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Items: 1 to 50 of 73

1.

High-throughput smFRET analysis of freely diffusing nucleic acid molecules and associated proteins.

Segal M, Ingargiola A, Lerner E, Chung S, White JA, Streets A, Weiss S, Michalet X.

Methods. 2019 Jul 26. pii: S1046-2023(18)30443-2. doi: 10.1016/j.ymeth.2019.07.021. [Epub ahead of print]

PMID:
31356875
2.

Optical crosstalk in SPAD arrays for high-throughput single-molecule fluorescence spectroscopy.

Ingargiola A, Segal M, Gulinatti A, Rech I, Labanca I, Maccagnani P, Ghioni M, Weiss S, Michalet X.

Nucl Instrum Methods Phys Res A. 2018 Dec 21;9(12):255-258. doi: 10.1016/j.nima.2017.11.070. Epub 2017 Nov 24.

3.

A 512×512 SPAD Image Sensor with Integrated Gating for Widefield FLIM.

Ulku AC, Bruschini C, Antolovic IM, Charbon E, Kuo Y, Ankri R, Weiss S, Michalet X.

IEEE J Sel Top Quantum Electron. 2019 Jan-Feb;25(1). pii: 6801212. doi: 10.1109/JSTQE.2018.2867439. Epub 2018 Aug 28.

PMID:
31156324
4.

In vitro and in vivo phasor analysis of stoichiometry and pharmacokinetics using short-lifetime near-infrared dyes and time-gated imaging.

Chen SJ, Sinsuebphon N, Rudkouskaya A, Barroso M, Intes X, Michalet X.

J Biophotonics. 2019 Mar;12(3):e201800185. doi: 10.1002/jbio.201800185. Epub 2018 Dec 9.

PMID:
30421551
5.

48-spot single-molecule FRET setup with periodic acceptor excitation.

Ingargiola A, Segal M, Gulinatti A, Rech I, Labanca I, Maccagnani P, Ghioni M, Weiss S, Michalet X.

J Chem Phys. 2018 Mar 28;148(12):123304. doi: 10.1063/1.5000742.

6.

Toward dynamic structural biology: Two decades of single-molecule Förster resonance energy transfer.

Lerner E, Cordes T, Ingargiola A, Alhadid Y, Chung S, Michalet X, Weiss S.

Science. 2018 Jan 19;359(6373). pii: eaan1133. doi: 10.1126/science.aan1133. Review.

7.

16-Ch Time-resolved Single-Molecule Spectroscopy Using Line Excitation.

Ingargiola A, Peronio P, Lerner E, Gulinatti A, Rech I, Ghioni M, Weiss S, Michalet X.

Proc SPIE Int Soc Opt Eng. 2017 Jan 28;10071. pii: 100710Q. doi: 10.1117/12.2256367. Epub 2017 Mar 2.

8.

Multispot single-molecule FRET: High-throughput analysis of freely diffusing molecules.

Ingargiola A, Lerner E, Chung S, Panzeri F, Gulinatti A, Rech I, Ghioni M, Weiss S, Michalet X.

PLoS One. 2017 Apr 18;12(4):e0175766. doi: 10.1371/journal.pone.0175766. eCollection 2017.

9.

Different types of pausing modes during transcription initiation.

Lerner E, Ingargiola A, Lee JJ, Borukhov S, Michalet X, Weiss S.

Transcription. 2017 Aug 8;8(4):242-253. doi: 10.1080/21541264.2017.1308853. Epub 2017 Mar 23.

10.

Backtracked and paused transcription initiation intermediate of Escherichia coli RNA polymerase.

Lerner E, Chung S, Allen BL, Wang S, Lee J, Lu SW, Grimaud LW, Ingargiola A, Michalet X, Alhadid Y, Borukhov S, Strick TR, Taatjes DJ, Weiss S.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6562-E6571. Epub 2016 Oct 11.

11.

FRETBursts: An Open Source Toolkit for Analysis of Freely-Diffusing Single-Molecule FRET.

Ingargiola A, Lerner E, Chung S, Weiss S, Michalet X.

