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Items: 1 to 50 of 255

1.

Vaccine Adjuvants Derivatized from Momordica Saponins I and II.

Wang P, Ding X, Kim H, Škalamera Đ, Michalek SM, Zhang P.

J Med Chem. 2019 Nov 14;62(21):9976-9982. doi: 10.1021/acs.jmedchem.9b01511. Epub 2019 Oct 28.

PMID:
31657920
2.

Synthesis and Evaluation of QS-7-Based Vaccine Adjuvants.

Wang P, Škalamera Đ, Sui X, Zhang P, Michalek SM.

ACS Infect Dis. 2019 Jun 14;5(6):974-981. doi: 10.1021/acsinfecdis.9b00039. Epub 2019 Mar 28.

PMID:
30920199
3.

Synthesis and Evaluation of a QS-17/18-Based Vaccine Adjuvant.

Wang P, Škalamera Đ, Sui X, Zhang P, Michalek SM.

J Med Chem. 2019 Feb 14;62(3):1669-1676. doi: 10.1021/acs.jmedchem.8b01997. Epub 2019 Jan 18.

PMID:
30656932
4.

Glycosyltransferase-Mediated Biofilm Matrix Dynamics and Virulence of Streptococcus mutans.

Rainey K, Michalek SM, Wen ZT, Wu H.

Appl Environ Microbiol. 2019 Feb 20;85(5). pii: e02247-18. doi: 10.1128/AEM.02247-18. Print 2019 Mar 1.

5.

Inhibition of Streptococcus mutans Biofilms by the Natural Stilbene Piceatannol Through the Inhibition of Glucosyltransferases.

Nijampatnam B, Zhang H, Cai X, Michalek SM, Wu H, Velu SE.

ACS Omega. 2018 Jul 31;3(7):8378-8385. doi: 10.1021/acsomega.8b00367. Epub 2018 Jul 30.

6.

Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence.

Zhang Q, Nijampatnam B, Hua Z, Nguyen T, Zou J, Cai X, Michalek SM, Velu SE, Wu H.

Sci Rep. 2017 Jul 20;7(1):5974. doi: 10.1038/s41598-017-06168-1.

7.

Phenotype and Function of Myeloid-Derived Suppressor Cells Induced by Porphyromonas gingivalis Infection.

Su L, Xu Q, Zhang P, Michalek SM, Katz J.

Infect Immun. 2017 Jul 19;85(8). pii: e00213-17. doi: 10.1128/IAI.00213-17. Print 2017 Aug.

8.

Synthesis and Evaluation of QS-21-Based Immunoadjuvants with a Terminal-Functionalized Side Chain Incorporated in the West Wing Trisaccharide.

Wang P, Devalankar DA, Dai Q, Zhang P, Michalek SM.

J Org Chem. 2016 Oct 21;81(20):9560-9566. Epub 2016 Oct 13.

9.

8-Hydroxyquinolines Are Boosting Agents of Copper-Related Toxicity in Mycobacterium tuberculosis.

Shah S, Dalecki AG, Malalasekera AP, Crawford CL, Michalek SM, Kutsch O, Sun J, Bossmann SH, Wolschendorf F.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5765-76. doi: 10.1128/AAC.00325-16. Print 2016 Oct.

10.

IL-1R/TLR2 through MyD88 Divergently Modulates Osteoclastogenesis through Regulation of Nuclear Factor of Activated T Cells c1 (NFATc1) and B Lymphocyte-induced Maturation Protein-1 (Blimp1).

Chen Z, Su L, Xu Q, Katz J, Michalek SM, Fan M, Feng X, Zhang P.

J Biol Chem. 2015 Dec 11;290(50):30163-74. doi: 10.1074/jbc.M115.663518. Epub 2015 Oct 19.

11.

Cariogenicity of Streptococcus mutans glucan-binding protein deletion mutants.

Lynch DJ, Michalek SM, Zhu M, Drake D, Qian F, Banas JA.

Oral Health Dent Manag. 2013 Dec;12(4):191-9.

12.

Novel catanionic surfactant vesicle vaccines protect against Francisella tularensis LVS and confer significant partial protection against F. tularensis Schu S4 strain.

Richard K, Mann BJ, Stocker L, Barry EM, Qin A, Cole LE, Hurley MT, Ernst RK, Michalek SM, Stein DC, Deshong P, Vogel SN.

Clin Vaccine Immunol. 2014 Feb;21(2):212-26. doi: 10.1128/CVI.00738-13. Epub 2013 Dec 18.

13.

Role of mTOR downstream effector signaling molecules in Francisella tularensis internalization by murine macrophages.

Edwards MW, Aultman JA, Harber G, Bhatt JM, Sztul E, Xu Q, Zhang P, Michalek SM, Katz J.

PLoS One. 2013 Dec 3;8(12):e83226. doi: 10.1371/journal.pone.0083226. eCollection 2013.

14.

Synthesis of QS-21-based immunoadjuvants.

