hernandez N.

Mol Cell Biol. 2010 Aug;30(15):3749-57. doi: 10.1128/MCB.00319-10. Epub 2010 Jun 1.


Ubiquitination of HEXIM1 by HDM2.

Lau J, Lew QJ, Diribarne G, Michels AA, Dey A, Bensaude O, Lane DP, Chao SH.

Cell Cycle. 2009 Jul 15;8(14):2247-54.


RNA-driven cyclin-dependent kinase regulation: when CDK9/cyclin T subunits of P-TEFb meet their ribonucleoprotein partners.

Michels AA, Bensaude O.

Biotechnol J. 2008 Aug;3(8):1022-32. doi: 10.1002/biot.200800104. Review.


Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I.

Bierhoff H, Dundr M, Michels AA, Grummt I.

Mol Cell Biol. 2008 Aug;28(16):4988-98. doi: 10.1128/MCB.00492-08. Epub 2008 Jun 16.


Does Pol I talk to Pol II? Coordination of RNA polymerases in ribosome biogenesis.

Michels AA, Hernandez N.

Genes Dev. 2006 Aug 1;20(15):1982-5. No abstract available.


Transcription-dependent association of multiple positive transcription elongation factor units to a HEXIM multimer.

Dulac C, Michels AA, Fraldi A, Bonnet F, Nguyen VT, Napolitano G, Lania L, Bensaude O.

J Biol Chem. 2005 Aug 26;280(34):30619-29. Epub 2005 Jun 30.


Inhibition of Tat activity by the HEXIM1 protein.

Fraldi A, Varrone F, Napolitano G, Michels AA, Majello B, Bensaude O, Lania L.

Retrovirology. 2005 Jul 2;2:42.


Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor.

Michels AA, Fraldi A, Li Q, Adamson TE, Bonnet F, Nguyen VT, Sedore SC, Price JP, Price DH, Lania L, Bensaude O.

EMBO J. 2004 Jul 7;23(13):2608-19. Epub 2004 Jun 17.


MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner.

Michels AA, Nguyen VT, Fraldi A, Labas V, Edwards M, Bonnet F, Lania L, Bensaude O.

Mol Cell Biol. 2003 Jul;23(14):4859-69. Erratum in: Mol Cell Biol. 2003 Dec;23(24):9405.


7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes.

Nguyen VT, Kiss T, Michels AA, Bensaude O.

Nature. 2001 Nov 15;414(6861):322-5.


Cycloheximide- and puromycin-induced heat resistance: different effects on cytoplasmic and nuclear luciferases.

Michels AA, Kanon B, Konings AW, Bensaude O, Kampinga HH.

Cell Stress Chaperones. 2000 Jul;5(3):181-7.


Heat shock protein (Hsp) 40 mutants inhibit Hsp70 in mammalian cells.

Michels AA, Kanon B, Bensaude O, Kampinga HH.

J Biol Chem. 1999 Dec 17;274(51):36757-63.


Hsp70 and Hsp40 chaperone activities in the cytoplasm and the nucleus of mammalian cells.

Michels AA, Kanon B, Konings AW, Ohtsuka K, Bensaude O, Kampinga HH.

J Biol Chem. 1997 Dec 26;272(52):33283-9.


Thermostability of a nuclear-targeted luciferase expressed in mammalian cells. Destabilizing influence of the intranuclear microenvironment.

Michels AA, Nguyen VT, Konings AW, Kampinga HH, Bensaude O.

Eur J Biochem. 1995 Dec 1;234(2):382-9.


Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-src oncogene product.

Ottenhoff-Kalff AE, Rijksen G, van Beurden EA, Hennipman A, Michels AA, Staal GE.

Cancer Res. 1992 Sep 1;52(17):4773-8.

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