PLoS One. 2016 Aug 17;11(8):e0160716. doi: 10.1371/journal.pone.0160716. eCollection 2016.

12.

Photon-HDF5: Open Data Format and Computational Tools for Timestamp-based Single-Molecule Experiments.

Ingargiola A, Laurence T, Boutelle R, Weiss S, Michalet X.

Proc SPIE Int Soc Opt Eng. 2016 Feb 13;9714. pii: 971405. doi: 10.1117/12.2212085. Epub 2016 Mar 1.

13.

Photon-HDF5: An Open File Format for Timestamp-Based Single-Molecule Fluorescence Experiments.

Ingargiola A, Laurence T, Boutelle R, Weiss S, Michalet X.

Biophys J. 2016 Jan 5;110(1):26-33. doi: 10.1016/j.bpj.2015.11.013.

14.

Silicon photon-counting avalanche diodes for single-molecule fluorescence spectroscopy.

Michalet X, Ingargiola A, Colyer RA, Scalia G, Weiss S, Maccagnani P, Gulinatti A, Rech I, Ghioni M.

IEEE J Sel Top Quantum Electron. 2014 Nov;20(6):38044201-380442020.

15.

Architecture and applications of a high resolution gated SPAD image sensor.

Burri S, Maruyama Y, Michalet X, Regazzoni F, Bruschini C, Charbon E.

Opt Express. 2014 Jul 14;22(14):17573-89. doi: 10.1364/OE.22.017573.

16.

A 65k pixel, 150k frames-per-second camera with global gating and micro-lenses suitable for fluorescence lifetime imaging.

Burri S, Powolny F, Bruschini C, Michalet X, Regazzoni F, Charbon E.

Proc SPIE Int Soc Opt Eng. 2014 Apr 14;9141. pii: 914109. doi: 10.1117/12.2052862. Epub 2014 May 15.

17.

8-spot smFRET analysis using two 8-pixel SPAD arrays.

Ingargiola A, Panzeri F, Sarkosh N, Gulinatti A, Rech I, Ghioni M, Weiss S, Michalet X.

Proc SPIE Int Soc Opt Eng. 2013 Feb 22;8590. doi: 10.1117/12.2003704.

18.

Single-molecule FRET experiments with a red-enhanced custom technology SPAD.

Panzeri F, Ingargiola A, Lin RR, Sarkhosh N, Gulinatti A, Rech I, Ghioni M, Cova S, Weiss S, Michalet X.

Proc SPIE Int Soc Opt Eng. 2013 Feb 2;8590. doi: 10.1117/12.2003187.

19.

Toward single-molecule optical mapping of the epigenome.

Levy-Sakin M, Grunwald A, Kim S, Gassman NR, Gottfried A, Antelman J, Kim Y, Ho SO, Samuel R, Michalet X, Lin RR, Dertinger T, Kim AS, Chung S, Colyer RA, Weinhold E, Weiss S, Ebenstein Y.

ACS Nano. 2014 Jan 28;8(1):14-26. doi: 10.1021/nn4050694. Epub 2013 Dec 20.

20.

Development of new photon-counting detectors for single-molecule fluorescence microscopy.

Michalet X, Colyer RA, Scalia G, Ingargiola A, Lin R, Millaud JE, Weiss S, Siegmund OH, Tremsin AS, Vallerga JV, Cheng A, Levi M, Aharoni D, Arisaka K, Villa F, Guerrieri F, Panzeri F, Rech I, Gulinatti A, Zappa F, Ghioni M, Cova S.

Philos Trans R Soc Lond B Biol Sci. 2012 Dec 24;368(1611):20120035. doi: 10.1098/rstb.2012.0035. Print 2013 Feb 5. Review.

21.

Optimal diffusion coefficient estimation in single-particle tracking.

Michalet X, Berglund AJ.

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Jun;85(6 Pt 1):061916. Epub 2012 Jun 21.

22.

Phasor imaging with a widefield photon-counting detector.

Colyer RA, Siegmund OH, Tremsin AS, Vallerga JV, Weiss S, Michalet X.

J Biomed Opt. 2012 Jan;17(1):016008. doi: 10.1117/1.JBO.17.1.016008.

