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Items: 15

1.

T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis.

Cataisson C, Salcedo R, Michalowski AM, Klosterman M, Naik S, Li L, Pan MJ, Sweet A, Chen JQ, Kostecka LG, Karwan M, Smith L, Dai RM, Stewart CA, Lyakh L, Hsieh WT, Khan A, Yang H, Lee M, Trinchieri G, Yuspa SH.

Mol Cancer Res. 2019 Aug;17(8):1759-1773. doi: 10.1158/1541-7786.MCR-19-0227. Epub 2019 Jun 4.

PMID:
31164412
2.

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.

Calabrese DR, Chen X, Leon EC, Gaikwad SM, Phyo Z, Hewitt WM, Alden S, Hilimire TA, He F, Michalowski AM, Simmons JK, Saunders LB, Zhang S, Connors D, Walters KJ, Mock BA, Schneekloth JS Jr.

Nat Commun. 2018 Oct 12;9(1):4229. doi: 10.1038/s41467-018-06315-w.

3.

Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation.

Simmons JK, Michalowski AM, Gamache BJ, DuBois W, Patel J, Zhang K, Gary J, Zhang S, Gaikwad S, Connors D, Watson N, Leon E, Chen JQ, Kuehl WM, Lee MP, Zingone A, Landgren O, Ordentlich P, Huang J, Mock BA.

Mol Cancer Ther. 2017 Sep;16(9):2008-2021. doi: 10.1158/1535-7163.MCT-17-0171. Epub 2017 May 18.

4.

MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.

Cataisson C, Michalowski AM, Shibuya K, Ryscavage A, Klosterman M, Wright L, Dubois W, Liu F, Zhuang A, Rodrigues KB, Hoover S, Dwyer J, Simpson MR, Merlino G, Yuspa SH.

Sci Signal. 2016 Jun 21;9(433):ra62. doi: 10.1126/scisignal.aaf5106.

5.

An in vitro priming step increases the expression of numerous epidermal growth and migration mediators in a tissue-engineering construct.

Lin X, Kwak T, Fiore D, Thompson PJ, Goodrich JK, Yufit T, Michalowski AM, Deschenes J, Carson P, Otero-Vinas M, Falanga V.

J Tissue Eng Regen Med. 2017 Mar;11(3):713-723. doi: 10.1002/term.1967. Epub 2014 Dec 26.

PMID:
25546487
6.

An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer.

Sato M, Kadota M, Tang B, Yang HH, Yang YA, Shan M, Weng J, Welsh MA, Flanders KC, Nagano Y, Michalowski AM, Clifford RJ, Lee MP, Wakefield LM.

Breast Cancer Res. 2014 Jun 2;16(3):R57. doi: 10.1186/bcr3668.

7.

Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogs in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action.

Kedei N, Telek A, Michalowski AM, Kraft MB, Li W, Poudel YB, Rudra A, Petersen ME, Keck GE, Blumberg PM.

Biochem Pharmacol. 2013 Feb 1;85(3):313-24. doi: 10.1016/j.bcp.2012.10.028. Epub 2012 Nov 9.

8.

Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer.

Bennett CN, Tomlinson CC, Michalowski AM, Chu IM, Luger D, Mittereder LR, Aprelikova O, Shou J, Piwinica-Worms H, Caplen NJ, Hollingshead MG, Green JE.

Breast Cancer Res. 2012 Jul 19;14(4):R109. doi: 10.1186/bcr3230.

9.

Investigation into diagnostic agreement using automated computer-assisted histopathology pattern recognition image analysis.

Webster JD, Michalowski AM, Dwyer JE, Corps KN, Wei BR, Juopperi T, Hoover SB, Simpson RM.

J Pathol Inform. 2012;3:18. doi: 10.4103/2153-3539.95130. Epub 2012 Apr 18.

10.
11.

GATA3 inhibits lysyl oxidase-mediated metastases of human basal triple-negative breast cancer cells.

Chu IM, Michalowski AM, Hoenerhoff M, Szauter KM, Luger D, Sato M, Flanders K, Oshima A, Csiszar K, Green JE.

Oncogene. 2012 Apr 19;31(16):2017-27. doi: 10.1038/onc.2011.382. Epub 2011 Sep 5.

12.

RasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanoma.

Yang D, Tao J, Li L, Kedei N, Tóth ZE, Czap A, Velasquez JF, Mihova D, Michalowski AM, Yuspa SH, Blumberg PM.

Oncogene. 2011 Nov 10;30(45):4590-4600. doi: 10.1038/onc.2011.166. Epub 2011 May 23.

13.

RasGRP3 contributes to formation and maintenance of the prostate cancer phenotype.

Yang D, Kedei N, Li L, Tao J, Velasquez JF, Michalowski AM, Tóth BI, Marincsák R, Varga A, Bíró T, Yuspa SH, Blumberg PM.

Cancer Res. 2010 Oct 15;70(20):7905-17. doi: 10.1158/0008-5472.CAN-09-4729. Epub 2010 Sep 28.

14.

Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment.

Barkan D, El Touny LH, Michalowski AM, Smith JA, Chu I, Davis AS, Webster JD, Hoover S, Simpson RM, Gauldie J, Green JE.

Cancer Res. 2010 Jul 15;70(14):5706-16. doi: 10.1158/0008-5472.CAN-09-2356. Epub 2010 Jun 22.

15.

A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells.

Lee KH, Li M, Michalowski AM, Zhang X, Liao H, Chen L, Xu Y, Wu X, Huang J.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):69-74. doi: 10.1073/pnas.0909734107. Epub 2009 Dec 14.

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