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Inspiratory resistive breathing induces MMP-9 and MMP-12 expression in the lung.

Toumpanakis D, Noussia O, Sigala I, Litsiou E, Loverdos K, Zacharatos P, Karavana V, Michailidou T, Magkou C, Zhou Z, Theocharis S, Vassilakopoulos T.

Am J Physiol Lung Cell Mol Physiol. 2015 Apr 1;308(7):L683-92. doi: 10.1152/ajplung.00133.2014. Epub 2015 Jan 16. Erratum in: Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15;309(2):L204.


Nitric oxide regulates cytokine induction in the diaphragm in response to inspiratory resistive breathing.

Sigala I, Zacharatos P, Boulia S, Toumpanakis D, Michailidou T, Parthenis D, Roussos C, Papapetropoulos A, Hussain SN, Vassilakopoulos T.

J Appl Physiol (1985). 2012 Nov;113(10):1594-603. doi: 10.1152/japplphysiol.00233.2012. Epub 2012 Sep 6.


MAPKs and NF-κB differentially regulate cytokine expression in the diaphragm in response to resistive breathing: the role of oxidative stress.

Sigala I, Zacharatos P, Toumpanakis D, Michailidou T, Noussia O, Theocharis S, Roussos C, Papapetropoulos A, Vassilakopoulos T.

Am J Physiol Regul Integr Comp Physiol. 2011 May;300(5):R1152-62. doi: 10.1152/ajpregu.00376.2010. Epub 2011 Feb 16.


Inspiratory resistive breathing induces acute lung injury.

Toumpanakis D, Kastis GA, Zacharatos P, Sigala I, Michailidou T, Kouvela M, Glynos C, Divangahi M, Roussos C, Theocharis SE, Vassilakopoulos T.

Am J Respir Crit Care Med. 2010 Nov 1;182(9):1129-36. doi: 10.1164/rccm.201001-0116OC. Epub 2010 Jul 9.


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