23.

Parallel multispot smFRET analysis using an 8-pixel SPAD array.

Ingargiola A, Colyer RA, Kim D, Panzeri F, Lin R, Gulinatti A, Rech I, Ghioni M, Weiss S, Michalet X.

Proc SPIE Int Soc Opt Eng. 2012 Jan 21;8228. doi: 10.1117/12.909470.

24.

New photon-counting detectors for single-molecule fluorescence spectroscopy and imaging.

Michalet X, Colyer RA, Scalia G, Weiss S, Siegmund OH, Tremsin AS, Vallerga JV, Villa F, Guerrieri F, Rech I, Gulinatti A, Tisa S, Zappa F, Ghioni M, Cova S.

Proc SPIE Int Soc Opt Eng. 2011 May 13;8033:803316.

25.

Microchannel Plate Imaging Photon Counters for Ultraviolet through NIR Detection with High Time Resolution.

Siegmund OH, Vallerga JV, Tremsin AS, McPhate J, Michalet X, Colyer RA, Weiss S.

Proc SPIE Int Soc Opt Eng. 2011 May 12;8033:1350904.

26.

Ultra high-throughput single molecule spectroscopy with a 1024 pixel SPAD.

Colyer RA, Scalia G, Villa FA, Guerrieri F, Tisa S, Zappa F, Cova S, Weiss S, Michalet X.

Proc SPIE Int Soc Opt Eng. 2011 Feb 28;7905. doi: 10.1117/12.874238.

27.

High-throughput FCS using an LCOS spatial light modulator and an 8 × 1 SPAD array.

Colyer RA, Scalia G, Rech I, Gulinatti A, Ghioni M, Cova S, Weiss S, Michalet X.

Biomed Opt Express. 2010 Nov 15;1(5):1408-1431.

28.

Mean square displacement analysis of single-particle trajectories with localization error: Brownian motion in an isotropic medium.

Michalet X.

Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Oct;82(4 Pt 1):041914. Epub 2010 Oct 20.

29.

Tracking single proteins in live cells using single-chain antibody fragment-fluorescent quantum dot affinity pair.

Iyer G, Michalet X, Chang YP, Weiss S.

Methods Enzymol. 2010;475:61-79. doi: 10.1016/S0076-6879(10)75003-5.

30.

High Speed Multichannel Charge Sensitive Data Acquisition System with Self-Triggered Event Timing.

Tremsin AS, Siegmund OH, Vallerga JV, Raffanti R, Weiss S, Michalet X.

IEEE Trans Nucl Sci. 2009 Jun 16;56(3):1148-1152.

31.

Suppression of quantum dot blinking in DTT-doped polymer films.

Antelman J, Ebenstein Y, Dertinger T, Michalet X, Weiss S.

J Phys Chem C Nanomater Interfaces. 2009 Mar 31;113(27):11541-11545.

32.

High-throughput single-molecule fluorescence spectroscopy using parallel detection.

Michalet X, Colyer RA, Scalia G, Kim T, Levi M, Aharoni D, Cheng A, Guerrieri F, Arisaka K, Millaud J, Rech I, Resnati D, Marangoni S, Gulinatti A, Ghioni M, Tisa S, Zappa F, Cova S, Weiss S.

Proc SPIE Int Soc Opt Eng. 2010 Jan 24;7608(76082D). pii: 76082D_1.

33.

High-throughput multispot single-molecule spectroscopy.

Colyer RA, Scalia G, Kim T, Rech I, Resnati D, Marangoni S, Ghioni M, Cova S, Weiss S, Michalet X.

Proc SPIE Int Soc Opt Eng. 2010 Jan 23;7571:75710G-75710G11.

34.

Single-quantum dot imaging with a photon counting camera.

Michalet X, Colyer RA, Antelman J, Siegmund OH, Tremsin A, Vallerga JV, Weiss S.

Curr Pharm Biotechnol. 2009 Aug;10(5):543-58.

35.

Dynamic partitioning of a glycosyl-phosphatidylinositol-anchored protein in glycosphingolipid-rich microdomains imaged by single-quantum dot tracking.