Wang P, Dai Q, Thogaripally P, Zhang P, Michalek SM.

J Org Chem. 2013 Nov 15;78(22):11525-34. doi: 10.1021/jo402118j. Epub 2013 Nov 5.

15.

Regional myocardial sympathetic denervation predicts the risk of sudden cardiac arrest in ischemic cardiomyopathy.

Fallavollita JA, Heavey BM, Luisi AJ Jr, Michalek SM, Baldwa S, Mashtare TL Jr, Hutson AD, Dekemp RA, Haka MS, Sajjad M, Cimato TR, Curtis AB, Cain ME, Canty JM Jr.

J Am Coll Cardiol. 2014 Jan 21;63(2):141-9. doi: 10.1016/j.jacc.2013.07.096. Epub 2013 Sep 25.

16.

Regulation of Th1 cells and experimental autoimmune encephalomyelitis by glycogen synthase kinase-3.

Beurel E, Kaidanovich-Beilin O, Yeh WI, Song L, Palomo V, Michalek SM, Woodgett JR, Harrington LE, Eldar-Finkelman H, Martinez A, Jope RS.

J Immunol. 2013 May 15;190(10):5000-11. doi: 10.4049/jimmunol.1203057. Epub 2013 Apr 19.

17.

Copper-boosting compounds: a novel concept for antimycobacterial drug discovery.

Speer A, Shrestha TB, Bossmann SH, Basaraba RJ, Harber GJ, Michalek SM, Niederweis M, Kutsch O, Wolschendorf F.

Antimicrob Agents Chemother. 2013 Feb;57(2):1089-91. doi: 10.1128/AAC.01781-12. Epub 2012 Dec 17.

18.

A mucosal subunit vaccine protects against lethal respiratory infection with Francisella tularensis LVS.

Ashtekar AR, Katz J, Xu Q, Michalek SM.

PLoS One. 2012;7(11):e50460. doi: 10.1371/journal.pone.0050460. Epub 2012 Nov 28.

19.

Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to Porphyromonas gingivalis.

Gaddis DE, Maynard CL, Weaver CT, Michalek SM, Katz J.

J Leukoc Biol. 2013 Jan;93(1):21-31. doi: 10.1189/jlb.0512220. Epub 2012 Oct 17.

20.

YidC1 and YidC2 are functionally distinct proteins involved in protein secretion, biofilm formation and cariogenicity of Streptococcus mutans.

Palmer SR, Crowley PJ, Oli MW, Ruelf MA, Michalek SM, Brady LJ.

Microbiology. 2012 Jul;158(Pt 7):1702-12. doi: 10.1099/mic.0.059139-0. Epub 2012 Apr 13.

21.

Molecular basis of requirement of receptor activator of nuclear factor κB signaling for interleukin 1-mediated osteoclastogenesis.

Jules J, Zhang P, Ashley JW, Wei S, Shi Z, Liu J, Michalek SM, Feng X.

J Biol Chem. 2012 May 4;287(19):15728-38. doi: 10.1074/jbc.M111.296228. Epub 2012 Mar 13.

22.

Differentiation of banding patterns between Streptococcus mutans and Streptococcus sobrinus isolates in rep-PCR using ERIC primer.

Okada T, Takada K, Fujita K, Ikemi T, Osgood RC, Childers NK, Michalek SM.

J Oral Microbiol. 2011;3. doi: 10.3402/jom.v3i0.7190. Epub 2011 Dec 2.

23.

Contribution of a Streptococcus mutans antigen expressed by a Salmonella vector vaccine in dendritic cell activation.

Xu Q, Katz J, Zhang P, Ashtekar AR, Gaddis DE, Fan M, Michalek SM.

Infect Immun. 2011 Sep;79(9):3792-800. doi: 10.1128/IAI.05338-11. Epub 2011 Jul 11.

24.

TLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NF-kappaB.

Zhang P, Liu J, Xu Q, Harber G, Feng X, Michalek SM, Katz J.

J Biol Chem. 2011 Jul 8;286(27):24159-69. doi: 10.1074/jbc.M110.198085. Epub 2011 May 12.

25.

TLR4 signaling via MyD88 and TRIF differentially shape the CD4+ T cell response to Porphyromonas gingivalis hemagglutinin B.

Gaddis DE, Michalek SM, Katz J.

J Immunol. 2011 May 15;186(10):5772-83. doi: 10.4049/jimmunol.1003192. Epub 2011 Apr 15.

26.

Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cells.

Beurel E, Yeh WI, Michalek SM, Harrington LE, Jope RS.

J Immunol. 2011 Feb 1;186(3):1391-8. doi: 10.4049/jimmunol.1003511. Epub 2010 Dec 29.

28.

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3).

Beurel E, Michalek SM, Jope RS.

Trends Immunol. 2010 Jan;31(1):24-31. doi: 10.1016/j.it.2009.09.007. Epub 2009 Oct 14. Review.

29.

Requirement of TLR4 and CD14 in dendritic cell activation by Hemagglutinin B from Porphyromonas gingivalis.