Pinaud F, Michalet X, Iyer G, Margeat E, Moore HP, Weiss S.

Traffic. 2009 Jun;10(6):691-712. doi: 10.1111/j.1600-0854.2009.00902.x. Epub 2009 Mar 27.

36.

Nanometer distance measurements between multicolor quantum dots.

Antelman J, Wilking-Chang C, Weiss S, Michalet X.

Nano Lett. 2009 May;9(5):2199-205. doi: 10.1021/nl901163k.

37.

Lighting up individual DNA binding proteins with quantum dots.

Ebenstein Y, Gassman N, Kim S, Antelman J, Kim Y, Ho S, Samuel R, Michalet X, Weiss S.

Nano Lett. 2009 Apr;9(4):1598-603. doi: 10.1021/nl803820b.

38.

Phasor-based single-molecule fluorescence lifetime imaging using a wide-field photon-counting detector.

Colyer R, Siegmund O, Tremsin A, Vallerga J, Weiss S, Michalet X.

Proc SPIE Int Soc Opt Eng. 2009 Jan 24;7185(71850T). pii: 71850T_1.

39.

High affinity scFv-hapten pair as a tool for quantum dot labeling and tracking of single proteins in live cells.

Iyer G, Michalet X, Chang YP, Pinaud FF, Matyas SE, Payne G, Weiss S.

Nano Lett. 2008 Dec;8(12):4618-23. doi: 10.1021/nl8032284.

40.

Measuring diffusion with polarization-modulation dual-focus fluorescence correlation spectroscopy.

Korlann Y, Dertinger T, Michalet X, Weiss S, Enderlein J.

Opt Express. 2008 Sep 15;16(19):14609-16.

41.

Hybrid photodetector for single-molecule spectroscopy and microscopy.

Michalet X, Cheng A, Antelman J, Suyama M, Arisaka K, Weiss S.

Proc SPIE Int Soc Opt Eng. 2008 Feb 15;6862(68620F). pii: 68620F_1.

42.

Equilibrium shape degeneracy in starfish vesicles.

Michalet X.

Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Aug;76(2 Pt 1):021914. Epub 2007 Aug 10.

PMID:
17930072
43.

Periodic acceptor excitation spectroscopy of single molecules.

Doose S, Heilemann M, Michalet X, Weiss S, Kapanidis AN.

Eur Biophys J. 2007 Jul;36(6):669-74. Epub 2007 Feb 6.

44.

Detectors for single-molecule fluorescence imaging and spectroscopy.

Michalet X, Siegmund OH, Vallerga JV, Jelinsky P, Millaud JE, Weiss S.

J Mod Opt. 2007 Jan 1;54(2-3):239.

45.

Peptide coated quantum dots for biological applications.

Iyer G, Pinaud F, Tsay J, Li JJ, Bentolila LA, Michalet X, Weiss S.

IEEE Trans Nanobioscience. 2006 Dec;5(4):231-8. Review.

46.

Shot-noise limited single-molecule FRET histograms: comparison between theory and experiments.

Nir E, Michalet X, Hamadani KM, Laurence TA, Neuhauser D, Kovchegov Y, Weiss S.

J Phys Chem B. 2006 Nov 9;110(44):22103-24.

47.

Photon-Counting H33D Detector for Biological Fluorescence Imaging.

Michalet X, Siegmund OH, Vallerga JV, Jelinsky P, Millaud JE, Weiss S.

Nucl Instrum Methods Phys Res A. 2006 Nov 1;567(1):133.

48.

Single-molecule fluorescence studies of protein folding and conformational dynamics.

Michalet X, Weiss S, Jäger M.

Chem Rev. 2006 May;106(5):1785-813. Review. No abstract available.

49.

Using photon statistics to boost microscopy resolution.

Michalet X, Weiss S.

Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):4797-8. Epub 2006 Mar 20. No abstract available.

50.

Development of an ultrafast single photon counting imager for single molecule imaging.

Ohnuki T, Michalet X, Tripathi A, Weiss S, Arisaka K.

Proc SPIE Int Soc Opt Eng. 2006 Feb;6092. pii: 60920P. doi: 10.1117/12.658191.

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