Gaddis DE, Michalek SM, Katz J.

Mol Immunol. 2009 Aug;46(13):2493-504. doi: 10.1016/j.molimm.2009.05.022. Epub 2009 Jun 21.

30.

Molecular mechanism of the bifunctional role of lipopolysaccharide in osteoclastogenesis.

Liu J, Wang S, Zhang P, Said-Al-Naief N, Michalek SM, Feng X.

J Biol Chem. 2009 May 1;284(18):12512-23. doi: 10.1074/jbc.M809789200. Epub 2009 Mar 3.

31.

Glycogen synthase kinase-3beta (GSK3beta) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in mice.

Zhang P, Katz J, Michalek SM.

Mol Immunol. 2009 Feb;46(4):677-87. doi: 10.1016/j.molimm.2008.08.281. Epub 2008 Oct 17.

32.

TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis.

Ashtekar AR, Zhang P, Katz J, Deivanayagam CC, Rallabhandi P, Vogel SN, Michalek SM.

J Leukoc Biol. 2008 Dec;84(6):1434-46. doi: 10.1189/jlb.0308215. Epub 2008 Aug 15.

33.

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses.

Yang D, Chen Q, Su SB, Zhang P, Kurosaka K, Caspi RR, Michalek SM, Rosenberg HF, Zhang N, Oppenheim JJ.

J Exp Med. 2008 Jan 21;205(1):79-90. doi: 10.1084/jem.20062027. Epub 2008 Jan 14.

34.

Lipoteichoic acid is important in innate immune responses to gram-positive bacteria.

Seo HS, Michalek SM, Nahm MH.

Infect Immun. 2008 Jan;76(1):206-13. Epub 2007 Oct 22.

36.

Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophages.

Cole LE, Shirey KA, Barry E, Santiago A, Rallabhandi P, Elkins KL, Puche AC, Michalek SM, Vogel SN.

Infect Immun. 2007 Aug;75(8):4127-37. Epub 2007 May 21.

37.

Evidence that accumulation of mutants in a biofilm reflects natural selection rather than stress-induced adaptive mutation.

Banas JA, Miller JD, Fuschino ME, Hazlett KR, Toyofuku W, Porter KA, Reutzel SB, Florczyk MA, McDonough KA, Michalek SM.

Appl Environ Microbiol. 2007 Jan;73(1):357-61. Epub 2006 Nov 3.

38.

Immune response in humans to a nasal boost with Streptococcus mutans antigens.

Childers NK, Li F, Dasanayake AP, Li Y, Kirk K, Michalek SM.

Oral Microbiol Immunol. 2006 Oct;21(5):309-13.

PMID:
16922930
39.

Immunologic consequences of Francisella tularensis live vaccine strain infection: role of the innate immune response in infection and immunity.

Cole LE, Elkins KL, Michalek SM, Qureshi N, Eaton LJ, Rallabhandi P, Cuesta N, Vogel SN.

J Immunol. 2006 Jun 1;176(11):6888-99.

40.

Prediction of arrhythmic events with positron emission tomography: PAREPET study design and methods.

Fallavollita JA, Luisi AJ Jr, Michalek SM, Valverde AM, deKemp RA, Haka MS, Hutson AD, Canty JM Jr.

Contemp Clin Trials. 2006 Aug;27(4):374-88. Epub 2006 May 2.

PMID:
16647885
41.

Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS.

Katz J, Zhang P, Martin M, Vogel SN, Michalek SM.

Infect Immun. 2006 May;74(5):2809-16.

42.

Immunogenicity of Salmonella vector vaccines expressing SBR of Streptococcus mutans under the control of a T7-nirB (dual) promoter system.

Salam MA, Katz J, Zhang P, Hajishengallis G, Michalek SM.

Vaccine. 2006 Jun 5;24(23):5003-15. Epub 2006 Mar 31.

PMID:
16621196
43.

Lipoteichoic acid-induced nitric oxide production depends on the activation of platelet-activating factor receptor and Jak2.

Han SH, Kim JH, Seo HS, Martin MH, Chung GH, Michalek SM, Nahm MH.

J Immunol. 2006 Jan 1;176(1):573-9. Erratum in: J Immunol. 2006 Feb 15;176(4):2671.

45.

Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

Martin M, Rehani K, Jope RS, Michalek SM.

Nat Immunol. 2005 Aug;6(8):777-84. Epub 2005 Jul 10.

47.
48.

Comparative analysis of the antibacterial effects of combined mouthrinses on Streptococcus mutans.

Menendez A, Li F, Michalek SM, Kirk K, Makhija SK, Childers NK.

Oral Microbiol Immunol. 2005 Feb;20(1):31-4.

PMID:
15612942
50.

A Caries Vaccine? The state of the science of immunization against dental caries.

Russell MW, Childers NK, Michalek SM, Smith DJ, Taubman MA.

Caries Res. 2004 May-Jun;38(3):230-5. Review.

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